Aflatoxins

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Wed, 06/03/2020 - 03:41
Background Aflatoxins, a kind of carcinogen, have attracted increasing attentions due to their toxicity and harmfulness to human health. Traditional methods for aflatoxins analysis usually involve tedious extraction steps with subsequent derivatization process. Herein, a simple and efficient liquid phase micro‐extraction (LPME) method based on deep eutectic solvents (DESs) for direct analysis of...
Tue, 06/02/2020 - 03:50
Author(s): Ahmed Salem Sebaei, Hoda M. Refai, Hannah Tarek Elbadry, Sandra Mounir Armeya Aflatoxins are very dangerous natural toxins that are mainly produced by fungal organisms that are attracted to oil seeds, nuts and spices, where they are causing health and economic problems. Therefore, in this study, with 117 samples of tahini (a product made from toasted sesame seeds) were collected from...
Mon, 06/01/2020 - 03:49
Author(s): Esther GARCIA-CELA, Carol VERHEECKE-VAESSEN, Maria GUTIERREZ-POZO, Elisavet KIAITSI, Alessandra MARCON-GASPERINI, Naresh MAGAN, Angel MEDINA The aim was to decipher the temporal impact of key interacting climate change (CC) abiotic factors of temperature (30 vs 37 °C), water activity (aw; 0.985 vs 0.930) and CO2 exposure (400 vs 1000 ppm) on (a) growth of Aspergillus flavus and effects...
Mon, 06/01/2020 - 03:47
Author(s): Bolong Fang, Shaolan Xu, Youju Huang, Fengmei Su, Zhen Huang, Hao Fang, Juan Peng, Yonghua Xiong, Weihua Lai In this study, we developed an indirect competitive plasmonic immunoassay using glucose oxidase (GOx)-induced redox reaction to etch Au nanorods (AuNRs) for qualitative and quantitative detection of aflatoxin M1 (AFM1) in milk. In this system, streptavidin (SA) was selected as a...
Sat, 05/30/2020 - 03:51
Author(s): Shirin Hooshfar, Roya Khosrokhavar, Hassan Yazdanpanah, Samira Eslamizad, Farzad Kobarfard, Firuzeh Nazari, Venetia Kokaraki, Manolis Kokkinakis, Marina Goumenou, Christina Tsitsimpikou, Aristides Tsatsakis In this study, two accurate, precise, selective and sensitive methods were developed for determining aflatoxin M1 (AFM1) in infant formula milk using immunoaffinity column clean-up...
Sat, 05/30/2020 - 03:40
Dried beef meat, a locally processed meat from the cow, is vulnerable to contamination by mycotoxins, due to its exposure to the environmental microbiota during processing, drying, and point of sale. In this study, 108 dried beef samples were examined for the occurrence of 17 mycotoxins. Samples were extracted for mycotoxins using solid-liquid phase extraction method, while liquid chromatography...
Thu, 05/28/2020 - 03:51
LWT
Author(s): Anupam Kujur, Akshay Kumar, Amrita Yadav, Bhanu Prakash The study reports the antifungal and aflatoxin B1 (AFB1) inhibitory mode of action of nanoencapsulated Pelargonium graveolens L. essential oil (Ne-PGEO). Nanoencapsulation of PGEO was prepared using chitosan nanoparticles and interactions were confirmed by scanning electron microscopy (SEM), fourier transform infrared spectroscopy...
Thu, 05/28/2020 - 03:48
Royal jelly (RJ) and propolis were able to inhibit the growth of Aspergillus parasiticus with minimum inhibitory concentrations (MICs) of 3,200 and 100 μg/ml, respectively. Combination of RJ and propolis resulted in synergistic interaction with MICs of 200 and 25 μg/ml, respectively, and a fractional inhibitory concentration index of 0.312. RJ and propolis were able to down‐regulate the...
Wed, 05/27/2020 - 03:46
Author(s): Yang Yu, Jianyang Shi, Bingying Xie, Yutong He, Yongping Qin, Dan Wang, Haichun Shi, Yongpei Ke, Qun Sun Chlorine dioxide (ClO2) gas was utilized for detoxifying aflatoxin B1 (AFB1) in corn for the first time. Four degradation compounds were identified by LC–MS as C17H13O8, C17H15O10, C16H15O10, and C15H11O8. Structurally, the biological activity of ClO2-treated AFB1 was removed due to...
