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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 26 - 50 of 1978

  1. Aflatoxin B1 Impairs Bone Mineralization in Broiler Chickens

    • Toxins
    • Aflatoxin B1 (AFB1), a ubiquitous mycotoxin in corn-based animal feed, particularly in tropical regions, impairs liver function, induces oxidative stress and disrupts cellular pathways, potentially worsening bone health in modern broilers. A 19-day experiment was conducted to investigate the effects of feeding increasing levels of AFB1-contaminated feed (<2, 75–80, 150, 230–260 and 520–560 ppb) on bone mineralization markers in broilers (n = 360).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Review: Sample Pretreatment and Detection Strategies for Aflatoxins in Foods

    • Food Analytical Methods
    • Aflatoxins (AFs) have strong liver and kidney toxicity, teratogenic, and carcinogenic effects. They can easily contaminate foods such as grains and oilseeds, and can easily enter the human body through the food chain, posing a huge threat to human health. There is an urgent need to establish a rapid, sensitive, and accurate analysis strategy for AFs in food to protect people’s health.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. Determination of aflatoxin M1 and ochratoxin A in breast milk in rural centers of Yazd, Iran: Exposure assessment and risk characterization

    • Mycotoxin Research
    • Breast milk (BM) is considered as the best source of nutrition which could have prevention effects on various diseases in the first years of a child. Along with nutritive compounds, presence of contaminants such as mycotoxins in BM could be transmitted into neonate. The aim of this study was to determine the occurrence, levels, and factors associated with the presence of aflatoxin M1 (AFM1) and ocratoxin a (OTA) in BM samples of nursing mothers in rural centers of Yazd, Iran.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. A Magnetic Reduced Graphene Oxide Nanocomposite: Synthesis, Characterization, and Application for High-Efficiency Detoxification of Aflatoxin B1

    • Toxins
    • (1) Safety problems associated with aflatoxin B1 (AFB1) contamination have always been a major threat to human health. Removing AFB1 through adsorption is considered an attractive remediation technique. (2) Methods: To produce an adsorbent with a high AFB1 adsorption efficiency, a magnetic reduced graphene oxide composite (Fe3O4@rGO) was synthesized using one-step hydrothermal fabrication.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  5. Chicken CYP1A5 is able to hydroxylate aflatoxin B1 in aflatoxin M1

    • Toxicon
    • Aflatoxin B1 (AFB1), a naturally-occurring mycotoxin, can cause severe toxicological and carcinogenic effects in livestock and humans. Given that the chicken is one of the most important food-producing animals, knowledge regarding AFB1 metabolism and enzymes responsible for AFB1 transformation in the chicken has important implications for chicken production and food safety. Previously, we have successfully expressed chicken CYP1A5 and CYP3A37 monooxygenases in E.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Characterization of Aspergillus section Flavi associated with stored grains

    • Mycotoxin Research
    • Increased frequencies of Aspergillus section Flavi and aflatoxins in cereal grains have been seen in recent years due to changes in climate circumstances, such as high temperatures and drought. To assess the microbiological risks of contamination, it is critical to have a reliable and accurate means of identifying the fungi.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  7. Assessing the Risk of Exposure to Aflatoxin B1 through the Consumption of Peanuts among Children Aged 6–59 Months in the Lusaka District, Zambia

    • Toxins
    • Aflatoxins B1 (AFB1) are fungi-produced toxins found in crops like peanuts, maize, and tree nuts. They constitute a public health concern due to their genotoxic and carcinogenic effects. A deterministic exposure risk assessment to AFB1 through the consumption of peanuts was conducted on children using the Margin of Exposure (MOE) and the liver cancer risk approaches.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  8. Aflatoxin M1 Analysis in Urine of Mill Workers in Bangladesh: A Pilot Study

    • Toxins
    • Presence of aflatoxin B1 (AFB1) in food and feed is a serious problem, especially in developing countries. Human exposure to this carcinogenic mycotoxin can occur through dietary intake, but also through inhalation or dermal contact when handling and processing AFB1-contaminated crops. A suitable biomarker of AFB1 exposure by all routes is the occurrence of its hydroxylated metabolite aflatoxin M1 (AFM1) in urine.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. Investigating the Effects of grain quality, processing and environmental conditions on aflatoxin contamination in rice

