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Clostridium perfringens

Tue, 07/02/2019 - 20:00
Research progress into mechanisms of the anaerobe Clostridium perfringens associated diseases has been frustrated by the lack of reliable infection models. Wax moth larvae (Galleria mellonella) have emerged as a viable alternative to other models of infection since they are economic, survive at 37°C and require no specialist equipment. This study aims to establish to what extent G. mellonella...
Sun, 06/30/2019 - 07:43
Co‐encapsulation of lupulon and xanthohumol, as major bioactive components of hop in lecithin‐based nanoliposomes was developed by sonication method. The procedure of production was optimized by considering the duration and the power of ultrasound device as well as the concentration of lecithin as variables for the Response Surface Methodology. The average particle size, ζ‐potential, and the...
Fri, 06/28/2019 - 01:07
Available online 27 June 2019 Author(s): Miaoyun Li, Lihan Huang, Yaodi Zhu, Qingying WeiAbstractRoasted chicken (RC) and braised beef (BB) are two important commercial products widely consumed in China. Prepared with a mixture of different spices and other ingredients, these products may be contaminated with Clostridium perfringens spores. The spores may germinate, outgrow, and multiply to a...
Thu, 06/27/2019 - 01:07
Publication date: Available online 26 June 2019 Innovative Food Science & Emerging TechnologiesAuthor(s): Hee-Jeong Hwang, Ji-Hyun Seo, Chanmin Jeong, Chan-Ick Cheigh, Myong-Soo ChungAbstractThe objective of this study was to measure the inactivation efficiencies of intense pulsed light (IPL) on six types of bacteria and determine how the efficiency values are related to the spectral...
Fri, 06/21/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 7, Page 1141-1147, July 2019.
Fri, 06/21/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 7, Page 1141-1147, July 2019.
Fri, 06/21/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 7, Page 1141-1147, July 2019.
Fri, 06/21/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 7, Page 1141-1147, July 2019.
Thu, 06/06/2019 - 00:00
Toxins, Vol. 11, Pages 326: Prevalence and Genetic Diversity of Toxin Genes in Clinical Isolates of Clostridium perfringens: Coexistence of Alpha-Toxin Variant and Binary Enterotoxin Genes (bec/cpile) Toxins doi: 10.3390/toxins11060326 Authors: Asami Matsuda Meiji Soe Aung Noriko Urushibara Mitsuyo Kawaguchiya Ayako Sumi Mayumi Nakamura Yuka Horino Masahiko Ito Satoshi...
Sun, 06/02/2019 - 20:00
The aim of this study was to evaluate the frequency of toxigenic C. difficile and C. perfringens infections at health care facility-onset (HCFO) and community-onset (CO), in two health care centers (HCC) in Bogot...
Thu, 05/02/2019 - 11:02
Bacteriophage lysins are compelling antimicrobial proteins whose biotechnological utility and evolvability would be aided by elevated stability. Lysin catalytic domains, which evolved as modular entities distinct from cell wall binding domains, can be classified into one of several families with highly conserved structure and function, many of which contain thousands of annotated homologous...
Wed, 05/01/2019 - 01:10
Available online 30 April 2019 Author(s): J. Sindelar, K. Glass, R. Hanson, J.G. Sebranek, J. Cordray, J.S. DicksonAbstractPork bellies and boneless hams were smoked or cooked using unusually long processes to determine the impact of extended come-up times on the populations of Clostridium perfringens, Salmonella enterica, Staphylococcus aureus and Listeria monocytogenes. The products were...
Mon, 04/29/2019 - 20:00
Integrative Analyses of Long Non-coding RNA and mRNA Involved in Piglet Ileum Immune Response to Clostridium perfringens Type C Infection Xiaoyu Huang1, Wenyang Sun1, Zunqiang Yan1, Hairen Shi1, Qiaoli Yang1, Pengfei Wang1, Shenggui Li1, Lixia Liu2, Shengguo Zhao1 and Shuangbao Gun1,3* 1College of Animal Science and Technology, Gansu Agricultural University, Lanzhou, China 2College of Life...
Thu, 04/25/2019 - 20:00
Role of Starter Cultures on the Safety of Fermented Meat Products Marta Laranjo1*, Maria Eduarda Potes1,2 and Miguel Elias1,3 1ICAAM-Instituto de Ciências Agrárias e Ambientais Mediterrânicas, Universidade de Évora, Pólo da Mitra, Évora, Portugal 2Departamento de Medicina Veterinária, Escola de Ciências e Tecnologia, Universidade de Évora, Pólo...
