Heavy Metals

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Wed, 09/02/2020 - 06:15
Author(s): Zhiyun Zhang, Helen Lin, Chuanxin Ma, Lingzi Zhang, Julia Zelevinsky, Ming Xia, Yuecheng Xu, Jason C. White, Julian Tyson, Lili He Inorganic arsenic (iAs) in foods has raised significant concerns because it is carcinogenic to human beings. Herein, we integrated the Gutzeit method with X-ray fluorescence (XRF) spectroscopy to measure iAs in selected beverages within 45 min. Briefly, iAs...
Wed, 09/02/2020 - 04:02
Lead (Pb) is an important pollutant of worldwide concern with respect to extensive pollution sources and highly toxic effect. Flavonol can improve plant resistance to abiotic stress and is also responsible for the alleviating effect under Pb stress. The relationship between Pb stress and flavonol and the knowledge about the mechanisms of flavonol function are very limited. Pb affected the energy...
Wed, 09/02/2020 - 02:03
The negative impacts of road salt (primarily NaCl) on freshwater ecosystems and ground and surface waters used for drinking purposes have been extensively documented. Besides direct increases in chloride (Cl−) and sodium (Na+) concentrations in receiving waters, these ions are responsible for a myriad of soil chemical changes and processes resulting in increased corrosivity of water and...
Wed, 09/02/2020 - 02:03
Currently, no specific drug and vaccine are available for the new coronavirus SARS-CoV-2, and nutritional supplementation should be helpful. This study tried to provide reference for protein supplementation. Specifically, in silico method was employed to simulate protein degradation by gastrointestinal enzymes and to produce a large number of active peptides, then, the binding ability of these...
Tue, 09/01/2020 - 22:25
Sub‐seasonal streamflow forecasts, with lead times of 1‐30 days, provide valuable information for operational water resource management. This paper introduces the Multi‐Temporal Hydrological Residual Error model (MuTHRE) to address the challenge of obtaining “seamless” sub‐seasonal forecasts, i.e., daily forecasts with consistent high‐quality performance over multiple lead times (1‐30 days) and...
Tue, 09/01/2020 - 22:25
China has experienced a sudden multi‐focal and multi‐round of African swine fever (ASF) outbreaks during 2018. The subsequent epidemiological survey resulted in a debate including the possibility of a transboundary spread from European Russia to China through wild boar. We contribute to the debate by assessing a hypothetical overland Euro‐Siberian transmission path and its associated ASF arrival...
Tue, 09/01/2020 - 22:16
Aims To identify the bacteria nodulating Sulla spinosissima growing profusely in a lead and zinc mine tailings in Eastern Morocco. Methods and Results Thirty two rhizobial cultures, isolated from root nodules of S. spinosissima growing in soils of the mining site, were tolerant to different heavy metals. The ERIC‐PCR fingerprinting analysis clustered the isolates into 7 different groups, and the...
Tue, 09/01/2020 - 22:14
BACKGROUND The manila clam Ruditapes philippinarum and the wedge clam Donax trunculus are economic bivalve species which constitute an important part of the natural bivalve beds in the Marmara Sea, Turkey. Toxic chemicals such as, dioxins, dioxin‐like polychlorinated biphenyls (PCBs), polycyclic hydrocarbons (PAHs), and toxic metals are recognized as important health risk factors that threaten...
Tue, 09/01/2020 - 06:26
Author(s): Tingting Fu, Ruiying Zhao, Bifeng Hu, Xiaolin Jia, Zhige Wang, Lianqing Zhou, Mingxiang Huang, Yan Li, Zhou Shi Modelling the mass balance and forecasting the temporal variations of cadmium (Cd) in farmland soil play a critical role in the development of mitigation strategies for Cd pollution. In this study, a novel framework integrating the mass balance model with model-independent...
Tue, 09/01/2020 - 02:04
Metals occur naturally in the environment; however, anthropogenic practices have greatly increased metal concentrations in waterways, sediments, and biota. Metals pose health risks to marine organisms and have been associated with oxidative stress, which can lead to protein denaturation, DNA mutations, and cellular apoptosis. Sharks are important species ecologically, recreationally, and...