Sun, 05/24/2020 - 03:46
Author(s): Bolei Yang, Chenxi Zhang, Xiujuan Zhang, Gang Wang, Li Li, Hairong Geng, Yang Liu Peanut, as a nutritious, healthy and delicious food, is susceptible to contamination by aflatoxin B1 (AFB1) and heavy metals, which has an adverse impact on the healthy development of peanut industry in China. This research was to evaluate the contamination of AFB1 and heavy metals (cadmium, chromium,...
Sun, 05/24/2020 - 03:36
A new method for the quantification of four aflatoxins (AFB1, AFB2, AFG1, and AFG2) in baby food samples is described herein. In this method, the extraction/cleanup step was performed by using multi-walled carbon nanotubes as a sorbent material in a dispersive solid phase procedure. In sequence, these mycotoxins were quantified via liquid chromatographic coupled with tandem mass spectrometry. The...
Sat, 05/23/2020 - 03:55
Author(s): Junmin Ji, Yulan Liu, Dongmin Wang Peanut oil is a traditional high-end food oil, and most consumers enjoy fragrant peanut oil because of its unique flavor. In this paper, crude peanut oils were obtained from skinned and de-skinned peanut kernels by solvent extraction, cold pressing or hot pressing, and then, the contents of aflatoxins (AFs), phthalate esters (PAEs), and polycyclic...
Fri, 05/22/2020 - 03:46
Author(s): Meseret Amde, Ayalew Temsgen, Nigussie Dechassa Aflatoxins (AFs) in food and agricultural products pose serious health hazards to consumers. As a result, exports are restricted and farmers lose much needed income. One major challenge faced in controlling AFs in developing countries in particular is lack of simple and cost-effective methods of analysis. To address this problem, a solid-...
Thu, 05/21/2020 - 03:44
In recent years, there has been an increasing interest in investigating the carcinogenicity of mycotoxins in humans. This systematic review aims to provide an overview of data linking exposure to different mycotoxins with human cancer risk. Publications (2019 and earlier) of case–control or longitudinal cohort studies were identified in PubMed and EMBASE. These articles were then screened by...
Thu, 05/21/2020 - 03:38
Food and crop contaminations with mycotoxins are a severe health risk for consumers and cause high economic losses worldwide. Currently, different chromatographic- and immuno-based methods are used to detect mycotoxins within different sample matrices. There is a need for novel, highly sensitive detection technologies that avoid time-consuming procedures and expensive laboratory equipment but...
Wed, 05/20/2020 - 03:44
Author(s): Syed Wajih ul Hassan, Yumna Sadef, Shabbir Hussain, Muhammad Rafique Asi, Muhammad Yasin Ashraf, Sumera Anwar, Arif Malik The contamination of food with mycotoxins could be a major health risk. Identification and quantification of mycotoxins in maize are essentially required to guarantee food safety. Seven commonly grown maize cultivars were sown at semi-arid conditions in Pakistan....
Wed, 05/20/2020 - 03:40
High level exposure to aflatoxin B1 (AFB1) is known to cause acute liver damage and fatality in animals and humans. The intakes actually causing this acute toxicity have so far been estimated based on AFB1 levels in contaminated foods or biomarkers in serum. The aim of the present study was to predict the doses causing acute liver toxicity of AFB1 in rat and human by an in vitro‐in silico testing...
Tue, 05/19/2020 - 03:45
The aim of this study was to develop a highly-sensitive liquid chromatographic – tandem mass spectrometric (LC-MS/MS) method to investigate the presence of aflatoxins (AFB1, AFB2, AFG1 and AFG2) and ochratoxin A (OTA) in traditional homemade sausages (n = 88) collected from small family farms situated in different regions in Croatia. Aflatoxins were not detected (
Mon, 05/18/2020 - 03:36
Different batches of biomass/feed quality maize contaminated by aflatoxins were processed at the industrial scale (a continuous process and separate discontinuous steps) to evaluate the effect of different cleaning solutions on toxin reduction. The investigated cleaning solutions included: (i) mechanical size separation of coarse, small and broken kernels, (ii) removal of dust/fine particles...
Sun, 05/17/2020 - 03:45
Author(s): Li Min, Dagang Li, Xiong Tong, Hao Sun, Weidong Chen, Gang Wang, Nan Zheng, Jiaqi Wang The incidence of aflatoxin M1 (AFM1) contamination in milk and milk products is a serious health hazard for human worldwide. Thus, the global monitoring of AFM1 in raw milk has been ongoing for decades. In this review, the occurrences of AFM1 in raw milk are summarized worldwide in 32 countries date...
