Chemical contaminants

Thu, 02/25/2021 - 02:02
Stormwater harvesting and reuse is an attractive option to lower the demand placed on other sources of water supply. However, it contains a wide range of pollutants that need to be removed before it can be reused or even discharged to the waterways and receiving waters. An experimental protocol to estimate the efficiency of a soil-based-filter medium for the treatment of stormwater pollutants...
Wed, 02/24/2021 - 10:03
ABSTRACT Most antimicrobials currently in the clinical pipeline are modifications of existing classes of antibiotics and are considered short-term solutions due to the emergence of resistance. Pseudomonas aeruginosa represents a major challenge for new antimicrobial drug discovery due to its versatile lifestyle, ability to develop resistance to most antibiotic classes, and capacity to form robust...
Wed, 02/24/2021 - 10:03
ABSTRACT Antibiotic-resistant bacteria rapidly spread in clinical and natural environments and challenge our modern lifestyle. A major component of defense against antibiotics in Gram-negative bacteria is a drug permeation barrier created by active efflux across the outer membrane. We identified molecular determinants defining the propensity of small peptidomimetic molecules to avoid and inhibit...
Wed, 02/24/2021 - 10:03
ABSTRACT Nucleoside analogs are mainstays of antiviral therapy. Although resistance to these drugs hinders their use, understanding resistance can illuminate mechanisms of the drugs and their targets. Certain nucleoside analogs, such as ganciclovir (GCV), a leading therapy for human cytomegalovirus (HCMV), contain the equivalent of a 3'-hydoxyl moiety, yet their triphosphates can terminate genome...
Wed, 02/24/2021 - 06:09
Author(s): Emel Oz The formations of polycyclic aromatic hydrocarbons (PAHs) and heterocyclic aromatic amines (HAAs) in barbecued meatballs formulated with different animal fats [beef intermuscular and/or sheep tail (ST)] were investigated. Meatballs were also analyzed in terms of some qualitative and quantitative properties. From perspective of nutrition, meatballs formulated with ST fat at...
Wed, 02/24/2021 - 00:00
Bisphenol S (BPS) is used as an alternative plasticizer to Bisphenol A (BPA), despite limited knowledge of potential adverse effects. BPA exhibits endocrine disrupting effects during development. This article focuses on the impact of bisphenols during oocyte maturation. Connexins (Cx) are gap junctional proteins that may be affected by bisphenols, providing insight into their mechanism during...
Tue, 02/23/2021 - 08:03
To overcome the severe toxicity and blind absorption zone of conventional lead-based shielding materials for X-rays in the 70–90 keV range, the lead-free multilayered polymer composites were designed and fabricated. The effects of the direction of incidence of the X-rays and number of layers as well as layer thickness ratio of the (tungsten/ethylene-octene copolymer)/(bismuth/ethylene-octene...
Tue, 02/23/2021 - 08:03
Acetogenic bacteria use cellular redox energy to convert CO2 to acetate using the Wood–Ljungdahl (WL) pathway. Such redox energy can be derived from electrons generated from H2 as well as from inorganic materials, such as photoresponsive semiconductors. We have developed a nanoparticle-microbe hybrid system in which chemically synthesized cadmium sulfide...
Tue, 02/23/2021 - 06:14
Author(s): Xia Zhao, Shengchen Wang, Xiaojing Li, Honggui Liu, Shiwen Xu Cadmium (Cd) is one common environmental pollutant with systemic toxicity. Lipoxin A4 (LXA4) can regulate transforming growth factor-β (TGF-β) pathway and alleviate tissue injury via binding to formyl peptide receptor 2 (FPR2). The activation of nuclear factor-κB (NF-κB) pathway can promote the occurence of necroptosis....
Tue, 02/23/2021 - 02:02
Abstract Field-scale experiments were conducted to assess biochar’s ability with and without supplements to sequester heavy metals of lead (Pb2+) and zinc (Zn2+) from stream water contaminated by abandoned mines. The study was conducted at the Frongoch mine watercourse site in central Wales for 1104 h (46 days). The methods employed include pyrolysis of waste Leylandii feedstocks at 700 °C and...
