Heavy Metals

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Sat, 01/30/2021 - 08:05
by Zongying Yu, Jie Song, Li Cheng, Shasha Li, Qun Lu, Yafeng Zhang, Xiaoci Lin, Dadong Liu Background The Peguero-Lo Presti criteria are novel electrocardiographic (ECG) diagnostic criteria for the detection of left ventricular hypertrophy (LVH) and represent the sum of the amplitude of the deepest S wave in any lead with the S wave in lead V4 (SD+SV4). The diagnostic efficacy of the Peguero-Lo...
Sat, 01/30/2021 - 02:02
The Duyen Hai Seaport covering more than 427 hectares of water surface is part of a Duyen Hai thermal power plant complex. In the last years, port operations can lead to impact on air, water, land, and the ecosystem. To evaluate the ecological risk caused by heavy metals at the Duyen Hai Seaport, 17 surficial sediment samples were collected along the ship flow from shoreline to the material...
Fri, 01/29/2021 - 06:11
Author(s): Ivana Mirkov, Aleksandra Popov Aleksandrov, Marina Ninkov, Dina Tucovic, Jelena Kulas, Milica Zeljkovic, Dusanka Popovic, Milena Kataranovski Cadmium (Cd) has been listed as one of the most toxic substances affecting numerous tissues/organs, including the immune system. Due to variations in studies examining Cd effects on the immune system (exposure regime, experimental systems, immune...
Fri, 01/29/2021 - 02:02
The adsorption of Cd by sand-attapulgite cutoff wall backfill media was investigated with batch experiments for different quantities of attapulgite in the mixture (30%, 40%, 60%, and 100%; dry weight). The adsorption capacity of the media for Cd increased with the increase of attapulgite content (Ap). The change of adsorbed amount (qt) with time (t) exhibited two-stage behavior, with more than 80...
Thu, 01/28/2021 - 18:02
Introduction:Environmental arsenic contamination is a major toxicological problem worldwide due to its carcinogenic and nephrotoxic potential.Aim:The purpose of this observational study was to determine the suspected association between urinary arsenic (uAs) and urinary leucine (or leucyl) aminopeptidase 3 (uLAP3) to evaluate uLAP3 as a candidate biomarker of exposure to airborne arsenic....
Thu, 01/28/2021 - 14:05
Zinc, cadmium, and lead in livers, kidneys, and feathers of 48 young and adult Atlantic puffins found dead or dying off the coast of Galicia (Northwest Spain) were determined. The most abundant between the three elements was the essential metal zinc, with highest mean levels (173 ± 9 mg/kg dry weight) in livers. For the two non-essential metals, the highest mean levels of cadmium were found in...
Thu, 01/28/2021 - 00:00
Here, we present the draft genome sequence of Pseudomonas sp. GC01, a cadmium-resistant Antarctic bacterium capable of biosynthesizing CdS fluorescent nanoparticles (quantum dots, QDs) employing a unique mechanism involving the production of methanethiol (MeSH) from methionine (Met). To explore the molecular/metabolic components involved in QDs biosynthesis, we conducted a comparative genomic...
Wed, 01/27/2021 - 08:02
by Aline Clabaut, Céline Grare, Gaëlle Rolland-Valognes, Jean-Guillaume Letarouilly, Chantal Bourrier, Thomas L. Andersen, Tanja Sikjær, Lars Rejnmark, Charlotte Ejersted, Philippe Pastoureau, Pierre Hardouin, Massimo Sabatini, Odile Broux Our preliminary findings have lead us to propose bone marrow adipocyte secretions as new contributors to bone loss. Indeed, using a coculture model based on...
Wed, 01/27/2021 - 06:09
Author(s): Savinda Heshani Arambawatta-Lekamge, Asoka Pathiratne, I. Vayanga Nishani Rathnayake Tropical freshwater ecosystems are increasingly influenced by chemical stressors including heavy metals posing threats to biodiversity. Adequate ecotoxicity data are not available for native tropical freshwater species for deriving water quality guidelines and for conducting ecological risk assessments...
Wed, 01/27/2021 - 06:09
Author(s): Jing Ya, Yifan Xu, Gang Wang, Hongfeng Zhao Cadmium (Cd) is hazardous to human health and it is also highly detrimental to amphibian life. In this study, Bufo gargarizans larvae were exposed to environmentally relevant Cd concentrations of 5, 100 and 200 μg L−1 from Gosner stage (Gs) 26 to Gs 42 of metamorphic climax about 6 weeks. The results showed thyroid structural injuries and...