Sun, 05/17/2020 - 03:44
Author(s): Wei Chen, Fen Cai, Qian Wu, Yuhan Wu, Bangben Yao, Jianguo Xu Mycotoxin contaminations of tea have been considered serious problems. The presence of interfering substances presents enormous challenges to accurate detection of hazardous analytes in tea soups. In this work, we have carefully predicted, evaluated, and confirmed the matrix effects in tea that have an undesired influence on...
Sun, 05/17/2020 - 03:36
The most popular and economically important traditional dairy products in Egypt are raw milk, Karish cheese (an Arabian dairy product made from defatted cow milk) and Zabady (an Arabian yoghurt made from buffalo and cow milk). In this study, 302 traditional dairy samples including raw milk (120), white Karish cheese (118), and Zabady (64) were analyzed for aflatoxin M1 (AFM1) during different...
Fri, 05/15/2020 - 03:35
Probiotic strain Eurotium cristatum was isolated from Chinese Fuzhuan brick-tea and tested for its in vitro activity against aflatoxigenic Aspergillus flavus. Results indicated that E. cristatum can inhibit the radial growth of A. flavus. Furthermore, this inhibition might be caused by E. cristatum secondary metabolites. The ability of culture filtrate of strain E. cristatum against growth and...
Thu, 05/14/2020 - 03:43
LWT
Author(s): Lin Ye, Yaling Wang, Lijun Sun, Zhijia Fang, Qi Deng, Yuying Huang, Peishan Zheng, Qi Shi, Jianmeng Liao, Jian Zhao The objective of this study was to determine the effects of a high salt culture medium (fish sauce and salted fish) on the detoxification capacity of Lactobacillus acidophilus (L.a), L. bulgaricus (L.b), and L. casei (L.c). These lactic acid bacteria (LAB) strains were...
Sun, 05/10/2020 - 03:35
Medicinal plants are often consumed as infusions with boiled water. Scarce information is available in the literature about the migration of mycotoxins into the resulting beverage and/or the effects of the infusion procedure on the final mycotoxin contents. The aim of the present study was to investigate the impact of the infusion process on mycotoxin contents during medicinal plant preparation....
Sat, 05/09/2020 - 03:44
Author(s): Mosaad A. Abdel-Wahhab, Aziza A. El-Nekeety, Amal S. Hathout, Asmaa S. Salman, Sekena H. Abdel-Aziem, Nabila S. Hassan, Mohamed S. Abdel-Aziz This study aimed to determine the bioactive compounds of Bacillus sp. MERNA97 extract and to evaluate their efficacy against the oxidative damage, genotoxicity, chromosomal aberration and DNA fragmentation in rats treated with AFB1. Sixty male...
Thu, 05/07/2020 - 03:36
Aflatoxin is the most harmful mycotoxin that is ubiquitous in foods and agro-products. Because of its high toxicity, maximum admissible levels of aflatoxins (AF) is regulated worldwide, and monitoring of their occurrence in several commodities is mandatory for assuring food safety and consumers’ health. Considering that the strip method is very simple and convenient for users, in order to enhance...
Thu, 05/07/2020 - 03:36
Aflatoxin B1 (AFB1), which has potent toxicity and carcinogenicity, is a common contaminant of important agricultural commodities. This study aimed to investigate the frequency of corn flour intake and assess the exposure to AFB1 via direct detection of AFB1 in the diet and serum AFB1 exposure biomarker, so as to evaluate their associations with the risk of esophageal precancerous lesions (EPL)....
Tue, 05/05/2020 - 03:46
Author(s): Hamid Khaneghahi Abyaneh, Alireza Bahonar, Negin Noori, Hassan Yazdanpanah, Mohamad Hosein Shojaee Aliabadi We are writing about the recently published letter to the editor in Food Chemistry entitled “Refers to The overall and variations of Aflatoxin M1 contamination of milk in Iran: A systematic review and meta-analysis study, Food Chemistry (2020), doi: https:// doi.org/10.1016/j....
Tue, 05/05/2020 - 03:46
Author(s): María Pía Mom, Stella Maris Romero, Ada Gabriela Larumbe, Leopoldo Iannone, Ricardo Comerio, Camila Soledad Santana Smersu, Mariano Simón, Graciela Vaamonde Aspergillus section Flavi isolates were present in all the samples. • Aflatoxins contamination was detected in most of the samples. • Levels of aflatoxins detected in the samples were very low. Abstract...
