Dioxins

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Fri, 11/15/2019 - 03:32
Author(s): Yuting Chen, Yifan Wu, Weiwei Xiao, Hansi Jia, Hansruedi Glatt, Ming Shi, Yungang LiuAbstractPolychlorinated biphenyls (PCBs) are persistent organic pollutants and human carcinogens. It was reported that rat CYP1A1 and catfish CYP1A can hydroxylate 3,3',4,4',5-pentachlorobiphenyl (PCB 126) and 3,3',4,4'-tetrachlorobiphenyl (PCB 77), while potential roles of other CYP1 enzymes in the...
Fri, 11/08/2019 - 03:33
Author(s): Chenyang Xu, Jicheng Hu, Jing Wu, Baokai Wei, Zhenlei Zhu, Liwen Yang, Tingting Zhou, Jun JinAbstractSeventeen soil samples collected in an industrial park located in Ningxia Province, Northwestern China were analyzed for polychlorinated naphthalenes (PCNs), polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs), and polychlorinated biphenyls (PCBs). The PCN, PCDD/F, and PCB...
Wed, 10/30/2019 - 03:35
Author(s): Jelena Maric, Teresa Berdugo Vilches, Sébastien Pissot, Isabele Cañete Vela, Marianne Gyllenhammar, Martin SeemannAbstractEmissions of dioxins and furans during the gasification of Automotive Shredder Residue (ASR) were investigated. The experimental work was carried out in a Dual Fluidized Bed (DFB) system, which consists of a 2–4-MWth gasifier that is fluidized with steam, and an...
Sat, 10/26/2019 - 03:50
by Khushbu Salian, Vladimir Strezov, Tim J. Evans, Mark Taylor, Peter F. Nelson Industrial sources, including iron ore sintering, municipal waste incineration and non-ferrous metal processing have been prominent emitters of dioxins to the environment. With the expanding industrial sectors, many international conventions were established in order to reduce the emission of dioxins in the past two...
Sat, 10/19/2019 - 03:40
Author(s): Kailun Yu, Zengli YuAbstract2,3,7,8-Tetrachlorobenze-p-dioxin (TCDD), one of representive Endocrine Disrupting Chemicals (EDCs), has potential adverse effects on human health. Direct exposure to TCDD has been implicated in ovarian follicles development and functions deficits in adulthood. However, it is rarely reported whether indirect exposure to TCDD can cause similar negative impact...
Fri, 10/18/2019 - 03:39
Author(s): Annette Petersen, Bodil Hamborg Jensen, Nathalie Michelle Löbl, Elsa Nielsen, Lea Bredsdorff, Sisse Fagt, Tue Christensen, Julie BobergAbstractThis study shows that dietary habits have an impact on contaminant exposures. A tool was developed to calculate chemical exposures for different Danish population groups. First, the tool divided the individuals into quartiles using a previously...
Fri, 10/18/2019 - 03:29
The Aryl Hydrocarbon Receptor (AhR) is a transcription factor that, when activated by ligand-binding, has been shown to regulate the immune response. Pertussis Toxin (PTX) is a virulence factor found in Bordetella pertussis, a human respiratory pathogen that causes whooping cough. PTX promotes colonization and disease promotion by triggering a heightened inflammatory response. The role of AhR in...
Tue, 10/15/2019 - 03:34
Aflatoxins (AFs) as potent food contaminants are highly detrimental to human and animal health. The production of such biological toxins is influenced by environmental factors including pollutants, such as dioxins. Here, we report the biological feedback of an active AF-producer strain of A. flavus upon in vitro exposure to the most toxic congener of dioxins, the 2,3,7,8-tetrachlorinated dibenzo-...
Sat, 10/05/2019 - 03:41
by Karina Orlowska, Sylwia Swigonska, Agnieszka Sadowska, Monika Ruszkowska, Anna Nynca, Tomasz Molcan, Agata Zmijewska, Renata E. Ciereszko 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is a toxic man-made chemical compound contaminating the environment and affecting human/animal health and reproduction. Intracellular TCDD action usually involves the activation of aryl hydrocarbon receptor (AhR)....