Wed, 01/27/2021 - 06:09
Author(s): Ning Li, Yali Zhao, Yue Shen, Yongxia Cheng, Mingwu Qiao, Lianjun Song, Xianqing Huang Lead (Pb) is a heavy metal environmental pollutant that can cause functional damage and anemia of immune organs. More and more evidence indicate that the toxicity of lead was related to apoptosis driven by oxidative stress and endoplasmic reticulum stress. This article mainly discusses the protective...
Wed, 01/27/2021 - 06:09
Author(s): Yu Jin, Baofeng Zhang, Junqiao Chen, Weihua Mao, Liping Lou, Chaofeng Shen, Qi Lin The accumulation of cadmium (Cd) in Oryza sativa L., the world’s most significant staple crop, is a health threat to millions of people. The objective of this study was to evaluate the effectiveness of commercially available biofertilizers (with high (BF2) and low organic matter (OM) content (BF1)) on Cd...
Wed, 01/27/2021 - 06:09
Author(s): Ying-Jian Lv, Jia Song, Li-Li Xiong, Rui Huang, Pan Zhu, Ping Wang, Xu-Xia Liang, Jian-Bin Tan, Jing Wang, Shi-Xuan Wu, Qin-Zhi Wei, Xing-Fen Yang Chronic cadmium (Cd) toxicity is a significant health concern, and the mechanism of long-term low-dose Cd exposure on bone has not been fully elucidated yet. This study aimed to assess the association between long-term environmental Cd...
Wed, 01/27/2021 - 06:08
Author(s): Xinru Wang, Wenjing Cui, Miaomiao Wang, Yihuai Liang, Guoying Zhu, Taiyi Jin, Xiao Chen The association between internal cadmium exposure and chronic kidney disease (CKD) has been investigated before. However, few studies have shown the association between dietary cadmium intake and CKD. In this study, we show the association between life-time dietary cadmium intake and CKD based on a...
Wed, 01/27/2021 - 06:08
Author(s): Deliang Yu, Zheng Peng, Huifeng Wu, Xiaoying Zhang, Chenglong Ji, Xiao Peng MicroRNAs (miRNAs) are known to have complicated functions in aquatic species, but little is known about the role of miRNAs in mollusk species under environmental stress. In this study, we performed small RNA sequencing to characterize the differentially expressed miRNAs in different tissues (whole tissues,...
Wed, 01/27/2021 - 04:03
In this research, six neonicotinoid analogs derived from l-proline were synthesized, characterized, and evaluated as insecticides against Xyleborus affinis. Most of the target compounds showed good to excellent insecticidal activity. To the best of our knowledge, this is the first report dealing with the use of enantiopure l-proline to get neonicotinoids. These results highlighted the compound 9...
Wed, 01/27/2021 - 04:03
Cadmium (Cd) is a heavy metal, which is widely used in the industry and daily life. It has a long half-life, so large amounts of Cd can accumulate in humans and become toxic. Chlorogenic acid (CGA) can eliminate free radicals and inhibit lipid peroxidation and is mainly used to prevent metal toxicity. In the present study, mice are given CGA by intraperitoneal injection or gavage, respectively,...
Wed, 01/27/2021 - 02:03
Fasciola hepatica (liver fluke), a significant threat to food security, causes global economic loss for the livestock industry and is re-emerging as a foodborne disease of humans. In the absence of vaccines, treatment control is by anthelmintics; with only triclabendazole (TCBZ) currently effective against all stages of F. hepatica in livestock and humans. There is widespread resistance to TCBZ...
Tue, 01/26/2021 - 14:04
In this work, an effective and simple method is proposed for the simultaneous determination of cadmium, lead and copper in chocolate samples by Square Wave Anodic Stripping Voltammetry (SWASV). An ultrasonic bath was used for the extraction of cadmium, lead and copper from fourteen chocolate samples using HNO3 solution (7 mol L−1). The electrochemical system consisted of a cell with three...
Mon, 01/25/2021 - 22:15
A bacterium designated as strain STP14 was isolated from a sewage treatment plant and identified as Acinetobacter calcoaceticus based on 16S ribosomal RNA gene sequencing. Strain STP14 exhibited resistance to several metals such as mercury, cobalt, copper, nickel, lead, and cadmium. Among these metals, the bacterium showed maximum resistance to cadmium in concentration up to 1200 mg/L. The...
Mon, 01/25/2021 - 16:00
Arsenic (As) accumulation in rice grain is a significant public health concern. Inorganic As (iAs) is of particular concern because it has increased toxicity as compared to organic As. Irrigation management practices, such as alternate wetting and drying (AWD), as well as genotypic differences between cultivars, have been shown to influence As accumulation in rice grain. A 2 year field study...
Mon, 01/25/2021 - 06:09
Author(s): Jun-Song Li, Nobuo Suzui, Yuji Nakai, Yon-Gen Yin, Satomi Ishii, Shu Fujimaki, Naoki Kawachi, Hiroki Rai, Takashi Matsumoto, Kanna Sato-Izawa, Naoko Ohkama-Ohtsu, Shin-ichi Nakamura Glutathione (GSH) is a tripeptide involved in controlling heavy metal movement in plants. Our previous study showed that GSH, when site-specifically applied to plant roots, inhibits Cd translocation from...
Sun, 01/24/2021 - 06:10
Author(s): Lu Yiming, Han Yanfei, Yin Hang, Cong Yimei, Shi Guangliang, Li Shu This study was aimed to explore the possible mechanism of environmental metal cadmium (Cd) inducing apoptosis of pig lymph nodes.
Sun, 01/24/2021 - 06:08
Author(s): Chunlin Yu, Mohan Qiu, Zengrong Zhang, Xiaoyan Song, Huarui Du, Han Peng, Qingyun Li, Li Yang, Xia Xiong, Bo Xia, Chenming Hu, Jialei Chen, Xiaosong Jiang, Chaowu Yang As a ubiquitous heavy metal, cadmium (Cd) is highly toxic to various organs. However, the effects and molecular mechanism of Cd toxicity in the chicken heart remain largely unknown. The goal of our study was to...
Sun, 01/24/2021 - 02:03
The rapid industrial development has led to serious cadmium (Cd) pollution. Cd is a toxic heavy metal placing severe health threat to human. Cd can enter the body through the atmosphere, water, soil and food, and has a long half-life (10–30 years), it largely accumulates in kidneys, liver, bone and other organs and causes irreversible damage to the target organs. Cd pollution has also further...
Fri, 01/22/2021 - 22:15
Background: Salinity is one of the main threats that can cause crop yield losses by limiting plant growth. Several important cultivated crops including wheat exhibit sensitivity to salt stress by severe yield reductions. Approaches to improve salt resistance are critical for improved food production in the future. Aims: Silicon (Si) is well known for its role as quasi‐essential element to enhance...
Fri, 01/22/2021 - 04:02
The successful treatment of Helicobacter pylori infections is becoming increasingly difficult due to the rise of resistance against current broad spectrum triple therapy regimens. In the search for narrow-spectrum agents against H. pylori, a high-throughput screen identified two structurally related thienopyrimidine compounds that selectively inhibited H. pylori over commensal members of the gut...
Fri, 01/22/2021 - 02:02
Anthropogenic cadmium (Cd) in alpine soils is mainly from long-range atmospheric transport. Because of the high toxicity and mobility, whether the accumulation of Cd in the soils threats to ecosystem safety remains unclear. The fractions of soil Cd along three altitudinal transects on Gongga Mountain were analyzed to decipher the drivers on its mobility, and its contamination and health risk were...
Thu, 01/21/2021 - 22:09
Mitochondria are important organelles in human cells, providing more than 95% of the energy. However, some drugs and environmental chemicals could induce mitochondrial dysfunction, which might cause complex diseases and even worsen the condition of patients with mitochondrial damage. Some drugs have been withdrawn from the market due to their severe mitochondrial toxicity, such as troglitazone....
Thu, 01/21/2021 - 10:03
New treatment strategies are required for cryptococcosis, a leading mycosis in HIV-AIDS patients. Following the identification of Cryptococcus proteins differentially expressed in response to fluconazole, we targeted farnesyl pryrophosphate synthetase (FPPS), an enzyme in the squalene biosynthesis pathway, using nitrogenous bisphosphonates. We hypothesized that these would disrupt squalene...
