An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 101 - 125 of 891

  1. Associations of typical antibiotic residues with elderly blood lipids and dyslipidemia in West Anhui, China

    • Ecotoxicology and Environmental Safety
    • Growing evidence has indicated the association of clinical antibiotic use with abnormal blood lipid levels; however, no epidemiological study has examined the relationship of antibiotic exposure, probably derived from food chains, with blood lipid levels. This study investigated the relationships of urinary antibiotic levels with blood lipid levels and dyslipidemias in the older population.

      • Chemical contaminants
      • Antibiotic residues
  2. Melatonin improves mitochondrial function by preventing mitochondrial fission in cadmium-induced rat proximal tubular cell injury via SIRT1–PGC-1α pathway activation

    • Ecotoxicology and Environmental Safety
    • Melatonin is an indoleamine produced in the pineal gland and has many physiological roles. There is increasing evidence that melatonin ameliorates cadmium (Cd)-induced nephrotoxicity. The potential protective impact of melatonin against Cd-induced nephrotoxicity and the mechanisms behind this protection are unknown.

      • Chemical contaminants
      • Heavy Metals
  3. Dynamics of fungal and bacterial communities in different types of soil ageing with different dosages of cadmium

    • Ecotoxicology and Environmental Safety
    • This study investigated the structure of fungal and bacterial communities in different types of Cd-contaminated soils.

      • Chemical contaminants
      • Heavy Metals
  4. Arsenic exposure during juvenile and puberty significantly affected reproductive system development of female SD rats

    • Ecotoxicology and Environmental Safety
    • Infertility affects about 10–15% couples over the world, among which a large number of cases the underlying causes are still unclear.

      • Chemical contaminants
      • Heavy Metals
  5. Physiological and proteomic responses of Chlamydomonas reinhardtii to arsenate and lead mixtures

    • Ecotoxicology and Environmental Safety
    • Arsenic (As) and lead (Pb) are frequently emitted from various sources into environment, but microbial responses to their combined toxicity have not been systematically investigated.

      • Chemical contaminants
      • Heavy Metals
  6. Sodium para-aminosalicylic acid ameliorates lead-induced hippocampal neuronal apoptosis by suppressing the activation of the IP3R-Ca2+-ASK1-p38 signaling pathway

    • Ecotoxicology and Environmental Safety
    • Lead (Pb) is a naturally occurring heavy metal, which can damage the brain and affect learning and memory. Sodium para-aminosalicylic acid (PAS-Na), a non-steroidal anti-inflammatory drug, can readily cross the blood-brain barrier. Our previous studies have found that PAS-Na alleviated Pb-induced hippocampal ultrastructural damage and neurodegeneration, but the mechanism has yet to be defined.

      • Chemical contaminants
      • Heavy Metals
  7. New insight into the effect of riluzole on cadmium tolerance and accumulation in duckweed (Lemna turionifera)

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) damages plant photosynthesis, affects roots and leaves growth, and triggers molecular responses. Riluzole (RIL), which protected neuronal damage via inhibiting excess Glu release in animals, has been found to improve Cd tolerance in duckweed in this study.

      • Chemical contaminants
      • Heavy Metals
  8. Comparative proteomic analysis reveals insights into the response of Cryptolaemus montrouzieri to bottom-up transfer of cadmium and lead across a multi-trophic food chain

    • Ecotoxicology and Environmental Safety
    • Contamination of agro-ecosystems with heavy metals can affect the development and reproduction of insect natural enemies.

      • Chemical contaminants
      • Heavy Metals
  9. Effect of boron on cadmium uptake and expression of Cd transport genes at different growth stages of wheat (Triticum aestivum L.)

    • Ecotoxicology and Environmental Safety
    • Boron (B) is an essential microelement for plant growth and has been shown to reduce cadmium (Cd) toxicity in wheat through modulating gene expression. However, there is not enough information about the effects of different applications of B fertilizer on the accumulation of Cd, particularly throughout the wheat growth period. This experiment employed two different B fertilization methods.

      • Chemical contaminants
      • Heavy Metals
  10. Magnetic polymer particles as a highly efficient and facile cleanup adsorbent for multi-pesticide residues analysis in aquatic products

    • Ecotoxicology and Environmental Safety
      • Chemical contaminants
      • Pesticide residues
  11. Zearalenone affects the growth of endometriosis via estrogen signaling and inflammatory pathways

    • Ecotoxicology and Environmental Safety
    • Endometriosis is a chronic, inflammatory, estrogen-dependent gynecological disease characterized by the growth of endometrial stromal cells and glands outside the uterine cavity in response to hormones, which commonly occurs in reproductive-age women. Zearalenone (ZEA) is a toxic metabolite produced by Fusarium, which acts as estrogen activity because of the similarity of its structure to estrogen.

      • Natural toxins
      • Mycotoxins
  12. Dihydroartemisinin alleviates deoxynivalenol induced liver apoptosis and inflammation in piglets

    • Ecotoxicology and Environmental Safety
    • Deoxynivalenol (DON) is one of the mycotoxins that contaminate cereals and feed, thereby endangering human and animal health. Dihydroartemisinin (DHA), a derivative of artemisinin, has anti-inflammatory and antioxidant functions in addition to anti-malaria and anti-cancer.

      • Natural toxins
      • Mycotoxins
  13. Transcriptomics-based analysis of co-exposure of cadmium (Cd) and 2,2',4,4'-tetrabromodiphenyl ether (BDE-47) indicates mitochondrial dysfunction induces NLRP3 inflammasome and inflammatory cell death in renal tubular epithelial cells

    • Ecotoxicology and Environmental Safety
    • Environmental pollution often releases multiple contaminants resulting in as yet largely uncharacterized additive toxicities. Cadmium (Cd) is a widespread pollutant that induces nephrotoxicity in animal models and humans.

