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Food and Chemical Toxicology

Fri, 06/14/2019 - 01:12
Publication date: Available online 13 June 2019 Food and Chemical ToxicologyAuthor(s): Giacomo Russo, Francesco Barbato, Damiano Gustavo Mita, Lucia GrumettoAbstractBisphenol A and its analogues belong to the class of endocrine disrupting chemicals, massively employed by industries to produce polycarbonate and epoxy resins, designed to be in direct contact with foodstuffs. Their leaching from the...
Mon, 06/10/2019 - 01:12
Publication date: Available online 8 June 2019 Food and Chemical ToxicologyAuthor(s): A.M. Api, D. Belsito, D. Botelho, M. Bruze, G.A. Burton, J. Buschmann, M.L. Dagli, M. Date, W. Dekant, C. Deodhar, M. Francis, A.D. Fryer, L. Jones, K. Joshi, S. La Cava, A. Lapczynski, D.C. Liebler, D. O'Brien, A. Patel, T.M. Penning
Thu, 06/06/2019 - 01:12
Publication date: Available online 5 June 2019 Food and Chemical ToxicologyAuthor(s): Tongtong Shen, Yufan Miao, Chenchen Ding, Wentao Fan, Shuhui Liu, Yanan Lv, Xiaona Gao, Marthe De Boevre, Liping Yan, Sheila Okoth, Sarah De Saeger, Suquan SongAbstractZearalenone (ZEA) can widely contaminate crops and agricultural products. The ingestion of ZEA-contaminated food or feed affects the integrity...
Sat, 06/01/2019 - 01:12
Publication date: Available online 30 May 2019 Food and Chemical ToxicologyAuthor(s): Jochem Louisse, Deborah Rijkers, Geert Stoopen, Wendy Jansen Holleboom, Mona Delagrange, Elise Molthof, Patrick P.J. Mulder, Ron L.A.P. Hoogenboom, Marc Audebert, Ad A.C.M. PeijnenburgAbstractPyrrolizidine alkaloids (PAs) are secondary metabolites from plants that have been found in substantial amounts in herbal...
Sun, 05/26/2019 - 01:13
Publication date: Available online 24 May 2019 Food and Chemical ToxicologyAuthor(s): Nurshad Ali, Gisela H. DegenAbstractThe Fusarium toxin zearalenone (ZEN) is of concern due to its pronounced estrogenic effects in mammalian species. ZEN contaminates various cereal crops and grain-based food along with modified forms which contribute to overall mycoestrogen exposure. As no data exist on the...
Sat, 05/25/2019 - 01:12
Publication date: Available online 23 May 2019 Food and Chemical ToxicologyAuthor(s): Cathy Lester, John Troutman, Cindy Obringer, Ken Wehmeyer, Peter Stoffolano, Michael Karb, Yan Xu, Amy Roe, Greg Carr, Karen Blackburn, Catherine MahonyAbstract1,2-Unsaturated pyrrolizidine alkaloids (PAs) are sometimes present in foods or herbal supplements/medicines as impurities and pose potential concerns...
Fri, 05/24/2019 - 01:11
Publication date: Available online 23 May 2019 Food and Chemical ToxicologyAuthor(s): Haroon Khan, Muhammad Zafar, Seema Patel, SM Mukarrum Shah, Anupam BishayeeAbstractα-glucosidase inhibition is a rational approach in the effective management of type 2 diabetes. Several inhibitors of this enzyme class are in clinical use, but are riddled with efficacy, potency and safety challenges. For this...
Mon, 05/20/2019 - 01:10
Publication date: Available online 18 May 2019 Food and Chemical ToxicologyAuthor(s): Lu Chen, Patrick P.J. Mulder, Ad Peijnenburg, Ivonne M.C.M. RietjensAbstractIn this study five types of herbal teas were used to quantify the effect of comminution of the leaves on resulting PA exposure. Results show that PA levels extracted from intact leaves were consistently lower than from comminuted tea...
