Toxins, Vol. 11, Pages 544: Towards Managing and Controlling Aflatoxin Producers Within Aspergillus Species in Infested Rice Grains Collected from Local Markets in Kenya
Toxins doi: 10.3390/toxins11090544
Rice grains can be attacked by a range of pathogens, including Aspergillus species, which can...
Toxins, Vol. 11, Pages 541: Assessment of Dried Blood Spots for Multi-Mycotoxin Biomarker Analysis in Pigs and Broiler Chickens
Toxins doi: 10.3390/toxins11090541
Siegrid De Baere
Eva Maria Romera Sierra
Dried blood spots (DBSs), a micro-sampling technique whereby a...
Publication date: Available online 14 September 2019Source: Author(s): Ayman A. Hassan, Salma H. Abu Hafsa, Mona M.M.Y. Elghandour, Poonooru Ravi Kanth Reddy, Jose Cedillo Monroy, Abdelfattah Z.M. SalemAbstractEighty-four male New Zealand White rabbits with average body weight 778 ± 65 g were blocked into four groups to evaluate the ability of sodium bentonite and coumarin in alleviating the...
Toxins, Vol. 11, Pages 537: Twenty-Eight Fungal Secondary Metabolites Detected in Pig Feed Samples: Their Occurrence, Relevance and Cytotoxic Effects In Vitro
Toxins doi: 10.3390/toxins11090537
Feed samples are frequently contaminated by a wide range of chemically diverse...
Toxins, Vol. 11, Pages 533: Rationally Designed Synthetic Haptens to Generate Anti-Ciguatoxin Monoclonal Antibodies, and Development of a Practical Sandwich ELISA to Detect Ciguatoxins
Toxins doi: 10.3390/toxins11090533
&ldquo;Ciguatera&rdquo; fish poisoning (CFP) is one of the well-known food poisoning caused by the ingestion...
Toxins, Vol. 11, Pages 532: Aflatoxin B1 Conversion by Black Soldier Fly (Hermetia illucens) Larval Enzyme Extracts
Toxins doi: 10.3390/toxins11090532
H.J. van der Fels-Klerx
Joop J.A. van Loon
The larvae of the black soldier fly (Hermetia illucens L., BSFL) have received increased industrial interest as a novel...
Toxins, Vol. 11, Pages 526: Structures of Reaction Products and Degradation Pathways of Aflatoxin B1 by Ultrasound Treatment
Toxins doi: 10.3390/toxins11090526
Ultrasound is an emerging decontamination technology with potential use in the global food processing industry. In the present study, we explored power ultrasound for...
Publication date: Available online 10 September 2019Source: LWTAuthor(s): Sana Meftah, Salwa Abid, Teresa Dias, Paula RodriguesAbstractProcessed meat products are of worldwide importance, but they are highly prone to fungal and ochratoxin A (OTA) contamination. In previous studies, several Lactic Acid Bacteria (LAB) and yeasts have been tested as biocontrol agents against P. nordicum growth and...
Aflatoxin is a potent carcinogen often found in animal feedstuffs. Although it reportedly impairs development of the preimplantation pig embryo, it is not known whether it adversely affects development of the preimplantation bovine embryo. We conducted 3 experiments to investigate this possibility and determine whether deleterious effects of aflatoxin were caused by increased production of...
Available online 7 September 2019 Author(s): Belén Peromingo, Daniel Caballero, Alicia Rodríguez, Andrés Caro, Mar RodríguezAbstractDry-cured ham may be contaminated with aflatoxin B1 (AFB1) produced by Aspergillus spp. Temperature and water activity (aw) are two key parameters that affect both ham ripening and AFB1 production. The objective of this study was to predict AFB1 production by...
Available online 7 September 2019 Author(s): Nysrine Mannani, Ahmed Tabarani, El Hassane Abdennebi, Abdellah ZinedineAbstractTea is a popular beverage known worldwide with health benefits for consumers. It was considered safe and healthy for centuries. However, recent investigations reported that herbal tea might be contaminated by fungi and mycotoxins. The purpose of this study was to assess,...
The objectives of the present work were to survey, for the first time, the contamination of Portuguese fresh and dry-cured meat products with ochratoxin A (OTA) and aflatoxin B1 (AFB1), and to determine the fungi potentially responsible for this contamination. A total of 128 samples including pork fresh legs, dry-cured legs and shoulders, as well as goat and sheep dry-...
