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Food and Chemical Toxicology

Mon, 08/12/2019 - 01:03
Publication date: Available online 10 August 2019 Food and Chemical ToxicologyAuthor(s): Luísa Freire, Marianna M. Furtado, Tatiane M. Guerreiro, Juliana S. da Graça, Beatriz S. da Silva, Diogo N. Oliveira, Rodrigo R. Catharino, Anderson S. Sant’AnaAbstractYeasts are able to reduce the levels of ochratoxin A in fermentative processes; and, through their enzymatic complex, these micro-organisms...
Mon, 08/05/2019 - 01:05
Publication date: Available online 28 July 2019 Food and Chemical ToxicologyAuthor(s): L. Camacho, S.M. Lewis, M.M. Vanlandingham, G.R. Olson, K.J. Davis, R.E. Patton, N.C. Twaddle, D.R. Doerge, M.I. Churchwell, M.S. Bryant, F.M. McLellen, K. Woodling, R.P. Felton, M.P. Maisha, B.E. Juliar, G. Gamboa da Costa, K.B. DelclosAbstractWe report the data from the guideline-compliant two-year toxicology...
Mon, 08/05/2019 - 01:05
Publication date: Available online 29 July 2019 Food and Chemical ToxicologyAuthor(s): A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A.D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D.C. Liebler, D. O'Brien, A. Patel, T.M. Penning
Mon, 08/05/2019 - 01:05
Publication date: Available online 31 July 2019 Food and Chemical ToxicologyAuthor(s): Shuyuan Zhang, Shuailin Hao, Zhiyu Qiu, Ya Wang, Yuqin Zhao, Youhang Li, Wen Gao, Yan Wu, Chang Liu, Xingzhi Xu, Hailong WangAbstractCadmium (Cd) is a dispensable element for the human body and is usually considered a carcinogen. Occupational and environmental Cd exposure leads to sustained cellular...
Mon, 08/05/2019 - 01:05
Publication date: Available online 2 August 2019 Food and Chemical ToxicologyAuthor(s): Shruti Shukla, Jong Suk Lee, Vivek K. Bajpai, Imran Khan, Yun Suk Huh, Young-Kyu Han, Myunghee KimAbstractThe present study aimed to develop a consortium of nutritive fermented food products, supplemented with phytochemicals, with reduced toxicological contents. We developed new flavored Doenjang products (...
Mon, 08/05/2019 - 01:05
Publication date: Available online 4 August 2019 Food and Chemical ToxicologyAuthor(s): Yanwen Xue, Fang Huang, Rongxue Tang, Qingsheng Fan, Bing Zhang, Zhenjiang Xu, Xiaoming Sun, Zheng RuanAbstractChronic exposure to cadmium (Cd) causes remarkable damage to the liver and gastrointestinal tract. Previous studies have revealed that chlorogenic acid (CGA) could improve the intestinal barrier...
Mon, 08/05/2019 - 01:05
Publication date: November 2019 Food and Chemical Toxicology, Volume 133Author(s): Grazia Barone, Arianna Storelli, Nicoletta C. Quaglia, Angela Dambrosio, Rita Garofalo, Roberta Chiumarulo, Maria M. StorelliAbstractIn order to investigate PCB and PCDD/F concentrations and potential human health risk a study has been conducted in meat samples (beef, pork, chicken and turkey) purchased from...
Fri, 08/02/2019 - 01:03
Publication date: October 2019 Food and Chemical Toxicology, Volume 132Author(s): Neus González, Josep Calderón, Antoni Rúbies, Isabel Timoner, Victòria Castell, José L. Domingo, Martí NadalAbstractIn 2017, a monitoring study was conducted in Catalonia (Spain) to analyse, in widely consumed foodstuffs, the concentrations of arsenic (As), cadmium (Cd), mercury (Hg) and lead (Pb), as well as those...