Tue, 09/01/2020 - 02:02
In order to find the best nanometal oxides to alleviate the cadmium-caused toxicity, we chose five kinds of nanometal oxides (MgO NPs, ZnO NPs, α-Fe2O3 NPs, γ-Fe2O3 NPs, and Fe3O4 NPs) tried to research the different effects. In this study, the effects of nanometal oxides on physiological response indicators in wheat seedlings poisoned by cadmium were figured out. The results showed that the...
Sat, 08/29/2020 - 18:03
This study investigated whether the mechanism underlying the neurotoxic effects of cadmium chloride (CdCl2) in rats involves p66Shc. This study comprised an initial in vivo experiment followed by an in vitro experiment. For the in vivo experiment, male rats were orally administered saline (vehicle) or CdCl2 (0.05 mg/kg) for 30 days. Thereafter, spatial and retention memory of rats were tested and...
Sat, 08/29/2020 - 04:02
Infections caused by drug-resistant pathogens are a worldwide challenge for public health. Antimicrobial peptides (AMPs) are regarded as promising antibiotic alternatives for the treatment of drug-resistant infections. In the present study, a series of small peptides were designed based on our previously reported sea snake AMP Hc-CATH. From them, the lead peptide HC1-D2, a truncated peptide...
Fri, 08/28/2020 - 06:13
Author(s): Balachander Rakesh, Bhavani Shankara Bagepally, Ravibabu Kalahasthi, Madhumitha Haridoss Present study aimed to systematically review and synthesise quantitative evidence on association between occupational Lead (Pb) exposure and male reproductive hormones (MRH) and sperm quality from the existing literature. Observational studies investigating the effects of Pb exposure on MRH, sperm-...
Thu, 08/27/2020 - 08:05
by Jihyun An, Ha Il Kim, Seheon Chang, Ju Hyun Shim Backgrounds and aims Because of the known limitations of ultrasonography (US) alone, we re-evaluated whether complimentary testing for serum alpha-fetoprotein (AFP) is helpful in surveilling for hepatocellular carcinoma (HCC) in high-risk populations. Methods We included, from a hospital-based cancer registry, 1,776 asymptomatic adults who were...
Wed, 08/26/2020 - 16:00
Candida albicans is the most common cause of fungal infection. The emergence of drug resistance leads to the need for novel antifungal agents. We aimed to design naphthofuranquinone analogs to treat drug-resistant C. albicans for topical application on cutaneous candidiasis. The time-killing response, agar diffusion, and live/dead assay of the antifungal activity were estimated against 5-...
Wed, 08/26/2020 - 02:03
Ground venison packets from shotgun- and archery-harvested White-tailed Deer in Illinois in 2013 and 2014 were analyzed for metal contamination. Radiographs indicated that 48% of 27 ground venison packets from 10 shotgun-harvested deer contained metal fragments, while none of the 15 packets from three archery-harvested deer contained fragments. ICP-MS analysis verified that all metal fragments...
Tue, 08/25/2020 - 10:05
ABSTRACT Cryptococcus neoformans (Cn) is the leading cause of fungal meningitis, a deadly disease with limited therapeutic options. Dissemination to the central nervous system hinges on the ability of Cn to breach the blood-brain barrier (BBB) and is considered an attribute of Cn virulence. Targeting virulence instead of growth for antifungal drug development has not been fully exploited despite...
Mon, 08/24/2020 - 06:12
Author(s): Lijuan Sun, Xueying Cao, Changyin Tan, Yueqiang Deng, Runzhong Cai, Xi Peng, Jia Bai Root exudates are the most direct manifestation of the response of plants changes in the external environment. Therefore, based on non-targeted gas chromatography-time-of-flight mass spectrometry and metabolomics, the response of Sedum plumbizincicola root exudates to Cd stress was used to reveal the...
Mon, 08/24/2020 - 06:12
Author(s): Jing-Fang Cai, Li Zhang, Yu Zhang, Ming-Xiang Zhang, Hong-Li Li, Hui-Juan Xia, Wei-Jing Kong, Fei-Hai Yu Following oil extraction in the wetland of the Yellow River Delta, heavy metal contamination of coastal saline-alkaline soil, especially with cadmium (Cd), has become a serious environmental problem in some regions. Biochar application has been proposed to remedy Cd-contaminated...
