Heavy Metals

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Sat, 12/19/2020 - 22:09
Lung cancer is the most common neoplasm and the primary cause‐related mortality in developed and in most of nondeveloped countries. Epidemiological studies have demonstrated that even at low arsenic doses, the lungs are one of the main target organs and that chronic arsenic exposure has been associated with an increase in lung cancer development. Among the risk factors for cancer, arsenic...
Fri, 12/18/2020 - 22:10
To improve our understanding of underlying toxic mechanisms, it is important to evaluate differences in effects that a variety of metals exert at concentrations representing the same toxic level to the organism. Therefore, the main goal of the present study was to compare the effects of waterborne copper (Cu(II)), zinc (Zn(II)) and cadmium (Cd (II)) on a freshwater fish, the common carp (Cyprinus...
Fri, 12/18/2020 - 16:00
The presence of cadmium in rice stems is a limiting factor that restricts its function as biomass. In order to prevent potential risks of heavy metals in rice straws, this study introduced a fast detection method of cadmium in rice stems based on laser induced breakdown spectroscopy (LIBS) and chemometrics. The wavelet transform (WT), area normalization and median absolute deviation (MAD) were...
Thu, 12/17/2020 - 16:00
Water utilities treat drinking water by adding phosphate to prevent metal dissolution from water pipe work systems and particularly lead poisoning. Phosphate can be a limiting nutrient for microbial biofilms in DWDS, yet its effects on these microbial consortia are not well understood. This research presents results from phosphate dosing experiments using a real scale chlorinated DWDS, comparing...
Thu, 12/17/2020 - 08:04
Formamidinium lead iodide (CH(NH2)2PbI3, FAPI) thin films have been deposited on glass substrates at 150 °C using ambient pressure aerosol assisted chemical vapour deposition (AACVD). The films have been analysed by a range of techniques including powder X-ray diffraction (pXRD), scanning electron microscopy (SEM), energy dispersive X-ray (EDX) spectroscopy, and UV–Vis–NIR absorption spectroscopy...
Thu, 12/17/2020 - 06:19
Author(s): Babar Hussain, Muhammad Jawad Umer, Jumei Li, Yibing Ma, Yawar Abbas, Muhammad Nadeem Ashraf, Nazia Tahir, Aman Ullah, Nirmali Gogoi, Muhammad Farooq A high concentration of toxic heavy metal cadmium (Cd) in the paddy soils and its translocation and subsequent accumulation in the rice grain and the food chain is a global environmental issue. Mechanistic understanding of soil properties...
Thu, 12/17/2020 - 06:13
Author(s): Chao Zhao, Chao Peng, Pengfei Wang, Sigang Fan, Lulu Yan, Lihua Qiu Cell division cycle 37 (Cdc37) is an important cytoplasmic phosphoprotein, which usually functions as a complex with heat shock protein 90 (Hsp90), to effectively reduce the damage caused by heavy metals, such as cadmium (Cd), in aquatic animals. The high toxicity of Cd in aquatic systems generally has a deleterious...
Thu, 12/17/2020 - 06:13
Author(s): Xingyuan Li, Ting Geng, Wenjie Shen, Jingru Zhang, Yongzhang Zhou Cadmium (Cd) is a highly toxic heavy metal that occurs widely in the environment and poses extensive threats to human health, animals, and plants. This study aims to identify and apportion multi-source and multi-phase Cd pollution from natural and anthropogenic inputs using ensemble models that include random forest (RF...
Sun, 12/13/2020 - 02:01
On a daily basis, aquatic ecosystem is exposed to heavy metals, drugs, and chemicals; the continuous exposure results in a toxic effect, depending on the dose and duration of exposure. Studies have confirmed tardigrade to be highly tolerant to very high temperature, pressure, gravity, etc. This study aimed at confirming various toxic damages caused by exposure to cadmium solution and the...
Sat, 12/12/2020 - 22:09
Yanghe decoction is a traditional Chinese medicine prescription and has been used for breast cancer treatment for many years. However, the effective ingredients in the decoction have not been identified. The expression of poly (ADP‐ribose) polymerase‐1 is highly related to breast cancer. Using poly (ADP‐ribose) polymerase‐1 as a probe, we expressed the haloalkane dehalogenase‐tagged protein in E...
