Heavy Metals

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Fri, 11/20/2020 - 02:04
Cadmium (Cd) is highly toxic metal for plant metabolic processes even in low concentration due to its longer half-life and non-biodegradable nature. The current study was designed to assess the bioremediation potential of a Cd-tolerant phytobeneficial bacterial strain Bacillus sp. SDA-4, isolated, characterized and identified from Chakera wastewater reservoir, Faisalabad, Pakistan, together with...
Fri, 11/20/2020 - 00:00
Antibiotic resistance is one of the major current global health crises. Because of increasing contamination with antimicrobials, pesticides, and heavy metals, the aquatic environment has become a hotspot for emergence, maintenance, and dissemination of antibiotic and heavy metal resistance genes among bacteria. The aim of the present study was to determine the co-resistance to quinolones,...
Wed, 11/18/2020 - 22:11
Cadmium (Cd) is an occupational and environmental heavy metal pollutant derived from many sources that is linked to endothelial homeostasis. The endothelium is an important site of Cd deposition, while increasing evidence has revealed there is a close relationship between endothelial dysfunction and abnormal lipid metabolism. However, the effects of the alterations in lipid metabolism on...
Wed, 11/18/2020 - 08:02
Political polarization has intensified in the lead-up to the 2020 US presidential election, with liberal and conservative politicians hurling insults at one another, journalists highlighting ways in which Americans are deeply divided, and parts of the general American public condoning violence if their side does not win the upcoming election....
Wed, 11/18/2020 - 02:03
The main purpose of the present study was to investigate the potential use of metabolic parameters as non-specific biomarkers of pollution. The Igarapé do Quarenta is a small urban river crossing an industrial area in the city of Manaus, Amazon, and receives the city wastewater without treatment. The fish tambaqui (Colossoma macropomum) were exposed to water collected from two different sites of...
Wed, 11/18/2020 - 02:02
Tortoise shell is not only an armor, but also an important structure for storing nutrients for tortoise. The shell from one tortoise strain, Chinemys reevesii (CR), has long been used as a traditional Chinese medicine (TCM). Nowadays, massive CR shells are also processed into healthy food in Asian countries. Despite large-scale culture of CR in nowadays, there still exist massive counterfeit CR...
Wed, 11/18/2020 - 00:00
Tuberculosis, caused by Mycobacterium tuberculosis (M. tuberculosis), is one of the leading causes of human deaths globally according to the WHO TB 2019 report. The continuous rise in multi- and extensive-drug resistance in M. tuberculosis broadens the challenges to control tuberculosis. The availability of a large number of completely sequenced genomes of M. tuberculosis has provided an...
Tue, 11/17/2020 - 22:14
The Contamination agricultural soils and food by cadmium(cd) is one of the major concerns of the world. The field experiments were conducted to investigate the effects of silicon (Si) fertilizer on bioavailability and accumulation of Cd in soil, Cd chemical fractions, dynamic changes of soil pH, available Cd content and Cd content of various parts of rice plants. The results revealed that...
Tue, 11/17/2020 - 18:03
Platinum group metals (PGMs) are widely applied in the field of catalysts due to their excellent catalyst activity and high-temperature stability. The rapid generation of the waste catalyst has become the significant characteristic of PGMs with the accelerating consumption of limited PGMs nature resources. It is necessary to recover/recycle PGMs from a waste catalyst for both economic and...
Mon, 11/16/2020 - 22:19
Screening of terpenoids from Azadirachta indica against the Akt showed they are potent inhibitors of the protein. The screening revealed lupeol, a triterpenoid as the lead compound. Lupeol demonstrate surpassing inhibitory potential on Akt 2 than ipatasertib in in‐silico studies Terpenoids extract downregulate Akt mRNA and demonstrated anti‐Akt downstream signaling effects; anti‐inflammatory,...
Mon, 11/16/2020 - 22:18
Biochar has various ecological effects on heavy‐metal‐contaminated soils. Biochar can passivate the activity of heavy metals and improve environmental conditions for microbial growth. A greenhouse pot experiment was conducted to explore the diversity of microbes in red soil under cadmium (Cd) stress following the application of wheat straw biochar. The contaminant Cd was prepared at 2.5 mg kg‐1...
