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Natural toxins

Fri, 04/19/2019 - 01:12
Publication date: Available online 17 April 2019Source: Author(s): Lucian Del Fabbro, Cristiano Ricardo Jesse, Marcelo Gomes de Gomes, Carlos Borges Filho, Franciele Donato, Leandro Cattelan Souza, André Rossito Goes, Ana Flásvia Furian, Silvana Peterini BoeiraAbstractThe mycotoxin zearalenone (ZEA) has strong estrogenic effects and elicits reproductive toxicity. Chrysin is a natural flavonoid...
Thu, 04/18/2019 - 00:00
Toxins, Vol. 11, Pages 229: Dehydrocrenatidine Inhibits Voltage-Gated Sodium Channels and Ameliorates Mechanic Allodia in a Rat Model of Neuropathic Pain Toxins doi: 10.3390/toxins11040229 Authors: Fang Zhao Qinglian Tang Jian Xu Shuangyan Wang Shaoheng Li Xiaohan Zou Zhengyu Cao Picrasma quassioides (D. Don) Benn, a medical plant, is used in clinic to treat inflammation, pain...
Tue, 04/16/2019 - 00:00
Toxins, Vol. 11, Pages 227: Mycotoxins during the Processes of Nixtamalization and Tortilla Production Toxins doi: 10.3390/toxins11040227 Authors: Sara Schaarschmidt Carsten Fauhl-Hassek Tortillas are a traditional staple food in Mesoamerican cuisine, which have also become popular on a global level, e.g., for wraps or as snacks (tortilla chips). Traditional tortilla production includes...
Mon, 04/15/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 5, Page 796-803, May 2019.
Mon, 04/15/2019 - 00:00
Toxins, Vol. 11, Pages 224: Occurrence of Mycotoxigenic Fusarium Species and Competitive Fungi on Preharvest Maize Ear Rot in Poland Toxins doi: 10.3390/toxins11040224 Authors: Karolina Gromadzka Lidia Błaszczyk Jerzy Chełkowski Agnieszka Waśkiewicz Maize has become one of the most important crops for food and feed production—both as a silage and crop residue worldwide...
Sun, 04/14/2019 - 01:12
Available online 12 April 2019 Author(s): Lijun Luo, Shuai Ma, Libo Li, Xiaohong Liu, Jiayi Zhang, Xia Li, Dong Liu, Tianyan YouAbstractAccurate and early diagnosis of mycotoxin is particularly significant to the food and agricultural product safety. In the present work, a sensitive and effective monitoring method for zearalenone (ZEN) was exploited based on a novel self-enhanced...
Sat, 04/13/2019 - 00:00
Toxins, Vol. 11, Pages 221: An Attempt to Characterize the Ciguatoxin Profile in Seriola fasciata Causing Ciguatera Fish Poisoning in Macaronesia Toxins doi: 10.3390/toxins11040221 Authors: Pablo Estevez David Castro Ana Pequeño-Valtierra José M. Leao Oscar Vilariño Jorge Diogène Ana Gago-Martínez Ciguatera Fish Poisoning is a worldwide concern caused by the consumption of...
Fri, 04/12/2019 - 00:00
Toxins, Vol. 11, Pages 219: Mycotoxin Decontamination Efficacy of Atmospheric Pressure Air Plasma Toxins doi: 10.3390/toxins11040219 Authors: Nataša Hojnik Martina Modic Gabrijela Tavčar-Kalcher Janja Babič James L. Walsh Uroš Cvelbar Mycotoxins, the toxic secondary metabolites of mould species, are a growing global concern, rendering almost 25% of all food produced unfit for...
Fri, 04/12/2019 - 00:00
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.8b05948
Wed, 04/10/2019 - 01:12
Available online 8 April 2019 Author(s): Xi Wu, Xinxin Zhang, Yanqiang Yang, Yurong Liu, Xiaoni ChenAbstractA novel and sensitive deep eutectic solvent-based matrix solid phase dispersion (DES-MSPD) method for the determination of aflatoxins (AFB1, AFB2, AFG1, AFG2) in various crops was established using high-performance liquid chromatography with fluorescence detection (HPLC-FLD). The DES-MSPD...