Mon, 04/22/2019 - 00:00
Toxins, Vol. 11, Pages 232: Clostridium perfringens Delta-Toxin Damages the Mouse Small Intestine Toxins doi: 10.3390/toxins11040232 Authors: Soshi Seike Masaya Takehara Keiko Kobayashi Masahiro Nagahama Clostridium perfringens strains B and C cause fatal intestinal diseases in animals. The secreted pore-forming toxin delta-toxin is one of the virulence factors of the strains, but...
Tue, 04/16/2019 - 20:00
Large-Scale Genomic Analyses and Toxinotyping of Clostridium perfringens Implicated in Foodborne Outbreaks in France Abakabir Mahamat Abdelrahim, Nicolas Radomski, Sabine Delannoy, Sofia Djellal, Marylène Le Négrate, Katia Hadjab, Patrick Fach, Jacques-Antoine Hennekinne, Michel-Yves Mistou and Olivier Firmesse* Université PARIS-EST, Agence Nationale de Sécurité...
Mon, 04/15/2019 - 00:00
Toxins, Vol. 11, Pages 225: Application of an Endothelial Cell Culture Assay for the Detection of Neutralizing Anti-Clostridium Perfringens Beta-Toxin Antibodies in a Porcine Vaccination Trial Toxins doi: 10.3390/toxins11040225 Authors: Olivia K. Richard Sven Springer Jacqueline Finzel Tobias Theuß Marianne Wyder Beatriz Vidondo Horst Posthaus Background: Beta-toxin (CPB) is...
Wed, 04/10/2019 - 01:14
Available online 9 April 2019 Author(s): Nan Zhang, Tisong Liang, Quan Jin, Cai Shen, Yifan Zhang, Pu JingAbstractAntibiotic-associated diarrhea (AAD) is a common adverse effect of antibiotic treatment. The study was to evaluate effects of Chinese yam (Dioscorea opposita Thunb.) on AAD, and changes of intestinal microbiota and short-chain fatty acids (SCFA). AAD model was established using Balb/c...
Mon, 03/25/2019 - 11:00
Clostridium perfringens enterotoxin (CPE) is a pore-forming toxin that causes the symptoms of common bacterial food poisoning and several non-foodborne human gastrointestinal diseases, including antibiotic-associated diarrhea and sporadic diarrhea. In some cases, CPE-mediated disease can be very severe or fatal due to the involvement of enterotoxemia. Therefore, the development of potential...
Sat, 03/23/2019 - 00:00
Toxins, Vol. 11, Pages 177: Targeted Mass Spectrometry Analysis of Clostridium perfringens Toxins Toxins doi: 10.3390/toxins11030177 Authors: Miloslava Duracova Jana Klimentova Alena Myslivcova Fucikova Lenka Zidkova Valeria Sheshko Helena Rehulkova Jiri Dresler Zuzana Krocova Targeted proteomics recently proved to be a technique for the detection and absolute quantification...
Fri, 03/01/2019 - 00:00
Toxins, Vol. 11, Pages 138: Two Clostridium perfringens Type E Isolates in France Toxins doi: 10.3390/toxins11030138 Authors: Laure Diancourt Jean Sautereau Alexis Criscuolo Michel R. Popoff Clostridium perfringens type E is a less frequently isolated C. perfringens type and has not previously been reported in France. We have characterized two recent type E isolates, C. perfringens...
Sun, 02/24/2019 - 01:12
Available online 20 February 2019 Author(s): C.A Oliveira Júnior, R.O.S Silva, A.P Lage, F.M Coura, C.P Ramos, A.A. Alfieri, R.M.C Guedes, F.C.F LobatoAbstractNeonatal porcine diarrhea (NPD) is a current problem on pig farms and is caused by several enteropathogens. Among them, Clostridioides difficile stands out due to its importance in piglets and zoonotic potential. A non-toxigenic strain of C...
Sun, 02/24/2019 - 01:12
Available online 21 February 2019 Author(s): Santosh Keisam, Ngangyola Tuikhar, Giasuddin Ahmed, Kumaraswamy JeyaramAbstractThe microbial risk involved with natural food fermentation is largely unknown. Here, we report the prevalence of enteric bacterial pathogens in the traditional fermented foods marketed in Northeast region of India. A total of 682 samples of 39 food types (broadly categorized...
Sun, 02/10/2019 - 01:10
Publication date: Available online 8 February 2019 Innovative Food Science & Emerging TechnologiesAuthor(s): Sang Hui Lee, Juhui Choe, Dong Jin Shin, Hae In Yong, Yukyung Choi, Yohan Yoon, Cheorun JoAbstractWe evaluated the combined effect of high pressure (HP) and vinegar addition on control of Clostridium perfringens and quality in emulsion-type pork sausages. Sausages were manufactured...