Mon, 11/16/2020 - 06:14
Author(s): Panneerselvam Karthikeyan, Shambanagouda. R. Marigoudar, Dhandapani Mohan, Krishna Venkatarama Sharma, M.V. Ramana Murthy Water quality standards are essential for regulation of contaminants in marine environment. Seawater quality criteria (SWQC) for arsenic (As), cadmium (Cd) and lead (Pb) have not been developed for India. The aim of this study is to derive the SWQC for the metals...
Sun, 11/15/2020 - 06:14
Author(s): Larissa Luiza dos Reis, Lays de Oliveira Gonçalves Alho, Cínthia Bruno de Abreu, Maria da Graça Gama Melão Metals may cause damage to the biota of contaminated environments. Moreover, using multiple endpoints in ecotoxicological studies is useful to better elucidate the mechanisms of toxicity of these compounds. Therefore, this study aimed to evaluate the effects of cadmium (Cd) and...
Sat, 11/14/2020 - 06:29
Author(s): Jelena Kulas, Dina Tucovic, Milica Zeljkovic, Dusanka Popovic, Aleksandra Popov Aleksandrov, Mirela Ukropina, Maja Cakic Milosevic, Jasmina Glamoclija, Milena Kataranovski, Ivana Mirkov Cadmium (Cd) is one of the most toxic environmental heavy metals to which the general population is exposed mainly via the oral route. Owing to its immunomodulatory potential, orally acquired Cd affects...
Sat, 11/14/2020 - 06:25
Author(s): Liqing Si, Jiatong Zhang, Azfar Hussain, Yong Qiao, Jinxing Zhou, Xiaoping Wang In recent years, heavy metal pollution has caused immeasurable harm to the environment. As an emerging technology, phytoremediation technology has gained a place in the treatment of heavy metal pollution with its unique advantages. This study analyzes the toxic effects of mulberry (Morus alba) seeds,...
Fri, 11/13/2020 - 06:16
Author(s): Masayo Hirao-Suzuki, Shuso Takeda, Genki Sakai, Michael P. Waalkes, Narumi Sugihara, Masufumi Takiguchi Cadmium (Cd) is recognized as a highly toxic heavy metal for humans in part because it is a multi-organ carcinogen. To clarify the mechanism of Cd carcinogenicity, we have established an experimental system using rat liver TRL1215 cells exposed to 2.5 μM Cd for 10 weeks and then...
Fri, 11/13/2020 - 06:14
Author(s): Xiaohui Xu, Zhan Song, Zan Li, Xiumei Liu, Yanwei Feng, Weijun Wang, Guohua Sun, Jianmin Yang A novel gill cell line from pearl gentian grouper (Epinephelus lanceolatus♂×Epinephelus fuscoguttatus♀, PGGG cell line) was established, its application in cadmium (Cd) toxicology was demonstrated in this study. Primary cultures and PGGG subcultures were carried out at 25 °C in Dulbecco’s...
Fri, 11/13/2020 - 04:03
Food is the major cadmium (Cd)-exposure pathway from agricultural soils to humans and other living entities and must be reduced in an effective way. A plant can select beneficial microbes, like plant-growth-promoting rhizobacteria (PGPR), depending upon the nature of root exudates in the rhizosphere, for its own benefits, such as plant growth promotion as well as protection from metal toxicity....
Thu, 11/12/2020 - 06:26
Soil application of biochars has been shown to effectively immobilize potentially toxic elements (PTEs). Soil water regime can also affect PTE availability. No previous studies have examined the interactive effect of biochars and soil water regime on Pb availability. Therefore, this study investigated the effect of high and low temperature (300 and 600 °C) biochars derived from cow manure (CB),...
Thu, 11/12/2020 - 02:04
Metal-contaminated mining soils pose serious environmental and health risks if not properly managed, especially in mountainous areas, which are more susceptible to perturbation. Currently, climate change is leading to more frequent and intense rain events, which cause flooding episodes, thereby altering soil redox equilibria and contaminants stability. We evaluated the potential release of Zn and...