    • Journal of Food Composition and Analysis
    • This study examined the impact of aflatoxin contamination on rice, a widely consumed staple food. Various forms and types of rice from three regions in Pakistan between 2019 and 2022 were investigated for their relationship with processing, infestation severity and physicochemical characteristics. Semi-polished rice displayed the highest aflatoxin levels employing significant variability, while parboiled rice was also found to be contaminated.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Impact of using cinnamon (Cinnamomum verum) essential oil and its pectin-chitosan nano-emulsion on survival of Aspergillus flavus and total aflatoxin inhibition in beef burger patties

    • Food Control
    • Fungal growth is one of the most common and serious problems faced during food storage. Aspergillus flavus is one of the major storage fungi producing aflatoxins, which are highly toxic and carcinogenic and pose a marked hazard t

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  11. Aflatoxin Decontamination in Maize Steep Liquor Obtained from Bioethanol Production Using Laccases from Species within the Basidiomycota Phylum

    • Toxins
    • Maize (Zea mays L.) is an important crop in Argentina. Aspergillus section Flavi can infect this crop at the pre-harvest stage, and the harvested grains can be contaminated with aflatoxins (AFs). During the production of bioethanol from maize, AF levels can increase up to three times in the final co-products, known as, dry and wet distiller’s grain with solubles (DDGS and WDGS), intended for animal feed.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Mycotoxin contamination in the Arab world: Highlighting the main knowledge gaps and the current legislation

    • Mycotoxin Research
    • Since the discovery of aflatoxins in the 1960s, knowledge in the mycotoxin research field has increased dramatically. Hundreds of review articles have been published summarizing many different aspects, including mycotoxin contamination per country or region. However, mycotoxin contamination in the Arab world, which includes 22 countries in Africa and Asia, has not yet been specifically reviewed.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  13. Aflatoxin M1 removal from milk using activated carbon and bentonite combined with lactic acid bacteria cells

    • International Journal of Dairy Technology
    • Treatment of milk with activated carbon and bentonite combined with lactic acid bacteria cells was an effective approach for removing Aflatoxin M1. This study was planned to explore the AFM1‐reducing potential of various heat and acid‐killed lactic acid bacteria (LAB), activated carbon and bentonite (BENT) in milk contaminated with 0.5 μg/L AFM1 and their impact on milk composition.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  14. Development of isotope dilution-ultrahigh-performance liquid chromatography-tandem mass spectrometry for the accurate determination of aflatoxins in grains

    • Journal of Food Composition and Analysis
    • A method for the accurate determination of aflatoxin B1, B2, G1, and G2 in grains was established using isotope dilution-ultrahigh-performance liquid chromatography-tandem mass spectrometry (ID-UHPLCsingle bondMS/MS). 13C- labeled 

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. Bile Acids Promote Hepatic Biotransformation and Excretion of Aflatoxin B1 in Broiler Chickens

    • Toxins
    • Aflatoxin B1 (AFB1) is a hazardous mycotoxin that often contaminates animal feed and may potentially induce severe liver damage if ingested. The liver is the primary organ responsible for AFB1 detoxification through enzyme-catalyzed xenobiotic metabolism and bile acid (BA)-associated excretion. In this study, we sought to investigate whether exogenous BA improves hepatic AFB1 detoxification to alleviate AFB1-induced liver injury in broiler chickens.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. Prevalence of aflatoxin B1 in four kinds of fermented soybean-related products used as traditional Chinese food

    • LWT
    • This study aimed to investigate the prevalence of aflatoxin B1 (AFB1) in four kinds of fermented soybean-related products used as traditional Chinese food: fermented soybean (FS), fermented qianzhang (FQ), fermented bean curd (FB) and fermented okara (FO). A total of 203 samples, comprising FS (40 samples), FQ (60), FB (41) and FO (62), were collected from free markets of agricultural food, convenience stores and supermarkets in Hubei province, China from November 2021 to January 2022.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  17. Total aflatoxin and ochratoxin A levels, dietary exposure and cancer risk assessment in dried fruits in Türkiye