Sat, 12/12/2020 - 08:01
by Cong Li, Yu Liu, Jing Tian, Yanshu Zhu, Jinjuan Fan Sucrose metabolism contributes to the growth and development of plants and helps plants cope with abiotic stresses, including stress from Cd. Many of these processes are not well-defined, including the mechanism underlying the response of sucrose metabolism to Cd stress. In this study, we investigated how sucrose metabolism in maize varieties...
Sat, 12/12/2020 - 08:01
The present study was undertaken to investigate the physicochemical and microbiological qualities of melon seed powder sold in some open Ghanaian markets. Twenty-five samples of powder were collected randomly from each of four major markets and analyzed for moisture, pH, total ash, acid insoluble ash, and free fatty acids (FFA) using standard methods. The microbial population was determined using...
Fri, 12/11/2020 - 22:08
Moringa oleifera Lam. extract (MOE) led to the activation of the detoxifying enzyme systems in the Pb (II)‐intoxicated rodents. Administration of MOE offers protection against PbAc‐intoxicated rodents’ brain tissues by inhibiting oxidative stress, apoptosis and inflammation, via attenuating NF‐κB signaling pathways. Abstract In this study, we investigate the potential protective effect of Moringa...
Fri, 12/11/2020 - 22:07
In addition to known allergens, other proteins in pollen can aid the development of an immune response in allergic individuals. The contribution of the “unknown” protein allergens is apparent in phylogenetically related species where, despite of high homology of the lead allergens, the degree of allergenic potential can vary greatly. The aim of this study was to identify other potentially...
Fri, 12/11/2020 - 06:05
Author(s): Hongyan Guo, Jian Ji, Kaimin Wei, Jiadi Sun, Yinzhi Zhang, Xiulan Sun Deoxynivalenol (DON) and cadmium (Cd) not only share target organs, but also share certain upstream and downstream toxic pathways. DON and Cd may accumulate in the food chain, increasing the risk of joint exposure. Therefore, there is a significant need to characterize the joint toxicity of these two compounds. The...
Thu, 12/10/2020 - 06:08
Author(s): Sara W. Erasmus, Lisanne van Hasselt, Linda M. Ebbinge, Saskia M. van Ruth For centuries, the colour of foods has played a significant role in the way products are perceived and valued. Generally, the more vibrant the product, the higher its quality and price. For modern-day consumers, various brightly coloured foods are known as superfoods and often consumed at higher concentrations...
Thu, 12/10/2020 - 04:03
Consumption of seafood is a common route of cadmium ion (Cd2+) exposure to consumers. The seafood matrices may alter the toxicity profile of Cd2+ due to the interaction between Cd2+ and biomacromolecules in seafood. In this study, enhanced cytotoxicity of Cd2+ was found in the presence of an abalone gonad sulfated polysaccharide (AGSP) and the mechanism was investigated at a metabolic level. The...
Wed, 12/09/2020 - 06:13
Author(s): Shulian Wang, Bin Ji, Baihui Cui, Yingqun Ma, Dabin Guo, Yu Liu So far, the microalgal-bacterial granular sludge process has attracted growing interest as an emerging wastewater treatment technology. Cadmium ion (Cd2+) commonly found in wastewater is toxic to microorganisms, thus its effect on microalgal-bacterial granules was investigated in this study. Results showed that Cd2+ at the...
Wed, 12/09/2020 - 06:10
Author(s): Yuan Zhao, Zi-Fa Li, Dong Zhang, Zhen-Yong Wang, Lin Wang Autophagy dysregulation plays a pivotal role in cadmium (Cd)-induced nephrotoxicity. Quercetin (Qu), a flavonoid antioxidant with autophagy-enhancing effect, has protective effect on Cd-induced toxicity, but whether it can prevent Cd-induced nephrotoxicity via restoration of autophagy remains unknown. Here, primary rat proximal...
Tue, 12/08/2020 - 22:12
Aim Fluorescent semiconductor nanoparticles or Quantum Dots (QDs) have excellent properties as photosensitizers in photodynamic therapy. This is mainly consequence of their nanometric size and the generation of light‐activated redox species. In previous works we have reported the low‐cost biomimetic synthesis of glutathione (GSH) capped QDs (CdTe‐GSH QDs) with high biocompatibility. However, no...