Thu, 11/12/2020 - 02:03
Cloudiness, opalescence or a milky appearance in beverages is usually undesirable and lead the consumers to assume that the product is of lower quality. Many different types of formation and entry can lead to cloudiness and these causes can be divided into two major categories: beverage-specific, where the ingredients cause an interaction, and external influences such as process errors or...
Wed, 11/11/2020 - 22:16
Amphiphilic siderophores including amphibactins are the most abundant siderophores in oceans. Genes putatively encoding the amphibactin system were proposed in some bacteria and homologues of these genes are particulary abundant in multiple bacterial lineages inhabitant of low‐iron seawater. However, since no defective mutant strains in any of these genes were studied to date, their role in...
Wed, 11/11/2020 - 10:02
This study aimed to characterize in silico enterotoxigenic Escherichia coli F4- and F18-positive isolates (n = 90) causing swine postweaning diarrhea, including pathogenic potential, phylogenetic relationship, antimicrobial and biocide resistance, prophage content, and metal tolerance rates. F4 strains belonged mostly to the O149 and O6 serogroups and ST100 and ST48 sequence types (STs). F18...
Wed, 11/11/2020 - 08:02
A hitherto unknown composition is highlighted in the red and black inks preserved on ancient Egyptian papyri from the Roman period (circa 100 to 200 CE). Synchrotron-based macro–X-ray fluorescence (XRF) mapping brings to light the presence of iron (Fe) and lead (Pb) compounds in the majority of the red inks...
Tue, 11/10/2020 - 18:03
It is well-documented that lead (Pb) toxicity can affect almost all systems in living organisms. It can induce selective autophagy of mitochondria (mitophagy) by triggering reactive oxygen species production. Emerging evidence has suggested that Pb-induced autophagy can also be activated by the endoplasmic reticulum (ER) stress pathway. However, the interplay between ER stress and mitophagy...
Mon, 11/09/2020 - 22:20
The moisture sorption isotherms for oven dried mango were constructed gravimetrically at three different temperatures of 25°C, 30°C, and 35°C, and relative humidity ranging 8.3%–97.0%. The Guggenheim–Anderson–de Boer model was used to fit sorption data and constant equations determined using nonlinear regression analysis. The isotherms had J‐shaped curve that represents type III isotherms...
Sat, 11/07/2020 - 06:26
Lead (Pb) stress affects hormone-mediated responses (e.g., reproduction) in insects. In this study, the effects of Pb stress (12.5–50 mg Pb/kg in larval artificial diets) on the reproduction of the common cutworm Spodoptera litura (Lepidoptera: Noctuidae) were investigated after 7 generations. The results showed that Pb stress did not reduce the longevity of adult females, but 50 mg Pb/kg...
Sat, 11/07/2020 - 06:26
The Palaemonid shrimp Palaemon macrodactylus is widely distributed in coastal areas and estuaries which are easily contaminated by various pollutants. However, the responses of this species to environmental toxicants are not well described. In the present study, adult individuals of P. macrodactylus were exposed to gradient concentrations of Cadmium (Cd) to evaluate its acute toxic effects,...
Sat, 11/07/2020 - 04:03
Protoporphyrinogen oxidase (PPO, EC 1.3.3.4) is an important target for green agrochemical discovery. Herein, a novel N-phenylisoxazoline-thiadiazolo[3,4-a]pyridazine herbicidal active scaffold was designed by the scaffold hybridization strategy. Systematic structural optimization enabled the discovery of a series of derivatives with excellent weed control at 9.375–150 g ai/ha by the post-...
Fri, 11/06/2020 - 06:15
Author(s): Süreyya Oğuz Tümay, Vildan Şanko, Erhan Demirbas, Ahmet Şenocak Cadmium is one of the most toxic metal that accumulates in the human body via food chain, industrial/agricultural activies. It also has negative effects in organs such as the brain, liver and central nervous system. Therefore, International Agency for Research on Cancer is classified cadmium as “carcinogenic to humans” (...
Tue, 11/03/2020 - 06:29
Author(s): Jian-Ri Li, Yen-Chuan Ou, Chih-Cheng Wu, Jiaan-Der Wang, Shih-Yi Lin, Ya-Yu Wang, Wen-Ying Chen, Su-Lan Liao, Chun-Jung Chen Excessive accumulation of cadmium is known to cause nephrotoxicity by targeting renal proximal tubular epithelial cells. Studies showed an essential role of autophagy in cadmium-induced nephrotoxicity; however, its underlying mechanisms accompanied by autophagy...