Fri, 05/17/2019 - 01:14
Publication date: Available online 16 May 2019 Food and Chemical ToxicologyAuthor(s): Véronique Sirot, Gilles Riviere, Stéphane Leconte, Karine Vin, Thiema Traore, Julien Jean, Géraldine Carne, Sébastien Gorecki, Bruno Veyrand, Philippe Marchand, Bruno Le Bizec, Cravedi Jean-Pierre, Cyril Feidt, Paule Vasseur, Marine Lambert, Chanthadary Inthavong, Thierry Guerin, Marion HulinAbstractA total diet...
Mon, 05/13/2019 - 01:11
Publication date: Available online 11 May 2019 Food and Chemical ToxicologyAuthor(s): Lenis Liverpool-Tasie, Nikita Saha Turna, Oluwatoyin Ademola, Adewale Obadina, Felicia WuAbstractAflatoxin and fumonisin are two major foodborne mycotoxins: toxic chemicals produced by fungi that contaminate food commodities including maize, a staple food in sub-Saharan Africa. Aflatoxin causes liver cancer, and...
Tue, 04/30/2019 - 01:14
Publication date: Available online 28 April 2019 Food and Chemical ToxicologyAuthor(s): Arnau Vidal, Salma Ouhibi, Ridha Gali, Abderrazzek Hedhili, Sarah De Saeger, Marthe De BoevreAbstractPatulin (PAT) is a common mycotoxin in fruit products, especially in apples and apple-based products. The European Commission has set maximum levels for PAT in food. Nevertheless, worrying PAT levels were...
Sun, 04/28/2019 - 01:13
Publication date: Available online 25 April 2019 Food and Chemical ToxicologyAuthor(s): Iman Saleh, Ipek GoktepeAbstractMycotoxins are the secondary metabolites secreted by different types of fungi to which humans can get exposed mainly via ingestion. Patulin (C7H6O4) is a polyketide lactone produced by various fungal specifies, including Penicillium expansum as the main producer. P. expansum can...
Sun, 04/28/2019 - 01:13
Publication date: Available online 26 April 2019 Food and Chemical ToxicologyAuthor(s): Belqes Ahmad Al-Jaal, Morana Jaganjac, Andrei Barcaru, Peter Horvatovich, Aishah LatiffAbstractHuman exposure to mycotoxins occurs mostly through dietary intake, although exposure through dermal and inhalation routes has also been shown. Depending on the type of mycotoxins, the applied dose and duration of...
Wed, 04/10/2019 - 01:14
Publication date: Available online 8 April 2019 Food and Chemical ToxicologyAuthor(s): Verónica García Ibarra, Raquel Sendón, Juana Bustos, Perfecto Paseiro Losada, Ana Rodríguez Bernaldo de QuirósAbstractFood packaging may be a potential source of contamination, through the migration of chemicals from the packaging into the food, thus food consumption is an important route of human exposure to...
Tue, 04/09/2019 - 01:12
Publication date: Available online 6 April 2019 Food and Chemical ToxicologyAuthor(s): Chibundu N. Ezekiel, Michael Sulyok, Isaac M. Ogara, Wilfred A. Abia, Benedikt Warth, Bojan Šarkanj, Paul C. Turner, Rudolf KrskaAbstractIn order to understand the changes in toxic metabolite profiles in uncooked and cooked foods, samples of flour/grain (n = 40) and their corresponding plate-ready food (n = 39...
Sat, 03/30/2019 - 01:13
Publication date: Available online 27 March 2019 Food and Chemical ToxicologyAuthor(s): Larissa T. Franco, Tânia Petta, George E. Rottinghaus, Keliani Bordin, Gilmar A. Gomes, Paula Alvito, Ricardo Assunção, Carlos A.F. OliveiraAbstractThis study aimed to assess the exposure of Brazilian residents (N = 86) from rural areas to multiple mycotoxins and characterize the associated risk in two...
