Heavy Metals

<< Return to all publications

Mon, 10/05/2020 - 04:02
The emergence and spread of multidrug resistant (MDR) pathogens with acquired resistance to almost all available antimicrobial agents has severely threatened the international healthcare community over the last two decades. The last resort antibiotic vancomycin is critical for treatment of several of these pathogens; howeverc vancomycin resistance is spreading due to the undesired accumulation of...
Sat, 10/03/2020 - 02:03
Organic sorbents alter physicochemical soil properties and mitigate heavy metal (HM) bioavailability. However, some sorbents are labile and, therefore, introduce the risk of HM release into soil after mineralisation. Before field application, new stable organic sorbents such as woodchip biochar (BIO) and brown coal waste (BCW) need to be tested and compared with standard organic amendments like...
Fri, 10/02/2020 - 22:20
Cadmium (Cd) contamination in rice grain is common worldwide. This study investigated the effect of degree of milling (DM) on the reduction of Cd in cooked rice grain and porridge (rice‐to‐water ratios 1:1.6 and 1:10, respectively) and Cd in vitro bioaccessibility. Cd‐contaminated rice grains with DMs of 20%, 15%, and 0% were cooked and then subjected to successive digestion in a gastrointestinal...
Fri, 10/02/2020 - 22:18
With metabolism being one of the main routes of drug elimination from the body (accounting for removal of around 75% of known drugs), it is crucial to understand and study metabolic stability of drug candidates. Metabolically unstable compounds are uncomfortable to administer (requiring repetitive dosage during therapy), while overly‐stable drugs increase risk of adverse drug reactions....
Fri, 10/02/2020 - 00:00
Multidrug-resistant pathogens pose a serious threat to human health. For decades, the antibiotic vancomycin has been a potent option when treating Gram-positive multidrug-resistant infections. Nonetheless, in recent decades, we have begun to see an increase in vancomycin-resistant bacteria. Here, we show that the nuclear factor-kappa B (NF-&kappa;B) inhibitor N-[3,5-Bis(trifluoromethyl)phenyl...
Thu, 10/01/2020 - 10:09
ABSTRACT The inaugural Black In Microbiology Week (#BlackInMicro) is 28 September 2020 through 4 October 2020. Its mission is to "showcase the presence and accomplishments of Black microbiologists from around the globe, connect Black microbiologists with one another and foster a sense of community among them, and provide a forum for the discussion of racial disparities in microbiology and its...
Wed, 09/30/2020 - 08:03
by Peng-Hu Liu, Zai-Xing Huang, Xu-Hui Luo, Hua Chen, Bo-Qi Weng, Yi-Xiang Wang, Li-Song Chen Cadmium (Cd) is a toxic metal occurring in the environment naturally. Almond mushroom (Agaricus brasiliensis) is a well-known cultivated edible and medicinal mushroom. In the past few decades, Cd accumulation in A.brasiliensis has received increasing attention. However, the molecular mechanisms of Cd-...
Tue, 09/29/2020 - 08:04
by Laura Ware Adlington, Markus Ritter, Nadine Schibille A large assemblage (n = 307) of architectural glasses (tesserae and windows) from the early 8th-century Umayyad residential site at Khirbat al-Minya was analysed by laser ablation inductively coupled plasma mass spectrometry. Trace element patterns are essential to establish the provenance of the base glass, while the comparative evaluation...
Tue, 09/29/2020 - 02:03
In this work was studied the single-component and multi-component abatement of metals in water using a hydrogel based on chitosan. The maximum single-component abatement capacities of cadmium (Cd) and lead (Pb) were 234.84 and 482.83 mg of metal per g of dried hydrogel at pH 6 and 40 °C, according to the Sips isotherm. The value for iron (Fe) was 386.59 mg g−1 at pH 4 and 40 °C, according to the...
Tue, 09/29/2020 - 02:03
Particulate matter (PM) is a complex mixture of particles that changes over time and from place to place; however, most PM is caused by the fuel combustion of motor vehicles and industry. PM is associated with acute and chronic illnesses, such as pulmonary and cardiovascular diseases. Medellín is one of the most polluted cities in Latin America. Therefore, the physicochemical characterization of...