Toxins, Vol. 11, Pages 519: Development of an UPLC-MS/MS Method for the Analysis of Mycotoxins in Rumen Fluid with and without Maize Silage Emphasizes the Importance of Using Matrix-Matched Calibration
Toxins doi: 10.3390/toxins11090519
Siegrid De Baere
Ruminants are less susceptible to the...
Publication date: Available online 4 September 2019Source: Author(s): Agnieszka Rogowska, Paweł Pomastowski, Katarzyna Rafińska, Viorica Railean-Plugaru, Michał Złoch, Justyna Walczak, Bogusław BuszewskiAbstractA study of the mechanism responsible for the zearalenone (ZEA) neutralization by lactic acid bacteria Lactococcus lactis 56 and L929 cell line was carried out by determination of the...
Toxins, Vol. 11, Pages 518: Heterologous Expression and Characterization of A Novel Ochratoxin A Degrading Enzyme, N-acyl-L-amino Acid Amidohydrolase, from Alcaligenes faecalis
Toxins doi: 10.3390/toxins11090518
Ochratoxin A (OTA) is a well-known, natural contaminant in foods and feeds because of its toxic...
Increasing knowledge of the deleterious health and economic impacts of aflatoxin in crop commodities has stimulated global interest in aflatoxin mitigation. Current evidence of the incidence of Aspergillus flavus isolates belonging to vegetative compatibility groups (VCGs) lacking the ability to produce aflatoxins (i.e., atoxigenic) in Ghana may lead to develop an aflatoxin biocontrol strategy to...
Zearalenone (ZEA) is a common mycotoxin produced by fungi within the genus Fusarium. However, few studies have examined the direct effects of the toxin on the mammary glands. In the present study, the effects of ZEA treatment on bovine mammary epithelial cells (MAC-T) from dairy cows were investigated. The cells were treated with different concentrations of ZEA to evaluate the effect of the toxin...
Publication date: Available online 31 August 2019 Food and Chemical ToxicologyAuthor(s): Yancho Zarev, Tania Naessens, Mart Theunis, Esameldin Elgorashi, Sandra Apers, Iliana Ionkova, Luc Verschaeve, Luc Pieters, Nina Hermans, Kenn FoubertAbstractStem bark of Erythrina latissima E. Mey (Leguminosae) contains a wide range of prenylated flavonoids able to counteract the genotoxic properties of...
Available online 29 August 2019 Author(s): Yan Zhao, Yun-Cong Yuan, Xiao-Lin Bai, Yi-Ming Liu, Gui-Fang Wu, Fa-Shu Yang, Xun LiaoAbstractA simple and rapid magnetic solid-phase extraction (MSPE) method using PEGylated multi-walled carbon nanotubes magnetic nanoparticles (PEG-MWCNTs-MNP) as absorbents is proposed for isolation and enrichment of aflatoxin B1 (AFB1), aflatoxin B2 (AFB2), aflatoxin...
This research was done on the assumption that the risk for hepatocellular carcinoma (HCC) development that attributed to the consumption of highly contaminated food (HCF) with aflatoxin, may have a major contribution to the total of expected risk. If this hypothesis is true, it is easy to apply an effective and low‐cost intervention approach by excluding HCF and then subjecting it to...
Contamination by fungi may pose a threat to the long-term operation of the International Space Station because fungi produce organic acids that corrode equipment and mycotoxins that harm human health. Microgravity is an unavoidable and special condition in the space station. However, the influence of microgravity on fungal metabolism has not been well studied. Clinostat rotation is widely used to...
Toxins, Vol. 11, Pages 501: Molecular Characterisation of Aflatoxigenic and Non-Aflatoxigenic Strains of Aspergillus Section Flavi Isolated from Imported Peanuts along the Supply Chain in Malaysia
Toxins doi: 10.3390/toxins11090501
Mahmud Ab Rashid Nor-Khaizura
Cheow Keat Chin
Nik Iskandar Putra Samsudin
Abdul Halim Farawahida...
Toxins, Vol. 11, Pages 495: Influence of Two Garlic-Derived Compounds, Propyl Propane Thiosulfonate (PTS) and Propyl Propane Thiosulfinate (PTSO), on Growth and Mycotoxin Production by Fusarium Species In Vitro and in Stored Cereals
Toxins doi: 10.3390/toxins11090495
Two garlic-derived compounds,...
Toxins, Vol. 11, Pages 493: A Novel Magnetic Molecular Imprinted Polymer for Selective Extraction of Zearalenone from Cereal Flours before Liquid Chromatography-Tandem Mass Spectrometry Determination
Toxins doi: 10.3390/toxins11090493
Giorgia La Barbera
Anna Laura Capriotti...