Wed, 03/27/2019 - 01:14
Publication date: Available online 25 March 2019 Food and Chemical ToxicologyAuthor(s): Oludemi Taofiq, Francisca Rodrigues, Lillian Barros, Maria F. Barreiro, Isabel C.F.R. Ferreira, M. Beatriz P.P. OliveiraAbstractMushrooms are important sources of natural bioactive compounds that are increasingly used as cosmeceutical ingredients. In this context, ethanolic extracts were prepared from...
Mon, 03/25/2019 - 01:13
Publication date: Available online 23 March 2019 Food and Chemical ToxicologyAuthor(s): Xia Li, Jun-Li Lu, Jian-Xia Sun, Xin-Wei Jiang, Xu-Sheng Li, Ye Li, Rui Jiao, Ling-Min Tian, Wei-Bin BaiAbstractCadmium (Cd) is a poisonous metal that is toxic for male reproduction. Cyanidin-3-O-glucoside (C3G) as typical anthocyanin benefits many organs. In this study, we investigated the protective effects...
Thu, 02/14/2019 - 01:11
Publication date: Available online 11 February 2019 Food and Chemical ToxicologyAuthor(s): Mengxue Peng, Jiawei Liu, Zhihong LiangAbstractThe multiple toxic effects of ochratoxin A (OTA) are a threat for human and animal. This study aimed to examine whether B. subtilis CW14 protected against OTA-induced barrier disruption and cell damage to Caco-2 cells. The results showed that Caco-2 cells...
Mon, 02/11/2019 - 01:16
Publication date: Available online 10 February 2019 Food and Chemical ToxicologyAuthor(s): Samira Eslamizad, Farzad Kobarfard, Christina Tsitsimpikou, Aristides M. Tsatsakis, Kimia Tabib, Hassan YazdanpanahAbstractAcrylamide is a chemical, often present in bread, legally classified as carcinogen, mutagen and reproductive toxicant. Since bread is consumed both world-wide and in Iran, determination...
Sat, 02/09/2019 - 01:07
Publication date: Available online 7 February 2019 Food and Chemical ToxicologyAuthor(s): Christina Mantzouki, Despoina Bliatka, Paschalia K. Iliadou, Alexandra Margeli, Ioannis Papassotiriou, George Mastorakos, Eleni Kousta, Dimitrios G. GoulisAbstractBackgroundBisphenol A (BPA) has been associated with male reproductive dysfunction. However, few studies have assessed BPA according to the cause...
Mon, 02/04/2019 - 01:13
Publication date: Available online 1 February 2019 Food and Chemical ToxicologyAuthor(s): V. García-Herranz, A. Valdehita, J.M. Navvas, M.L. Fernández-CruzAbstractThe toxicity of mycotoxins is well recognized in mammals, but their effects on fish have received less attention. Moreover, in the last years several studies have reported that some mycotoxins may act as endocrine disruptors. The aim of...
Fri, 02/01/2019 - 01:12
Publication date: Available online 30 January 2019 Food and Chemical ToxicologyAuthor(s): Merve Bacanli, Nurşen BaşaranAbstractVeterinary medicines, especially antibiotics, are among the most important components related to animal feed production. Generally, the main use of antibiotics in animals is for the treatment and prevention of diseases and growth promotion. Antibiotic usage in animals may...
Mon, 01/21/2019 - 01:11
Publication date: Available online 19 January 2019 Food and Chemical ToxicologyAuthor(s): Jian Ji, Qiuyun Wang, Hao Wu, Shuang Xia, Hongyan Guo, Ivana Blaženović, Yinzhi Zhang, Xiulan SunAbstractMetabolic profiling in Caco-2 cells was studied for the combined toxic effects of deoxynivalenol (DON), zearalenone (ZEN), and Aflatoxin B1 (AFB1) through untargeted GC-MS. The GC-MS spectra of Caco-2 ...
Sun, 01/20/2019 - 01:12
Publication date: Available online 18 January 2019 Food and Chemical ToxicologyAuthor(s): Pei Pei, Xiaofeng Yao, Liping Jiang, Tianming Qiu, Ningning Wang, Lei Yang, Ni Gao, Zhidong Wang, Guang Yang, Xiaofang Liu, Shuang Liu, Xue Jia, Ye Tao, Sen Wei, Xiance SunAbstractLow-level inorganic arsenic (iAs) in drinking water is a risk factor for β cells dysfunction. Taurine (Tau) is a kind of semi-...