Sat, 09/28/2019 - 03:28
Author(s): Fang Du, Ting Zhao, Hong-Chen Ji, Ying-Biao Luo, Fen Wang, Guang-Hua Mao, Wei-Wei Feng, Yao Chen, Xiang-Yang Wu, Liu-Qing YangAbstractPolychlorinated biphenyls (PCBs) would do serious damage to multiple systems, while coplanar polychlorinated biphenyls, the most toxic member of the family, has been widely taken into consideration. In this study, ICR mice were fed with different doses...
Sun, 09/22/2019 - 03:22
The aryl hydrocarbon receptor (AHR) mediates 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced toxicity that can lead to chloracne in humans. A characteristic of chloracne, in contrast to acne vulgaris, is shrinkage or loss of sebaceous glands. Acne vulgaris, on the other hand, is often accompanied by excessive sebum production. Here, we examined the role of AHR in lipid synthesis in human...
Sat, 09/21/2019 - 03:32
Author(s): Shuang Song, Xin Zhou, Chenqi Guo, Haiyan Zhang, Tao Zeng, Yidong Xie, Jinsong Liu, Chaofei Zhu, Xingrong SunAbstractTypical thermal processes are common sources of polychlorinated, polybrominated and mixed polybrominated/chlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs, PBDD/Fs, and PBCDD/Fs); however, very few reports have investigated their coemission. To clarify the...
Sat, 09/21/2019 - 03:32
Author(s): Congcong Zhang, Xiaoxiu Li, Zhiguang ZhouAbstractThe mass concentrations, toxic equivalent quantity (TEQ) concentrations and congener profiles of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) in the stack flue gas and ambient air of municipal solid waste incinerator (MSWI) were monitored in this study to evaluate the levels, emission characteristics, seasonal variation...
Sat, 09/21/2019 - 03:31
Author(s): Nassim Zeinali, Ibukun Oluwoye, Mohammednoor Altarawneh, Bogdan Z. DlugogorskiAbstractPolychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) remain of particular concern owing to their extensive toxicity towards health and accumulation in the environment. Atmospheric oxidation (by ambient oxygen molecules) of this class of persistent environmental pollutants has little to...
Fri, 09/20/2019 - 03:32
Increasing interest in characterizing risk assessment uncertainty is highlighted by recent recommendations from the National Academy of Sciences. In this paper we demonstrate the utility of applying qualitative and quantitative methods for assessing uncertainty to enhance risk‐based decision‐making for 2,3,7,8‐tetrachlorodibenzo‐p‐dioxin. The approach involved deconstructing the reference dose (...
Fri, 09/20/2019 - 03:32
2,3,7,8‐tetrachlorodibenzo‐p‐dioxin (TCDD) is a well‐known environmental contaminant that produces a wide variety of adverse effects in humans. Catalpol, a major bioactive compound enriched in the dried root of Rehmannia glutinosa, is a major iridoid glycoside that alleviates bone loss. However, the detailed mechanisms underlying the effects of catalpol remain unclear. The present study evaluated...
Fri, 09/20/2019 - 03:31
One of the direct causes of biodiversity loss is environmental pollution resulting from the use of chemicals. Different kinds of chemicals, such as persistent organic pollutants and some heavy metals, can be endocrine disruptors, which act at low doses over a long period of time and have a negative effect on the reproductive and thyroid system in vertebrates worldwide. Research on the effects of...
Fri, 09/20/2019 - 03:30
Aryl hydrocarbon receptor (AhR) activation is associated with carcinogenicity of non-genotoxic AhR-activating carcinogens such as 2,3,7,8-tetrachlorodibenzodioxin (TCDD), and is often observed with drug candidate molecules in development and raises safety concerns. As downstream effectors of AhR signaling, the expression and activity of Cyp1a1 and Cyp1a2 genes are commonly monitored as evidence...
Sun, 08/25/2019 - 01:09
Publication date: Available online 14 August 2019 Environmental ResearchAuthor(s): Cheng Xu, Xiaoqi Su, Yang Xu, Siyu Ma, Weiwei Duan, Xuming MoAbstractStudies have shown that persistent organic pollutants (POPs) can have various health effects. However, little is known about the effects of multiple chemicals with possible common sources of exposure on walking speed, a proxy index reflecting...
Sun, 08/25/2019 - 01:09
Publication date: Available online 6 August 2019 Environmental ResearchAuthor(s): Alix F. Leblanc, Eléonore A. Attignon, Emilie Distel, Spyros P. Karakitsios, Dimosthenis A. Sarigiannis, Sylvie Bortoli, Robert Barouki, Xavier Coumoul, Martine Aggerbeck, Etienne B. BlancAbstractIndividuals as well as entire ecosystems are exposed to mixtures of Persistent Organic Pollutants (POPs). Previously, we...