Thu, 01/21/2021 - 10:03
Resistance mechanisms of Pseudomonas aeruginosa to ceftolozane/tazobactam (C/T) were assessed on a collection of 420 nonredundant strains nonsusceptible to ceftazidime (MIC > 8 μg/ml) and/or imipenem (>4 μg/ml), collected by 36 French hospital laboratories over a one-month period (the GERPA study). Rates of C/T resistance (MIC > 4/4 μg/ml) were equal to 10% in this population (...
Thu, 01/21/2021 - 06:13
Author(s): Débora Rebechi, Angela Maria Palacio-Cortés, Vinicius Sobrinho Richardi, Tiago Beltrão, Maiara Vicentini, Marco Tadeu Grassi, Simone Braga da Silva, Thiago Alessandre, Simone Hasenbein, Richard Connon, Mário Antônio Navarro-Silva In-vitro effects of sub-lethal concentrations of malathion, phenanthrene (Phe) and cadmium (Cd) were tested on Chironomus sancticaroli larvae in acute...
Wed, 01/20/2021 - 04:02
Mining is one of the major sources of heavy metals in most developing countries and this has become a major health concern to the populace due to the possibility of food contamination with these heavy metals. We investigated the levels of titanium (Ti), manganese (Mn), nickel (Ni), copper (Cu), zinc (Zn), lead (Pb), rubidium (Rb), strontium (Sr), selenium (Se), niobium (Nb) and vanadium (V) in 64...
Tue, 01/19/2021 - 14:02
A risk assessment was performed to estimate the lead (Pb) dietary intake in the Brazilian population. Data on Pb concentration in food were obtained through a systematic review with meta-analyses and from the GEMS/Food database, both involving data through 2018. Food consumption data were obtained from a Brazilian official dietary survey. Pb dietary intakes were estimated by a deterministic...
Tue, 01/19/2021 - 06:17
Author(s): Chohelee Choudhury, Ritwik Mazumder, Rajib Biswas, Mahuya Sengupta A vast range of research related to the toxicity of the heavy metal cadmium (Cd) has been carried out in a wide variety of fish species. However, Cd induced immunomodulation in monocytes/macrophages of Channa punctatus Bloch. has rarely been explored. The present study was designed to determine Cd induced immune...
Tue, 01/19/2021 - 06:17
Author(s): Ulysses M. Montojo, Bernajocele Jalyn S. Baldoza, Flordeliza D. Cambia, Kathlene Cleah D. Benitez, Karl Bryan S. Perelonia, Ana Trinidad F. Rivera The coastal provinces of Manila Bay contribute 38% of mussel and oyster's production in the Philippines. However, concerns in the consumers' health are rising due to the possible pollution in the bay waters that may contaminate the bivalves...
Tue, 01/19/2021 - 06:13
Author(s): Le-Xing You, Rui-Rui Zhang, Jia-Xin Dai, Zi-Ting Lin, Yuan-Ping Li, Martin Herzberg, Jin-Lin Zhang, Hend Al-Wathnani, Cheng-Kang Zhang, Ren-Wei Feng, Hong Liu, Christoper Rensing Bioremediation of Cd contaminated environments can be assisted by plant-growth-promoting bacteria (PGPB) enabling plant growth in these sites. Here a gram-negative Burkholderia contaminans ZCC was isolated...
Tue, 01/19/2021 - 06:13
Author(s): Muhammad Imran, Saddam Hussain, Muhammad Shoaib Rana, Muhammad Hamzah Saleem, Fahd Rasul, Kanwar Haris Ali, Mouloumdema Pouwedeou Potcho, Shenggang Pan, Meiyang Duan, Xiangru Tang Cadmium (Cd) toxicity causes severe perturbations in nitrogen (N) uptake and assimilation, and thereby interrupts normal plant growth. Molybdenum (Mo), a necessary trace element, plays important roles in N...
Tue, 01/19/2021 - 06:13
Author(s): Ying Wang, Xitong Wang, Weiqi Lan, Yuming Wei, Fei Xu, Heng Xu Large amounts of cadmium (Cd) have been discharged into soil with the rapid development of industry. In this study, we revealed the impacts of Coprinus comatus (C. comatus) and Pleurotus cornucopiae (P. cornucopiae) on soil and the tolerance responses of macrofungi in the presence of Cd by the analysis of soil biochemical...
