Heavy Metals

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Mon, 12/26/2016 - 00:00
Spider venoms are a complex mixture of peptides with a large number of neurotoxins targeting ion channels. Although thousands of peptide toxins have been identified from venoms of numerous species of spiders, many unknown species urgently need to be investigated. In this study, a novel sodium channel inhibitor, µ-TRTX-Hl1a, was identified from the venom of Haplopelma lividum. It contained eight...
Sat, 12/24/2016 - 04:49
Publication date: Available online 22 December 2016 Food and Chemical Toxicology Author(s): Pablo Olmedo, Maria Grau-Perez, Amanda Fretts, Maria Tellez-Plaza, Fernando Gil, Fawn Yeh, Jason G. Umans, Kevin A. Francesconi, Walter Goessler, Nora Franceschini, Elisa T. Lee, Lyle G. Best, Shelley A. Cole, Barbara V. Howard, Ana Navas-Acien Urinary cadmium (Cd)...
Thu, 12/22/2016 - 05:41
Publication date: May 2017 , Volume 75 Author(s): Martin Wiech, Eirin Vik, Arne Duinker, Sylvia Frantzen, Snorre Bakke, Amund Maage Increased cadmium concentrations in claw meat were demonstrated after cooking and freezing practices of whole brown crabs. This was investigated in crabs from two different locations along the Norwegian coast, one with normal and one with high cadmium...
Wed, 12/21/2016 - 00:00
Abstract The biosynthesis of quantum dots has been explored as an alternative to traditional physicochemical methods; however, relatively few studies have determined optimal synthesis parameters. Saccharomyces cerevisiae sequentially treated with sodium selenite and cadmium chloride synthesized CdSe quantum dots in the cytoplasm. These nanoparticles displayed a prominent yellow...
Thu, 12/15/2016 - 16:34
Publication date: Available online 14 December 2016 Author(s): Natália C. Gaeta, Svetlana F. Lima, Andre G. Teixeira, Erika K. Ganda, Georgios Oikonomou, Lilian Gregory, Rodrigo C. Bicalho Bovine respiratory disease (BRD) is a multifactorial disorder responsible for severe economic losses in dairy and feedlot herds. Advances in next-generation sequencing mean that microbial...
Thu, 12/15/2016 - 11:00
The heavy metal cadmium is widely used and released into the environment, posing a severe threat to crops and humans. Saccharomyces cerevisiae is one of the most commonly used organisms in the investigation of environmental metal toxicity. We investigated cadmium stress and the adaptive mechanisms of yeast by screening a genome-wide essential gene overexpression library. A candidate gene, OLE1,...
Wed, 12/14/2016 - 17:00
Dongfeng Ning, Yongchao Liang, Zhandong Liu, Junfu Xiao, Aiwang Duan Slag-based silicate fertilizer has been widely used to improve soil silicon- availability and crop productivity. A consecutive early rice-late rice rotation experiment was conducted to test the impacts of steel slag on soil pH, silicon availability, rice growth and metals-immobilization in paddy soil. Our results show that...
Tue, 12/06/2016 - 00:00
Certain feedingstuffs are sources of contamination for animals with cadmium (Cd) and lead (Pb). Different approaches for sample digestion, performance assessment, and measurement uncertainty for the analysis of Pb and Cd by flame atomic absorption spectrometry were compared. Full method validation, including matrix effect and analytical limits, were assessed. Despite having a...
Thu, 12/01/2016 - 00:00
High-resolution inductively coupled plasma mass spectrometry (ICP-MS) was applied to determine potential toxic element pollution in rice and paddy soil in a lead-acid battery production area. The contamination levels of chromium (Cr), cadmium (Cd), and lead (Pb) in rice and soil at three sampling areas were determined, and the uptake mechanism of Cr, Cd, and Pb from soil to...
Tue, 11/22/2016 - 02:35
Publication date: Available online 21 November 2016 Author(s): Seok Hyeon Na, Hyejin Jeon, Yoo Jeong Kim, Hyo Il Kwon, Gati Noble Selasi, Asiimwe Nicholas, Chang-Soo Yun, Sang Ho Lee, Je Chul Lee The aim of this study was to screen lead compounds exhibiting potent in vitro antimicrobial activity against multidrug-resistant (MDR) Acinetobacter baumannii strains from a...