Mon, 09/28/2020 - 02:05
In present study kinetic, thermal and rheological characteristics of oil isolated from flaxseed were studied and because of high content of α-linolenic acid (essential omega-3 fatty acid), flaxseed oil was incorporated in muffins by replacing fat/shortening at different levels (10%, 20%, 30% and 40%). To evaluate rheological behaviour, the experimental data of flow behaviour for flaxseed oil was...
Sun, 09/27/2020 - 04:02
Fungi have been proved as promising and prolific sources of functional secondary metabolites with potent agricultural applications. In this study, 14 xanthone derivatives (1–14), including six new ones, versicones I–N (1–4, 7, 11), and a biogenetically related derivative (15), were isolated from the alga-derived fungus Aspergillus versicolor D5. Their structures were elucidated by comprehensive...
Sat, 09/26/2020 - 02:03
Nano zerovalent iron (nZVI) is one of the most widely used nanotechnologies in soil remediation, but its long-term performance can be limited due to its high reactivity and rapid ageing. The aim of this study was to compare the immobilisation of Cd, Cu, Ni, and Pb in artificially contaminated soil samples using nZVI and to evaluate their retention over a 1-year period. Single-metal-contaminated...
Fri, 09/25/2020 - 02:05
The current study focuses on the tolerance of a strain of Halobacterium salinarum isolated from Sfax solar saltern (Tunisia) towards cadmium (Cd), lead (Pb), nickel (Ni), zinc (Zn), and copper (Cu) by using agar dilution methods in complex and minimal media. The results showed the least inhibitory metals based on Minimum Inhibitory Concentrations (MICs) were lead (MIC = 4.5 mM), cadmium (MIC = 4 ...
Fri, 09/25/2020 - 02:04
This study was conducted to determine the concentrations of trace elements, their sources, and human health risks associated with arsenic contamination in groundwater of the Niğde Municipality, south-central Turkey. Fourteen groundwater samples were collected from groundwater supply sources fed by the Niğde water distribution system and were analysed for Al, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se,...
Thu, 09/24/2020 - 06:23
Author(s): Yong Wang, Hongwei Chen, Weihua Chang, Rong Chen, Shiwen Xu, Dayong Tao The aim of the study was to investigate the protective effects of selenium yeast (SeY) against necroptosis triggered by Cd via inhibition of oxidative stress and MAPK pathway in the liver of chicken. Two hundred 120-day-old layers were randomly divided into four groups and raised for 120 days. The histopathological...
Thu, 09/24/2020 - 06:23
Author(s): Qirui An, Xiaolan He, Na Zheng, Shengnan Hou, Siyu Sun, Sujing Wang, Penyang Li, Xiaoqian Li, Xue Song The exposure to combinations of heavy metals can affect the genes of vegetables and heavy metals would accumulate in vegetables and thereby indirectly affecting human health. Exploring the links between genetic changes and phenotypic changes of carrot under the combined pollution of...
Thu, 09/24/2020 - 02:03
Hydroxyapatite-silica fibers were prepared by sol-gel process and electrospinning, and their capacity for adsorption of cadmium and lead ions in aqueous solution was studied. The samples were characterized by SEM, FTIR, TGA, DSC, BET, and XRD. The composite consists on a network of continuous rough fibers with mean diameter of 150 ± 40 nm after thermal treatment. The fibers present a mesoporous...
Wed, 09/23/2020 - 08:03
The Flint water crisis raised questions about the factors resulting in unacceptable soluble lead concentrations in the city’s drinking water. Although water treatment strategies, failure to follow regulations, and unethical behavior were all factors, knowledge deficits at the intersection of several scientific fields also contributed to the crisis. Pursuit of...
Tue, 09/22/2020 - 22:17
Coronavirus disease‐19 (COVID‐19) is a new disease caused by SARS‐CoV‐2. Since the beginning of 2020, it has become one of the main challenges of our times, causing a high incidence of severe pneumonia, acute respiratory distress syndrome (ARDS), multiorgan failure and death1. At the root of COVID‐19 lies the sudden development of ‘cytokine storms’, hyper‐inflammatory responses involving the...