Tue, 01/19/2021 - 06:13
Author(s): Queilenin Ramos, M. Aurora Armienta, Alejandra Aguayo, Olivia Cruz Geothermal energy is a low-pollution energy source. However, air, soil, and water near geothermal plants may be affected by their operation. One of the largest geothermal energy sources in the world, Cerro Prieto, has a capacity of 720 MW and is located in northwest Mexico near an agricultural area. The abstracted...
Tue, 01/19/2021 - 04:02
As one of the most toxic forms of arsenic, inorganic As(III) is easy to accumulate in rice, leading to severe public health problems. Effective control of As(III) requires the development of fast analytical methods for its detection with high sensitivity and specificity. Toward this end, in this work, we report the fabrication of an As(III) electrochemical sensor based on a solution-gated...
Tue, 01/19/2021 - 02:03
Abstract The low rate of discovery and rapid spread of resistant pathogens have made antibiotic discovery a worldwide priority. In cell-based screening, the mechanism of action (MOA) is identified after antimicrobial activity. This increases rediscovery, impairs low potency candidate detection, and does not guide lead optimization. In this study, high-throughput Fourier-transform infrared (FTIR...
Tue, 01/19/2021 - 02:02
This study reports the polyphenol profile of helencha (Enydra fluctuans Lour.), an underutilised, aquatic leafy vegetable, based on high resolution accurate mass analysis. The methanolic extract of helencha leaves was screened by ultra-high performance liquid chromatography with quadrupole time of flight mass spectrometry (LC-QToF-MS). An in-house developed database of phytochemical metabolites...
Thu, 01/14/2021 - 16:00
Environmental adaptation of Listeria monocytogenes is a complex process involving various mechanisms that can contribute to their survival in the environment, further spreading throughout the food chain and the development of listeriosis. The aim of this study was to analyze whole-genome sequencing data in a set of 270 strains of L. monocytogenes derived from human listeriosis cases and food and...
Thu, 01/14/2021 - 06:14
Author(s): Fasih Ullah Haider, Cai Liqun, Jeffrey A. Coulter, Sardar Alam Cheema, Jun Wu, Renzhi Zhang, Ma Wenjun, Muhammad Farooq Cadmium (Cd) is an unessential trace element in plants that is ubiquitous in the environment. Anthropogenic activities such as disposal of urban refuse, smelting, mining, metal manufacturing, and application of synthetic phosphate fertilizers enhance the concentration...
Thu, 01/14/2021 - 04:02
Pyrazolo[1,5-a]pyrimidin-7(4H)-one was identified through high-throughput whole-cell screening as a potential antituberculosis lead. The core of this scaffold has been identified several times previously and has been associated with various modes of action against Mycobacterium tuberculosis (Mtb). We explored this scaffold through the synthesis of a focused library of analogues and identified key...
Thu, 01/14/2021 - 02:02
Smelting activities are an important source of heavy metals in soil. More seriously, oral ingestion of crops growing in contaminated soil potentially cause harmful effects on human health. The main purpose of this study is to apply the in vitro model (PBET) and Monte Carlo Simulation (MSC) to the health risk assessment process in order to more accurately and realistically evaluate health risks of...
Wed, 01/13/2021 - 16:00
Different anthropogenic activities result in the continuous increase of metal lead (Pb) in the environment and adversely affect living organisms. Therefore, it is important to investigate the tolerance mechanism in a model organism. Chlamydomonas reinhardtii is an important green eukaryotic model microalga for studying different kinds of biological questions. In this study, the responses of C....
Wed, 01/13/2021 - 10:03
ABSTRACT An outer membrane protein A (OmpA) from Acinetobacter sp. strain SA01 was identified and characterized in-depth based on the structural and functional characteristics already known of its homologues. In silico structural studies showed that this protein can be a slow porin, binds to peptidoglycan, and exhibits emulsifying properties. Characterization of the recombinant SA01-OmpA, based...
Wed, 01/13/2021 - 06:07
Author(s): Yao Lu, Junru Wu, Wenduo Gu, Zhijun Huang, Zhihao Shu, Miao Huang, Jingyuan Chen, Mengli Zhou, Yuanyuan Bai, Xiang Chen, Yi Xiao, Minxue Shen, Dan Luo, Qihong Deng, Liyuan Chai, Meian He, Jicheng Gong, Hong Yuan, Qingbo Xu, Jingjing Cai Cadmium is the most prevalent form of heavy metal contaminant globally and its exposure rises serious health concern. Chronic exposure to cadmium...

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