Microbiological Research

Wed, 06/09/2021 - 06:06
Author(s): Haojie Ge, Kai Zhang, Dan Gu, Xiang Chen, Xin Wang, Guiqin Li, Hongji Zhu, Yingyan Chang, Ge Zhao, Zhiming Pan, Xin’an Jiao, Maozhi Hu The study of the interaction mechanism between bacteriophage and host is helpful in promoting development of bacteriophage applications. The mechanism of the interaction with the phage was studied by constructing the rfbN gene deletion and complemented...
Thu, 06/03/2021 - 06:13
Author(s): Pengji Zhou, Haiyan Huang, Jiaoyang Lu, Zirong Zhu, Junyan Xie, Liqiu Xia, Sisi Luo, Kexuan Zhou, Wenhui Chen, Xuezhi Ding Bacillus amyloliquefaciens X030 (BaX030) has broad-spectrum antibacterial activity against the fish pathogens Aeromonas hydrophila and Aeromonas veronii. To improve its antibacterial effect, BaX030 was subjected to compound mutagenesis of atmospheric and room...
Fri, 05/28/2021 - 06:07
Author(s): Min Liu, Xinyuan Zhu, Ce Zhang, Zhe Zhao Vibrio parahaemolyticus, a common foodborne pathogen, can form biofilms for survival in various environments and for bacterial transmission. Lux systems in Vibrio species are the typical two-component signal transduction systems, which have been demonstrated to contribute to various phenotypes; however, the functions of each homolog of the Lux...
Wed, 05/12/2021 - 06:07
Author(s): Ran Cai, Fen Gao, Junfeng Pan, Xinwei Hao, Zonglan Yu, Yichen Qu, Jialin Li, Dandan Wang, Yao Wang, Xihui Shen, Xingyu Liu, Yantao Yang Zinc homeostasis is crucial for the development and stress resistance of bacteria in the environment. Serial zinc sensing transcriptional regulators, zinc transporters and zinc binding proteins were found to maintain the zinc homeostasis in bacteria....
Wed, 01/06/2021 - 06:05
Author(s): Xin Wang, Yiluo Cheng, Wenting Zhang, Qin Lu, Guoyuan Wen, Qingping Luo, Huabin Shao, Zishu Pan, Tengfei Zhang Salmonella Pullorum is a pathogen specific to birds that can cause Pullorum disease in young chickens and lead to considerable economic losses in the poultry industry. During transmission and infection, S. Pullorum will encounter various environmental stresses and host...
Mon, 12/28/2020 - 06:05
Author(s): Yaonan Wang, Guifeng Liu, Jian Zhang, Dan Gu, Maozhi Hu, Yunzheng Zhang, Zhiming Pan, Shizhong Geng, Xin’an Jiao Salmonella spp. can survive and replicate in macrophage cells to cause persistent infection, SpiC is a necessary T3SS effector, but its pathogenic mechanism is still not known completely. In our study, Salmonella Enteritidis spiC mutant (SEΔspiC) was found to have stronger...
Sat, 12/05/2020 - 06:15
Author(s): Jabila Mary Thankaraj Rajam, Rajaretinam Rajesh Kannan, Muthamil Iniyan Appadurai, Carlton Ranjith Wilson Alphonse, Nandhagopal Soundarapandian, Vinita Vishwakarma, Prakash Vincent Samuel Gnana β-lactamase inhibitors are potent synergistic drugs to deteriorate the multidrug-resistant bacteria. Here, we report the β-lactamase inhibitory ability of kalafungin isolated from a marine...
Fri, 10/09/2020 - 06:10
Author(s): M.A. Abo-Kadoum, Mohammed Assad, Yongdong Dai, Nzungize Lambert, Ulrich Aymard Ekomi Moure, Adel Eltoukhy, Stech A.E. Nazou, Asmaa Moaaz, Jianping Xie Mycobacterium tuberculosis Rv2140c is a function unknown conserved phosphatidylethanolamine-binding protein (PEBP), homologous to Raf kinase inhibitor protein (RKIP) in human beings. To delineate its function, we heterologously expressed...
Sat, 09/19/2020 - 06:15
Author(s): Nehal Kamal, Zhiwei Liu, Chen Qian, Juanzi Wu, Xiaoxian Zhong Environmental pollution with heavy metals becomes an issue of serious concern worldwide. Cadmium is considered one which adversely affects living organisms. Recently, the usage of endophytic bacteria to enhance the plant growth and phytoremediation of heavy metals contaminated sites is gaining great attention. The current...
Sat, 06/20/2020 - 06:08
Author(s): Paritosh Parmar, Arpit Shukla, Dweipayan Goswami, Shailendra Gaur, Baldev Patel, Meenu Saraf The current study depicts the isolation of luminescent bacteria from fish and squid samples that were collected from Veraval fish harbour. From Indian mackerel, total 14 and from squid, total 23 bioluminescent bacteria were isolated using luminescence agar medium. Two bioluminescent bacteria...