Mon, 11/21/2016 - 18:25
Summary Wide-spread abundance in soil and water, coupled with high toxicity have put arsenic at the top of the list of environmental contaminants. Early studies demonstrated that both concentration and the valence state of inorganic arsenic (arsenite, As(III) vs. arsenate As(V)) can be modulated by microbes. Using genetics, transcriptomic and proteomic techniques, microbe-arsenic detoxification,...
Sat, 11/12/2016 - 01:55
Abstract BACKGROUNDThe study aimed to verify whether the consumption of frozen fishery products was safe in terms of Cd and Pb content. The study material was 31 frozen fishery products (15 breaded products and 16 fillets). Immediately before the analyses the products were subject to culinary treatment according to the recommendations of the producer: fried in colza oil or baked in a gas oven....
Thu, 11/10/2016 - 08:21
Sinorhizobium sp. M14 is an As(III)-oxidizing, psychrotolerant strain, capable of growth in the presence of extremely high concentrations of arsenic and many other heavy metals. Metallotolerant abilities of the M14 strain depend upon the presence of two extrachromosomal replicons: pSinA (~ 109 kb) and pSinB (~ 300 kb). The latter was subjected to complex analysis. The performed analysis...
Thu, 11/10/2016 - 04:04
, Volume 106, Issue 12, Page e6-e6, December 2016.
Wed, 11/02/2016 - 02:02
Publication date: November 2016 , Volume 89, Part 1 Author(s): Fabiana Roberta Segura, Juliana Maria de Oliveira Souza, Eloísa Silva De Paula, Airton da Cunha Martins, Ana Carolina Cavalheiro Paulelli, Fernando Barbosa, Bruno Lemos Batista Inorganic arsenic contamination in rice is a global public concern due to the risks associated. In spite of being an important issue, few...
Thu, 10/27/2016 - 17:45
Publication date: December 2016 Food and Chemical Toxicology, Volume 98, Part A Author(s): Samira A. Brooks, Elizabeth Martin, Lisa Smeester, Matthew R. Grace, Kim Boggess, Rebecca C. Fry Preeclampsia (PE) is a pregnancy disorder characterized by high blood pressure and proteinuria that can cause adverse health effects in both mother and fetus. There is no current cure for PE...
Tue, 10/18/2016 - 12:32
The rise of inorganic–biological hybrid organisms for solar-to-chemical production has spurred mechanistic investigations into the dynamics of the biotic–abiotic interface to drive the development of next-generation systems. The model system, Moorella thermoacetica–cadmium sulfide (CdS), combines an inorganic semiconductor nanoparticle light harvester with an acetogenic bacterium to drive the...
Sun, 10/16/2016 - 22:28
Publication date: Available online 15 October 2016 Food and Chemical Toxicology Author(s): Francesco Cubadda, Marilena D'Amato, Federica Aureli, Andrea Raggi, Alberto Mantovani Dietary exposure of the Italian population to inorganic arsenic has been assessed in the national Total Diet Study (TDS) carried out in 2012-2014. Within the TDS, food samples (&gt;3000) were collected to...
Fri, 10/07/2016 - 11:48
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.6b02639
Tue, 10/04/2016 - 19:49
Publication date: 5 December 2016 , Volume 238 Author(s): Dorota Korsak, Magdalena Szuplewska A total of 127 Listeria isolates from food and food processing environments, including 75 L. innocua, 49 L. welshimeri, 2 L. seeligeri and 1 L. grayi were tested for susceptibility to eight antimicrobials, benzalkonium chloride (BC), cadmium and arsenic. The isolates were also screened for the...
Tue, 08/09/2016 - 12:08
There is growing evidence that Zika virus (ZIKV) can cause devastating infant brain defects and other neurological disorders in humans. However, no specific antiviral therapy is available at present. We tested a series of 2'-C- or 2'-O-methyl–substituted nucleosides, 2'-C-fluoro-2'-C-methyl–substituted nucleosides, 3'-O-methyl–substituted nucleosides, 3'-deoxynucleosides,...
Tue, 08/09/2016 - 02:01
This study developed a new method to extract abalone visceral polysaccharide (AVP) and remove its heavy metals (except for mercury) by combining enzymatic hydrolysis, plate frame filtration, alcohol precipitation, high activated clay absorption with cation exchange resin and anion exchange resin. Alcohol precipitation, dialysis, activated carbon adsorption and high activated clay adsorption were...
Wed, 08/03/2016 - 23:02
Publication date: October 2016 Food and Chemical Toxicology, Volume 96 Author(s): Jinglou Chen, Lifen Du, Jingjing Li, Hongping Song Cadmium (Cd) pollution is a serious environmental problem. Kidney is a main target organ of Cd toxicity. This study was undertaken to investigate the potential protective effects of epigallocatechin-3-gallate (EGCG) against chronic renal injury and...