Mon, 11/02/2020 - 22:13
BACKGROUND Research involved investigation of Pb, Cd and As concentrations in canned tuna, tuna steak, rainbow trout, smoked mackerel, Baltic and Atlantic cod as well as Atlantic salmon. The aim was to spot check the quality of the most commonly purchased type of fish which are available for sale in most common supermarket chains throughout the Poland as well as to determine potentially less...
Sun, 11/01/2020 - 22:16
In past ten years, microRNAs (miRNAs) have gained scientific attention due to their importance in the pathophysiology of allergic diseases and theirpotential as biomarkersin liquid biopsies. They act as master post‐transcriptional regulators that control most cellular processes. As one miRNA can target several mRNAs, often within the same pathway, dysregulated expression of miRNAs may alter...
Sun, 11/01/2020 - 22:16
Aim The anti‐leishmanial effect of the ‘carbohydrate fraction’ (designated as Ahf‐Car), isolated from an edible mushroom Astraeus hygrometricus, was evaluated against Leishmania donovani infection both in vitro and in vivo. Methods and Results Ahf‐Car induced the expression of inducible nitric oxide synthase 2 (iNOS2) and pro‐inflammatory cytokines like TNF‐α and IL‐12, with subsequent down‐...
Sun, 11/01/2020 - 03:02
Monoterpenoid alkaloids are well known for their broad and excellent biological activities, but their extremely low content and complex chemical structure limit their practical application. This study used the biosynthetic precursor genipin as a basic material to conduct a biomimetic synthesis of iridoid alkaloids. The structures of the iridoid alkaloids were characterized by 1H and 13C NMR...
Sat, 10/31/2020 - 22:16
The regulatory community is transitioning to the use of nonanimal methods for dermal sensitization assessments; however, some in vitro assays have limitations in their domain of applicability depending on the properties of chemicals being tested. This study explored the utility of epidermal sensitization assay (EpiSensA) to evaluate the sensitization potential of complex and/or “difficult to test...
Sat, 10/31/2020 - 22:16
Arsenic is a contaminant found in many foods and drinking water. Exposure to arsenic during development can cause improper neuronal progenitor cell development, differentiation, and function, while in vitro studies have determined that acute arsenic exposure to stem and progenitor cells reduced their ability to differentiate. In the current study, P19 mouse embryonal stem cells were exposed...
Fri, 10/30/2020 - 16:00
Hyperaccumulators are the preferred materials for phytoremediation. Sedum alfredii Hance is a cadmium (Cd) hyperaccumulator plant in China, although its detoxification mechanism remains unresolved. In our study, we cloned a gene belonging to the plant cadmium resistance (PCR) family, named SaPCR2, from the hyperaccumulating ecotype (HE) of S. alfredii. Sequence analysis indicated that SaPCR2...
Fri, 10/30/2020 - 00:02
Cancerous and non-cancerous cells secrete exosomes, a type of nanovesicle known to carry the molecular signature of the parent for intercellular communications. Exosomes secreted by tumor cells carry abnormal DNA, RNA, and protein molecules that reflect the cancerous status. DNA is the master molecule that ultimately affects the function of RNA and proteins. Aberrations in DNA can potentially...
Fri, 10/30/2020 - 00:01
Multidrug-resistant (MDR; resistance to &gt;3 antimicrobial classes) Salmonella enterica serovar I 4,[5],12:i:- strains were linked to a 2015 foodborne outbreak from pork. Strain USDA15WA-1, associated with the outbreak, harbors an MDR module and the metal tolerance element Salmonella Genomic Island 4 (SGI-4). Characterization of SGI-4 revealed that conjugational transfer of SGI-4 resulted in...
Thu, 10/29/2020 - 06:30
Author(s): Han Zhang, Shujia Ke, Shihong Zhang, Jingai Shao, Hanping Chen Cadmium (Cd) pollution in soil has attracted more attention recently for its high toxicity and easy accumulation in crops. This study aims to investigate the mechanisms governing the transport behavior of Cd, and to simulate and predict the long-term migration of Cd in different paddy soil layers. Therefore, a layer-by-...
