Research Publications (Food Safety)

Nursery runoff may contain pesticide residues, which, if released off-site, could impair surrounding ecosystems. As a solution, nursery growers can retain runoff water on-site and recycle retained water to irrigate plants. However, concerns related to potential phytotoxicity caused by residual pesticides in recycled water can discourage growers from recycling water.

The fungal phosphatidylserine (PS) synthase, a membrane protein encoded by the CHO1 gene, is a potential drug target for pathogenic fungi, such as Candida albicans. However, both substrate-binding sites of C. albicans Cho1 have not been characterized. Cho1 has two substrates: cytidyldiphosphate-diacylglycerol (CDP-DAG) and serine. Previous studies identified a conserved CDP-alcohol phosphotransferase (CAPT) binding motif, which is present within Cho1.

Author(s): Pilaipan Chaikhan, Yuthapong Udnan, Richmond J. Ampiah-Bonney, Wipharat Chuachuad Chaiyasith

β-defensins are antimicrobial peptides presenting in vertebrate animals. They participate in innate immunity, but little is known about them in reptiles, including snakes. Although several β-defensin genes were described in Brazilian snakes, their function is still unknown.

Journal of Separation Science, Accepted Article. Hydroxyl polycyclic aromatic hydrocarbons are considered active mutagenic and carcinogenic substances and are found in extremely low levels (ng/g) in biological samples. As a result, their determination in urine and blood samples is challenging, and a sensitive and effective method for the analysis of trace hydroxyl polycyclic aromatic hydrocarbons in complex biological matrices is required.

Environmental Microbiology, EarlyView. Cadmium is a highly toxic heavy metal that causes many harmful effects on human health and ecosystems. Metal chelation-based techniques have become a common approach for the treatment of metal poisoning and also for the remediation of metal contamination. Phosphate, an essential nutrient required for key cellular functions, has been supposed to be effective in reducing cadmium bioavailability, possibly through its chelating potential.

Antimicrobial peptides (AMPs) constitute a broad range of bioactive compounds in diverse organisms, including fish. They are effector molecules for the innate immune response, against pathogens, tissue damage and infections. Still, AMPs from African Catfish, Clarias gariepinus, skin mucus are largely unexplored despite their possible therapeutic role in combating antimicrobial resistance.

To improve the insecticidal activity of (+)-nootkatone, a series of 42 (+)-nootkatone thioethers containing 1,3,4-oxadiazole/thiadiazole moieties were prepared to evaluate their insecticidal activities against Mythimna separata Walker, Myzus persicae Sulzer, and Plutella xylostella Linnaeus.

The discovery of new antimicrobials is the prime target in the fight against antimicrobial resistance. The continuous search for new lead compounds from bacteria of untapped and extreme ecosystems such as mangroves is currently being undertaken. This study describes the metabolite profiling of the Streptomyces euryhalinus culture extract. Previously, Streptomyces euryhalinus was isolated from the mangrove forest of Indian Sundarbans as a novel microorganism.

International Journal of Food Science & Technology, Accepted Article. The effect of microwave roasting parameters (300, 450 and 600 W; 5, 10 and 15 min) on acrylamide content in sorghum grain was determined using High Pressure Liquid Chromatography (HPLC)-photo diode array (PDA) detector coupled with C-18 column.

Author(s): Deepak Kukkar, Preeti Kukkar, Sherif A. Younis, Ki-Hyun Kim

Author(s): Elahe Abedi, Kiana Pourmohammadi, Mehran Sayadi

Author(s): Mingli Wei, Yuan Li, Bowei Yu, Lei Liu, Qiang Xue, Yanjun Du

Author(s): Yun Zhang, Ming Yan, Weiyan Shan, Tao Zhang, Yunchen Shen, Ruirong Zhu, Jian Fang, Hongjiao Mao

Despite the enormous burden of Alzheimer’s disease and related dementias (ADRD) on patients, caregivers, and society, only a few treatments with limited efficacy are currently available. While drug development conventionally focuses on disease-associated proteins, RNA has recently been shown to be druggable for therapeutic purposes as well.

Biosurfactants derived from different microbes are an alternative to chemical surfactants, which have broad applications in food, oil, biodegradation, cosmetic, agriculture, pesticide and medicine/pharmaceutical industries. This is due to their environmentally friendly, biocompatible, biodegradable, effectiveness to work under various environmental conditions and non-toxic nature.

Author(s): Manlu Wang, Juan He, Jin Luo, Jing Hu, Xiandeng Hou

Maintaining membrane integrity is of paramount importance to the survival of bacteria as the membrane is the site of multiple crucial cellular processes including energy generation, nutrient uptake and antimicrobial efflux. The DedA family of integral membrane proteins are widespread in bacteria and are associated with maintaining the integrity of the membrane. In addition, DedA proteins have been linked to resistance to multiple classes of antimicrobials in various microorganisms.

Furan is a volatile compound formed during the thermal processing of foods. Chronic exposure has been shown to cause cholangiocarcinoma and hepatocellular tumors in rodent models. We conducted a 90 day subchronic study in Fisher 344 rats exposed to various doses by gavage to determine the NOAEL. Previous reports have outlined changes in the liver using gross necropsy examination, histopathology, clinical biochemistry, hematology, immunohistochemistry, and toxicogenomics.

Author(s): R. Paranthaman, J.A. Moses, C. Anandharamakrishnan

Author(s): Rushali Girame, T.P. Ahammed Shabeer, Bappa Ghosh, Sandip Hingmire, Ramesh Natarajan, Pradyumn Narayan Dubey

Author(s): Yangliu Wu, Quanshun An, Dong Li, Lu Kang, Chunran Zhou, Jingbang Zhang, Canping Pan

Author(s): Yang Yue, Ping Deng, Heng Xiao, Miduo Tan, Hui Wang, Li Tian, Jia Xie, Mengyan Chen, Yan Luo, Liting Wang, Yidan Liang, Huifeng Pi, Zhou Zhou, Zhengping Yu

by Barbara K. Linnehan, Forrest M. Gomez, Sharon M. Huston, Adonia Hsu, Ryan Takeshita, Kathleen M. Colegrove, Craig A. Harms, Ashley Barratclough, Alissa C. Deming, Teri K. Rowles, Whitney B. Musser, Eric S. Zolman, Randall S. Wells, Eric D. Jensen, Lori H. Schwacke, Cynthia R. Smith