Mon, 08/01/2016 - 17:00
Toshihiro Watanabe, Eriko Maejima, Tomoko Yoshimura, Masaru Urayama, Aiko Yamauchi, Masako Owadano, Ryosuke Okada, Mitsuru Osaki, Yoshinori Kanayama, Takuro Shinano Soil contains various essential and nonessential elements, all of which can be absorbed plants. Plant ionomics is the study of the accumulation of these elements (the ionome) in plants. The ionomic profile of a plant is affected...
Fri, 07/29/2016 - 22:54
Publication date: October 2016 Food and Chemical Toxicology, Volume 96 Author(s): Marina Ninkov, Aleksandra Popov Aleksandrov, Ivana Mirkov, Jelena Demenesku, Dina Mileusnic, Sofija Jovanovic Stojanov, Natasa Golic, Maja Tolinacki, Lidija Zolotarevski, Dragan Kataranovski, Ilija Brceski, Milena Kataranovski Influence of genetic background on toxicity of oral cadmium (...
Fri, 07/15/2016 - 09:08
Publication date: Available online 13 July 2016 Food and Chemical Toxicology Author(s): Elham Soleimani, Iran Goudarzi, Kataneh Abrari, Taghi Lashkarbolouki Either developmental lead or ethanol exposure can impair learning and memory via induction of oxidative stress, which results in neuronal damage. we examined the effect of combined exposure with lead and ethanol on spatial...
Fri, 07/15/2016 - 00:00
In this study, the effect of enzymes involved in degradation of renal adenosine and l-arginine was investigated in rats exposed to cadmium (Cd) and treated with curcumin, the principal active phytochemical in turmeric rhizome. Animals were divided into six groups (n = 6): control/saline, saline/curcumin 12.5 mg/kg, saline/curcumin 25 mg/kg, Cd/vehicle, Cd/curcumin 12.5 mg/kg, and Cd/curcumin 25 ...
Fri, 07/01/2016 - 00:52
10.1080/19440049.2016.1200750Liubo Pan
Thu, 06/30/2016 - 11:01
The heavy metal cadmium (Cd) is an environmental pollutant that causes adverse health effects in humans and animals. Our previous work demonstrated that oral administration of probiotics can significantly inhibit Cd absorption in the intestines of mice, but further evidence is needed to gain insights into the related protection mode. The goal of this study was to evaluate whether probiotics can...
Thu, 06/23/2016 - 12:13
Background. Tick transmission of Borrelia spirochetes to humans results in significant morbidity from Lyme disease worldwide. Serum concentrations of antibodies against outer surface protein A (OspA) were shown to correlate with protection from infection with Borrelia burgdorferi, the primary cause of Lyme disease in the United States. Methods. Mice transgenic for human immunoglobulin...
Thu, 06/16/2016 - 13:59
Publication date: 1 December 2016 , Volume 212 Author(s): Teresa Chávez-Capilla, Mona Beshai, William Maher, Tamsin Kelly, Simon Foster Humans are exposed to organic arsenic species through their diet and therefore, are susceptible to arsenic toxicity. Investigating the transformations occurring in the gastrointestinal tract will influence which arsenic species to focus on when...
Fri, 06/10/2016 - 09:40
Publication date: Available online 9 June 2016 Author(s): M. Angeles Argudín, Birgit Lauzat, Britta Kraushaar, Patricia Alba, Yvonne Agerso, Lina Cavaco, Patrick Butaye, M. Concepción Porrero, Antonio Battisti, Bernd-Alois Tenhagen, Alexandra Fetsch, Beatriz Guerra Livestock associated methicillin-resistant Staphylococcus aureus (LA-MRSA) has emerged in animal...
Thu, 06/09/2016 - 00:00
The carmine spider mite Tetranychus cinnabarinus (T. cinnabarinus) is a common polyphagous pest that attacks crops, vegetables, flowers, and so on. It is necessary to find lead compounds for developing novel, powerful, and environmentally-friendly acaricides as an alternative approach to controlling the carmine spider mite because of the serious resistance and residual agrochemicals in the...
Thu, 06/02/2016 - 04:06
Publication date: December 2016 , Volume 70 Author(s): Narottam Saha, M.Z.I. Mollah, M.F. Alam, M. Safiur Rahman To investigate the seasonal contamination levels and to evaluate the potential human health risks, ten heavy metals (As, Cd, Co, Cr, Cu, Mn, Ni, Pb, Se, and Zn) were measured in ten different marine fish species from the Bay of Bengal during four seasons. The metal...