Available online 24 August 2019 Author(s): Peng Wang, Perng-Kuang Chang, Qing Kong, Shihua Shan, Qijian WeiAbstractAflatoxin production of Aspergillus flavus is affected by abiotic factors such as temperature, water activity, oxidative stress, etc. These factors likely affect different metabolic pathways and result in altered aflatoxin production. Aflatoxin was determined in liquid media at 28 °C...
Available online 22 August 2019 Author(s): Jianglin Xiong, Lijuan Peng, Hualin Zhou, Bo Lin, Pingyu Yan, Wenxuan Wu, Yulan Liu, Lingying Wu, Yinsheng QiuAbstractThe objective of this study was to survey the prevalence of aflatoxin M1 (AFM1) in raw, pasteurized, extended shelf life (ESL) and UHT milk from central-south China. A total of 734 milk samples, comprising raw milk (133 samples),...
Available online 7 August 2019 Author(s): Mohamed F. Abdallah, Kris Audenaert, Leonie Lust, Sofie Landschoot, Boris Bekaert, Geert Heasaert, Marthe De Boevre, Sarah De SaegerAbstractSugarcane juice is a traditional drink consumed on a daily basis in Egypt. The current work was conducted to (1) evaluate the multi-mycotoxin contamination in sugarcane juice, (2) identify the profiles of the...
Publication date: Available online 20 August 2019 Food and Chemical ToxicologyAuthor(s): Yanju Xiao, Bingjie Liu, Zijuan Wang, Chenlu Han, Xianghong Meng, Fang ZhangAbstractPorcine pancreatic lipase (PPL) was used to degrade the mycotoxin patulin (PAT) in pear juice. The dosage of PPL, the initial concentration of PAT, reaction temperature and time were investigated by batch experiments to study...
Recently, it was reported that ochratoxin A (OTA) mycotoxin, produced by a number of Aspergillus and Penicillium fungal species, may cause neuropsychological impairment or mental and emotional disorders but the mechanism of neurotoxicity remains unknown. Adverse effects of OTA in human (SHSY5Y) and mouse (HT22) neuronal cell lines were studied in vitro. OTA was found to...
Production of aflatoxin by Aspergillus flavus in peanuts is both a health hazard and major problem. This study investigated the ability of a whey protein concentrate (WPC)‐based edible coating containing Williopsis saturnus var. saturnus to prevent growth of A. flavus and aflatoxin production in peanuts. WPC with/without W. saturnus (7 log colony‐forming unit [CFU]/g) or W. saturnus...
Available online 19 August 2019 Author(s): Usman Rasheed, Hao Wu, Jinfan Wei, Xiaoyun Ou, Peisheng Qin, Xiaohua Yao, Han Chen, Amanda Juan Chen, Bin LiuAbstractAspergillus section Flavi is widely known as a potential threat to contaminate agricultural products and food commodities. In this study, a polyphasic approach consisting of micro- and macro-morphological, chemical and molecular features,...
Toxins, Vol. 11, Pages 481: Biotransformation of the Mycotoxin Zearalenone to its Metabolites Hydrolyzed Zearalenone (HZEN) and Decarboxylated Hydrolyzed Zearalenone (DHZEN) Diminishes its Estrogenicity In Vitro and In Vivo
Toxins doi: 10.3390/toxins11080481
Toxins, Vol. 11, Pages 476: Impact of Naturally Contaminated Substrates on Alphitobius diaperinus and Hermetia illucens: Uptake and Excretion of Mycotoxins
Toxins doi: 10.3390/toxins11080476
Insects are considered a suitable alternative feed for livestock...
Publication date: Available online 15 August 2019 Innovative Food Science & Emerging TechnologiesAuthor(s): Hiba N. Rajha, Anna-Maria Abi Khattar, Sally El Kantar, Nadia Boussetta, Nikolai Lebovka, Richard G. Maroun, Nicolas Louka, Eugene VorobievAbstractThe effects of aqueous extraction of bioactive compounds from pomegranate peels using conventional extraction (CE) and extraction assisted...
A biochip chemiluminescent immunoassay was validated for multi-mycotoxins screening in maize. Screened mycotoxins were aflatoxins B1 (AFB1) and G1 (AFG1) ochratoxin A (OTA), zearalenone (ZEA), toxin T2 (T2), fumonisins (sum of FB1 and FB2) and deoxynivalenol (DON). The method included a single extraction step with acetonitrile:methanol:water (50:40:10, v/v/v). Spiked samples...