Sun, 05/17/2020 - 03:31
Author(s): Ke-Chuan Wang, Chih-Hung Huang, Pei-Ru Chang, Ming-Te Huang, Shiuh-Bin Fang In Salmonella Typhimurium (S. Typhimurium), lipopolysaccharide (LPS) anchored on the bacterial outer membrane is a major immune stimulus that can broadly activate immune cells and induce innate immune responses. wzxE is involved in bacterial LPS biosynthesis but has rarely been reported in Salmonella; wzxE...
Tue, 05/12/2020 - 03:30
Author(s): Debasish Kumar Dey, Sun Chul Kang Increasing multidrug-resistant pathogenic bacterial contamination in the environment has become the leading cause of food poisoning, resulting in life-threatening conditions due to late detection and limited therapeutic options. Escherichia coli O157:H7 is one such pathogen which is severely affecting the environmental livestock and ultimately leads to...
Sun, 03/22/2020 - 03:21
Author(s): Hongduo Bao, Yan Zhou, Khashayar Shahin, Hui Zhang, Fuliang Cao, Maoda Pang, Xuhui Zhang, Shujiao Zhu, Ademola Olaniran, Stefan Schmidt, Ran Wang S. Enteritidis continues to be the most common pathogen of farm animals and a major public health burden worldwide. Using bacteriophages is a potential alternative to antibiotics against S. Enteritidis infection. In this study, the genome...
Wed, 02/26/2020 - 03:22
Author(s): Yibei Zhang, Huanhuan Liu, Dan Gu, Xingxu Lu, Xiaohui Zhou, Xiaodong XiaVibrio parahaemolyticus is a common foodborne pathogen in seafood and represents a major threat to human health worldwide. In this study, we identified that PhoR, a histidine kinase, is involved in the regulation of swarming and flagella assembly. RNA sequencing analysis showed that 1122 genes were differentially...
Mon, 01/27/2020 - 03:23
Author(s): Shymaa Enany, Samira Zakeer, Ahmed A. SayedAbstractKlebsiella pneumoniae is a pathogenic bacterium that is responsible for a wide range of infections in humans. An increased rate of infections caused by multi-drug-resistant K. pneumoniae has been noted in the last two decades. The association between antimicrobial resistance and virulence is an important topic of study. Genomic tools...
Wed, 11/13/2019 - 03:22
Author(s): Zhi-Xiang Dong, Huan-Yuan Li, Yi-Fei Chen, Feng Wang, Xian-Yu Deng, Lian-Bing Lin, Qi-Lin Zhang, Ji-Lian Li, Jun GuoAbstractThe role of the gut microbiome in animal health has become increasingly evident. Although the structure of the gut microbiome of A. mellifera is well known, little is known about the dynamic change across different developmental stages. In this study, we explored...
Sun, 09/22/2019 - 03:20
Author(s): Prateek Kumar, Aditi Kundu, Munendra Kumar, Renu Solanki, Monisha Khanna KapurAbstractDue to emergence of drug resistant pathogens, nearly all available medicines are becoming ineffective against these life threatening pathogens so there is dire need for the discovery of compounds having unique modes of action. During our previous studies, actinomycetes designated as 196 and RI.24 were...
Sun, 09/22/2019 - 03:20
Author(s): Priyanka Aggarwal, Lifan Wei, Yuping Cao, Qin Liu, Julian A. Guttman, Qiyao Wang, Ka Yin LeungAbstractEdwardsiella bacteria cause economic losses to a variety of commercially important fish globally. Human infections are rare and result in a gastroenteritis-like illness. Because these bacteria are evolutionarily related to other Enterobacteriaceae and the host cytoskeleton is a common...
Sun, 09/22/2019 - 03:20
Author(s): Fatma Masmoudi, Nouha Abdelmalek, Slim Tounsi, Christopher A. Dunlap, Mohamed TriguiAbstractThe uses of halotolerant bacteria isolated from naturally saline habitats have the potential to be useful crop protection agents for plants in stressful conditions. These beneficial microbes generate several plant growth regulators and bioactive molecules, which enhance plant protection from...
Sun, 09/22/2019 - 03:20
Author(s): Tanya Clements, Thando Ndlovu, Wesaal KhanAbstractThe genus Serratia is a predominantly unexplored source of antimicrobial secondary metabolites. The aim of the current study was thus to isolate and evaluate the antimicrobial properties of biosurfactants produced by Serratia species. Forty-nine (n = 34 pigmented; n = 15 non-pigmented) biosurfactant producing Serratia strains were...
Sun, 09/22/2019 - 03:20
Author(s): Chia-Wei Chien, Yu-Feng Chan, Po-Shu Shih, Jung-En Kuan, Ke-Feng Wu, Cindy Wu, Whei-Fen WuAbstractMethionine is critical for variety of metabolic processes in biological organisms, acting as a precursor or intermediate for many final products. The last step for the synthesis of methionine is the methylation of homocysteine, which is catalyzed by MetE. Here, we use Salmonella enterica...