Mon, 08/05/2019 - 01:05
Publication date: November 2019 Food and Chemical Toxicology, Volume 133Author(s): Grazia Barone, Arianna Storelli, Nicoletta C. Quaglia, Angela Dambrosio, Rita Garofalo, Roberta Chiumarulo, Maria M. StorelliAbstractIn order to investigate PCB and PCDD/F concentrations and potential human health risk a study has been conducted in meat samples (beef, pork, chicken and turkey) purchased from...
Mon, 08/05/2019 - 01:05
Publication date: Available online 29 July 2019 Food and Chemical ToxicologyAuthor(s): A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A.D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D.C. Liebler, D. O'Brien, A. Patel, T.M. Penning
Mon, 07/22/2019 - 01:04
Available online 20 July 2019 Author(s): Wilma Taverne-Veldhuizen, Ron Hoogenboom, Guillaume ten Dam, Rik Herbes, Pieternel LuningAbstractThe Rapid Alert System for Food and Feed (period 1999–2014) reported exceeding levels of dioxins (polychlorinated dibenzo-p-dioxinsand dibenzofurans (PCDD/Fs)) in palm oil by-products, such as palm fatty acid distillate (PFAD) and hydrogenated palm fatty acid...
Thu, 07/11/2019 - 01:06
Publication date: September 2019 Environmental Research, Volume 176Author(s): Martí Nadal, Francisco García, Marta Schuhmacher, José L. DomingoAbstractDuring the period 1996–1998, a hazardous waste incinerator (HWI) was built in Constantí (Tarragona County, Catalonia, Spain). Because of the potential adverse effects of toxic emissions, mainly metals and dioxins and furans, waste incinerators in...
Wed, 07/03/2019 - 00:00
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.9b03384
Mon, 06/10/2019 - 01:12
Publication date: Available online 8 June 2019 Food and Chemical ToxicologyAuthor(s): A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A.D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D.C. Liebler, D. O'Brien, A. Patel, T.M. Penning
Mon, 04/22/2019 - 01:13
Publication date: Available online 19 April 2019 Environmental ResearchAuthor(s): Andreas Tornevi, Johan Sommar, Panu Rantakokko, Agneta Åkesson, Carolina Donat-Vargas, Hannu Kiviranta, Olov Rolandsson, Lars Rylander, Maria Wennberg, Ingvar A. BergdahlAbstractBackgroundPersistent organic pollutants (POPs) have been associated with type 2 diabetes (T2D), but causality is uncertain.ObjectiveWithin...
Fri, 03/29/2019 - 01:11
Publication date: June 2019 Environmental Research, Volume 173Author(s): Martí Nadal, Montse Mari, Marta Schuhmacher, José L. DomingoAbstractThe concentrations of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) were analyzed in 40 plasma samples of individuals living in zones under potential influence of the emissions of a hazardous waste incinerator (HWI) (Tarragona County,...
Mon, 10/08/2018 - 01:12
Publication date: Available online 6 October 2018 Food and Chemical ToxicologyAuthor(s): Walkiria Levy, Karl-Werner Schramm, Florian Mertes, Bernhard Henkelmann, Martina Maywald, Peter Uciechowski, Alexander Loa, Johannes Haedrich, Ines Thiem, Henner Hollert, Roland Goerlich, Thorsten Bernsmann, Lothar RinkAbstractRecent European regulations have indicated the need for new bioanalytical screening...
Mon, 10/01/2018 - 00:00
Abstract β-propeller phytase-like sequences (BPP-like sequences) are widespread in the microbial world and have been found in the sequenced genomes of aquatic, soil, and plant bacteria. Exploring NCBI microbial genome database for putative genes encoding phytase, a BPP-like sequence from Sphingomonas wittichii RW-1 (Sequence ID: CP000699.1), known for its capacity of degrading...
Mon, 04/30/2018 - 09:51
Publication date: October 2018 , Volume 92 Author(s): Regina Klapper, Noelia Carballeda-Sangiao, Thomas Kuhn, Hannah Malene Jensen, Kurt Buchmann, Miguel Gonzalez-Muñoz, Horst Karl Canned liver is a highly valuable and healthy product from the important commercial fish species cod Gadus morhua. Due to high levels of contaminants such as dioxins and dioxin-like PCBs (...