Sat, 02/09/2019 - 01:13
Available online 7 February 2019 Author(s): Serap Cosansu, Vijay K. Juneja, Marangeli Osoria, Sudarsan MukhopadhyayAbstractThe heat resistance (57.5–65 °C) of a three-strain cocktail of Clostridium perfringens vegetative cells in sous vide processed ground beef supplemented with 0–3% grape seed extract (GSE) was quantified. The surviving cell population was enumerated on tryptose–sulfite–...
Thu, 01/24/2019 - 11:00
Eimeria tenella can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well recognized; however, less is known about the secondary effects that infection may have on other gut pathogens. Campylobacter jejuni is the leading cause of human bacterial foodborne disease in many countries and has been...
Wed, 01/23/2019 - 11:00
Diet is a major determinant of intestinal microbiome composition. While studies have evaluated microbiome responses to diet variation, less is understood about how the act of feeding influences the microbiome, independent of diet type. Here, we use the clownfish Premnas biaculeatus, a species reared commonly in ornamental marine aquaculture, to test how the diversity, predicted gene content, and...
Wed, 01/09/2019 - 01:01
Available online 7 January 2019 Author(s): D. Lepp, S. Ojha, I. Mehdizadeh Gohari, B. Chakravarty, J.F. Prescott, J. GongAbstractNecrotic enteritis (NE) is an economically important disease of broiler chickens that is caused primarily by Clostridium perfringens strains that produce the NetB toxin. It is controlled in North America principally through the application of in-feed antimicrobials, but...
Fri, 12/21/2018 - 00:00
Toxins, Vol. 11, Pages 1: Multiple Parameters Beyond Lipid Binding Affinity Drive Cytotoxicity of Cholesterol-Dependent Cytolysins Toxins doi: 10.3390/toxins11010001 Authors: Sucharit Ray Roshan Thapa Peter A. Keyel The largest superfamily of bacterial virulence factors is pore-forming toxins (PFTs). PFTs are secreted by both pathogenic and non-pathogenic bacteria. PFTs sometimes kill...
Wed, 12/05/2018 - 01:08
Publication date: 16 February 2019 , Volume 291Author(s): Yuki Wakabayashi, Hirofumi Nariya, Mayo Yasugi, Tomomi Kuwahara, Mahfuzur R. Sarker, Masami MiyakeAbstractClostridium perfringens type F is a spore-forming anaerobe that causes bacterial food-borne illness in humans. The disease develops when ingested vegetative cells reach the intestinal tract and begin to form spores that produce the...
Tue, 12/04/2018 - 16:08
Publication date: December 2018 , Volume 227Author(s): Jake A. Lacey, Dragana Stanley, Anthony L. Keyburn, Mark Ford, Honglei Chen, Priscilla Johanesen, Dena Lyras, Robert J. MooreAbstractProblem addressed: Clostridium perfringens is the etiological agent of necrotic enteritis in chickens. As necrotic enteritis is a gastrointestinal disease, the interactions of pathogenic C. perfringens strains...
Tue, 11/20/2018 - 12:35
Clostridium perfringens type F (formerly enterotoxigenic C. perfringens type A) strains produce an enterotoxin (CPE) to cause acute cases of food poisoning and chronic nonfoodborne human gastrointestinal diseases (NFD), e.g., antibiotic-associated diarrhea (AAD). NFD strains also produce NanI sialidase, an extracellular enzyme that releases sialic acids from sialyated host macromolecules. Recent...
Sat, 11/17/2018 - 19:00
ABSTRACTIt was hypothesized that dietary inclusion of Bacillus subtilis DSM 32315 could inhibit Clostridium perfringens induced necrotic enteritis (NE), thereby improving broiler performance. Male, d 0 chicks were randomly assigned 14 birds/pen, 11 pens/treatment in 3 treatments: a basal diet (control), a coccidiostat fed control (Narasin), and a direct fed microbial (DFM) B. subtilis DSM 32315...
Tue, 11/13/2018 - 01:11
Ting Huang, Biao Gao, Wen-Lu Chen, Rong Xiang, Ming-Gui Yuan, Zhi-Hong Xu, Xin-Yu Peng
Wed, 11/07/2018 - 17:00
Iman Mehdizadeh Gohari, Eric K. Brefo-Mensah, Michael Palmer, Patrick Boerlin, John F. Prescott NetF-producing type A Clostridium perfringens is an important cause of canine and foal necrotizing enteritis. NetF, related to the β-sheet pore-forming Leukocidin/Hemolysin superfamily, is considered a major virulence factor for this disease. The main purpose of this work is to demonstrate the pore-...