Tue, 07/30/2019 - 01:05
Publication date: Available online 29 July 2019 Food and Chemical ToxicologyAuthor(s): Xuan Yang, Yijia Li, Lirong Zheng, Xiaoyun He, Yunbo Luo, Kunlun Huang, Wentao XuAbstractThe incidence of kidney disease has increased rapidly in recent years. One major possible reason for this increase in nephrosis is from foodborne toxins. Since the mechanism of how foodborne toxins are involved in the...
Wed, 07/24/2019 - 01:03
Publication date: Available online 22 July 2019 Food and Chemical ToxicologyAuthor(s): Lara Ferreira Azevedo, Carlos Roberto Porto Dechandt, Cecília Cristina de Souza Rocha, Maria Fernanda Hornos Carneiro, Luciane Carla Alberici, Fernando BarbosaAbstractThe present study evaluates the effects of low-level long-term exposure to bisphenol A (BPA) and bisphenol S (BPS) on serum biochemical markers,...
Wed, 07/24/2019 - 01:03
Publication date: Available online 22 July 2019 Food and Chemical ToxicologyAuthor(s): Sheraz Ahmed Bhatti, Muhammad Zargham Khan, Muhammad Kashif Saleemi, Zahoor Ul Hassan, Aisha KhatoonAbstractOchratoxin A (OA), the secondary metabolite of certain Aspergillus and Penicillium species, is one of the potent biological immune-suppressor. The present study was designed to explore the in-vivo...
Tue, 07/16/2019 - 01:05
Publication date: Available online 12 July 2019 Food and Chemical ToxicologyAuthor(s): Giovanni Pallio, Antonio Micali, Salvatore Benvenga, Alessandro Antonelli, Herbert R. Marini, Domenico Puzzolo, Vincenzo Macaione, Vincenzo Trichilo, Giuseppe Santoro, Natasha Irrera, Francesco Squadrito, Domenica Altavilla, Letteria MinutoliAbstractCadmium (Cd) induces functional and morphological changes in...
Sat, 07/13/2019 - 01:03
Publication date: Available online 11 July 2019 Food and Chemical ToxicologyAuthor(s): Katarzyna Palus, Kazimierz Obremski, Michał Bulc, Jarosław CałkaAbstractThe present study was designed to assess the influence of acrylamide supplementation, in tolerable daily intake (TDI) dose and a dose ten times higher than TDI, on the neurochemical phenotype of the ENS neurons and synthesis of...
Thu, 07/11/2019 - 01:05
Publication date: Available online 10 July 2019 Food and Chemical ToxicologyAuthor(s): Bessem Mornagui, Raja Rezg, Cendrine Repond, Luc PellerinAbstractBisphenol A has been restricted in a large variety of products. Bisphenol S (BPS) is its major substitute. Yet, the impacts of BPS on the central nervous system are unknown, especially in vulnerable populations like children. The aim of this study...
Wed, 06/26/2019 - 01:12
Publication date: September 2019 Food and Chemical Toxicology, Volume 131Author(s): Hans Steinkellner, Marco Binaglia, Chiara Dall'Asta, Arno C. Gutleb, Manfred Metzler, Isabelle P. Oswald, Dominique Parent-Massin, Jan AlexanderAbstractThis paper describes a methodology for hazard assessment of groups of related substances for which toxicity data are insufficient, and which utilises, next to...
Sun, 06/23/2019 - 01:15
Publication date: Available online 21 June 2019 Food and Chemical ToxicologyAuthor(s): Hasan Badibostan, Javad Feizy, Bahram Daraei, Shahram Shoeibi, Seyed Hossein Rajabnejad, Javad Asili, Seyedeh Faezeh Taghizadeh, John P. Giesyh, Gholamreza KarimiAbstractTwenty-seven samples of infant formulae and follow-on formulae and fifteen samples of baby food from Iranian markets were analyzed for...
Wed, 06/19/2019 - 01:16
Publication date: Available online 17 June 2019 Food and Chemical ToxicologyAuthor(s): Qin Zhao, Zhao-Si Yang, San-Jie Cao, Yung-Fu Chang, Yu-Qin Cao, Jia-Bing Li, Zi-Xuan Yao, Yi-Ping Wen, Xiao-Bo Huang, Rui Wu, Qi-Gui Yan, Yong Huang, Xiao-Ping Ma, Xin-Feng Han, Yinglong WuAbstractCadmium and aflatoxin B1 (AFB1) are both common and widespread pollutants in food and feed. There are several...