      • Chemical contaminants
      • Heavy Metals
  14. Total arsenic, dimethylarsinic acid, lead, cadmium, total mercury, methylmercury and hypertension among Asian populations in the United States: NHANES 2011–2018

    • Ecotoxicology and Environmental Safety
    • Background Non-Hispanic Asians (NHA) in USA have been reported with higher arsenic (As), lead (Pb), cadmium (Cd), mercury (Hg) and their specific species levels, comparing with non-NHA.

      • Chemical contaminants
      • Heavy Metals
  15. Physiological and rhizospheric response characteristics to cadmium of a newly identified cadmium accumulator Coreopsis grandiflora Hogg. (Asteraceae)

    • Ecotoxicology and Environmental Safety
    • Screening for superior cadmium (Cd) phytoremediation resources and uncovering the mechanisms of plant response to Cd are important for effective phytoremediation of Cd-polluted soils. In this study, the characteristics of Coreopsis grandiflora related to Cd tolerance and accumulation were analyzed to evaluate its Cd phytoremediation potential.

      • Chemical contaminants
      • Heavy Metals
  16. Chloride application weakens cadmium immobilization by lime in paddy rice soil

    • Ecotoxicology and Environmental Safety
    • Contamination of agricultural products by cadmium (Cd) is a global health problem, causing chronic abnormalities. The consumption of rice, the most-consumed foods, is an important exposure route of Cd to human body. Chloride (Cl-) is reported to increase Cd uptake by rice; however, the effect on Cd uptake and accumulation by rice in the presence of lime is not clear.

      • Chemical contaminants
      • Heavy Metals
  17. Role of endoplasmic reticulum stress in cadmium-induced hepatocyte apoptosis and the protective effect of quercetin

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is one of the most toxic environmental pollutants. Quercetin (Que) is a kind of natural flavonoid with neuroprotective, antioxidant, and free-radical scavenging pharmacological activities. However, whether Que has the protective effect of on Cd-induced rat hepatocyte injury is unclear. This study aimed to determine the protective effect of Que on Cd-induced hepatotoxicity in vivo and in vitro.

      • Chemical contaminants
      • Heavy Metals
  18. Silicon-enhanced tolerance to cadmium toxicity in soybean by enhancing antioxidant defense capacity and changing cadmium distribution and transport

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is a widely distributed heavy metal that is toxic to plants and humans. Although silicon (Si) has been reported to reduce Cd accumulation and toxicity in plants, evidence on the functions of Si and its mechanisms in the possible alleviation of soybean are limited. Therefore, a controlled experiment was conducted to investigate the impacts and mechanisms of Si on Cd retention in soybean.

      • Chemical contaminants
      • Heavy Metals
  19. Transcriptomic responses of the zearalenone (ZEN)-detoxifying yeast Apiotrichum mycotoxinivorans to ZEN exposure

    • Ecotoxicology and Environmental Safety
    • Zearalenone (ZEN) is a potent oestrogenic mycotoxin that is mainly produced by Fusarium species and is a serious environmental pollutant in animal feeds. Apiotrichum mycotoxinivorans has been widely used as a feed additive to detoxify ZEN. However, the effects of ZEN on A.

      • Natural toxins
      • Mycotoxins
  20. Toxic effects of the combined cadmium and Cry1Ab protein exposure on the protective and transcriptomic responses of Pirata subpiraticus

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) pollution poses a serious threat to agricultural production and paddy field fauna.

      • Chemical contaminants
      • Heavy Metals
  21. MiR-378a-3p/ SLC7A11 regulate ferroptosis in nerve injury induced by lead exposure

    • Ecotoxicology and Environmental Safety
    • An increasing number of studies have clarified that ferroptosis plays a vital role in neurodegenerative diseases, which is characterized by the accumulation of Fe2+, lipid peroxidation, and alteration of mitochondrial structure. However, whether ferroptosis is involved in nerve injury caused by lead exposure remains unclear. In this study, HT22 cells and mice were treated with lead acetate to investigate the role of ferroptosis in lead neurotoxicity.

      • Chemical contaminants
      • Heavy Metals
  22. Cadmium, lead and arsenic contamination in an abandoned nonferrous metal smelting site in southern China: Chemical speciation and mobility

    • Ecotoxicology and Environmental Safety
    • The investigation of chemical speciation of primary toxic metal(loid)s (Cd, Pb, and As) in soil profile in nonferrous metal smelting site is a key to the assessment of their mobility ch

      • Chemical contaminants
      • Heavy Metals
  23. A WRKY transcription factor, PyWRKY75, enhanced cadmium accumulation and tolerance in poplar

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) pollution has detrimental effects on the ecological environment and human health. Currently, phytoremediation is considered an environmentally friendly way to remediate Cd pollution.

      • Chemical contaminants
      • Heavy Metals
  24. Arsenic induces ferroptosis and acute lung injury through mtROS-mediated mitochondria-associated endoplasmic reticulum membrane dysfunction

    • Ecotoxicology and Environmental Safety
    • The goal of this study was to analyze whether mitochondria-associated endoplasmic reticulum membrane (MAMs) dysfunction mediated arsenic (As)-evoked pulmonary ferroptosis and acute lung injury (ALI).

      • Chemical contaminants
      • Heavy Metals
  25. Pesticide residues in beebread and honey in Apis cerana cerana and their hazards to honey bees and human

    • Ecotoxicology and Environmental Safety
    • The residue of pesticides in bee products such as beebread and honey threaten the survival of pollinators and human health. Apis cerana cerana is one of the leading managed honey bees in China. However, little is known about the residues of pesticides in hive products of A. c. cerana in China.

      • Chemical contaminants
      • Pesticide residues