Mon, 10/08/2018 - 00:00
Toxins, Vol. 10, Pages 405: Interaction of Clostridium perfringens Iota Toxin and Lipolysis-Stimulated Lipoprotein Receptor (LSR) Toxins doi: 10.3390/toxins10100405 Authors: Masahiro Nagahama Masaya Takehara Keiko Kobayashi Iota toxin produced by Clostridium perfringens is a binary, actin ADP-ribosylating toxin that is organized into the enzymatically active component Ia and the...
Wed, 10/03/2018 - 20:00
ABSTRACTThe objective of this experiment was to study the effects of dietary zinc (Zn) source on gene expression of Zn transporters (metallothionein [MT], ZIP 3, 5, 8, 9, 10, 11, 13, and 14, and ZnT 1, 4, 5, 6, 7, 9, and 10) in the jejunum and cecal tonsils of broilers challenged with coccidia or coccidia plus Clostridium perfringens. A 2 × 2 factorial design was used with 2 Zn sources (90 mg Zn/...
Thu, 09/27/2018 - 17:00
Anna-Lena Ziese, Jan S. Suchodolski, Katrin Hartmann, Kathrin Busch, Alexandra Anderson, Fatima Sarwar, Natalie Sindern, Stefan Unterer Introduction The impact of probiotics on dogs with acute hemorrhagic diarrhea syndrome (AHDS) has not been evaluated so far. The study aim was to assess the effect of probiotic treatment on the clinical course, intestinal microbiome, and toxigenic Clostridium...
Fri, 09/21/2018 - 11:30
Clostridium perfringens type F strains, which produce C. perfringens enterotoxin (CPE), are a major cause of gastrointestinal infections, including the second most prevalent bacterial foodborne illness and 5 to 10% cases of antibiotic-associated diarrhea. Virulence of type F strains is primarily ascribable to CPE, which is synthesized only during sporulation. Many type F strains also produce NanI...
Wed, 09/19/2018 - 01:11
Available online 17 September 2018 Author(s): Hamzah M. Al-Qadiri, Stephanie Smith, Aleksandra Checinska Sielaff, Byju N. Govindan, Mohamed Ziyaina, Nivin Al-Alami, Barbara RascoAbstractBactericidal activity of neutral electrolyzed water (NEW) was investigated against endospore forming Bacillus cereus and Clostridium perfringens in cell suspensions and artificially inoculated onto the surface of...
Sun, 09/16/2018 - 20:00
AbstractNecrotic enteritis toxin B (NetB)-producing Clostridium perfringens (CP) type A is the etiological agent of necrotic enteritis (NE) – an economically significant disease in broiler chickens. Understanding the immune response to CP infection in broiler chickens is becoming important to develop effective vaccines against NE. An experiment was conducted to determine the expression levels of...
Wed, 08/22/2018 - 00:00
Toxins, Vol. 10, Pages 341: Clostridium perfringens Enterotoxin: The Toxin Forms Highly Cation-Selective Channels in Lipid Bilayers Toxins doi: 10.3390/toxins10090341 Authors: Roland Benz Michel R. Popoff One of the numerous toxins produced by Clostridium perfringens is Clostridium perfringens enterotoxin (CPE), a polypeptide with a molecular mass of 35.5 kDa exhibiting three different...
Sat, 08/11/2018 - 01:12
Available online 10 August 2018 Author(s): Niroshan Thanthrige-Don, Oliver Lung, Tara Furukawa-Stoffer, Cody Buchanan, Tomy Joseph, Dale L. Godson, John Gilleard, Trevor Alexander, Aruna AmbagalaAbstractRespiratory and enteric diseases continue to be two major causes of economic losses to the cattle industry worldwide. Despite their multifactorial etiology, the currently available diagnostic...
Wed, 08/01/2018 - 11:00
Quantitative information regarding the presence of Escherichia coli, intestinal enterococci, and Clostridium perfringens in poikilotherms is notably scarce. Therefore, this study was designed to allow a systematic comparison of the occurrence of these standard fecal indicator bacteria (SFIB) in the excreta of wild homeothermic (ruminants, boars, carnivores, and birds) and poikilothermic (...
Fri, 07/20/2018 - 20:00
ABSTRACTNecrotic enteritis (NE) caused by Clostridium perfringens has emerged as an important disease associated with major economic losses in the poultry industry worldwide. The ban and voluntary withdraw of antimicrobial growth promoters used to control NE have resulted in resurgence of NE. Moreover, consumer demand for antibiotic free poultry product has continued to grow. The presence of the...
Thu, 06/21/2018 - 11:05
Clostridium perfringens enterotoxin (CPE) is responsible for the gastrointestinal symptoms of C. perfringens type A food poisoning and some cases of nonfoodborne gastrointestinal diseases, such as antibiotic-associated diarrhea. In the presence of certain predisposing medical conditions, this toxin can also be absorbed from the intestines to cause enterotoxemic death. CPE action in vivo involves...

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