Sat, 01/12/2019 - 01:11
Publication date: Available online 8 January 2019 Food and Chemical ToxicologyAuthor(s): Yuri L. Protsenko, Boris A. Katsnelson, Svetlana V. Klinova, Oleg N. Lookin, Alexander A. Balakin, Larisa V. Nikitina, Oksana P. Gerzen, Salavat R. Nabiev, Ilzira A. Minigalieva, Larisa I. Privalova, Vladimir B. Gurvich, Marina P. Sutunkova, Leonid B. KatsnelsonAbstractA moderate subchronic lead intoxication...
Sat, 01/05/2019 - 01:11
Publication date: Available online 4 January 2019 Food and Chemical ToxicologyAuthor(s): Kijoon Kim, Melissa M. Melough, Terrence M. Vance, Dongwoo Kim, Hwayoung Noh, Sung I. Koo, Ock K. ChunAbstractA preliminary study by our group suggested that the absorption and accumulation of cadmium may be affected by zinc intake. Tobacco smoke is one major source of cadmium exposure that highly influences...
Sat, 12/29/2018 - 01:13
Publication date: Available online 25 December 2018 Food and Chemical ToxicologyAuthor(s): Young-Min Lee, Jong Pil Park, Kye-Taek Lim, Sei-Jung LeeAbstractRhus verniciflua stokes (RVS) has been used as a functional food to cure inflammatory diseases in Korea. In the present study, we carry out an investigation of the cellular mechanism of a 36 kDa glycoprotein isolated from RVS fruit (RVS...
Wed, 12/19/2018 - 01:10
Publication date: Available online 18 December 2018 Food and Chemical ToxicologyAuthor(s): Elisavet A. Renieri, Irina V. Safenkova, Athanasios Κ. Alegakis, Elvira S. Slutskaya, Venetia Kokaraki, Maroudio Kentouri, Boris B. Dzantiev, Aristidis M. TsatsakisAbstractCadmium (Cd), lead (Pb) and mercury (Hg) presence was investigated in the muscle tissue of gilthead seabream and seabass, collected from...
Mon, 12/17/2018 - 01:11
Publication date: Available online 14 December 2018 Food and Chemical ToxicologyAuthor(s): M.L. González Pereyra, M.P. Martínez, L.R. CavaglieriAbstractMicrobial degradation of aflatoxins (AFs) is an alternative to the use of mycotoxin binders. The lactone ring is a possible target for microbial enzymes and its cleavage reduces AFs toxicity. The aim of this study was to isolate and identify...
Sun, 12/09/2018 - 01:11
Publication date: Available online 7 December 2018 Food and Chemical ToxicologyAuthor(s): Bharati Bhattacharjee, Palash Kumar Pal, Arnab Kumar Ghosh, Sanatan Mishra, Aindrila Chattopadhyay, Debasish BandyopadhyayAbstractCadmium (Cd) is one of the most ubiquitous toxic heavy metal in the environment. The present study was conducted to evaluate the protective role of aqueous bark extract of...
Thu, 11/22/2018 - 01:11
Publication date: Available online 20 November 2018 Food and Chemical ToxicologyAuthor(s): Magda Carvajal-Moreno, Manuel Vargas-Ortiz, Estela Hernández-Camarillo, Silvia Ruiz-Velasco, Francisco Rojo-CallejaAbstractAflatoxins (AFs) are toxic secondary metabolites of the fungi Aspergillus flavus, A. parasiticus and A. nomius. The fungi produce these AFs in cereals, oilseeds and spices. AFs have...