Fri, 05/27/2016 - 01:12
Publication date: Available online 26 May 2016 Author(s): Sweta Samantaray, Joao N. Correia, Mariam Garelnabi, Kerstin Voelz, Robin C. May, Rebecca A. Hall The fungal pathogen Cryptococcus neoformans poses a major threat to immunocompromised patients and is a leading killer of human immunodeficiency virus (HIV)-infected patients worldwide. Cryptococci are known to manipulate host...
Tue, 05/10/2016 - 09:33
Publication date: Available online 10 May 2016 Food and Chemical Toxicology Author(s): Roberto Dragone, Laura Ermilov, Gerardo Grasso, Silvia Maggioni, Alberto Mantovani, Chiara Frazzoli Flaxseeds are both a food ingredient and a natural source of antioxidants (e.g. lignans, PUFAs) and pro-oxidant contaminants (e.g. cadmium): the variable mixture of anti- and pro-oxidant...
Mon, 05/09/2016 - 12:45
Abstract In this study detoxification of 3 Chinese Cd-contaminated cultivars (Jinyou463, Yuchi, and Xiangzaoxian 32) of rice was explored. By separation with an alkaline method, Cd concentrations of the starch isolates were decreased from 0.2769, 0.4037, and 0.5156 mg/kg in starting milled rice to 0.1056, 0.1585, and 0.1923 mg/kg, respectively. However, the Cd concentrations reached up to 2.5905...
Fri, 05/06/2016 - 15:40
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.6b01201
Fri, 05/06/2016 - 12:16
Publication date: Available online 5 May 2016 Food and Chemical Toxicology Author(s): Carolyn G. Scrafford, Leila M. Barraj, Joyce S. Tsuji Dietary arsenic exposure and chronic health outcomes are of interest, due in part to increased awareness and data available on inorganic arsenic levels in some foods. Recent concerns regarding levels of inorganic arsenic, the primary form of arsenic...
Wed, 05/04/2016 - 04:32
ScopeReduced expression of tumor suppressor genes (TSG) increases the susceptibility to breast cancer. However, only a small percentage of breast tumors is related to family history and mutational inactivation of TSG. Epigenetics refers to non-mutational events that alter gene expression. Endocrine disruptors found in foods and drinking water may disrupt epigenetically hormonal regulation and...
Thu, 04/28/2016 - 05:35
SUMMARY The natural resistance of Mycobacterium abscessus to most commonly available antibiotics seriously limits chemotherapeutic treatment options, which is particularly challenging for treating cytic fibrosis patients infected with this rapid-growing mycobacterium. New drugs with novel molecular targets are urgently needed against this emerging pathogen. However, the discovery of such new...
Tue, 04/26/2016 - 00:00
Antimicrobial peptides have been accepted as excellent candidates for developing novel antibiotics against drug-resistant bacteria. Recent studies indicate that spider venoms are the source for the identification of novel antimicrobial peptides. In the present study, we isolated and characterized an antibacterial peptide named lycosin-II from the venom of the spider Lycosa singoriensis. It...
Wed, 03/23/2016 - 17:00
Aldo Cavallini, Catia Lippolis, Margherita Vacca, Claudia Nardelli, Alessandra Castegna, Fabio Arnesano, Nicola Carella, Raffaella Depalo Environmental chemicals, such as heavy metals, affect female reproductive function. A biological sensor of the signals of many toxic chemical compounds seems to be the aryl hydrocarbon receptor (AHR). Previous studies demonstrated the environmental of heavy...
Wed, 03/23/2016 - 06:40
Abstract AimsThe aim of this study was to investigate the potential of bioleaching for the treatment of an environmentally hazardous waste, a blast-furnace flue dust designated Theisen sludge. Methods and resultsBioleaching of Theisen sludge was investigated at acidic conditions with A. ferrooxidans in pure and mixed-species culture with Acidiphilium. In shaking-flask experiments bioleaching...
Tue, 03/15/2016 - 12:01
Abstract Microbial biotransformations are major contributors to the arsenic biogeocycle. In parallel with transformations of inorganic arsenic, organoarsenicals pathways have recently been recognized as important components of global cycling of arsenic. The well-characterized pathway of resistance to arsenate is reduction coupled to arsenite efflux. Here we describe a new pathway of arsenate...

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