Mon, 05/04/2020 - 03:34
Aflatoxin B1 (AFB1) leads to a major risk to poultry and its residues in meat products can also pose serious threat to human health. In this study, after feeding 165-day-old Roman laying hens for 35 days, the toxic effects of aflatoxin B1 at different concentrations were evaluated. The purpose of this study was to explore the mechanism of liver toxicosis responses to AFB1. We found that highly...
Sat, 05/02/2020 - 03:42
LWT
Author(s): Seyed Mohammad Bagher Hashemi, Mohammad Javad Amiri Due to worldwide problems of mycotoxins such as Aflatoxin B1 (AFB1) and aflatoxin G1 (AFG1) in feeds, there is a lot of attention for low costs, practical and high efficiency detoxification methods. The goal of the present study was to examine the capability of two bacteria including L. delbrueckii subsp. lactis and L. fermentum for...
Wed, 04/29/2020 - 03:43
Author(s): Liye Zhu, Chuchu Huang, Xuan Yang, Boyang Zhang, Xiaoyun He, Wentao Xu, Kunlun Huang Aflatoxin B1 (AFB1) is a known carcinogen found in contaminated food and designated by the World Health Organization as a class I carcinogenic substance. AFB1 presents with carcinogenicity, teratogenicity, and mutagenicity, and the liver is the human organ most susceptible to AFB1. Zinc (Zn), which is...
Wed, 04/29/2020 - 03:43
Author(s): Mosaad A. Abdel-Wahhab, Aziza A. El-Nekeety, Amal S. Hathout, Asmaa S. Salman, Sekena H. Abdel-Aziem, Bassem A. Sabry, Nabila S. Hassan, Mohamed S. Abdel-Aziz, Soher E. Aly, Irwandi Jaswir This study aimed to identify the bioactive compounds of the ethyl acetate extract of Aspergillus niger SH2-EGY using GC-MS and to evaluate their protective role against aflatoxin B1 (AFB1)-induced...
Wed, 04/29/2020 - 03:35
Employing theoretical calculations with density functional theory (DFT) using the B3LYP/6-311++G(d,p) functional and basis set, the interaction of the aflatoxin B1 (AFB1) molecule and the functional groups present in the Pyracantha koidzumii biosorbent was investigated. Dissociation free energy and acidity equilibrium constant values were obtained theoretically both in solution (water) and gas...
Tue, 04/28/2020 - 03:35
Maize (Zea mays L.) is one of the major crops susceptible to Aspergillus flavus infection and subsequent contamination with aflatoxins, the most potent naturally produced carcinogenic secondary metabolites. This pathogen can pose serious health concerns and cause severe economic losses due to the Food and Drug Administration (FDA) regulations on permissible levels of aflatoxins in food and feed....
Fri, 04/24/2020 - 03:34
Fungal secondary metabolites play important roles not only in fungal ecology but also in humans living as beneficial medicine or harmful toxins. In filamentous fungi, bZIP-type transcription factors (TFs) are associated with the proteins involved in oxidative stress response and secondary metabolism. In this study, a connection between a bZIP TF and oxidative stress induction of secondary...
Thu, 04/23/2020 - 03:41
Author(s): Huirong He, Da-Wen Sun, Hongbin Pu, Lunjie Huang Aflatoxin B1 (AFB1) as the most toxic mycotoxin in contaminated food can greatly threaten human health, and sensitive and selective detection of AFB1 is thus highly desired. An ultrasensitive surface-enhanced Raman spectroscopy (SERS) aptasensor was developed for AFB1 detection in peanut oil samples. SH-cDNA modified Fe3O4@Au nanoflowers...
Thu, 04/23/2020 - 03:41
Author(s): Shi-Jun Chen, Lian Gan, Ying-Chi Guo, Yong-Jian Liu, Li-Xia Tian This study aimed to investigate if myo-inositol (MI) supplementation could alleviate adverse effects caused by aflatoxin B1 (AFB1) with respect to growth performance, AFB1 residues, immune response and antioxidant status of Litopenaeus vannamei. 800 shrimp (initial weight: 1.1g) were divided into five groups: MI0 (basal...