Tue, 09/22/2020 - 22:15
The objective of this study was to assess the effect of environmental cadmium exposure according to urinary cadmium concentration (U‐Cd) on noncancer mortality in a general Japanese population. We conducted a longitudinal study for 19 years in 2804 inhabitants (1107 men and 1697 women) in some cadmium nonpolluted regions in Japan. The participants were classified into quartiles based on U‐Cd (μg/...
Tue, 09/22/2020 - 10:02
The glycosylphosphatidylinositol anchor biosynthesis inhibitor gepinacin demonstrates broad-spectrum antifungal activity and negligible mammalian toxicity in culture but is metabolically labile. The stability and bioactivity of 39 analogs were tested in vitro to identify LCUT-8, a stabilized lead with increased potency and promising single-dose pharmacokinetics. Unfortunately, no antifungal...
Tue, 09/22/2020 - 10:02
Lactoferrin (LF) is an iron-binding glycoprotein with broad-spectrum antimicrobial activity. Previously, we discovered that LF synergistically enhanced the antifungal efficacy of amphotericin B (AMB) across a variety of yeast species and subsequently hypothesized that this synergy was enhanced by the presence of small peptides derived from the whole LF molecule. In this study, LF was digested...
Tue, 09/22/2020 - 02:04
Arsenic (As) and cadmium (Cd) are common soil pollutants whose opposing geochemical behaviors must be taken into account in the development of cost-effective, environmentally friendly remediation strategies. In this study, a pot experiment with lettuce and a field experiment with wheat were performed to examine the impacts of zeolite, biochar, MnO2, zero-valent iron (ZVI) individually and in...
Sat, 09/19/2020 - 06:28
Author(s): Nehal Kamal, Zhiwei Liu, Chen Qian, Juanzi Wu, Xiaoxian Zhong Environmental pollution with heavy metals becomes an issue of serious concern worldwide. Cadmium is considered one which adversely affects living organisms. Recently, the usage of endophytic bacteria to enhance the plant growth and phytoremediation of heavy metals contaminated sites is gaining great attention. The current...
Sat, 09/19/2020 - 00:00
The reassessment of known but neglected natural compounds is a vital strategy for providing novel lead structures urgently needed to overcome antimicrobial resistance. Scaffolds with resistance-breaking properties represent the most promising candidates for a successful translation into future therapeutics. Our study focuses on chelocardin, a member of the atypical tetracyclines, and its...
Fri, 09/18/2020 - 10:02
Ergot alkaloids are important specialized fungal metabolites that are used to make potent pharmaceuticals for neurological diseases and disorders. Lysergic acid (LA) and dihydrolysergic acid (DHLA) are desirable lead compounds for pharmaceutical semisynthesis but are typically transient intermediates in the ergot alkaloid and dihydroergot alkaloid pathways. Previous work with Neosartorya fumigata...
Fri, 09/18/2020 - 06:14
Author(s): Vijakhana Pilaisangsuree, Piyanuch Anuwan, Kanitha Supdensong, Pimpimon Lumpa, Anupan Kongbangkerd, Apinun Limmongkon Plants counteract Cd toxicity by activating cellular stress responses. The simultaneous exogenous application of methyl jasmonate (MeJA) and methyl-β-cyclodextrin (CD) before Cd exposure improved the response of Arachis hypogaea hairy root culture to the unfavourable...
Fri, 09/18/2020 - 06:13
Author(s): Antonio León-Vaz, Luis C. Romero, Cecilia Gotor, Rosa León, Javier Vigara Cadmium is one of the most common heavy metals in contaminated aquatic environments and one of the most toxic contaminants for phytoplankton. Nevertheless, there are not enough studies focused on the effect of this metal in algae. Through a proteomic approach, this work shows how Cd can alter the growth, cell...
Fri, 09/18/2020 - 06:13
Author(s): Pengwei Yao, Hanjun Zhou, Xueli Li, Lin Wei, Jing Wang, Sheng Zhang, Xiefeng Ye Cadmium (Cd) easily accumulates in tobacco, which endangers public health through Cd exposure from smoking. However, its uptake, translocation, and distribution in tobacco plants during plant development or its response to biochar application are poorly understood. A pot experiment was conducted with...