Mon, 02/22/2021 - 06:10
Author(s): Yiwen Sun, Jialiang Huang, Lianxin Shan, Shuting Fan, Zexuan Zhu, Xudong Liu Quantitative analysis of complex mixtures is a great challenge for spectral analysis. Bisphenol A (BpA) is a chemical predominantly used in manufacturing and is being replaced by other analogs due to its potential toxicity. Reliability methods is hence crucial for identification and quantification of bisphenol...
Mon, 02/22/2021 - 06:10
Author(s): Wenwen Deng, Anqi Huang, Qutong Zheng, Long Yu, Xiao Li, Hankun Hu, Yuxiu Xiao A novel density-tunable liquid-phase microextraction (DT-LPME) system was developed with high-density deep eutectic solvents (DESs) as extractant and low-density organic solvents as emulsifier and density regulator. DES-rich phase was induced to form in the bottom or in the top by adjusting the emulsifier...
Mon, 02/22/2021 - 06:10
Author(s): Xu Pang, Xiuhua Liu, Liangrui Peng, Zhijun Chen, Jing Qiu, Xin Su, Changyuan Yu, Jiguang Zhang, Rui Weng Increasing pesticide contamination in foods of animal origin has made the wide-scope multi-residue analysis of pesticides an international concern. In this study, a sensitive and reliable multi-residue pesticide analysis method for beef was developed with the use of 129 pesticides...
Mon, 02/22/2021 - 06:09
Author(s): Kaihang Mi, Xi Chen, Kaiyuan Lu, Yujie Zhu, Meng Zhang, Hui Yang, Wenzhi Wei, Yingying Zhang Bisphenol A (BPA), an endocrine disruptor, exist in almost all waters. In the present study, we expose adult male Gobiocypris rarus rare minnow to 15 μg/L BPA to study the effect BPA on fish hepatic lipid metabolism. Following 1, 3 and 5 weeks exposure, the liver tissue of rare minnow was...
Sun, 02/21/2021 - 06:14
Author(s): T.R. Reshmitha, P. Nisha Acrylamide (ACR), a carcinogen and neurotoxin formed in carbohydrate-rich high temperature processed foods, undergo epoxidation in cells to form more toxic metabolite glycidamide (GLY). The present study investigated antioxidant potential of lycopene (LYC) against ACR and GLY induced toxicity in human liver cell line (HepG2). The treatment of HepG2 cells with...
Sun, 02/21/2021 - 06:11
Author(s): Ju Tang, Weixia Duan, Ping Deng, Huijuan Li, Cong Liu, Yu Duan, Min Feng, Shangcheng Xu Cadmium (Cd) is a ubiquitous environmental and occupational pollutant that is considered a high-risk factor for neurodegenerative diseases. However, the mechanism underlying Cd-induced neurotoxicity has not been fully elucidated. Abnormal mitochondrial distribution and excessive mitochondrial...
Sun, 02/21/2021 - 04:02
Triglyceride (TG) is a class of neutral lipids, which functions as an energy storage depot and is important for cellular growth, metabolism, and function. The composition and content of TG molecular species are crucial factors for nutritional aspects in food chemistry and are directly associated with several diseases, including atherosclerosis, diabetes, obesity, stroke, etc. As a result of the...
Sat, 02/20/2021 - 22:09
Journal of the Science of Food and Agriculture, Accepted Article. Lead (Pb2+) is one of the most toxic heavy metals, which can be found in various quantities in the environment. The five native probiotic bacteria and inulin were used to assess in vitro lead nitrate and lead acetate binding capacities and removal potentials.
Sat, 02/20/2021 - 08:06
by Kimia Kardani, Azam Bolhassani Among various delivery systems for vaccine and drug delivery, cell-penetrating peptides (CPPs) have been known as a potent delivery system because of their capability to penetrate cell membranes and deliver some types of cargoes into cells. Several CPPs were found in the proteome of viruses such as Tat originated from human immunodeficiency virus-1 (HIV-1), and...
Sat, 02/20/2021 - 06:31
Author(s): Yi Zhou, Wenlong Jiang, Xinyu Guo, Yun Zhao, Baoqiang Xu, Jiarong Li, Bin Yang Noble lead, which is produced by the reduction smelting of lead anode slime, contains copious rare and precious metals. The vacuum distillation procedure for processing noble lead exhibits the advantages of efficiency and simplicity, and has been industrialized in most of China’s lead, copper and precious...