Tue, 12/08/2020 - 22:11
Itai‐itai (Japanese, “It hurts! It hurts!”) disease (IID), a form of osteomalacia, can be induced in ovariectomized rats by long‐term administration of cadmium (Cd). This IID rat model shows severe anemia, severe nephropathy, and osteomalacia accompanied by iron (Fe) deposition at the mineralization front. We characterized the pathogenesis of Cd‐induced bone lesions by investigating the...
Tue, 12/08/2020 - 08:03
by Vicky L. M. N. Soomers, Winette T. A. van der Graaf, Shane Zaidi, Suzanne E. J. Kaal, Andrew J. Hayes, Bart H. W. B. Schreuder, Robin L. Jones, Ingrid M. E. Desar, Olga Husson Introduction Sarcomas are rare tumours. Early diagnosis is challenging, but important for local control and potentially survival and quality of life(QoL). We investigated (1)the route to diagnosis (RtD) experienced by...
Sun, 12/06/2020 - 06:12
Author(s): Qiang Lu, Xin-yue Zhou, Yang-wen Wu, Teng-ge Mi, Ji Liu, Bin Hu Heavy metal pollutants generated from municipal solid waste (MSW) incineration are mainly concentrated in the fly ash, among which lead species have received considerable attention due to their high content and biotoxicity. CaO is an active component in fly ash to adsorb heavy metal species. In this study, based on density...
Fri, 12/04/2020 - 04:03
To control the development of resistance to conventional insecticides acting as γ-aminobutyric acid (GABA) receptor antagonists (e.g., fipronil), new GABAergic 5,5-disubstituted 4,5-dihydropyrazolo[1,5-a]quinazolines were designed via a scaffold-hopping strategy and synthesized with a facile method. Among the 50 target compounds obtained, compounds 5a, 5b, 7a, and 7g showed excellent insecticidal...
Thu, 12/03/2020 - 18:03
It is well established that hexachlorophene, which is used as an antibacterial agent, causes intramyelinic edema in humans and animal models. The hexachlorophene myelinopathy model, in which male Sprague-Dawley rats received 25 to 30 mg/kg hexachlorophene by gavage for up to 5 days, provided an opportunity to compare traditional neuropathology evaluations with magnetic resonance microscopy (MRM)...
Thu, 12/03/2020 - 16:00
Lysine (Lys) is indispensable nutritionally, and its levels in plants are modulated by both transcriptional and post-transcriptional control during plant ontogeny. Animal glutamate receptor homologs have been detected in plants, which may participate in several plant processes through the Lys catabolic products. Interestingly, a connection between Lys and serotonin metabolism has been established...
Thu, 12/03/2020 - 16:00
Calcium (Ca2+) ion is a critical ubiquitous intracellular second messenger, acting as a lead currency for several distinct signal transduction pathways. Transient perturbations in free cytosolic Ca2+ ([Ca2+]cyt) concentrations are indispensable for the translation of signals into adaptive biological responses. The transient increase in [Ca2+]cyt levels is sensed by an array of Ca2+ sensor relay...
Thu, 12/03/2020 - 02:02
Vegetation along roadsides reduces soil erosion, increases filtering of water runoff, and acts as a biodiversity corridor. The purpose of this study was to assess soil properties and evaluate their effect on vegetation establishment in roadsides. Furthermore, the effects of shoulder type (paved and unpaved) and time since seeding (0–1 year, 2–4 years, and ≥ 5 years) on soil properties were also...
Wed, 12/02/2020 - 08:03
Plant pathogenic fungi often developed specialized infection structures to breach the outer surface of a host plant. These structures, called appressoria, lead the invasion of the plant by the fungal hyphae. Studies in different phytopathogenic fungi showed that appressorium formation seems to be subordinated to the cell cycle. This subordination...
Wed, 12/02/2020 - 06:13
Author(s): Heba Mohamed Mohamed El-Sherbiny, Khalid Ibrahim Sallam Two hundred fish samples comprising 100 each of European sardine (Sardina pilchardus) and Atlantic mackerel (Scomber Scombrus) collected from the Mediterranean Sea Coast, Egypt, were evaluated for their residual contents of mercury (Hg), lead (Pb) and cadmium (Cd) along with the potential risks posed by residual metal content on...