Sun, 08/23/2020 - 06:12
Author(s): Zhihua Xiao, Dongsheng Zou, Xinyi Zeng, Liqing Zhang, Fen Liu, Andong Wang, Qingru Zeng, Guolin Zhang, Longcheng Li The mechanisms of intercropping increasing plant biomass, cadmium accumulation, and organic acids secreted in rhizosphere soil are still unclear. Oilseed rape and intercrops were grown in boxes separated either with no barrier between the compartments or by a nylon mesh...
Sun, 08/23/2020 - 06:12
Author(s): Haofei Gong, Jie Chi, Zheng Ding, Fan Zhang, Jianjun Huang Due to high sorption capacity for heavy metals, magnetic biochar (MBC) has the potential to adsorb heavy metals in soils, which are then removed together with MBC from soils by a magnetic field. In this study, two magnetic biochars (MBC300 and MBC700) were derived from the magnetization of wheat straw biochars pyrolyzed at 300...
Sat, 08/22/2020 - 06:21
Author(s): Stephen N. Morgan, Nicole M. Mason, Mywish K. Maredia Encouraging the widespread adoption and use of new on-farm technologies is an important part of productivity-led strategies to promote agricultural transformation. While many interventions have been designed to promote adoption through extension and education, little is known about how these efforts influence farmer willingness-to-...
Sat, 08/22/2020 - 06:18
Author(s): Chang Wang, Gaohui Nie, Yu Zhuang, Ruiming Hu, Huansheng Wu, Chenghong Xing, Guyue Li, Guoliang Hu, Fan Yang, Caiying Zhang Increasing evidence indicates autophagy and apoptosis are involved in the toxicity mechanism of heavy metals. Our previous studies showed that cadmium (Cd) could induce autophagy and apoptosis in duck kidneys in vivo, nevertheless, the interaction between them has...
Fri, 08/21/2020 - 18:02
Metallothioneins (MTs) are low molecular weight cysteine-rich, metal-binding proteins. They are involved in transportation and detoxification of heavy metals, homeostasis of essential metals, and as antioxidation against reactive oxygen species. Polymorphisms in a gene may increase or decrease the expression efficiency of a gene. This study aimed to determine the genetic effect of MT1A rs8052394...
Fri, 08/21/2020 - 10:03
Widespread resistance against antimalarial drugs thwarts current efforts for controlling the disease and urges the discovery of new effective treatments. Drug repositioning is increasingly becoming an attractive strategy since it can reduce costs, risks, and time-to-market. Herein, we have used this strategy to identify novel antimalarial hits. We used a comparative in silico chemogenomics...
Fri, 08/21/2020 - 10:03
The incidence of invasive fungal infections is rising due to the increase in susceptible populations. Current clinically available drugs have therapeutic limitations due to toxicity, a narrow spectrum of activity, and, more importantly, the consistent rise of fungal species that are intrinsically resistant or that develop resistance due to prolonged therapy. Thus, there is an urgent need for new...
Fri, 08/21/2020 - 06:12
Author(s): Jian Yang, Tianyi Guo, Xiao Liang, Yuanfang Zhai, Yikun Cheng, Hui Sun, Yongping Cui, Xiaolong Cheng Cadmium (Cd) exposure in environment is associated with development of esophageal cancer. However, the mechanisms of Cd-induced carcinogenesis are still not been fully cleared, and the present study aimed to explore the possible etiological mechanism of Cd-induced esophageal cancer....
Fri, 08/21/2020 - 06:12
Author(s): Snehalata Majumdar, Sonal Sachdev, Rita Kundu Contamination of agricultural fields with Cadmium (Cd) due to several agricultural practices is increasing worldwide. The rice plants can easily take up Cd and accumulate it into different parts, including the grains, posing a threat to human health even at low concentration exposure. Several phytohormones, including Salicylic acid (SA)...
Fri, 08/21/2020 - 04:02
Praziquantel is the only widely available drug to treat schistosomiasis. With very few candidates currently in the drug development pipeline, there is an urgent need to discover and develop novel antischistosomal drugs. In this regard, the pyrido[1,2-a]benzimidazole (PBI) scaffold has emerged as a promising chemotype in hit-to-lead efforts. Here, we report a novel series of antischistosomal PBIs...