Sat, 02/20/2021 - 06:30
Author(s): Teh Sabariah Binti Abd Manan, Taimur Khan, Wan Hanna Melini Wan Mohtar, Salmia Beddu, Sobia Qazi, Zohreh Sheikh Khozani, Nur Liyana Mohd Kamal, Ariyanti Sarwono, Hisyam Jusoh, Saba Yavari, Siti Fatimah Zaharah Mustafa, Zarimah Hanafiah, Hayyiratul Fatimah Mohd Zaid, Affiani Machmudah, Mohamed Hasnain Isa, Amirrudin Ahmad, Abdulnoor A.J. Ghanim
Sat, 02/20/2021 - 06:24
Author(s): Jinfeng Ran, Lingxue Zhang, Jianmei Yao, Shasha Wang, Ping Liang, Nan Dong Cucurbit[7]uril (Q[7]) was first used as a dispersant sorbent material in a matrix solid-phase dispersion for the simultaneous extraction of four quaternary ammonium pesticides from vegetables before analysis using high-performance liquid chromatography with UV detection. Q[7] exhibited a better selectivity and...
Sat, 02/20/2021 - 02:03
This study focuses on heavy metal contamination in soils due to recreational shooting within the Tonto National Forest, Arizona. The main research questions are: (1) Have some soils within the Tonto National Forest (NF) been contaminated with lead (Pb) due to recreational shooting? (2) How far downslope have the soils been contaminated? Soils in permitted shooting areas were tested for lead (Pb...
Fri, 02/19/2021 - 22:13
Journal of Separation Science, Accepted Article. In this study, a lab‐made Parallel‐Single Drop Microextraction methodology using the magnetic ionic liquid trihexyltetradecylphosphonium tetrachloromanganate (II) as extraction solvent was developed to determine the pesticides tebuconazole, pendimethalin, dichlorodiphenyltrichloroethane, and dichlorodiphenyldichloroethylene in human urine samples....
Fri, 02/19/2021 - 22:13
Journal of Separation Science, Accepted Article. In this paper, we propose a novel micro‐solid‐phase extraction and elution technique, which we called the thin‐layer solid‐phase extraction–liquid film elution technique. The thin‐layer solid‐phase extraction phase is an octadecylsilylated sol‐gel coated porous silica thin film prepared on the outer wall of a test tube, which has a larger surface...
Fri, 02/19/2021 - 16:00
Rice, a staple crop for nearly half the planet’s population, tends to absorb and accumulate excessive cadmium (Cd) when grown in Cd-contaminated fields. Low levels of Cd can degrade the quality of rice grains, while high levels can inhibit the growth of rice plants. There is genotypic diversity in Cd distribution and Cd tolerance in different rice varieties, but their underlying genetic...
Fri, 02/19/2021 - 08:03
Acid-sensing ion channels (ASICs) are expressed in the nervous system, activated by acidosis, and implicated in pain pathways. Mambalgins are peptide inhibitors of ASIC1 and analgesic in rodents via inhibition of centrally expressed ASIC1a and peripheral ASIC1b. This activity has generated interest in mambalgins as potential therapeutics. However, most mechanism...
Fri, 02/19/2021 - 06:10
Author(s): Hongxia Tang, Lin Ma, Jiaqing Huang, Yubo Li, Zehui Liu, Dianying Meng, Guangyue Wen, Maofeng Dong, Weimin Wang, Li Zhao A reliable and simple modified QuEChERS method with UPLC-MS/MS was developed for the simultaneous determination of six pesticides (dimethomorph, imidaclothiz, lufenuron, methoxyfenozide, pyridaben, spinetoram) and their metabolites in pak choi. Method validation...
Fri, 02/19/2021 - 02:04
Cadmium (Cd) in soil–plant system can abridge plant growth by initiating alterations in root zones. Hydroponics and rhizoboxes are useful techniques to monitor plant responses against various natural and/or induced metal stresses. However, soil based studies are considered more appropriate in order to devise efficient food safety and remediation strategies. The present research evaluated the Cd-...
Fri, 02/19/2021 - 02:03
Jumping ability determines the likelihood of survival and reproduction of amphibians. To study the toxic effect of lead (Pb) on the jumping ability of amphibians, Pelophylax nigromaculata were treated with 0, 1 and 10 mg/L Pb for 10 days and 20 days each. The results showed that for both treatment time (10 days and 20 days), compared to the control group, the 1 mg/L Pb treatment had no...