    • Toxicon
    • This study aimed to measure total aflatoxin (AF) (AFB1, AFB2, AFG1, and AFG2) and ochratoxin A (OTA) levels in dried fruit samples and to evaluate the potential dietary exposure and cancer risk to these 

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Recombinant Oxidase from Armillaria tabescens as a Potential Tool for Aflatoxin B1 Degradation in Contaminated Cereal Grain

    • Toxins
    • Forage grain contamination with aflatoxin B1 (AFB1) is a global problem, so its detoxification with the aim of providing feed safety and cost-efficiency is still a relevant issue. AFB1 degradation by microbial enzymes is considered to be a promising detoxification approach.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  19. Aflatoxins detection in almonds via fluorescence imaging and deep neural network approach

    • Journal of Food Composition and Analysis
    • The detection of aflatoxin B in raw food materials represents a topic of great interest worldwide because of the huge health and economic impact of aflatoxin contamination.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Spherical Fe2O3 nanoparticles inhibit the production of aflatoxins (B1 and B2) and regulate total soluble solids and titratable acidity of peach fruit

    • International Journal of Food Microbiology
    • Aflatoxin is a group I carcinogen and causes significant public health and food safety risks, throughout the world.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Assessment of Aflatoxin M1 in human breast and powdered milk in Tehran, Iran

    • Toxicon
    • Aim and background Aflatoxins, produced by Aspergillus flavus and Aspergillus parasiticus, are among the most toxic mycotoxins. Aflatoxin M1 (AFM1) is a hydroxylated metabolite of aflatoxin B1 (AFB1), found in milk and dairy products from animals fed AFB1-contaminated feed. Consumption of AFM1 has related adverse effects on human health. Breast milk can be a source of contamination for infants due to the presence of AFM.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Radio frequency roasting promotes the degradation of aflatoxin B1 and achieves better quality of peanuts (Arachis hypogaea L.)

    • Food Control
    • Peanuts contaminated with aflatoxin B1 (AFB1) possess serious health risks. Radio frequency (RF) roasting was used for decontamination of AFB1 in peanuts. The effects of RF roasting on AFB1 degradation and peanuts quality were investigated under varied electrode gaps (90, 100, 110, and 120 mm), target temperatures (120, 130, 140, and 150 °C) and initial moisture contents (10%, 15%, 20%, and 25%).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. Mechanism Underlying Bacillus subtilis BS-Z15 Metabolite-Induced Prevention of Grain Contamination by Aspergillus flavus

    • Toxins
    • Aspergillus flavus can cause mildew in corn, peanuts, and other foods as well as animal feed, which seriously endangers human and livestock health; thus, preventing A. flavus contamination is imperative. Previous studies have found that the secondary metabolites of Bacillus subtilis BS-Z15 have broad-spectrum-inhibiting fungal activity, further confirming that the main active inhibiting fungal substance is Mycosubtilin (Myco).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Effects of lycopene on the growth performance, meat quality, and antioxidant capacity of broiler chickens challenged with aflatoxin B1

    • Journal of Food Science
    • Abstract The present study aimed to investigate the effects of dietary lycopene (LYC) supplementation on the growth performance, meat quality, and antioxidant capacity of breast muscle in aflatoxin B1 (AFB1)‐challenged broilers. A total of 192 1‐day‐old healthy Arbor Acres broilers were randomly assigned to 3 treatments, each with 8 replicates (8 broilers per replicate).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Prevalence and Risk Assessment of Aflatoxin in Iowa Corn during a Drought Year

    • International Journal of Food Science
    • Warm temperatures and drought conditions in the United States (US) Corn Belt in 2012 raised concern for widespread aflatoxin (AFL) contamination in Iowa corn. To identify the prevalence of AFL in the 2012 corn crop, the Iowa Department of Agriculture and Land Stewardship (IDALS) conducted a sample of Iowa corn to assess the incidence and severity of AFL contamination.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins