Natural toxins

Mon, 07/01/2019 - 00:00
As patulin is a kind of mycotoxin commonly found in fruit products, it is of great importance to develop simple and accurate analytical methods for the sensitive detection of patulin (PAT). In this work, based on molecular imprinted polymer (MIP) and surface-enhanced Raman scattering (SERS) technique, a specific and sensitive PAT sensor was developed. To prepare the MIP-SERS...
Mon, 07/01/2019 - 00:00
Abstract Peanuts with fungal contamination may contain aflatoxin, a highly carcinogenic substance. We propose the use of hyperspectral imaging to quickly and noninvasively identify fungi-contaminated peanuts. The spectral data and spatial information of hyperspectral images were exploited to improve identification accuracy. In addition, successive projection was adopted to...
Sun, 06/30/2019 - 00:00
Toxins, Vol. 11, Pages 378: Pig Urinary Concentration of Mycotoxins and Metabolites Reflects Regional Differences, Mycotoxin Intake and Feed Contaminations Toxins doi: 10.3390/toxins11070378 Authors: Lucia Gambacorta Monica Olsen Michele Solfrizzo The determination of mycotoxin and metabolite concentrations in human and animal urine is currently used for risk assessment and mycotoxin...
Sat, 06/29/2019 - 00:00
Toxins, Vol. 11, Pages 377: Ochratoxin A-Induced Hepatotoxicity through Phase I and Phase II Reactions Regulated by AhR in Liver Cells Toxins doi: 10.3390/toxins11070377 Authors: Hye Soo Shin Hyun Jung Lee Min Cheol Pyo Dojin Ryu Kwang-Won Lee Ochratoxin A (OTA) is a widespread mycotoxin produced by several species of the genera Aspergillus and Penicillium. OTA exists in a variety...
Thu, 06/27/2019 - 01:07
Publication date: Available online 25 June 2019Source: Author(s): Jingyuan Yao, Wei Jin, Dongmei Li, Daoyan Xu, Shiyong Wen, Renyan Liu, Yubo Liang, Songhui LuAbstractParalytic shellfish toxins (PSTs) are a group of the most harmful neurotoxins distributed worldwide. Marine organism samples, including mollusks, crustaceans and fish, collected from 11 sites around the coastal water of the South...
Thu, 06/27/2019 - 00:00
Toxins, Vol. 11, Pages 375: Global Mycotoxin Occurrence in Feed: A Ten-Year Survey Toxins doi: 10.3390/toxins11070375 Authors: Christiane Gruber-Dorninger Timothy Jenkins Gerd Schatzmayr Mycotoxins contaminating animal feed can exert toxic effects in animals and be transferred into animal products. Therefore, mycotoxin occurrence in feed should be monitored. To this end, we performed...
Wed, 06/26/2019 - 01:12
Publication date: September 2019 Food and Chemical Toxicology, Volume 131Author(s): Hans Steinkellner, Marco Binaglia, Chiara Dall'Asta, Arno C. Gutleb, Manfred Metzler, Isabelle P. Oswald, Dominique Parent-Massin, Jan AlexanderAbstractThis paper describes a methodology for hazard assessment of groups of related substances for which toxicity data are insufficient, and which utilises, next to...
Mon, 06/24/2019 - 20:00
Controlling aflatoxigenic Aspergillus flavus (Af) and aflatoxins in grains and food during storage are great challenge to humans worldwide. Alcaligenes faecalis N1-4 isolated from tea rhizosphere soil can produce abundant antifungal volatiles, and greatly inhibited the growth of Af in un-contacted face-to-face dual culture tests. Gas chromatography tandem mass spectrometry revealed that dimethyl...
Mon, 06/24/2019 - 20:00
Aflatoxin B1 (AfB1) is a carcinogenic mycotoxin that contaminates food and feed worldwide. We determined the AfB1-adsorption capability of non-viable Pleurotus eryngii mycelium, an edible fungus, as a potential means for removal of AfB1 from contaminated solutions. Lyophilized mycelium was produced and made enzymatically inert by sterilization at high temperatures . The material thus obtained...
Mon, 06/24/2019 - 08:33
Abstract The purpose of this study was to assess the risk of zearalenone (ZEA) in corn meal produced and commercialized in State of Parana, Brazil. The extraction method carried out with a Romer Mycosep 226 column was found to be efficient due to addition of both diatomaceous earth and centrifuging during the cleaning step. From the total of 84 analyzed samples, 78.6% (n = 66) were found to be...
Mon, 06/24/2019 - 03:00
Journal of Food Protection, Volume 82, Issue 7, Page 1176-1182, July 2019.
Sun, 06/23/2019 - 01:07
Publication date: 15 November 2019 , Volume 298Author(s): Jinghua Wu, Lingwen Zeng, Nianlong Li, Chengshuai Liu, Junhua ChenAbstractA wash-free and label-free colorimetric biosensor for the amplified detection of aflatoxin B1 (AFB1) has been constructed by the integration of an ingenious hairpin DNA probe with exonuclease III (Exo III)-assisted signal amplification. The presence of the AFB1...
Thu, 06/20/2019 - 01:12
Available online 18 June 2019 Author(s): An-Dong Gong, Fei-Yan Dong, Meng-Jun Hu, Xian-Wei Kong, Fen-Fen Wei, Shuang-Jun Gong, Yi-Mei Zhang, Jing-Bo Zhang, Ai-Bo Wu, Yu-Cai LiaoAbstractThe contamination of food with Aspergillus flavus and subsequent aflatoxins is considered as one of the most severe safety problems in the world. The application of microorganisms and the produced bio-active...
Thu, 06/20/2019 - 01:12
Available online 18 June 2019 Author(s): Jomana Elaridi, Hani Dimassi, Hussein HassanAbstractAflatoxin M1 (AFM1) and ochratoxin A (OTA) are hepatotoxin and nephrotoxin mycotoxins, respectively. An investigation on their presence in baby formulae marketed in Lebanon was conducted. Infant formula samples were collected from 42 brands over two production dates (n = 84) during 2017–2018 and analyzed...
Thu, 06/20/2019 - 01:06
LWT
Publication date: Available online 7 June 2019Source: LWTAuthor(s): Sofía Sampaolesi, Raúl Ricardo Gamba, Graciela Liliana De Antoni, Ángela María León PeláezAbstractBeer is the most consumed alcoholic beverage worldwide and brewery is a growing industry. Biomass by-product of beer production is constituted by viable and non-viable flocculated yeasts which are discarded. To increase the value of...
Wed, 06/19/2019 - 05:29
Abstract This study aimed to evaluate the ability of the Lactobacillus rhamnosus strain LC‐4 to bind aflatoxin M1 (AFM1) in phosphate‐buffered saline (PBS) and yogurt. Bacterial cells were subjected to heat, acid, and alkali treatments. The AFM1‐binding rate of acid‐treated bacteria was of 78.63 ± 0.52%. The binding of L. rhamnosus LC‐4 to AFM1 was partially reversible and the binding of AFM1...
Wed, 06/19/2019 - 01:16
Publication date: Available online 17 June 2019 Food and Chemical ToxicologyAuthor(s): Qin Zhao, Zhao-Si Yang, San-Jie Cao, Yung-Fu Chang, Yu-Qin Cao, Jia-Bing Li, Zi-Xuan Yao, Yi-Ping Wen, Xiao-Bo Huang, Rui Wu, Qi-Gui Yan, Yong Huang, Xiao-Ping Ma, Xin-Feng Han, Yinglong WuAbstractCadmium and aflatoxin B1 (AFB1) are both common and widespread pollutants in food and feed. There are several...
Mon, 06/17/2019 - 13:44
Abstract The detoxification ability of Lactobacillus acidophilus and prebiotics was evaluated by a Plackett‐Burman Design to examine the reduction of concentration and bioaccessibility of aflatoxin B1 (AFB1) and M1 (AFM1) in artificially contaminated whole cow's milk. Six variables were evaluated: AFB1 (3.25–6.0 μg L−1) or AFM1 (1.0–2.0 μg L−1) concentration; incubation time (0–6 h); and inulin,...
Sun, 06/16/2019 - 01:12
Available online 14 June 2019 Author(s): Takashi Yarita, Shinsuke Inagaki, Ayano Miyamoto, Taichi Yamazaki, Migaku Kawaguchi, Hajime Uchida, Akiko Takatsu, Toshiyuki SuzukiAbstractA scallop midgut gland certified reference material, NMIJ CRM 7520-a, was developed for validation and quality assurance during the inspection of shellfish for diarrhetic shellfish toxins. The candidate material was...
Sat, 06/15/2019 - 00:00
Toxins, Vol. 11, Pages 342: Occurrence of Mycotoxins in Swine Feeding from Spain Toxins doi: 10.3390/toxins11060342 Authors: Natalia Arroyo-Manzanares Vicente Rodríguez-Estévez Plácido Arenas-Fernández Ana M. García-Campaña Laura Gámiz-Gracia A survey including 228 pig feed samples from Spain has been developed, exploring the occurrence of 19 mycotoxins (aflatoxins B1, B2, G1 and...
Fri, 06/14/2019 - 01:06
LWT
Publication date: September 2019Source: LWT, Volume 112Author(s): Tiago de Melo Nazareth, Juan Manuel Quiles, Raquel Torrijos, Fernando Bittencourt Luciano, Jordi Mañes, Giuseppe MecaAbstractThe present study evaluated the efficacy of allyl isothiocyanate (AITC) in avoiding the growth of Penicillium verrucosum and consequent ochratoxin A (OTA) production in barley during storage for 90 d....
Fri, 06/14/2019 - 00:00
Toxins, Vol. 11, Pages 341: Cytotoxicity, Genotoxicity and Disturbance of Cell Cycle in HepG2 Cells Exposed to OTA and BEA: Single and Combined Actions Toxins doi: 10.3390/toxins11060341 Authors: Juan-García Tolosa Juan Ruiz Mycotoxins are produced by a number of fungal genera spp., for example, Aspergillus, Penicillium, Alternaria, Fusarium, and Claviceps. Beauvericin (BEA) and...
Thu, 06/13/2019 - 00:00
Toxins, Vol. 11, Pages 337: Cold Plasma Treatment as an Alternative for Ochratoxin a Detoxification and Inhibition of Mycotoxigenic Fungi in Roasted Coffee Toxins doi: 10.3390/toxins11060337 Authors: Paloma Patricia Casas-Junco Josué Raymundo Solís-Pacheco Juan Arturo Ragazzo-Sánchez Blanca Rosa Aguilar-Uscanga Pedro Ulises Bautista-Rosales Montserrat Calderón-Santoyo Ochratoxin...
Wed, 06/12/2019 - 00:00
Toxins, Vol. 11, Pages 333: Effects of Dietary Zearalenone on Oxidative Stress, Cell Apoptosis, and Tight Junction in the Intestine of Juvenile Grass Carp (Ctenopharyngodon idella) Toxins doi: 10.3390/toxins11060333 Authors: Ya-Li Wang Xiao-Qiu Zhou Wei-Dan Jiang Pei Wu Yang Liu Jun Jiang Shang-Wen Wang Sheng-Yao Kuang Ling Tang Lin Feng Zearalenone (ZEA) is a prevalent...