Fri, 04/13/2018 - 03:00
Journal of Food Protection, Volume 81, Issue 5, Page 842-847, May 2018.
Fri, 11/17/2017 - 00:00
AbstractDifferences in risk perceptions of public health and food safety hazards in various poultry husbandry systems by various stakeholder groups, may affect the acceptability of those husbandry systems. Therefore, the objective was to gain insight into risk perceptions of citizens, poultry farmers, and poultry veterinarians regarding food safety and public health hazards in poultry husbandry...
Mon, 11/06/2017 - 12:13
Publication date: 15 April 2018 , Volume 245 Author(s): Vincent Vaccher, Philippe Marchand, Mélanie Picherot, Gaud Dervilly-Pinel, Elodie Lesquin, Aline Brosseaud, Anaïs Venisseau, Bruno Le Bizec During a national monitoring plan, a pork fat sample was declared non-compliant for the sum of dioxins and PCB-DL (EU regulation). The National Reference Laboratory together with...
Mon, 11/06/2017 - 08:19
Publication date: December 2017 Food and Chemical Toxicology, Volume 110 Author(s): Jessica Tressou, Nadia Ben Abdallah, Christelle Planche, Gaud Dervilly-Pinel, Pierre Sans, Erwan Engel, Isabelle Albert In this paper, exposure to Polychlorinated biphenyls (PCBs) related to bovine meat consumption is assessed based on multiples sources of data, namely data collected within the...
Mon, 09/18/2017 - 17:00
Rance Nault, Kelly A. Fader, Jack R. Harkema, Tim Zacharewski The aryl hydrocarbon receptor (AhR) is a highly conserved transcription factor that mediates a broad spectrum of species-, strain-, sex-, age-, tissue-, and cell-specific responses elicited structurally diverse ligands including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). Dose-dependent effects on liver-specific and sexually dimorphic...
Fri, 08/18/2017 - 17:00
Eiki Kimura, Ken-ichiro Kubo, Toshihiro Endo, Wenting Ling, Kazunori Nakajima, Masaki Kakeyama, Chiharu Tohyama The basic helix-loop-helix (bHLH) transcription factors exert multiple functions in mammalian cerebral cortex development. The aryl hydrocarbon receptor (AhR), a member of the bHLH-Per-Arnt-Sim subfamily, is a ligand-activated transcription factor reported to regulate nervous system...
Fri, 06/30/2017 - 17:00
Christiane Hammerschmidt-Kamper, Daniel Biljes, Katja Merches, Irina Steiner, Thomas Daldrup, Marianne Bol-Schoenmakers, Raymond H. H. Pieters, Charlotte Esser In general, dietary antigens are tolerated the gut associated immune system. Impairment of this so-called oral tolerance is a serious health risk. We have previously shown that activation of the ligand-dependent transcription factor aryl...
Fri, 03/10/2017 - 00:00
Abstract The purpose of this study was to investigate the levels of polycyclic aromatic hydrocarbons [benzo(a)anthracene, chrysene, benzo(b)fluoranthene, and benzo(a)pyrene], polychlorinated biphenyls (6 marker and 12 dioxin-like), pesticides (74 compounds) and heavy metals (Pb, Cd, As, Hg, Fe, Cu), in the cold-pressed rapeseed oils from conventional (RC) and ecological...
Fri, 03/03/2017 - 06:20
Abstract This study investigated microbial population shifts on citrus carpoplane and the impact of irrigation and packhouse processing water in four commercial farms. Samples included oranges (n = 450) and water (n = 230). Mean microbial concentrations ranging from 1.6 to 3.6 log colony forming units (CFU)/cm2 were detected on unwashed fruit and were reduced at least by 2.0 log CFU/cm2 for...
Thu, 12/15/2016 - 11:00
Several bacteria use the plant hormone indole-3-acetic acid (IAA) as a sole carbon and energy source. A cluster of genes (named iac) encoding IAA degradation has been reported in Pseudomonas putida 1290, but the functions of these genes are not completely understood. The plant-growth-promoting rhizobacterium Paraburkholderia phytofirmans PsJN harbors iac gene homologues in its genome, but with a...

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