Wed, 04/10/2019 - 00:00
Toxins, Vol. 11, Pages 217: Assessment of Toxic Effects of Ochratoxin A in Human Embryonic Stem Cells Toxins doi: 10.3390/toxins11040217 Authors: Slaven Erceg Eva María Mateo Iván Zipancic Francisco Javier Rodríguez Jiménez María Amparo Pérez Aragó Misericordia Jiménez José Miguel Soria Mª Ángeles Garcia-Esparza Ochratoxin A (OTA) is a mycotoxin produced by different...
Wed, 04/10/2019 - 00:00
Toxins, Vol. 11, Pages 215: Fumonisin Production by Fusarium verticillioides in Maize Genotypes Cultivated in Different Environments Toxins doi: 10.3390/toxins11040215 Authors: Oelton Ferreira Rosa Junior Mateus Sunti Dalcin Vitor L. Nascimento Fernando Machado Haesbaert Talita Pereira de Souza Ferreira Rodrigo Ribeiro Fidelis Renato de Almeida Sarmento Raimundo Wagner de Souza...
Tue, 04/09/2019 - 01:12
Publication date: July 2019 , Volume 153Author(s): Vipin Kumar Singh, Somenath Das, Abhishek Kumar Dwivedy, Raju Rathore, Nawal Kishore DubeyAbstractThe study reports industrial significance of chemically characterized nanoencapuslated Ocimum sanctum essential oil (OSEO) against fungi contaminating herbal raw materials and aflatoxin B1 secretion. The chitosan encapsulated OSEO exhibited enhanced...
Tue, 04/09/2019 - 01:12
Publication date: Available online 6 April 2019 Food and Chemical ToxicologyAuthor(s): Chibundu N. Ezekiel, Michael Sulyok, Isaac M. Ogara, Wilfred A. Abia, Benedikt Warth, Bojan Šarkanj, Paul C. Turner, Rudolf KrskaAbstractIn order to understand the changes in toxic metabolite profiles in uncooked and cooked foods, samples of flour/grain (n = 40) and their corresponding plate-ready food (n = 39...
Tue, 04/09/2019 - 00:00
Toxins, Vol. 11, Pages 214: Fluorescence Spectroscopic Investigation of Competitive Interactions between Quercetin and Aflatoxin B1 for Binding to Human Serum Albumin Toxins doi: 10.3390/toxins11040214 Authors: Tan Chen Ma Liu Zhou Zhang Guo Liu Dai Yu Aflatoxin B1 (AFB1) is a highly toxic mycotoxin found worldwide in cereals, food, and animal feeds. AFB1 binds...
Mon, 04/08/2019 - 01:08
Available online 2 April 2019 Author(s): Monika Coton, Arnaud Auffret, Elisabeth Poirier, Stella Debaets, Emmanuel Coton, Philippe DantignyAbstractMoldy food products that are not subject to pathogenic bacterial contamination could be trimmed by consumers to remove fungal mycelium before consumption. However, prior to giving such recommendations to consumers, it is necessary to evaluate potential...
Mon, 04/08/2019 - 00:00
Toxins, Vol. 11, Pages 211: 15N Stable Isotope Labeling PSTs in Alexandrium minutum for Application of PSTs as Biomarker Toxins doi: 10.3390/toxins11040211 Authors: Xie Li Song Zhang Hu Liang Yang The dinoflagellate Alexandrium minutum (A. minutum) which can produce paralyticshellfish toxins (PSTs) is often used as a model to study the migration, biotransformation,...
Sat, 04/06/2019 - 01:12
Publication date: 30 August 2019 , Volume 290Author(s): Sandra Leonardo, Sotiris Kiparissis, Maria Rambla-Alegre, Sergi Almarza, Ana Roque, Karl B. Andree, Aris Christidis, Cintia Flores, Josep Caixach, Katrina Campbell, Christopher T. Elliott, Katerina Aligizaki, Jorge Diogène, Mònica CampàsAbstractTwo small Lagocephalus sceleratus juveniles were captured in picarel targeting catches from North...