Tue, 06/11/2019 - 00:00
Toxins, Vol. 11, Pages 331: Occurrence of Tetrodotoxin in Bivalves and Gastropods from Harvesting Areas and Other Natural Spaces in Spain Toxins doi: 10.3390/toxins11060331 Authors: Lucía Blanco Jorge Lago Virginia González Beatriz Paz Maria Rambla-Alegre Ana G. Cabado Tetrodotoxin (TTX) is a potent neurotoxin that is receiving increasing interest in the European Union because...
Sat, 06/08/2019 - 01:13
Available online 4 June 2019 Author(s): Suyan Qiu, Lijuan Yuan, Yihua Wei, Dawen Zhang, Qinglong Chen, Zhenyu Lin, Linguang LuoAbstractA novel signal-on portable sensing system has been developed for OTA detection using personal glucose meter (PGM) as signal transducer. In the study, we explore the potential of using a short dsDNA as template to trigger the “click” ligation of two DNA strands,...
Sat, 06/08/2019 - 00:00
Toxins, Vol. 11, Pages 329: Occurrence of the Ochratoxin A Degradation Product 2′R-Ochratoxin A in Coffee and Other Food: An Update Toxins doi: 10.3390/toxins11060329 Authors: Franziska Sueck Vanessa Hemp Jonas Specht Olga Torres Benedikt Cramer Hans-Ulrich Humpf Food raw materials can contain the mycotoxin ochratoxin A (OTA). Thermal processing of these materials may result in...
Sat, 06/08/2019 - 00:00
Toxins, Vol. 11, Pages 330: Application of Zearalenone (ZEN)-Detoxifying Bacillus in Animal Feed Decontamination through Fermentation Toxins doi: 10.3390/toxins11060330 Authors: Shiau-Wei Chen Han-Tsung Wang Wei-Yuan Shih Yan-An Ciou Yu-Yi Chang Laurensia Ananda Shu-Yin Wang Jih-Tay Hsu Zearalenone (ZEN) is an estrogenic mycotoxin which can cause loss in animal production....
Fri, 06/07/2019 - 00:00
Toxins, Vol. 11, Pages 328: Fumonisins: Impact on Agriculture, Food, and Human Health and their Management Strategies Toxins doi: 10.3390/toxins11060328 Authors: Madhu Kamle Dipendra K. Mahato Sheetal Devi Kyung Eun Lee Sang G. Kang Pradeep Kumar The fumonisins producing fungi, Fusarium spp., are ubiquitous in nature and contaminate several food matrices that pose detrimental...
Thu, 06/06/2019 - 01:12
Publication date: Available online 5 June 2019 Food and Chemical ToxicologyAuthor(s): Tongtong Shen, Yufan Miao, Chenchen Ding, Wentao Fan, Shuhui Liu, Yanan Lv, Xiaona Gao, Marthe De Boevre, Liping Yan, Sheila Okoth, Sarah De Saeger, Suquan SongAbstractZearalenone (ZEA) can widely contaminate crops and agricultural products. The ingestion of ZEA-contaminated food or feed affects the integrity...
Wed, 06/05/2019 - 01:12
Available online 3 June 2019 Author(s): Josué Delgado, Félix Núñez, Miguel A. Asensio, Rebecca A. OwensAbstractDry-cured meat products are usually contaminated with moulds during ripening. Although fungal development contributes to the desired sensory characteristics, some moulds, such as Penicillium nordicum are able to produce ochratoxin A (OTA) on meat products. Therefore, strategies to...
Mon, 06/03/2019 - 00:00
Abstract Application of atoxigenic strains to compete against toxigenic strains of Aspergillus flavus strains has emerged as one of the practical strategies for reducing aflatoxin contamination in corn, peanut, and tree nuts. The actual mechanism that results in aflatoxin reduction is not fully understood. Real-time RT-PCR and relative quantification of gene expression protocol...
Mon, 06/03/2019 - 00:00
Toxins, Vol. 11, Pages 315: Mitigating Aflatoxin Contamination in Groundnut through A Combination of Genetic Resistance and Post-Harvest Management Practices Toxins doi: 10.3390/toxins11060315 Authors: Manish K. Pandey Rakesh Kumar Arun K. Pandey Pooja Soni Sunil S. Gangurde Hari K. Sudini Jake C. Fountain Boshou Liao Haile Desmae Patrick Okori Xiaoping Chen Huifang...
Sat, 06/01/2019 - 01:12
Publication date: Available online 30 May 2019 Food and Chemical ToxicologyAuthor(s): Jochem Louisse, Deborah Rijkers, Geert Stoopen, Wendy Jansen Holleboom, Mona Delagrange, Elise Molthof, Patrick P.J. Mulder, Ron L.A.P. Hoogenboom, Marc Audebert, Ad A.C.M. PeijnenburgAbstractPyrrolizidine alkaloids (PAs) are secondary metabolites from plants that have been found in substantial amounts in herbal...
Sat, 06/01/2019 - 00:00
Abstract Recent studies from our laboratory indicate that engineered silver nanoparticles can inhibit aflatoxin biosynthesis even at concentrations at which they do not demonstrate antifungal activities on the aflatoxin-producing fungus. Whether such inhibition can be modified by altering the nanoparticles’ physical properties remains unclear. In this study, we demonstrate...
Fri, 05/31/2019 - 01:12
Available online 28 May 2019 Author(s): Xianfeng Ren, Qi Zhang, Wenhua Wu, Tingting Yan, Xiaoqian Tang, Wen Zhang, Li Yu, Peiwu LiAbstractAn anti-idiotypic nanobody-phage display-mediated immuno-polymerase chain reaction (PD-IPCR) method was developed for simultaneous quantitative detection of total aflatoxins and zearalenone in cereals. Two phages, displaying the variable domain of the heavy...
Fri, 05/31/2019 - 01:12
Available online 29 May 2019 Author(s): Ling Guo, Yanyan Wang, Peng Fei, Jianxin Liu, Daxi RenABSTRACTThe objective of this study was to investigate the levels of aflatoxin M1 (AFM1) concentration in raw milk and dairy products from water buffalo in south China. 136 raw milk and 86 dairy products samples were collected randomly from buffalo dairy pastures and supermarket in Guangxi, Guizhou,...
Fri, 05/31/2019 - 00:00
Toxins, Vol. 11, Pages 312: Mycotoxins at the Start of the Food Chain in Costa Rica: Analysis of Six Fusarium Toxins and Ochratoxin A between 2013 and 2017 in Animal Feed and Aflatoxin M1 in Dairy Products Toxins doi: 10.3390/toxins11060312 Authors: Andrea Molina Guadalupe Chavarría Margarita Alfaro-Cascante Astrid Leiva Fabio Granados-Chinchilla Mycotoxins are secondary...
Thu, 05/30/2019 - 00:00
Toxins, Vol. 11, Pages 309: Separation and Purification of Aflatoxins by Centrifugal Partition Chromatography Toxins doi: 10.3390/toxins11060309 Authors: Gábor Endre Zsófia Hegedüs Adiyadolgor Turbat Biljana Škrbić Csaba Vágvölgyi András Szekeres Aflatoxins are mycotoxins that are produced by several species of filamentous fungi. In the European Union, the concentration limits...
Thu, 05/30/2019 - 00:00
Toxins, Vol. 11, Pages 308: Occurrence of Deoxynivalenol and Ochratoxin A in Beers and Wines Commercialized in Paraguay Toxins doi: 10.3390/toxins11060308 Authors: Andrea Alejandra Arrúa Juliana Moura Mendes Pablo Arrúa Francisco Paulo Ferreira Gabriela Caballero Cinthia Cazal Man Mohan Kohli Inocencia Peralta Gabriela Ulke Danilo Fernández Ríos Alcoholic beverages can...