Wed, 12/02/2020 - 06:12
Author(s): Ziyang Luo, Hanying Duan, Yuncheng Yang, Wentao Zhang, Hosahalli S. Ramaswamy, Chao Wang Cadmium (Cd) is a nonessential heavy metal and ranks seventh on the list of World Health Organization Agency's Toxic Substances. In this study, ultrasound assisted extraction (UAE) was used for Cd decontamination of rice grains and rice flour. Extraction conditions were developed [particle size,...
Tue, 12/01/2020 - 08:03
by Sutanu Nandi, Piyali Ganguli, Ram Rup Sarkar Essential gene prediction helps to find minimal genes indispensable for the survival of any organism. Machine learning (ML) algorithms have been useful for the prediction of gene essentiality. However, currently available ML pipelines perform poorly for organisms with limited experimental data. The objective is the development of a new ML pipeline...
Tue, 12/01/2020 - 08:03
by Biplob Kumar Modak, Partha Gorai, Devendra Kumar Pandey, Abhijit Dey, Tabarak Malik Introduction To explore the ethnobiological wisdom of the tribals of three western districts of West Bengal, India against poisonous and non-poisonous bites and stings, a quantitative approach was adopted. These age-old yet unexplored knowledge can be utilized in finding lead-molecules against poisonous and non...
Mon, 11/30/2020 - 16:00
The role of ascorbate (AsA) in antioxidant defense system-associated resistance to cadmium (Cd) in oilseed rape plants has not yet been clearly demonstrated. The present study investigated the critical role of exogenous AsA on the physiological and biochemical responses of reactive oxygen species (ROS) and antioxidant scavenging defense systems in oilseed rape (Brassica napus L. cv. Tammi)...
Mon, 11/30/2020 - 06:15
Author(s): Ning Li, Di Zhang, Shuai Cao, Mingwu Qiao, Pingan Zhang, Qiuyan Zhao, Yue Shen, Xianqing Huang, Lianjun Song The heavy metal lead in the environment is a neurotoxin with very strong biological toxicity which can cause serious damage to the learning and memory ability of humans and animals, folic acid can be involved in biological process to prevent impaired learning and memory. however...
Sun, 11/29/2020 - 06:11
Author(s): Haq Nawaz, Muhammad Anwar-ul-Haq, Javaid Akhtar, Muhammad Arfan The wastewater utilization for irrigation purposes is common practice in peri-urban areas located in vicinity of developed cities. This water contains elements like chromium (Cr), nickel (Ni), cadmium (Cd) and nitrate (NO3-N) that poses health risk when exposed to human. In this study effect of wastewater irrigation from...
Sun, 11/29/2020 - 06:11
Author(s): Ling Ou, Haixia Wang, Zhidi Wu, Panpan Wang, Li Yang, Xiaoyun Li, Kehuan Sun, Xiaofeng Zhu, Ronghua Zhang Cadmium is an environmental metal pollutant that has been a focus of research in recent years, which is reported to cause bone disease; however, its skeletal toxicity and the mechanism involved are not yet fully known. Therefore, this study used MC3T3-E1 subclone 14 cells to...
Sat, 11/28/2020 - 14:09
High levels of lead (Pb) in the soil is a serious issue in the city of Kabwe, Zambia. Phytoremediation is an effective approach to revive the life-supporting functions of the soils. Locally available soil amendments, such as chicken manure, can strengthen phytoremediation. This study aims to find an appropriate combination of a locally available Pb hyperaccumulator, lemongrass (Cymbopogon...
Sat, 11/28/2020 - 02:02
The rapid growth of human population and global industrialization has resulted in the generation of larger amounts of wastewater containing various pollutants, among which toxic heavy metals. Adsorption is efficient for this purpose, but its application is limited by the high cost of adsorbent materials. Chitosan (CS) and phosphorylated microcellulose (PMC) have a high potential as low-cost and...
Fri, 11/27/2020 - 12:01
The opioid epidemic in the United States, along with a lack of adequate harm reduction services, has contributed to a sharp rise in hepatitis C virus (HCV) infections. Despite considerable evidence of the effectiveness of HCV treatment in people who inject drugs (PWID), and recommendations from clinical guidelines to prioritize treatment in PWID, there are multiple barriers to broad uptake of HCV...