Fri, 08/21/2020 - 04:02
The clinical effectiveness of the important β-lactam class of antibiotics is under threat by the emergence of resistance, mostly due to the production of acquired serine- (SBL) and metallo-β-lactamase (MBL) enzymes. To address this resistance issue, multiple β-lactam/β-lactamase inhibitor combinations have been successfully introduced into the clinic over the past several decades. However, all of...
Fri, 08/21/2020 - 02:02
Abstract Aims Lead is a hazardous heavy metal pollutant present in the environment, and iron is an essential micronutrient with numerous cellular functions in normal physiology. However few studies have focused on the influence and interaction of lead and iron changes during plant growth. So the present study investigated the mechanism how lead and iron affected in upland rice (Oryza sativa L.)...
Thu, 08/20/2020 - 22:21
Myxoma virus (MYXV) is the aetiological agent of myxomatosis, a systemic, mostly lethal disease that affects European rabbits. Vaccination against it, although widespread, has not been completely effective and disease outbreaks still take place on farms which carry out vaccination programmes. Since some of these cases have been attributed to airborne transmission or the spread of the virus via...
Thu, 08/20/2020 - 22:16
Heavy metal is one of the major factors threatening the survival of microorganisms. Here, a deep‐sea bacterium designated Idiomarina sp. OT37‐5b possessing strong cadmium (Cd) tolerance was isolated from a typical hydrothermal vent. Both Cd‐resistance and removal efficiency of Idiomarina sp. OT37‐5b were significantly promoted by the supplement of cysteine and meanwhile large amount of CdS...
Thu, 08/20/2020 - 18:03
Because of the numerous industrial applications of lead (Pb), Pb poisoning is an important public health threat in the world particularly in developing and industrialized countries. Oxidative stress is one of the important mechanisms of Pb-mediated toxicity. Deferoxamine (DFO) is an iron chelating agent that has recently shown antioxidant and antiapoptotic effects. This study investigated the...
Thu, 08/20/2020 - 12:01
Background Children incur lead toxicity even at low blood-lead concentrations (BLCs), and testing in England is opportunistic. We described epidemiology of cases notified to a passive laboratory-based surveillance system (SS), the Lead Poisoning in Children (LPIC) SS to inform opportunities to prevent lead exposure in children in England. Methods Surveillance population: children <16 years of...
Thu, 08/20/2020 - 10:04
This study presents high-quality draft genome assemblies of six bacterial strains isolated from the roots of wheat grown in soil contaminated with cadmium. The results of this study will help to elucidate at the molecular level how heavy metals affect interactions between beneficial rhizobacteria and crop plants.
Wed, 08/19/2020 - 06:14
Author(s): Daowei Zhang, Fang Dong, Ya Zhang, Yanlan Huang, Chaofan Zhang Sweetpotato (Ipomoea batatas L.) possess great application prospects due to their low cadmium (Cd) concentration within their storage roots despite growth on Cd-polluted fields. The mechanisms of low Cd accumulation in storage root is not entirely clear. We found that the blocking effect of Cd uptake in the root absorption...
Tue, 08/18/2020 - 04:02
Cytotoxic frog antimicrobial peptide Temporin L (TempL) is an attractive molecule for the design of lead antimicrobial agents due to its short size and versatile biological activities. However, noncytotoxic TempL variants with desirable biological activities have rarely been reported. TempL analogue Q3K,TempL is water-soluble and possesses a significant antiendotoxin property along with...
Tue, 08/18/2020 - 02:04
Due to the increasing consumption of platinum (Pt), especially in automobile exhaust catalysts, environmental concentrations of Pt are of emerging concern worldwide. Limited information exists on environmental concentrations, particularly in Pt mining regions, while South Africa is the world’s main supplier of Pt. Moreover, other metals are also released as by-products of Pt mining, which might...