Thu, 11/22/2018 - 01:11
Publication date: Available online 20 November 2018 Food and Chemical ToxicologyAuthor(s): R.E. Adams, J.A. Brickel, V.S. BhatAbstractDietary supplements are regulated by the U.S. FDA as a subset of foods. Most botanical dietary ingredients do not have pesticide tolerances, resulting in the enforcement of zero tolerance or general maximum residue limits (GMRL), rather than utilizing science-...
Thu, 11/22/2018 - 01:11
Publication date: Available online 20 November 2018 Food and Chemical ToxicologyAuthor(s): Blake R. Rushing, Mustafa I. SelimAbstractAflatoxins are a class of carcinogenic mycotoxins produced by Aspergillus fungi and are known to contaminate a large portion of the world's food supply. Aflatoxin B1 (AFB1) is the most potent of these compounds and has been well-characterized to lead to the...
Wed, 11/21/2018 - 01:10
Publication date: Available online 19 November 2018 Food and Chemical ToxicologyAuthor(s): Carl Andre, Roland Buesen, Brandy Riffle, Christine Wandelt, Jordan B. Sottosanto, Heike Marxfeld, Volker Strauss, Bennard van Ravenzwaay, Elizabeth A. LipscombAbstractThe omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs) eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) are recognized for...
Tue, 11/13/2018 - 01:11
Publication date: Available online 11 November 2018 Food and Chemical ToxicologyAuthor(s): Liang Gong, Hong Zhu, Taotao Li, Guangfeng Ming, Xuewu Duan, Jiasheng Wang, Yueming JiangAbstractOchratoxin A (OTA) and citrinin (CTN) are important mycotoxins, which often coexist in food and feed stuff. In this study, individual and combinative cytotoxicity of OTA and CTN were tested in human embryonic...
Thu, 10/11/2018 - 01:11
Publication date: Available online 9 October 2018 Food and Chemical ToxicologyAuthor(s): Fu-Mei Huang, Yu-Chao Chang, Shiuan-Shinn Lee, Yung-Chyuan Ho, Ming-Ling Yang, Hui-Wen Lin, Yu-Hsiang KuanAbstractBisphenol A (BPA) is primarily used in production of polycarbonate plastics and epoxy resins including plastic containers. BPA is an endocrine disruptor and supposes to induce asthma and cancer....
Mon, 10/08/2018 - 01:12
Publication date: Available online 6 October 2018 Food and Chemical ToxicologyAuthor(s): Walkiria Levy, Karl-Werner Schramm, Florian Mertes, Bernhard Henkelmann, Martina Maywald, Peter Uciechowski, Alexander Loa, Johannes Haedrich, Ines Thiem, Henner Hollert, Roland Goerlich, Thorsten Bernsmann, Lothar RinkAbstractRecent European regulations have indicated the need for new bioanalytical screening...
Mon, 10/08/2018 - 01:12
Publication date: Available online 6 October 2018 Food and Chemical ToxicologyAuthor(s): Chan-Min Liu, Hui-Xin Yang, Jie-Qiong Ma, Wei Yang, Zhao-Jun Feng, Jian-Mei Sun, Chao Cheng, Jun Li, Hong JiangAbstractPaeonol is a natural flavonoid isolated from Moutan Cortex, which has been found to exhibit antioxidant, anti-apoptotic, anti-aging and anti-inflammatory bioactivities. Herein, we...
Mon, 10/08/2018 - 01:12
Publication date: Available online 6 October 2018 Food and Chemical ToxicologyAuthor(s): Phani M. Gummadidala, Mayomi H. Omebeyinje, James A. Burch, Paramita Chakraborty, Prasanta K. Biswas, Koyeli Banerjee, Qian Wang, Rubaiya Jesmin, Chandrani Mitra, Peter D.R. Moeller, Geoffrey I. Scott, Anindya ChandaAbstractA mini-survey of 29 different foods produced by 21 different Indian manufacturers was...
Sat, 10/06/2018 - 01:12
Publication date: Available online 1 October 2018 Food and Chemical ToxicologyAuthor(s): Gang Qian, Dandan Liu, Lili Hou, Mohammed Hamid, Xingxiang Chen, Fang Gan, Kehe HuangAbstractOchratoxin A (OTA) could cause a variety of toxicological effects especially nephrotoxicity in animals and humans. Autophagy is a highly conserved metabolic process that plays an important role in the maintenance of...