Fri, 04/05/2019 - 01:14
Publication date: June 2019Source: , Volume 164Author(s): Yongfeng Zhou, Yongcheng Jin, Hao Yu, Anshan Shan, Jinglin Shen, Changhai Zhou, Yun Zhao, Hengtong Fang, Xin Wang, Junmei Wang, Yurong Fu, Rui Wang, Ruihua Li, Jing ZhangAbstractAflatoxins are widely occurring food contaminants that are particularly harmful to dairy products and cows. The plant polyphenol resveratrol has been reported to...
Fri, 04/05/2019 - 00:00
Abstract Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin produced by Fusarium fungi. ZEN has endocrine disruptor effects and could impair the hormonal balance. Here, we aimed at investigating possible effects of ZEN on metabolism-related pathways and its relation to epigenetic mechanisms in breast adenocarcinoma (MCF7) and breast epithelial (MCF10F) cells. Using the...
Fri, 04/05/2019 - 00:00
Toxins, Vol. 11, Pages 205: Exposure Assessment and Risk Characterization of Aflatoxin M1 Intake through Consumption of Milk and Yoghurt by Student Population in Serbia and Greece Toxins doi: 10.3390/toxins11040205 Authors: Bozidar Udovicki Ilija Djekic Eleni P. Kalogianni Andreja Rajkovic The objective of this research was to perform an exposure assessment of aflatoxin M1 (AFM1)...
Thu, 04/04/2019 - 00:00
Abstract This study attempts to evaluate the potential aflatoxin binder activity of a molecularly imprinted polymer (TMU95) synthesized to target the aflatoxin B1 (AFB1) analog molecule in comparison to a commercial toxin binder (CTB). Adsorption experiments were carried out to assess the ability to bind to AFB1 at various pH values. The strength of binding was investigated by...
Wed, 04/03/2019 - 00:00
Journal of Agricultural and Food ChemistryDOI: 10.1021/acs.jafc.8b06810
Tue, 04/02/2019 - 00:00
Toxins, Vol. 11, Pages 198: The Pressure of Fusarium Disease and Its Relation with Mycotoxins in The Wheat Grain and Malt Toxins doi: 10.3390/toxins11040198 Authors: Valentina Spanic Zvonimir Zdunic Georg Drezner Bojan Sarkanj Fusarium head blight (FHB) is one of the most destructive wheat fungal diseases, causing yield loss, quality reduction, and accumulation of mycotoxins. The...
Sun, 03/31/2019 - 00:00
Toxins, Vol. 11, Pages 196: Detection of Five Mycotoxins in Different Food Matrices in the Malaysian Market by Using Validated Liquid Chromatography Electrospray Ionization Triple Quadrupole Mass Spectrometry Toxins doi: 10.3390/toxins11040196 Authors: Ali Mohamed Ali Alsharif Yeun-Mun Choo Guan-Huat Tan Mycotoxins are common food contaminants which cause poisoning and severe health...
Sat, 03/30/2019 - 01:13
Publication date: Available online 27 March 2019 Food and Chemical ToxicologyAuthor(s): Larissa T. Franco, Tânia Petta, George E. Rottinghaus, Keliani Bordin, Gilmar A. Gomes, Paula Alvito, Ricardo Assunção, Carlos A.F. OliveiraAbstractThis study aimed to assess the exposure of Brazilian residents (N = 86) from rural areas to multiple mycotoxins and characterize the associated risk in two...
Sat, 03/30/2019 - 00:00
Toxins, Vol. 11, Pages 192: Candida utilis ATCC 9950 Cell Walls and β(1,3)/(1,6)-Glucan Preparations Produced Using Agro-Waste as a Mycotoxins Trap Toxins doi: 10.3390/toxins11040192 Authors: Anna Bzducha-Wróbel Marcin Bryła Iwona Gientka Stanisław Błażejak Monika Janowicz Mycotoxins are harmful contaminants of food and feed worldwide. Feed additives with the abilities to trap...
