You are here

Fungal Genetics and Biology

Sun, 08/19/2018 - 01:07
Available online 18 August 2018 Author(s): Brandon T. Pfannenstiel, Claudio Greco, Andrew T. Sukowaty, Nancy P. KellerAbstractDue to the role, both beneficial and harmful, that fungal secondary metabolites play in society, the study of their regulation is of great importance. Genes for any one secondary metabolite are contiguously arranged in a biosynthetic gene cluster (BGC) and subject to...
Thu, 04/12/2018 - 16:46
Publication date: Available online 12 April 2018 Author(s): Opemipo Esther Fasoyin, Bin Wang, Mengguang Qiu, Xiaoyun Han, Kuang-Ren Chung, Shihua Wang Carbon catabolite repression (CCR) is a very important mechanism employed in the utilization of carbon as an energy source, required for the regulation of growth, development and secondary metabolite production in fungi. Despite...
Thu, 03/01/2018 - 11:37
Publication date: Available online 1 March 2018 Author(s): Ioannis F. Kalampokis, George C. Kapetanakis, Konstantinos A. Aliferis, George Diallinas The development of fungicide-resistant fungal populations represents a major challenge for the agrochemical and agri-food sectors, which threatens food supply and security. The issue becomes complex for fungi that cause quantitative and...
Wed, 01/03/2018 - 08:07
Publication date: Available online 3 January 2018 Author(s): Huifang Wang, Zhangjiang He, Linli Luo, Xin Zhao, Zhuoyue Lu, Tingying Luo, Min Li, Yongjun Zhang The aldo-keto reductases (AKRs) belong to the NADP-dependent oxidoreductase superfamily, which play important roles in various physiological functions in prokaryotic and eukaryotic organisms. However, many AKR...
Sun, 08/20/2017 - 11:36
Publication date: Available online 19 August 2017 Author(s): Isaura Caceres, Rhoda El Khoury, Sylviane Bailly, Isabelle P. Oswald, Olivier Puel, Jean-Denis Bailly Aspergillus flavus, a soil-borne pathogen, represents a danger for humans and animals since it produces the carcinogenic mycotoxin Aflatoxin B1 (AFB1). Approaches aiming the reduction of this fungal contaminant mainly...
Fri, 07/07/2017 - 04:43
Publication date: Available online 6 July 2017 Author(s): I. Kutay Ozturk, Pranav Chettri, Pierre-Yves Dupont, Irene Barnes, Rebecca L. McDougal, Geromy G. Moore, Andre Sim, Rosie E. Bradshaw Fungal secondary metabolites have many important biological roles and some, like the toxic polyketide aflatoxin, have been intensively studied at the genetic level. Complete sets of...
Sat, 04/22/2017 - 10:23
Publication date: Available online 22 April 2017 Author(s): Perng-Kuang Chang, Leslie L. Scharfenstein, Robert W. Li, Natalia Arroyo-Manzanares, Sarah De Saeger, José Diana Di Mavungu Aspergillus flavus aswA (AFLA_085170) is a gene encoding a Zn(II)2Cys6 DNA-binding domain and a transcriptional activation domain, DUF3468. Disruption of aswA yielded strains that made a truncated...
Wed, 02/15/2017 - 08:07
Publication date: Available online 14 February 2017 Author(s): Kunlong Yang, Yinghang Liu, Linlin Liang, Zhenguo Li, Qiuping Qin, Xinyi Nie, Shihua Wang Cyclic AMP signaling controls a range of physiological processes in response to extracellular stimuli in organisms. Among the signaling cascades, cAMP, as a second messenger, is orchestrated by adenylate cyclase(biosynthesis)...
Sun, 11/20/2016 - 09:35
Publication date: Available online 19 November 2016 Author(s): Bruno Giuliano Garisto Donzelli, B. Gillian Turgeon, Donna M. Gibson, Stuart B. Krasnoff Based on genomic analysis, polyketide synthase (PKS) and nonribosomal peptide synthetase (NRPS) pathways account for biosynthesis of the majority of the secondary metabolites produced by the entomopathogenic fungus Metarhizium...
Fri, 11/04/2016 - 04:40
Publication date: Available online 3 November 2016 Author(s): Pranav Chettri, Rosie E. Bradshaw In filamentous fungi both pathway-specific and global regulators regulate genes involved in the biosynthesis of secondary metabolites. LaeA is a global regulator that was named for its mutant phenotype, loss of aflR expression, due to its effect on the aflatoxin-pathway regulator AflR in...
Sat, 01/23/2016 - 08:06
Publication date: Available online 22 January 2016 Author(s): Yong Fuga Li, Kathleen J.S. Tsai, Colin J.B. Harvey, James Jian Li, Beatrice E. Ary, Erin E. Berlew, Brenna L. Boehman, David M. Findley, Alexandra G. Friant, Christopher A. Gardner, Michael P. Gould, Jae H. Ha, Brenna K. Lilley, Emily L. McKinstry, Saadia Nawal, Robert C. Parry, Kristina W....
Thu, 09/10/2015 - 07:20
Publication date: Available online 9 September 2015 Author(s): Farhana Runa, Ignazio Carbone, Deepak Bhatnagar, Gary A. Payne Aspergillus flavus is a major producer of aflatoxin and an opportunistic pathogen for a wide range of hosts. Understanding genotypic and phenotypic variation within strains of A. flavus is important for controlling disease and reducing aflatoxin contamination...
Sun, 07/19/2015 - 06:20
Publication date: September 2015 , Volume 82 Author(s): Mónica Lamas-Maceiras, Esther Rodríguez-Belmonte, Manuel Becerra, M Isabel González-Siso, M Esperanza Cerdán It has been previously reported that Gcr1 differentially controls growth and sugar utilization in Saccharomyces cerevisiae and Kluyveromyces lactis , although the regulatory mechanisms causing activation of glycolytic...
Fri, 06/05/2015 - 03:20
Publication date: Available online 4 June 2015 Author(s): Jeffrey W. Cary , Valdet Uka , Zheng Han , Dieter Buyst , Pamela Y. Harris-Coward , Kenneth C. Ehrlich , Qijian Wei , Deepak Bhatnagar , Patrick F. Dowd , Stacey L. Martens , Ana M. Calvo , José C. Martins , Lynn Vanhaecke , Tom Coenye , Sarah De Saeger , José Diana Di Mavungu The genome of the filamentous fungus,...