Tue, 08/18/2020 - 02:02
Abstract Aims Arbuscular mycorrhizal fungi (AMF) can enhance cadmium (Cd) tolerance and decrease Cd uptake of rice plant. However, in these processes, the essential role of reactive oxygen species (ROS)-antioxidants interactions is so far not investigated. Methods We inoculated AMF, Funneliformis mosseae (Fm) and Rhizophagus intraradices (Ri), to upland rice subjected to 0, 2 or 10 mg Cd kg−1...
Mon, 08/17/2020 - 06:17
Author(s): Pooja Chauhan, Savita Chaudhary, Rajeev Kumar The rapid growth in the industrial and urban sector has filled enormous stress on environment. The exponential use of chemicals especially metal ions has raised the pollution index and affected the health of living beings. Therefore, it is highly essential need to monitor and remove these metal ion toxins by the advanced materials which...
Sat, 08/15/2020 - 06:21
Author(s): E. Pogoson, M. Carey, C. Meharg, A.A. Meharg Cadmium, inorganic arsenic and, potentially, dimethyl arsenic acid are carcinogens widely elevated in rice. Here it was identified that the food-safe and common cadmium chelator citric acid efficiently removed cadmium from intact grain via pre-soaking procedure, while also reducing arsenic species. A twostep pre-soaking stage was developed...
Sat, 08/15/2020 - 06:18
Author(s): Qing Cao, Weijing Liu, Yurong Gu, Liqiang Xie, Weili Jiang, Yan Gao, Liuyan Yang Heavy metals and microcystins commonly co-exist in water bodies with cyanobacteria, and have been shown to affect aquatic plants. However, their combined effects remain largely unknown. In this study, the toxic effects of copper (Cu) and cadmium (Cd) on Ceratophyllum demersum L. were characterized in the...
Sat, 08/15/2020 - 02:04
A pot experiment was conducted to examine the effect of foliar application of various levels of ZnSO4 on wheat (Triticum aestivum L.) under cadmium (Cd) stress. Seeds of two wheat varieties i.e., Ujala-2016 and Anaj-2017 were sown in sand filled plastic pots. Cadmium (CdCl2) stress i.e., 0 and 0.5 mM CdCl2 was applied in full strength Hoagland’s nutrient solution after 4 weeks of seed germination...
Fri, 08/14/2020 - 16:00
To understand the roles of Malus rootstock, scion, and their interaction in Cd accumulation and tolerance, four scion/rootstock combinations consisting of the apple cultivars “Hanfu” (HF) and “Fuji” (FJ) grafted onto M. baccata (Mb) or M. micromalus “qingzhoulinqin” (Mm) rootstocks differing in relative Cd tolerance were exposed either to 0 µM or 50 µM CdCl2 for 18 d. Cd accumulation and...
Fri, 08/14/2020 - 08:02
by Ieong Siu, Julian Henderson, Dashu Qin, Yu Ding, Jianfeng Cui, Hongjiao Ma Seventeen glass vessels and twenty glass beads recovered from the excavations at the ancient city of Malindi and the archaeological site of Mambrui in Kenya, east Africa were analysed using electron probe microanalysis (EPMA) and laser ablation-inductively coupled plasma-mass spectrometry (LA-ICP-MS). The results show...
Fri, 08/14/2020 - 00:00
The deep ocean is the largest habitat for life on Earth, though the microorganisms that occupy this unique environmental niche remain largely unexplored. Due to the significant logistical and operational challenges associated with accessing the deep ocean, bioprospecting programmes that seek to generate novel products from marine organisms have, to date, focused predominantly on samples recovered...
Thu, 08/13/2020 - 22:21
Use of Real‐Time Control (RTC) technology in Rainwater Harvesting Systems (RWH) can improve performance across water supply, flood protection, and environmental flow provision. Such systems make the most of rainfall forecast information, to release water prior to storm events and thus minimise uncontrolled overflows. To date, most advanced applications have adopted 24‐hr forecast information,...
Thu, 08/13/2020 - 22:16
Widespread of heavy metals contamination has led to several environmental problems. Some biological methods to remove heavy metals from contaminated wastewater are being widely explored. In the present study, the efficiency of a white‐rot fungus, Phlebia brevispora to remove different metals (Pb, Cd and Ni) has been evaluated. Atomic absorption spectroscopy of treated and untreated metal...

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