Fri, 03/29/2019 - 00:00
Toxins, Vol. 11, Pages 189: Dinophysis Species and Diarrhetic Shellfish Toxins: 20 Years of Monitoring Program in Andalusia, South of Spain Toxins doi: 10.3390/toxins11040189 Authors: Fernández Mamán Jaén Fernández Fuentes Ocaña Gordillo In Andalusia, the official monitoring program for toxic phytoplankton and marine biotoxins was launched in 1994 to comply with European...
Fri, 03/29/2019 - 00:00
Toxins, Vol. 11, Pages 188: Paralytic Shellfish Toxins in Surf Clams Mesodesma donacium during a Large Bloom of Alexandrium catenella Dinoflagellates Associated to an Intense Shellfish Mass Mortality Toxins doi: 10.3390/toxins11040188 Authors: Gonzalo Álvarez Patricio A. Díaz Marcos Godoy Michael Araya Iranzu Ganuza Roberto Pino Francisco Álvarez José Rengel Cristina Hernández...
Thu, 03/28/2019 - 00:00
Toxins, Vol. 11, Pages 187: Biomarkers for Exposure as A Tool for Efficacy Testing of A Mycotoxin Detoxifier in Broiler Chickens and Pigs Toxins doi: 10.3390/toxins11040187 Authors: Lauwers Croubels Letor Gougoulias Devreese Applying post-harvest control measures such as adding mycotoxin detoxifying agents is a frequently-used mitigation strategy for mycotoxins. EFSA states...
Wed, 03/27/2019 - 01:14
Publication date: Available online 25 March 2019Source: LWTAuthor(s): Amrita Yadav, Anupam Kujur, Akshay Kumar, Prem Pratap Singh, Bhanu Prakash, N.K. DubeyAbstractThe present study investigates the efficacy of the nanoencapsulated mace essential oil (Ne-MEO) against the toxigenic strain of A. flavus (CP-05), aflatoxin B1 production, free radical generation and speculated in-vitro mechanism of...
Tue, 03/26/2019 - 00:00
Abstract A study was conducted to investigate the frequency and levels of AFM1 and AFM2 in urine from children who attended the emergency service of a pediatric referral hospital in Bogota, Colombia. A survey on the consumption of foods likely to be a source of aflatoxins and on sociodemographic variables was conducted as well. The frequency of AFM1 in urine was found to be 41.7...
Mon, 03/25/2019 - 14:24
ABSTRACT BACKGROUND Wheat grains are susceptible to infection by various toxigenic fungal species that produce toxic metabolites called mycotoxins. This makes wheat one of the most important daily dietary sources of mycotoxins for consumers. As germination is popularly used to improve the nutritional quality of grains, the present study was carried out to understand its effect on the toxin...
Mon, 03/25/2019 - 00:00
Toxins, Vol. 11, Pages 180: Reduction of Mycotoxins during Fermentation of Whole Grain Sorghum to Whole Grain Ting (a Southern African Food) Toxins doi: 10.3390/toxins11030180 Authors: Oluwafemi Ayodeji Adebo Eugenie Kayitesi Patrick Berka Njobeh Mycotoxins are fungal secondary metabolites that pose health risks to exposed individuals, requiring necessary measures to reduce them....
Sat, 03/23/2019 - 00:00
Toxins, Vol. 11, Pages 176: Harmful Effects and Control Strategies of Aflatoxin B1 Produced by Aspergillus flavus and Aspergillus parasiticus Strains on Poultry: Review Toxins doi: 10.3390/toxins11030176 Authors: Ahmed Mohamed Fouad Dong Ruan HebatAllah Kasem El-Senousey Wei Chen Shouqun Jiang Chuntian Zheng The presence of aflatoxin B1 (AFB1) in poultry diets decreases the...
Fri, 03/22/2019 - 05:49
Scope Pyrrolizidine alkaloids (PA) are common phytotoxins. Intoxication can lead to liver damage. Previous studies showed PA‐induced apoptosis in liver cells. However, the exact role of the extrinsic apoptotic pathway has not been investigated yet. Our study aimed to analyze whether the PA representative lasiocarpine sensitizes human liver cells towards extrinsic Fas‐mediated apoptosis. Methods...