Wed, 05/29/2019 - 00:00
Toxins, Vol. 11, Pages 306: Tetrodotoxins Occurrence in Non-Traditional Vectors of the North Atlantic Waters (Portuguese Maritime Territory, and Morocco Coast) Toxins doi: 10.3390/toxins11060306 Authors: Marisa Silva Inés Rodríguez Aldo Barreiro Manfred Kaufmann Ana Isabel Neto Meryem Hassouani Brahim Sabour Amparo Alfonso Luis M. Botana Vitor Vasconcelos Tetrodotoxin (...
Wed, 05/29/2019 - 00:00
Toxins, Vol. 11, Pages 305: Acute Toxicity Assessment: Macroscopic and Ultrastructural Effects in Mice Treated with Oral Tetrodotoxin Toxins doi: 10.3390/toxins11060305 Authors: Paula Abal M. Carmen Louzao Natalia Vilariño Mercedes R. Vieytes Luis M. Botana Tetrodotoxin (TTX) is an extremely toxic marine compound produced by different genera of bacteria that can reach humans...
Wed, 05/29/2019 - 00:00
Toxins, Vol. 11, Pages 304: Assorted Methods for Decontamination of Aflatoxin M1 in Milk Using Microbial Adsorbents Toxins doi: 10.3390/toxins11060304 Authors: Jean Claude Assaf Sahar Nahle Ali Chokr Nicolas Louka Ali Atoui André El Khoury Aflatoxins (AF) are carcinogenic metabolites produced by different species of Aspergillus which readily colonize crops. AFM1 is secreted in...
Mon, 05/27/2019 - 00:00
Toxins, Vol. 11, Pages 301: Degrading Ochratoxin A and Zearalenone Mycotoxins Using a Multifunctional Recombinant Enzyme Toxins doi: 10.3390/toxins11050301 Authors: Md Shofiul Azam Dianzhen Yu Na Liu Aibo Wu Zearalenone (ZEA) is an estrogenic and ochratoxin A (OTA) is a hepatotoxic Fusarium mycotoxin commonly seen in cereals and fruits products. No previous investigation has studied...
Sun, 05/26/2019 - 01:13
Publication date: Available online 24 May 2019 Food and Chemical ToxicologyAuthor(s): Nurshad Ali, Gisela H. DegenAbstractThe Fusarium toxin zearalenone (ZEN) is of concern due to its pronounced estrogenic effects in mammalian species. ZEN contaminates various cereal crops and grain-based food along with modified forms which contribute to overall mycoestrogen exposure. As no data exist on the...
Sun, 05/26/2019 - 01:12
Publication date: 15 October 2019 , Volume 295Author(s): Maria Carla CraveroAbstractThis review collates the scientific literature regarding organic and biodynamic wines. It concerns techniques that allow organic or biodynamic wines to be distinguished from conventional products. Other aspects of the organic wines addressed include the antioxidant capacities and the content of compounds...
Sat, 05/25/2019 - 01:12
Publication date: Available online 23 May 2019 Food and Chemical ToxicologyAuthor(s): Cathy Lester, John Troutman, Cindy Obringer, Ken Wehmeyer, Peter Stoffolano, Michael Karb, Yan Xu, Amy Roe, Greg Carr, Karen Blackburn, Catherine MahonyAbstract1,2-Unsaturated pyrrolizidine alkaloids (PAs) are sometimes present in foods or herbal supplements/medicines as impurities and pose potential concerns...
Fri, 05/24/2019 - 00:00
Toxins, Vol. 11, Pages 296: Time-Dependent Changes in the Intestinal Microbiome of Gilts Exposed to Low Zearalenone Doses Toxins doi: 10.3390/toxins11050296 Authors: Katarzyna Cieplińska Magdalena Gajęcka Michał Dąbrowski Anna Rykaczewska Sylwia Lisieska-Żołnierczyk Maria Bulińska Łukasz Zielonka Maciej T. Gajęcki Zearalenone is a frequent contaminant of cereals and their by...

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