Thu, 09/17/2020 - 22:17
Cadmium (Cd) is a common toxic heavy metal in the environment, and bacteria have evolved different strategies against Cd‐toxicity. Here we found that marine bacterium Bacillus sp. 98 could significantly alleviate Cd‐toxicity by recruiting calcium (Ca) for reducing excessive intracellular nitric oxide (NO) and enhancing iron acquisition. To investigate the underlying mechanisms, mass spectrometry‐...
Thu, 09/17/2020 - 16:00
Salicornia ramosissima is a C3 halophyte that grows naturally in South Western Spain salt marshes, under soil salinity and heavy metal pollution (mostly Cu, Zn, As, and Pb) caused by both natural and anthropogenic pressure. However, very few works have reported the phytoremediation potential of S. ramosissima. In this work, we studied a microbe-assisted phytoremediation strategy under greenhouse...
Thu, 09/17/2020 - 06:21
Author(s): Xiao-long Hou, Hang Han, Mulualem Tigabu, Qi-yan Li, Zong-xun Li, Chen-lu Zhu, Si-qi Huang, Li-ping Cai, Ai-qin Liu Pogonatherum crinitum is a promising lead (Pb) hyperaccumulator; however, the effects of Pb contamination on P. crinitum rhizosphere soil enzymatic activities and microbial composition remain largely unexplored. Thus, an indoor experiment was conducted by cultivating P....
Thu, 09/17/2020 - 00:00
The mechanism of aluminum toxicity was studied in the model cells of Saccharomyces cerevisiae. Cell growth of yeast was inhibited by aluminum. The spot assay showed that the mechanism of aluminum detoxification in yeast cells was different from that of heavy metal cadmium. After treatment with aluminum, intracellular levels of reactive oxygen species, protein carbonyl, and thiobarbituric acid...
Wed, 09/16/2020 - 16:00
Lentinula edodes, also known as Xiang’gu, is commonly eaten in cultures around the world. However, L. edodes is particularly susceptible to enrichment with heavy metals, particularly cadmium (Cd), which is toxic to human health. Understanding the molecular mechanism and mining key genes involved in Cd enrichment will facilitate genetic modification of L. edodes strains. Two L. edodes genotypes,...
Wed, 09/16/2020 - 12:01
Inorganic arsenic (iAs) is a recognized environment-related factor for bladder cancer (BCa). Arsenic (+3 oxidation state) methyltransferase (AS3MT) gene might influence BCa by regulating iAs metabolism. The aim of the present study was to explore whether AS3MT polymorphisms could affect BCa susceptibility. We systematically reviewed eligible case-control studies about AS3MT polymorphisms and BCa...
Wed, 09/16/2020 - 12:01
Drug-induced liver injury is a major reason for drug candidate attrition from development, denied commercialization, market withdrawal, and restricted prescribing of pharmaceuticals. The metabolic bioactivation of drugs to chemically reactive metabolites (CRMs) contribute to liver-associated adverse drug reactions in humans that often goes undetected in conventional animal toxicology studies. A...
Wed, 09/16/2020 - 12:01
Cadmium (Cd) is a heavy metal and an environmental pollutant. However, the full spectrum of its neurotoxicity and the underlying mechanisms are not completely understood. Our previous studies demonstrated that Cd exposure impairs adult hippocampal neurogenesis and hippocampus-dependent memory in mice. This study aims to determine if these adverse effects of Cd exposure can be mitigated by...
Wed, 09/16/2020 - 00:01
Heavy metals are typical cumulative pollutants that can enter and poison the human body through the food chain. However, the molecular mechanism of heavy metal-induced oxidative stress is unclear. In this study, we characterize PvKelch-like-1 from P. vannamei and explore its antioxidant roles in immune regulation of crustaceans. PvKelch-like-1 full length contains 2107 nucleotides, consists of a...
Tue, 09/15/2020 - 16:01
Lead–zinc (Pb–Zn) mine tailings pose a great risk to the natural environment and human health because of their high toxicity. In this study, the responses of photosynthesis, chlorophyll fluorescence, and antioxidative enzyme of Melia azedarach and Ligustrum lucidum in the soil contaminated by Pb–Zn mine tailings were investigated. Results showed that Pb–Zn mine tailings significantly reduced net...