Thu, 11/26/2020 - 18:02
Lead is a ubiquitous heavy metal toxin of significant public health concern. Every individual varies in their response to lead’s toxic effects due to underlying genetic variations in lead metabolizing enzymes or proteins distributed in the population. Earlier studies, including our lab, have attributed the influence of ALAD (δ-Aminolevulinate dehydratase) polymorphism on blood lead retention and...
Thu, 11/26/2020 - 00:00
As the field of forensic DNA analysis has started to transition from genetics to genomics, new methods to aid in crime scene investigations have arisen. The development of informative single nucleotide polymorphism (SNP) markers has led the forensic community to question if DNA can be a reliable &ldquo;eye-witness&rdquo; and whether the data it provides can shed light on unknown...
Wed, 11/25/2020 - 08:02
by José M. Di Diego, Bence Patocskai, Hector Barajas-Martinez, Virág Borbáth, Michael J. Ackerman, Alexander Burashnikov, Jérôme Clatot, Gui-Rong Li, Victoria M. Robinson, Dan Hu, Charles Antzelevitch Background J wave syndromes (JWS), including Brugada (BrS) and early repolarization syndromes (ERS), are associated with increased risk for life-threatening ventricular arrhythmias. Pharmacologic...
Wed, 11/25/2020 - 06:12
Author(s): Muhammad Adrees, Zahra Saeed Khan, Muhammad Hafeez, Muhammad Rizwan, Khalid Hussain, Muhammad Asrar, Mohammed Nasser Alyemeni, Leonard Wijaya, Shafaqat Ali A pot study was conducted to explore the effectiveness of zinc oxide nanoparticles (ZnO NPs) foliar exposure on growth and development of wheat, zinc (Zn) and cadmium (Cd) uptake in Cd-contaminated soil under various moisture...
Tue, 11/24/2020 - 12:02
ABSTRACT Mercury superfamily proteins, i.e. inner membrane-spanning proteins (MerC, MerE, MerF and MerT) and a periplasmic mercury-binding protein (MerP), transport mercury into the cytoplasm. A previous study demonstrated that a Mer transporter homolog exhibits cadmium transport activity; based on this, the present study aimed to evaluate the cadmium transport activity of MerC, MerE, MerF and...
Mon, 11/23/2020 - 08:02
Deficiency of selenium (Se) will lead to malnutrition and decreased immune function of the body. There is a common phenomenon of Se deficiency in foods. In this study, different concentrations of sodium selenite (Na2SeO3) were applied to Moringa oleifera grownin soil. The purpose was to explore the feasibility of Se biofortification of M. oleifera root. The effect of exogenous Se on the...
Mon, 11/23/2020 - 06:11
Author(s): Shan Wang, Qi Li, Suzhen Huang, Wei Zhao, Zheng Zheng Recently, the pollution of microplastics (MPs) in the global freshwater environment has become increasingly problematic, but there are few studies on the freshwater environment risks of MPs. The present study, therefore, has investigated the single and combined effects of MPs and lead (Pb) on the freshwater algal Microcystis...
Mon, 11/23/2020 - 02:03
Cadmium (Cd) is a harmful element to human health and biodiversity. The removal of Cd from groundwater is of great significance to maintain the environmental sustainability and biodiversity. In this work, a novel low-temperature roasting associated with alkali was applied to synthesize an eco-friendly adsorbent using coal fly ash. Scanning electron microscopy, Fourier transform infrared...
Sat, 11/21/2020 - 22:11
BACKGROUND Porphyra haitanensis now faces serious heavy metal pollution problems. Natural deep eutectic solvents (NADESs) have been recognized as a novel class of sustainable solvents, which can be used for heavy metal removal. In this study, 28 kinds of NADESs were prepared and investigated as eluent in the removal of lead (Pb), cadmium (Cd), chromium (Cr), arsenic (As), and copper (Cu) from P....
Fri, 11/20/2020 - 04:02
β-Ketoacyl-acyl carrier protein synthase III (KAS III, FabH) is essential for bacterial fatty acid biosynthesis. Recent studies indicate that FabH can be a potential target for bactericide development. In the present study, an immobilized FabH column was developed and used to screen FabH inhibitors from complex natural product extracts. Combined with HPLC, four secondary metabolites, alternariol...

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