Sat, 10/06/2018 - 01:12
Publication date: Available online 4 October 2018 Food and Chemical ToxicologyAuthor(s): Zhendong Yang, Kathy S. Xue, Xiulan Sun, Phillip L. Williams, Jia-Sheng Wang, Lili TangAbstractIn this study, the possible molecular mechanisms of zearalenone (ZEA)-induced reproductive and developmental toxic effects in Caenorhabditis elegans (C. elegans) were investigated. Differential gene expression...
Fri, 10/05/2018 - 01:12
Publication date: Available online 3 October 2018 Food and Chemical ToxicologyAuthor(s): Hyun Jung Lee, Min Cheol Pyo, Hye Soo Shin, Dojin Ryu, Kwang-Won LeeAbstractBecause ochratoxin A (OTA) is widely found in foods, people are susceptible to OTA exposure. The mechanism leading to renal toxicity induced by OTA remains unclear. The aim of this study was to investigate OTA-induced toxicity in...
Fri, 10/05/2018 - 01:12
Publication date: Available online 3 October 2018 Food and Chemical ToxicologyAuthor(s): Matthew Dietrich
Tue, 10/02/2018 - 01:12
Publication date: November 2018 Food and Chemical Toxicology, Volume 121Author(s): D. Carballo, J.C. Moltó, H. Berrada, E. FerrerAbstractA study on a set of ready-to-eat meals (n = 328) based on cereals, legumes, vegetables, fish and meat was carried out to determine the natural presence of twenty-seven mycotoxins by both liquid chromatography and gas chromatography coupled mass spectrometry in...
Sun, 09/30/2018 - 01:12
Publication date: Available online 29 September 2018 Food and Chemical ToxicologyAuthor(s): Sébastien Cambier, Masatake Fujimura, Jean-Paul BourdineaudAbstractMethylmercury (MeHg) taken up through fish consumption can be transferred from the mother to the fetus during pregnancy. In the present study, pregnant rat mothers were contaminated with environmentally relevant doses of 36 and 76 ng MeHg/g...
Thu, 09/27/2018 - 01:11
Publication date: Available online 25 September 2018 Food and Chemical ToxicologyAuthor(s): Sophie Fraeyman, Evelyne Meyer, Mathias Devreese, Gunther Antonissen, Kristel Demeyere, Freddy Haesebrouck, Siska CroubelsAbstractThe emerging Fusarium mycotoxins beauvericin (BEA) and enniatin (ENN) A, ENN A1, ENN B and ENN B1 gain increasing interest due to their highly prevalent contamination of cereals...
Mon, 09/24/2018 - 01:12
Publication date: Available online 22 September 2018 Food and Chemical ToxicologyAuthor(s): Julie P. Meneely, Jana Hajšlová, Rudolf Krska, Christopher T. ElliottAbstractAs human co-exposure to natural toxins through food and water is inevitable, risk assessments to safeguard health are necessary. Aflatoxin B1 and fumonisin B1, frequent co-contaminants of maize and microcystin-LR, produced in...
Mon, 09/24/2018 - 01:12
Publication date: Available online 22 September 2018 Food and Chemical ToxicologyAuthor(s): A. Bertero, L.J. Spicer, F. CaloniAbstractFusarium mycotoxins, such as fumonisins, trichothecenes, zearalenone and emerging fusariotoxins, common contaminants of feed and food, have received increased interest, due to the possible impact on animal and human health.In this context, it is urgent to focus our...
Sun, 09/23/2018 - 01:12
Publication date: November 2018 Food and Chemical Toxicology, Volume 121Author(s): C. SiekeAbstractCumulative dietary risks for the German population owing to pesticide residues in foods were assessed using food monitoring and consumption data. Based on grouping principles for cumulative assessment groups (CAG) as defined by the European Food Safety Authority, probabilistic modelling gave...

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