Fri, 06/14/2019 - 01:12
Publication date: Available online 13 June 2019 Food and Chemical ToxicologyAuthor(s): Giacomo Russo, Francesco Barbato, Damiano Gustavo Mita, Lucia GrumettoAbstractBisphenol A and its analogues belong to the class of endocrine disrupting chemicals, massively employed by industries to produce polycarbonate and epoxy resins, designed to be in direct contact with foodstuffs. Their leaching from the...
Mon, 06/10/2019 - 01:12
Publication date: Available online 8 June 2019 Food and Chemical ToxicologyAuthor(s): A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A.D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D.C. Liebler, D. O'Brien, A. Patel, T.M. Penning
Thu, 06/06/2019 - 01:12
Publication date: Available online 5 June 2019 Food and Chemical ToxicologyAuthor(s): Tongtong Shen, Yufan Miao, Chenchen Ding, Wentao Fan, Shuhui Liu, Yanan Lv, Xiaona Gao, Marthe De Boevre, Liping Yan, Sheila Okoth, Sarah De Saeger, Suquan SongAbstractZearalenone (ZEA) can widely contaminate crops and agricultural products. The ingestion of ZEA-contaminated food or feed affects the integrity...
Sat, 06/01/2019 - 01:12
Publication date: Available online 30 May 2019 Food and Chemical ToxicologyAuthor(s): Jochem Louisse, Deborah Rijkers, Geert Stoopen, Wendy Jansen Holleboom, Mona Delagrange, Elise Molthof, Patrick P.J. Mulder, Ron L.A.P. Hoogenboom, Marc Audebert, Ad A.C.M. PeijnenburgAbstractPyrrolizidine alkaloids (PAs) are secondary metabolites from plants that have been found in substantial amounts in herbal...
Sun, 05/26/2019 - 01:13
Publication date: Available online 24 May 2019 Food and Chemical ToxicologyAuthor(s): Nurshad Ali, Gisela H. DegenAbstractThe Fusarium toxin zearalenone (ZEN) is of concern due to its pronounced estrogenic effects in mammalian species. ZEN contaminates various cereal crops and grain-based food along with modified forms which contribute to overall mycoestrogen exposure. As no data exist on the...
Sat, 05/25/2019 - 01:12
Publication date: Available online 23 May 2019 Food and Chemical ToxicologyAuthor(s): Cathy Lester, John Troutman, Cindy Obringer, Ken Wehmeyer, Peter Stoffolano, Michael Karb, Yan Xu, Amy Roe, Greg Carr, Karen Blackburn, Catherine MahonyAbstract1,2-Unsaturated pyrrolizidine alkaloids (PAs) are sometimes present in foods or herbal supplements/medicines as impurities and pose potential concerns...
Fri, 05/24/2019 - 01:11
Publication date: Available online 23 May 2019 Food and Chemical ToxicologyAuthor(s): Haroon Khan, Muhammad Zafar, Seema Patel, SM Mukarrum Shah, Anupam BishayeeAbstractα-glucosidase inhibition is a rational approach in the effective management of type 2 diabetes. Several inhibitors of this enzyme class are in clinical use, but are riddled with efficacy, potency and safety challenges. For this...
Mon, 05/20/2019 - 01:10
Publication date: Available online 18 May 2019 Food and Chemical ToxicologyAuthor(s): Lu Chen, Patrick P.J. Mulder, Ad Peijnenburg, Ivonne M.C.M. RietjensAbstractIn this study five types of herbal teas were used to quantify the effect of comminution of the leaves on resulting PA exposure. Results show that PA levels extracted from intact leaves were consistently lower than from comminuted tea...
Fri, 05/17/2019 - 01:14
Publication date: Available online 16 May 2019 Food and Chemical ToxicologyAuthor(s): Véronique Sirot, Gilles Riviere, Stéphane Leconte, Karine Vin, Thiema Traore, Julien Jean, Géraldine Carne, Sébastien Gorecki, Bruno Veyrand, Philippe Marchand, Bruno Le Bizec, Cravedi Jean-Pierre, Cyril Feidt, Paule Vasseur, Marine Lambert, Chanthadary Inthavong, Thierry Guerin, Marion HulinAbstractA total diet...
Mon, 05/13/2019 - 01:11
Publication date: Available online 11 May 2019 Food and Chemical ToxicologyAuthor(s): Lenis Liverpool-Tasie, Nikita Saha Turna, Oluwatoyin Ademola, Adewale Obadina, Felicia WuAbstractAflatoxin and fumonisin are two major foodborne mycotoxins: toxic chemicals produced by fungi that contaminate food commodities including maize, a staple food in sub-Saharan Africa. Aflatoxin causes liver cancer, and...
Tue, 04/30/2019 - 01:14
Publication date: Available online 28 April 2019 Food and Chemical ToxicologyAuthor(s): Arnau Vidal, Salma Ouhibi, Ridha Gali, Abderrazzek Hedhili, Sarah De Saeger, Marthe De BoevreAbstractPatulin (PAT) is a common mycotoxin in fruit products, especially in apples and apple-based products. The European Commission has set maximum levels for PAT in food. Nevertheless, worrying PAT levels were...
Sun, 04/28/2019 - 01:13
Publication date: Available online 25 April 2019 Food and Chemical ToxicologyAuthor(s): Iman Saleh, Ipek GoktepeAbstractMycotoxins are the secondary metabolites secreted by different types of fungi to which humans can get exposed mainly via ingestion. Patulin (C7H6O4) is a polyketide lactone produced by various fungal specifies, including Penicillium expansum as the main producer. P. expansum can...
Sun, 04/28/2019 - 01:13
Publication date: Available online 26 April 2019 Food and Chemical ToxicologyAuthor(s): Belqes Ahmad Al-Jaal, Morana Jaganjac, Andrei Barcaru, Peter Horvatovich, Aishah LatiffAbstractHuman exposure to mycotoxins occurs mostly through dietary intake, although exposure through dermal and inhalation routes has also been shown. Depending on the type of mycotoxins, the applied dose and duration of...
Wed, 04/10/2019 - 01:14
Publication date: Available online 8 April 2019 Food and Chemical ToxicologyAuthor(s): Verónica García Ibarra, Raquel Sendón, Juana Bustos, Perfecto Paseiro Losada, Ana Rodríguez Bernaldo de QuirósAbstractFood packaging may be a potential source of contamination, through the migration of chemicals from the packaging into the food, thus food consumption is an important route of human exposure to...
Tue, 04/09/2019 - 01:12
Publication date: Available online 6 April 2019 Food and Chemical ToxicologyAuthor(s): Chibundu N. Ezekiel, Michael Sulyok, Isaac M. Ogara, Wilfred A. Abia, Benedikt Warth, Bojan Šarkanj, Paul C. Turner, Rudolf KrskaAbstractIn order to understand the changes in toxic metabolite profiles in uncooked and cooked foods, samples of flour/grain (n = 40) and their corresponding plate-ready food (n = 39...
Sat, 03/30/2019 - 01:13
Publication date: Available online 27 March 2019 Food and Chemical ToxicologyAuthor(s): Larissa T. Franco, Tânia Petta, George E. Rottinghaus, Keliani Bordin, Gilmar A. Gomes, Paula Alvito, Ricardo Assunção, Carlos A.F. OliveiraAbstractThis study aimed to assess the exposure of Brazilian residents (N = 86) from rural areas to multiple mycotoxins and characterize the associated risk in two...
Wed, 03/27/2019 - 01:14
Publication date: Available online 25 March 2019 Food and Chemical ToxicologyAuthor(s): Oludemi Taofiq, Francisca Rodrigues, Lillian Barros, Maria F. Barreiro, Isabel C.F.R. Ferreira, M. Beatriz P.P. OliveiraAbstractMushrooms are important sources of natural bioactive compounds that are increasingly used as cosmeceutical ingredients. In this context, ethanolic extracts were prepared from...
Mon, 03/25/2019 - 01:13
Publication date: Available online 23 March 2019 Food and Chemical ToxicologyAuthor(s): Xia Li, Jun-Li Lu, Jian-Xia Sun, Xin-Wei Jiang, Xu-Sheng Li, Ye Li, Rui Jiao, Ling-Min Tian, Wei-Bin BaiAbstractCadmium (Cd) is a poisonous metal that is toxic for male reproduction. Cyanidin-3-O-glucoside (C3G) as typical anthocyanin benefits many organs. In this study, we investigated the protective effects...
Thu, 02/14/2019 - 01:11
Publication date: Available online 11 February 2019 Food and Chemical ToxicologyAuthor(s): Mengxue Peng, Jiawei Liu, Zhihong LiangAbstractThe multiple toxic effects of ochratoxin A (OTA) are a threat for human and animal. This study aimed to examine whether B. subtilis CW14 protected against OTA-induced barrier disruption and cell damage to Caco-2 cells. The results showed that Caco-2 cells...
Mon, 02/11/2019 - 01:16
Publication date: Available online 10 February 2019 Food and Chemical ToxicologyAuthor(s): Samira Eslamizad, Farzad Kobarfard, Christina Tsitsimpikou, Aristides M. Tsatsakis, Kimia Tabib, Hassan YazdanpanahAbstractAcrylamide is a chemical, often present in bread, legally classified as carcinogen, mutagen and reproductive toxicant. Since bread is consumed both world-wide and in Iran, determination...
Sat, 02/09/2019 - 01:07
Publication date: Available online 7 February 2019 Food and Chemical ToxicologyAuthor(s): Christina Mantzouki, Despoina Bliatka, Paschalia K. Iliadou, Alexandra Margeli, Ioannis Papassotiriou, George Mastorakos, Eleni Kousta, Dimitrios G. GoulisAbstractBackgroundBisphenol A (BPA) has been associated with male reproductive dysfunction. However, few studies have assessed BPA according to the cause...
Mon, 02/04/2019 - 01:13
Publication date: Available online 1 February 2019 Food and Chemical ToxicologyAuthor(s): V. García-Herranz, A. Valdehita, J.M. Navvas, M.L. Fernández-CruzAbstractThe toxicity of mycotoxins is well recognized in mammals, but their effects on fish have received less attention. Moreover, in the last years several studies have reported that some mycotoxins may act as endocrine disruptors. The aim of...
Fri, 02/01/2019 - 01:12
Publication date: Available online 30 January 2019 Food and Chemical ToxicologyAuthor(s): Merve Bacanli, Nurşen BaşaranAbstractVeterinary medicines, especially antibiotics, are among the most important components related to animal feed production. Generally, the main use of antibiotics in animals is for the treatment and prevention of diseases and growth promotion. Antibiotic usage in animals may...
Mon, 01/21/2019 - 01:11
Publication date: Available online 19 January 2019 Food and Chemical ToxicologyAuthor(s): Jian Ji, Qiuyun Wang, Hao Wu, Shuang Xia, Hongyan Guo, Ivana Blaženović, Yinzhi Zhang, Xiulan SunAbstractMetabolic profiling in Caco-2 cells was studied for the combined toxic effects of deoxynivalenol (DON), zearalenone (ZEN), and Aflatoxin B1 (AFB1) through untargeted GC-MS. The GC-MS spectra of Caco-2 ...
Sun, 01/20/2019 - 01:12
Publication date: Available online 18 January 2019 Food and Chemical ToxicologyAuthor(s): Pei Pei, Xiaofeng Yao, Liping Jiang, Tianming Qiu, Ningning Wang, Lei Yang, Ni Gao, Zhidong Wang, Guang Yang, Xiaofang Liu, Shuang Liu, Xue Jia, Ye Tao, Sen Wei, Xiance SunAbstractLow-level inorganic arsenic (iAs) in drinking water is a risk factor for β cells dysfunction. Taurine (Tau) is a kind of semi-...
Sat, 01/12/2019 - 01:11
Publication date: Available online 8 January 2019 Food and Chemical ToxicologyAuthor(s): Yuri L. Protsenko, Boris A. Katsnelson, Svetlana V. Klinova, Oleg N. Lookin, Alexander A. Balakin, Larisa V. Nikitina, Oksana P. Gerzen, Salavat R. Nabiev, Ilzira A. Minigalieva, Larisa I. Privalova, Vladimir B. Gurvich, Marina P. Sutunkova, Leonid B. KatsnelsonAbstractA moderate subchronic lead intoxication...
Sat, 01/05/2019 - 01:11
Publication date: Available online 4 January 2019 Food and Chemical ToxicologyAuthor(s): Kijoon Kim, Melissa M. Melough, Terrence M. Vance, Dongwoo Kim, Hwayoung Noh, Sung I. Koo, Ock K. ChunAbstractA preliminary study by our group suggested that the absorption and accumulation of cadmium may be affected by zinc intake. Tobacco smoke is one major source of cadmium exposure that highly influences...
Sat, 12/29/2018 - 01:13
Publication date: Available online 25 December 2018 Food and Chemical ToxicologyAuthor(s): Young-Min Lee, Jong Pil Park, Kye-Taek Lim, Sei-Jung LeeAbstractRhus verniciflua stokes (RVS) has been used as a functional food to cure inflammatory diseases in Korea. In the present study, we carry out an investigation of the cellular mechanism of a 36 kDa glycoprotein isolated from RVS fruit (RVS...
Wed, 12/19/2018 - 01:10
Publication date: Available online 18 December 2018 Food and Chemical ToxicologyAuthor(s): Elisavet A. Renieri, Irina V. Safenkova, Athanasios Κ. Alegakis, Elvira S. Slutskaya, Venetia Kokaraki, Maroudio Kentouri, Boris B. Dzantiev, Aristidis M. TsatsakisAbstractCadmium (Cd), lead (Pb) and mercury (Hg) presence was investigated in the muscle tissue of gilthead seabream and seabass, collected from...
Mon, 12/17/2018 - 01:11
Publication date: Available online 14 December 2018 Food and Chemical ToxicologyAuthor(s): M.L. González Pereyra, M.P. Martínez, L.R. CavaglieriAbstractMicrobial degradation of aflatoxins (AFs) is an alternative to the use of mycotoxin binders. The lactone ring is a possible target for microbial enzymes and its cleavage reduces AFs toxicity. The aim of this study was to isolate and identify...
Sun, 12/09/2018 - 01:11
Publication date: Available online 7 December 2018 Food and Chemical ToxicologyAuthor(s): Bharati Bhattacharjee, Palash Kumar Pal, Arnab Kumar Ghosh, Sanatan Mishra, Aindrila Chattopadhyay, Debasish BandyopadhyayAbstractCadmium (Cd) is one of the most ubiquitous toxic heavy metal in the environment. The present study was conducted to evaluate the protective role of aqueous bark extract of...
Thu, 11/22/2018 - 01:11
Publication date: Available online 20 November 2018 Food and Chemical ToxicologyAuthor(s): Magda Carvajal-Moreno, Manuel Vargas-Ortiz, Estela Hernández-Camarillo, Silvia Ruiz-Velasco, Francisco Rojo-CallejaAbstractAflatoxins (AFs) are toxic secondary metabolites of the fungi Aspergillus flavus, A. parasiticus and A. nomius. The fungi produce these AFs in cereals, oilseeds and spices. AFs have...
Thu, 11/22/2018 - 01:11
Publication date: Available online 20 November 2018 Food and Chemical ToxicologyAuthor(s): R.E. Adams, J.A. Brickel, V.S. BhatAbstractDietary supplements are regulated by the U.S. FDA as a subset of foods. Most botanical dietary ingredients do not have pesticide tolerances, resulting in the enforcement of zero tolerance or general maximum residue limits (GMRL), rather than utilizing science-...

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