Wed, 10/28/2020 - 22:17
Carotenoid isolated from the leaves of Spondias mombim; astaxanthin, β‐carotene‐15,15ʹ‐epoxide, and 7,7ʹ,8,8ʹ‐tetrahydro‐β‐β‐carotene demonstrate selective inhibition of XIAP by hydrophobic interactions within the domains of BIR2 and BIR3. The carotenoid isolates downregulate the expression of XIAP, Bcl‐2, COX‐2, and TNF‐α mRNAs, increase the activities of catalase, LDH, ALP, ALT enzymes, and...
Wed, 10/28/2020 - 18:03
Continuous occupational exposure to spent engine oil (SEO) poses physiological risks to humans, especially to automobile mechanics. This study investigated the physiological effects of SEO-contaminated soil in a male Wistar rat model. Animals were dermally exposed to soil contaminated with SEO for 120 consecutive days and compared with rats exposed to uncontaminated soil (negative control). Heavy...
Wed, 10/28/2020 - 10:04
ABSTRACT Cardiovascular disease (CVD) has been linked to animal-based diets, which are a major source of trimethylamine (TMA), a precursor of the proatherogenic compound trimethylamine-N-oxide (TMAO). Human gut bacteria in the genus Bilophila have genomic signatures for genetic code expansion that could enable them to metabolize both TMA and its precursors without production of TMAO. We uncovered...
Wed, 10/28/2020 - 06:14
Author(s): Xiaomin Gong, Danlian Huang, Yunguo Liu, Dongsheng Zou, Xi Hu, Lu Zhou, Zhibin Wu, Yang Yang, Zhihua Xiao Environment functional materials have been widely used, but whether their effects on the contaminated environment could facilitate phytoremediation is not yet well understood. In this study, starch stabilized nanoscale zerovalent iron (SN), multiwall carbon nanotubes (MW) and tea...
Tue, 10/27/2020 - 10:04
ABSTRACT The magnitude of the morbidity and mortality inflicted upon the global population in less than 1 year has driven the inescapable conclusion that the discovery and development of effective antiviral drugs for COVID-19 are urgent and should be prioritized. The antiviral drug discovery programs that emerged for HIV and hepatitis C virus have enabled technology and expertise to accelerate...
Tue, 10/27/2020 - 06:32
Author(s): Ederlan Magri, Alice Teresa Valduga, Itamar Luis Gonçalves, Julierme Zimmer Barbosa, Diego de Oliveira Rabel, Iohanna Moreira Nunes Ribeiro Menezes, Patrícia de Andrade Nascimento, Andrea Oliveira, Rodrigo Studart Corrêa, Antônio Carlos Vargas Motta Current legislation for Cd and Pb has been causing concern in the yerba mate production chain. An international survey was conducted to...
Tue, 10/27/2020 - 06:29
Author(s): Ting Zeng, Baohua Fang, Fenglin Huang, Li Dai, Zhi Tang, Jinglin Tian, Guodong Cao, Xuanlin Meng, Yuanchen Liu, Bo Lei, Minghua Lu, Zongwei Cai Cadmium is a toxic environmental pollutant that is readily absorbed by rice grains and poses serious threats to human health. The selection and breeding of rice varieties with low cadmium accumulation is one of the most economical and...
Mon, 10/26/2020 - 18:03
Several subsets of regulatory CD4+ T cells (CD4+ Tregs) have been described in peripheral blood and tumor microenvironment of breast cancer (BC) patients and may play a role in the progression of BC. High-risk human papilloma virus (HR-HPV) has a causal role in cervical, head, and neck tumors but the role of HR-HPV in evoking neoplasia in BC is still unclear. In this study we assessed the...
Sun, 10/25/2020 - 02:03
Assisted phytoremediation using amendments is a cost-effective and environmentally friendly approach to control soil pollution. However, amendment type, combination and application rate can influence process effectiveness. In the present study, the effect of the association of red mud and carbon-based amendments on the physicochemical properties of a former mine soil as well as the growth and...

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