Jisoo Lee, Shinae Kim, Hye-mi Kim, Hyun Jeong Kim, Frank H. Yu
ND7/23 cells are gaining traction as a host model to express peripheral sodium channels such as NaV1.8 and NaV1.9 that have been difficult to express in widely utilized heterologous cells, like CHO and HEK293. Use of ND7/23 as a model cell to characterize the properties of sodium channels requires clear understanding of the...
Journal of Food Protection, Volume 82, Issue 9, Page 1472-1478, September 2019.
Publication date: Available online 10 August 2019 Food and Chemical ToxicologyAuthor(s): Luísa Freire, Marianna M. Furtado, Tatiane M. Guerreiro, Juliana S. da Graça, Beatriz S. da Silva, Diogo N. Oliveira, Rodrigo R. Catharino, Anderson S. Sant’AnaAbstractYeasts are able to reduce the levels of ochratoxin A in fermentative processes; and, through their enzymatic complex, these micro-organisms...
Toxins, Vol. 11, Pages 471: Determination of Ochratoxin A (OTA), Ochratoxin B (OTB), T-2, and HT-2 Toxins in Wheat Grains, Wheat Flour, and Bread in Lebanon by LC-MS/MS
Toxins doi: 10.3390/toxins11080471
Amira Al Matari
Cereals are prone to fungal infection during growth, harvesting, transportation, and/or storage....
Available online 9 August 2019 Author(s): Lourdes Sánchez-Montero, Juan J. Córdoba, Alberto Alía, Belén Peromingo, Félix NúñezAbstractEnvironmental conditions during ripening of dry-cured meat products favour growth of fungal population on their surface. Some of these moulds can produce mycotoxins. Paprika is one of the ingredients usually used in the formulation of raw-cured sausages, and its...
Toxins, Vol. 11, Pages 469: Aflatoxin Exposure from Milk in Rural Kenya and the Contribution to the Risk of Liver Cancer
Toxins doi: 10.3390/toxins11080469
Anima J. Sirma
Johanna F. Lindahl
Milk is an important commodity in Kenya; the country has the largest dairy herd and highest per capita milk consumption in East Africa. As such...
An automated optical biosensor-based immunoassay exploiting surface plasmon resonance detection for the quantitation of aflatoxin M1 (AFM1) in milk and milk powders is described. A monoclonal antibody and an immobilized protein–AFM1 conjugate are utilized in a simple inhibition format following aqueous extraction and immunoaffinity clean-up of the sample, thereby avoiding the...
Toxins, Vol. 11, Pages 470: Contrasting Toxin Selectivity between the Marine Pufferfish Takifugu pardalis and the Freshwater Pufferfish Pao suvattii
Toxins doi: 10.3390/toxins11080470
To clarify the differences in toxin selectivity between marine and...
Toxins, Vol. 11, Pages 468: Paralytic Shellfish Toxin Uptake, Assimilation, Depuration, and Transformation in the Southeast Asian Green-Lipped Mussel (Perna viridis)
Toxins doi: 10.3390/toxins11080468
John Kristoffer Andres
Aletta T. Yñiguez
Jennifer Mary Maister
Andrew D. Turner
Dave Eldon B. Olano
Rhodora V. Azanza
Toxins, Vol. 11, Pages 467: Genetic Profiling of Aspergillus Isolates with Varying Aflatoxin Production Potential from Different Maize-Growing Regions of Kenya
Toxins doi: 10.3390/toxins11080467
Richard Dooso Oloo
Jean-Baka Domelevo Entfellner
Highly toxigenic strains...
Wild fruits are an important food and income source for many households in Zambia. Non-cultivated plants may be as susceptible as crops to aflatoxin contamination. Concentrations of aflatoxins in commonly consumed wild fruits from markets and characteristics of associated aflatoxin-producers need to be determined to assess the aflatoxin risk posed by handling, processing, storage and consumption...
Publication date: Available online 10 July 2019Source: Author(s): Edmund D. Brodie
Toxins, Vol. 11, Pages 463: Investigation of Zearalenone Adsorption and Biotransformation by Microorganisms Cultured under Cellular Stress Conditions
Toxins doi: 10.3390/toxins11080463
The zearalenone binding and metabolization ability of probiotic microorganisms, such as lactic acid bacteria,...
Publication date: Available online 2 August 2019 Food and Chemical ToxicologyAuthor(s): Shruti Shukla, Jong Suk Lee, Vivek K. Bajpai, Imran Khan, Yun Suk Huh, Young-Kyu Han, Myunghee KimAbstractThe present study aimed to develop a consortium of nutritive fermented food products, supplemented with phytochemicals, with reduced toxicological contents. We developed new flavored Doenjang products (...