Thu, 02/18/2021 - 16:00
New anti-infective approaches are urgently needed to control multidrug-resistant (MDR) pathogens, such as methicillin-resistant Staphylococcus aureus (MRSA). Sortase A (SrtA) is a membrane-bound cysteine transpeptidase that plays an essential role in the catalysis of covalent anchoring of surface proteins to the cell wall of Staphylococcus aureus (S. aureus). The present study reports...
Thu, 02/18/2021 - 10:02
Zinc is an essential micronutrient for mycobacteria, and its depletion induces multiple adaptive changes in cellular physiology, the most remarkable of which are remodeling and hibernation of ribosomes. Ribosome remodeling, induced upon relatively moderate depletion of zinc, involves replacement of multiple ribosomal proteins containing the zinc-binding CXXC motif (called C+ r proteins) by their...
Thu, 02/18/2021 - 10:02
Schistosomiasis poses a serious threat to human health and remains a major tropical and parasitic disease in more than 70 countries. Praziquantel (PZQ) has been the primary treatment for schistosomiasis for nearly 4 decades. However, its efficacy against migratory-stage schistosomula is limited. Radicicol (RAD), a β-resorcylic acid lactone derived from Paecilomyces sp. strain SC0924, was...
Thu, 02/18/2021 - 06:29
Author(s): Ziyang Luo, Hanying Duan, Yuncheng Yang, Wentao Zhang, Hosahalli S. Ramaswamy, Weibin Bai, Chao Wang Cadmium (Cd) ranks seventh in the World Health Organization (WHO) priority list of hazardous toxic substances. In this study, a high-pressure extraction (HPE) method was explored for Cd decontamination in rice, and the process was compared with the traditional washing method. Optimal...
Thu, 02/18/2021 - 06:26
Author(s): Lucas Suchecki Barnet, Dirce Pozebon, Valderi L. Dressler, Daiane Cioato A methodology for As speciation in rice using liquid chromatography-inductively coupled plasma mass spectrometry (LC-ICP-MS) was optimised and validated. Chromatographic separation and elution of As(III), DMA(V) (dimethylarsenic acid), MMA(V) (monomethylarsenic acid) and As(V) were achieved in less than 8 min...
Thu, 02/18/2021 - 04:02
Effective strategies are needed to deal with invasive fungal infections caused by drug-resistant fungi. Previously, we designed a series of antifungal benzocyclane derivatives based on the drug repurposing of haloperidol. Herein, further structural optimization and antifungal mechanism studies were performed, leading to the discovery of new piperidol derivative B2 with improved synergistic...
Thu, 02/18/2021 - 02:02
Cadmium (Cd) is considered one of the heavy metals disturbing plant biophysiological functions. The potential role of phosphorus (P) nutrition in the attenuation of Cd effects on photosynthetic efficiency, plant growth, and cadmium uptake has been investigated in hydroponically grown tomato. Two P nutrition regimes (P15: 15 mg l-1; P30: 30 mg l-1) were assessed in the presence or absence of Cd (...
Thu, 02/18/2021 - 02:02
Removal of polycyclic aromatic hydrocarbons (PAHs) from wastewater treatment sludge with appropriate technologies is of great importance for nature and public health. UV technology is one of the most frequently used methods for the removal of PAHs. While various photodegradation applications with UV-C (ultraviolet-C) light and photocatalysts can be performed to remove these compounds, a large...
Wed, 02/17/2021 - 06:10
Author(s): Hongyan Xu, Minggang Zheng, Ling Wang, Wucai Zhao, Yi Hua, Lidan Fang, Aifeng Liu, Zongshan Zhao Tetrabromobisphenol A (TBBPA), halogenated carbazole (HCZ), and their analogs are the emerging pollutants invading the marine environment. So far, a few methods have been reported for the simultaneous analysis of these pollutants due to their large polarity difference. In this study, an...
Tue, 02/16/2021 - 06:24
Author(s): Yuanyuan Fang, Lili Lu, Yuan Liang, Dongjie Peng, Michael Aschner, Yueming Jiang Lead is a heavy metal pollutant that is widely present in the environment. It affects every organ system, yet the nervous system appears to be the most sensitive and primary target. Although many countries have made significant strides in controlling Pb pollution, Pb poisoning continuous to be a major...