Tue, 09/15/2020 - 02:03
Abstract Aims This research aimed to establish how Hordeum vulgare responds to abiotic and biotic stress affecting in tandem. Methods Plants were inoculated with Heterodera filipjevi and treated with cadmium (Cd) concentration (5 μM) that can occur in the cultivated soil. To verify the hypothesis about participation of increased antioxidative defence in H. vulgare under stress, biochemical and...
Tue, 09/15/2020 - 00:00
Bitis arietans is a snake of medical importance, as it is responsible for more accidents in humans and domestic animals than all other African snakes put together. The accidents are characterized by local and systemic alterations, such as inflammation, cardiovascular and hemostatic disturbances, which can lead victims to death or permanent disability. However, little is known about the...
Sat, 09/12/2020 - 08:04
by Taylor R. Nicholas, Jingwei Meng, Benjamin M. Greulich, Teresa Stevie Morris, Peter C. Hollenhorst Aberrant expression of the transcription factor ERG is a key driving event in approximately one-half of all of prostate cancers. Lacking an enzymatic pocket and mainly disordered, the structure of ERG is difficult to exploit for therapeutic design. We recently identified EWS as a specific...
Sat, 09/12/2020 - 06:20
Author(s): Guobing Wang, Qingquan Zhang, Wenchao Du, Renzhang Lin, Jiahua Li, Fuxun Ai, Ying Yin, Rong Ji, Xiaorong Wang, Hongyan Guo In-situ immobilization is an effective and economically viable strategy for remediation of soil extensively polluted with heavy metals. The long-term sustainability is critical for the remediation practice. In the present study, a ten-year experiment was performed...
Fri, 09/11/2020 - 22:21
Priority pollutants chlorophenols are broadly used chemicals that are persistent in the environment and causing serious human health hazards. The current study introduces a novel adsorbent for the extraction of chlorophenols from river water, surface water, and milk by headspace solid phase microextraction coupled with GC. The adsorbent composite was prepared by blending polycaprolactam (nylon‐6...
Fri, 09/11/2020 - 18:03
Some snails (Achatina spp) can be used as a biosensor of heavy metal poisoning. This study thus estimated some heavy metal levels, antioxidant markers, and lipid profiles of snails handpicked around cement factory vicinities in Ogun State, Nigeria. Snails and soil samples were collected from Oke, Ewekoro, Papalanto, and Mowodani Imeko-Afon (control site). Lead (Pb), cadmium (Cd), and arsenic (As...
Thu, 09/10/2020 - 22:19
Variation in inter‐human attractiveness to mosquitoes, and the preference of mosquitoes to bite certain regions on the human host, are possible avenues for identifying lead compounds as potential mosquito attractants or repellents. We report a practical, non‐invasive method for the separation and detection of skin surface chemical compounds and comparison of skin chemical profiles between the...
Thu, 09/10/2020 - 06:19
Author(s): Xianlei Jiang, Xupeng Xing, Yingbing Zhang, Chengtu Zhang, Ying Wu, Yongzhong Chen, Ru Meng, Huiqun Jia, Yuyao Cheng, Yong Zhang, Jianmin Su Lead, a common metallic contaminant, is widespread in the living environment, and has deleterious effects on the reproductive systems of humans and animals. Although numerous toxic effects of lead have been reported, the effects and underlying...
Wed, 09/09/2020 - 06:13
Author(s): Pingjie Fu, Wei Zhang, Keming Yang, Fei Meng Monitoring heavy metal stress in crops via hyperspectral remote sensing technology is an effective way. A new approach, namely the ratio difference of autocorrelation function first derivative (RDA), is proposed to extract characteristic regions of maize leaves spectra for the initially identification on contaminated category of copper (Cu)...
Tue, 09/08/2020 - 22:24
The Strategic Alliance for Research into Infectious Diseases of Animals and Zoonoses (STAR‐IDAZ) International Research Consortium (IRC) coordinates global animal health research to accelerate delivery of disease control tools and strategies. With this vision, STAR‐IDAZ IRC has constructed four generic research roadmaps for the development of candidate vaccines, diagnostic tests, therapeutics and...

Pages