Thu, 03/21/2019 - 00:00
Abstract This work characterizes the adsorption of aflatoxin B1 (AFB1), ochratoxin A (OTA), and zearalenone (ZEN) by dry micronized olive pomace (OliPom) and grape stems (GrapStem). Their performance was compared with that of three other materials, activated carbon (ActCarb), bentonite (Bent), and a commercial product (ComProd). Experiments were conducted in vitro at several pH...
Wed, 03/20/2019 - 01:12
Available online 18 March 2019 Author(s): Qifang Wu, Huirong XuAbstractTo explore the effect of signal acquisition way on screening ability, the multiplexing fiber optic laser induced fluorescence spectroscopy (LIFS) system with one-, two- and three-probe, were employed respectively to detect artificially aflatoxin B1 (AFB1, 5, 10, 20, 30, and 50 ppb) contaminated 300 pistachio kernels in this...
Tue, 03/19/2019 - 00:00
Toxins, Vol. 11, Pages 171: Multi LC-MS/MS and LC-HRMS Methods for Determination of 24 Mycotoxins including Major Phase I and II Biomarker Metabolites in Biological Matrices from Pigs and Broiler Chickens Toxins doi: 10.3390/toxins11030171 Authors: Marianne Lauwers Siegrid De Baere Ben Letor Michael Rychlik Siska Croubels Mathias Devreese A reliable and practical multi-method...
Sat, 03/16/2019 - 01:12
Available online 15 March 2019 Author(s): Lisa M. Frisch, Ludwig NiessenAbstractThe mycotoxin patulin is a toxic fungal secondary metabolite occurring in food worldwide. Methods for rapid, simple and specific detection of patulin-producing fungi in food and feed are therefore urgently needed. In the current study, a loop-mediated isothermal amplification (LAMP) assay based on the isoepoxydon...
Sat, 03/16/2019 - 00:00
Toxins, Vol. 11, Pages 165: Variation of Fungal Metabolites in Sorghum Malts Used to Prepare Namibian Traditional Fermented Beverages Omalodu and Otombo Toxins doi: 10.3390/toxins11030165 Authors: Sylvia N. Nafuka Jane M. Misihairabgwi Ronnie Bock Anthony Ishola Michael Sulyok Rudolf Krska Sorghum malts, which are important ingredients in traditional fermented beverages, are...
Fri, 03/15/2019 - 00:00
Toxins, Vol. 11, Pages 163: Study on Trichothecene and Zearalenone Presence in Romanian Wheat Relative to Weather Conditions Toxins doi: 10.3390/toxins11030163 Authors: Oana Stanciu Cristina Juan Houda Berrada Doina Miere Felicia Loghin Jordi Mañes To evaluate the influence of weather conditions on mycotoxin presence in wheat, deoxynivalenol (DON), 3-acetyldeoxynivalenol (3AcDON...
Thu, 03/14/2019 - 00:00
Herein, we reported a novel direct competitive fluorescence-linked immunosorbent assay (dcFLISA) for the ultrasensitive detection of aflatoxin M1 (AFM1) in pasteurized milk, yogurt, and milk powder using 150-nm quantum dot beads (QB) as the carrier of competing antigen. Large QB were applied to decrease the binding affinity of the competing antigen to antibody and enhance the fluorescent signal...
Wed, 03/13/2019 - 11:47
Summary The patulin biosynthesis is one of model pathways in an understanding of secondary metabolite biology and network novelties in fungi. However, molecular regulation mechanism of patulin biosynthesis and contribution of each gene related to the different catalytic enzymes in the biochemical steps of the pathway remain largely unknown in fungi. In this study, the genetic components of...
Wed, 03/13/2019 - 11:47
Summary The patulin biosynthesis is one of model pathways in an understanding of secondary metabolite biology and network novelties in fungi. However, molecular regulation mechanism of patulin biosynthesis and contribution of each gene related to the different catalytic enzymes in the biochemical steps of the pathway remain largely unknown in fungi. In this study, the genetic components of...

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