Tue, 02/16/2021 - 02:03
In recent years Melamine is upgraded as a type three carcinogen. It is a sorry fact that still; people are in the fantasy mode and abaft the melamine tableware as they are a good piece of decorative material which sets dining an opulent look. The present study focuses on the determination of melamine leaching from melamine tablewares. The food stimulants culled for this study are conventional...
Tue, 02/16/2021 - 02:03
An arginine–glucose mixture (1:2 mol ratio) with pH 9 was heated at 53–100 °C for 10–350 min, and the effects of process parameters were determined during the Maillard reaction (MR). The heating temperature and time were selected as process conditions and were studied with central composite design. The model system was tested based on the values obtained from antioxidant capacity, browning...
Tue, 02/16/2021 - 02:03
The furan levels in commercial coffee product samples (17 instant coffees, 12 mixed coffee, 8 canned coffee) were 49–2155, 10–201 and 15–209 ng/g, respectively. Since thermal degradation/rearrangement of carbohydrates is the main source of furan, the concentrations of furan and monosaccharides (mannose, rhamnose, glucose, galactose and arabinose) were analysed in 26 green and roasted coffee bean...
Tue, 02/16/2021 - 02:03
Air samples were collected around industrial parks in Jiangsu, China, to allow the concentrations, profiles, and risk assessment of polybrominated dibenzo-p-dioxins and dibenzofurans (PBDD/Fs), polychlorinated naphthalenes (PCNs), and metals to be investigated. The concentrations of ΣPBDD/Fs and ΣPCNs were 1324.26–2080.98 fg/m3 (11.35–42.57 fg I-TEQ/m3) and 10,404.9–29,322.9 fg/m3 (1.32–7.19 fg I...
Mon, 02/15/2021 - 06:11
Author(s): Jingzeng Cai, Haoyue Guan, Xing Jiao, Jie Yang, Xiaoming Chen, Haoran Zhang, Yingying Zheng, Yue Zhu, Qi Liu, Ziwei Zhang Cadmium (Cd) chloride, as widely distributed toxic environmental pollutants by using in industry, severely imperils animal and human health. Pyroptosis is a Cas1-dependent pro-inflammatory programmed cell death and involves in various types of diseases. Nevertheless...
Mon, 02/15/2021 - 02:03
This study provides data on the characteristic levels, spatial patterns, sources, and risk of n-alkanes (AHs) [octane, n-C8, to tetracontane, n-C40] and polycyclic aromatic hydrocarbons (PAHs) in surficial sediments from the Escravos River Basin (ERB), Nigeria. The n-alkane and PAH concentrations in sediments were quantified by chromatographic methods. The concentrations of AHs and PAHs in the...
Sun, 02/14/2021 - 06:10
Author(s): Ru Chen, Xiaomin Xue, Guiping Wang, Jinzheng Wang The presence of pesticide residues in apples raises serious health concerns. In this study, a novel, sensitive, high-performance method was developed to simultaneously analyze the residues of 14 pesticides in apples using modified QuEChERS sample pretreatment coupled with ultra-performance liquid chromatography-tandem mass spectrometry...
Sat, 02/13/2021 - 22:28
Seafood is capable of bioaccumulating heavy metals (HM), making it a potentially major dietary source of HM for humans. Presently, little data exists on seafood from the eastern‐most boundary of the Mediterranean Sea. This study aims to provide exposure insight of the Israeli population to HM through the consumption of locally caught seafood by assessing the levels of arsenic, mercury, cadmium,...
Sat, 02/13/2021 - 06:24
Author(s): Chaoyue Yang, Bo Nan, Haiqing Ye, Haiyang Yan, Minghua Wang, Yuan Yuan Acrylamide (AA), an important by-product of the Maillard reaction, has been reported to be genotoxic and carcinogenic. The present study employed miRNAs to investigate the toxic mechanism of AA and their role against AA toxicity. Deep sequencing of small RNA libraries was performed and miR-193b-5p was applied for...
Sat, 02/13/2021 - 06:24
Author(s): Yumi Abiko, Yusuke Katayama, Masahiro Akiyama, Yoshito Kumagai Garlic (Allium sativum L.) contains numerous sulfur compounds. We have previously found that reactive sulfur species such as glutathione persulfide, glutathione polysulfide, protein-bound persulfides, and hydrogen sulfide can bind to methylmercury to give bismethylmercury sulfide, which is less toxic than methylmercury. It...

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