Thu, 04/23/2020 - 03:32
Aflatoxin B1 (AFB1) is a secondary metabolite produced by some Aspergillus spp. fungi affecting many crops and feed materials. Aflatoxin M1 (AFM1), the 4-hydroxylated metabolite of AFB1, is the main AFB1-related compound present in milk, and it is categorized by the International Agency for Research on Cancer (IARC) as a &ldquo;group 1 human carcinogen&rdquo;. The aim of this work was to...
Wed, 04/22/2020 - 03:42
Author(s): Yongpeng Guo, Xiaojuan Qin, Yu Tang, Qiugang Ma, Jianyun Zhang, Lihong Zhao In the present study, the CotA protein from Bacillus licheniformis ANSB821 was cloned and expressed in Escherichia coli. Apart from the laccase activities, we found that the recombinant CotA could effectively oxidize aflatoxin B1 in the absence of redox mediators. The Km, Kcat and Vmax values of the recombinant...
Tue, 04/21/2020 - 03:35
The diffusion of the legalization of cannabis for recreational, medicinal and nutraceutical uses requires the development of adequate analytical methods to assure the safety and security of such products. In particular, aflatoxins are considered to pose a major risk for the health of cannabis consumers. Among analytical methods that allows for adequate monitoring of food safety, immunoassays play...
Fri, 04/17/2020 - 03:32
Author(s): Amin O. Elzupir, Babiker Y. Abdulkhair This study investigated the health risks associated with aflatoxins (AFs) in processed meat products (PMP) sold in Riyadh, Kingdom of Saudi Arabia. The occurrence and levels of AFs were assessed using high-performance liquid chromatography with fluorescence detection (HPLC-FD), whereas the cancer risk attributed to the consumption of meat products...
Wed, 04/15/2020 - 03:31
Author(s): M.L. González Pereyra, A.L. Di Giacomo, A.L. Lara, M.P. Martínez, L. Cavaglieri Zearalenone, an oestogenic mycotoxin produced by Fusarium sp., occurs naturally in agricultural commodities. Economic losses and health concerns associated to mycotoxins has attracted research interest towards exploring novel approaches to detoxify mycotoxin-contaminated food and feed. The aim of the...
Wed, 04/15/2020 - 03:25
Aspergillus spp. are widely occurring fungi in nature; they produce toxic compounds such as aflatoxins (AFs) and mainly target plant products such as corn and nuts. The development of prevention strategies is challenging because AFs are highly toxic and have been regulated to small concentrations. This study proposes a new strategy of AF prevention through the application of rapid methods using...
Tue, 04/14/2020 - 03:27
A reliable, sensitive and accurate multiple mycotoxin method was developed for the simultaneous determination of 17 mycotoxins in swine, poultry and dairy feeds using stable isotope dilution (13C-ISTD) and (ultra)-high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). A simple QuEChERS-based method (quick, easy, cheap, effective, rugged and safe) was developed consisting of...
Fri, 04/10/2020 - 03:29
Low moisture content ready-to-eat foods vended in Nigerian markets could be pre-packaged or packaged at point of sale. These foods are widely and frequently consumed across Nigeria as quick foods. Despite their importance in the daily diets of Nigerians, a comprehensive study on the diversity of fungi, fungal metabolite production potential, and mycotoxin contamination in the foods has not yet...
Thu, 04/09/2020 - 03:31
Aflatoxins are secondary metabolites produced by specific strains of fungi, especially Aspergillus spp. These natural toxins are mainly found in soil, decaying vegetation and food storage systems and are particularly abundant during drought stress. Aflatoxin contamination is one of the most important threats to food safety and human health due to its toxic, mutagenic and carcinogenic properties....
Wed, 04/08/2020 - 03:33
The emergence of commercial fish farming has stimulated the establishment of fish feed factories in Uganda. However, no information is available on the safety of the feed, mainly due to lack of mycotoxin testing facilities and weak regulatory systems. A study was carried out to examine fungal colonization and mycotoxin contamination in fish feed samples (n = 147) of different types collected from...
Wed, 04/08/2020 - 03:32
Author(s): T.O. Ajiboye , H.O. Raji , H.F. Muritala , O.B. Ojewuyi , M.T. Yakubu The capability of anthocyanins extract of Lannea microcarpa fruits to scavenge reactive oxygen species and stall aflatoxin B1-mediated oxidative rout on cellular proteins, lipids and DNA was investigated. Reactive oxygen species (ROS) scavenging potentials of the anthocyanins extract of Lannea microcarpa fruits (0.2–...

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