Research Publications from Peer-Reviewed Journals

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Sat, 11/28/2020 - 22:08
Cephalosporins are, after penicillins, the most important β‐lactam inductors of immediate allergic reactions. Their antigenic determinants are not completely identified due to difficulties for studying the structure of cephalosporin‐protein conjugates, hampering the existence of in vitro tests with enough sensitivity to detect cephalosporin allergy.1 Therefore, the only diagnostic standardised...
Sat, 11/28/2020 - 18:01
Although melamine exposure induces cognitive deficits and dysfunctional neurotransmission in hippocampal Cornus Ammonis (CA) 1 region of rats, it is unclear whether the neural function, such as neural oscillations between hippocampal CA3–CA1 pathway and postsynaptic receptors involves in these effects. The levels of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor (AMPAR)...
Sat, 11/28/2020 - 14:06
High levels of lead (Pb) in the soil is a serious issue in the city of Kabwe, Zambia. Phytoremediation is an effective approach to revive the life-supporting functions of the soils. Locally available soil amendments, such as chicken manure, can strengthen phytoremediation. This study aims to find an appropriate combination of a locally available Pb hyperaccumulator, lemongrass (Cymbopogon...
Sat, 11/28/2020 - 14:04
Fresh foods like fruits, vegetables and shellfish are potential sources for viral infections such as human norovirus (NoV). Chemical treatment like chlorination is a well-known process for food pathogens and virus elimination. However, with the increase of the consumer demand for less toxic treatment, the use of natural antimicrobials like essential oils from spice or plants, fruit extracts, and...
Sat, 11/28/2020 - 06:19
Author(s): Benjamin R. Robinson, Dennis J. D’Amico Hydrogen peroxide (H2O2) has a long history of use as an antimicrobial in the dairy industry to preserve raw milk. The effect of H2O2 on the survival of Listeria monocytogenes on the surface of Queso Fresco (QF) and the degradation of H2O2 on cheese during storage and in dip solutions following successive treatments were determined. Treatment of...
Sat, 11/28/2020 - 06:14
Author(s): Donato Magistà, Giuseppe Cozzi, Lucia Gambacorta, Antonio F. Logrieco, Michele Solfrizzo, Giancarlo Perrone Ochratoxin A (OTA) occurrence in grapes is caused by black Aspergilli (Aspergillus carbonarius followed by A. niger) vineyards contamination. It depends on climatic conditions, geographical regions, damage by insects, and grape varieties. Good agricultural practices, pesticides,...
Sat, 11/28/2020 - 06:12
Author(s): Arunmozhimaran Elavarasi, Vinay Goyal Hemi-facial spasm (HFS) is an off label but well-accepted indication for Botulinum neurotoxin (BoNT) therapy(Berardelli et al., 1997). BoNT has been used widely over the past few decades and has an excellent safety record. However, there are instances when patients with no neuromuscular disorders have developed symptoms of asthenia, dysphagia,...
Sat, 11/28/2020 - 04:01
Bentonite clays exhibit high adsorptive capacity for contaminants and is frequently used as a feed additive to reduce the bioavailability and thus the toxicity of several mycotoxins. Zearalenone (ZEN) is a secondary Fusarium toxic metabolite that can contaminate a wide range of food- and feedstuff. Since organophilic treatments is known to increase the adsorption capacity of bentonites, the aim...
Sat, 11/28/2020 - 02:02
Hospital wastewater is regarded as a primary and very important source of antibiotics in the aquatic environment. Studies on the analysis, occurrence, and ecological risk assessment of fluoroquinolone antibiotics in wastewater are still limited in Africa. A quick, easy, cheap, effective, rugged, and safe extraction method was optimized and applied for determination of three fluoroquinolone...
Sat, 11/28/2020 - 02:01
The rapid growth of human population and global industrialization has resulted in the generation of larger amounts of wastewater containing various pollutants, among which toxic heavy metals. Adsorption is efficient for this purpose, but its application is limited by the high cost of adsorbent materials. Chitosan (CS) and phosphorylated microcellulose (PMC) have a high potential as low-cost and...
Sat, 11/28/2020 - 00:00
This study was conducted to investigate human exposure to 19 compounds (mycotoxins and their metabolites) in plasma samples from healthy adults (n = 438, aged 19–68 years) from Navarra, a region of northern Spain. Samples were analyzed by LC-MS/MS, before and after enzymatic hydrolysis for the detection of possible glucuronides and/or sulfates (Phase II metabolites). The most prevalent...
Sat, 11/28/2020 - 00:00
Pomegranate, similar to other fruits, has juice-extraction by-products. Pomegranate seed oil (PGO) is a non-traditional oil with health benefits, rich in bioactive components. This study was aimed to assess PGO phytochemicals and their influence as bioactive components to reduce mycotoxin secretion. The encapsulation was applied in micro and nanoforms to protect the quality and enhance the...
Sat, 11/28/2020 - 00:00
Probiotics have been shown to bind to host receptors, which are important for pathogen adhesion and induce the host’s production of defence factors. They can activate the goblet-cell-derived production of mucins, a major component of the mucus layer and a physical barrier participating in limiting the proximity of microorganisms to the epithelial layer. In the last decade, Bacillus spp...
Sat, 11/28/2020 - 00:00
The increased use of antibiotics in food animals has resulted in the selection of drug-resistant bacteria across the farm-to-fork continuum. This study aimed to investigate the molecular epidemiology of antibiotic-resistant Escherichia coli from intensively produced poultry in the uMgungundlovu District, KwaZulu-Natal, South Africa. Samples were collected weekly between August and September 2017...
Fri, 11/27/2020 - 16:00
The family Pentatomidae (Hemiptera: Heteroptera) includes several invasive stink bug species capable to attack a large number of wild and cultivated plants, causing several damages to different crops. Pentatomids rely on obligate symbiotic associations with bacteria of the family Enterobacteriaceae, mainly of the genus Pantoea. A distinctive trait of these associations is the transmission route:...
Fri, 11/27/2020 - 16:00
The objectives of this study were to evaluate the inactivation efficacy of a 405-nm light-emitting diode (LED) against Cronobacter sakazakii biofilm formed on stainless steel and to determine the sensitivity change of illuminated biofilm to food industrial disinfectants. The results showed that LED illumination significantly reduced the population of viable biofilm cells, showing reduction of 2.0...
Fri, 11/27/2020 - 16:00
Suilysin (SLY) plays a critical role in Streptococcus suis infections making it an ideal target to the combat infection caused by this pathogen. In the present study, we found that piceatannol (PN), a natural compound, inhibits pore-formation by blocking the oligomerization of SLY without affecting the growth of S. suis and the expression of SLY. Furthermore, PN alleviated the J774 cell damage...
Fri, 11/27/2020 - 16:00
IncP-1 plasmids, first isolated from clinical specimens (R751, RP4), are recognized as important vectors spreading antibiotic resistance genes. The abundance of IncP-1 plasmids in the environment, previously reported, suggested a correlation with anthropogenic pollution. Unexpectedly, qPCR-based detection of IncP-1 plasmids revealed also an increased relative abundance of IncP-1 plasmids in total...
Fri, 11/27/2020 - 12:01
The opioid epidemic in the United States, along with a lack of adequate harm reduction services, has contributed to a sharp rise in hepatitis C virus (HCV) infections. Despite considerable evidence of the effectiveness of HCV treatment in people who inject drugs (PWID), and recommendations from clinical guidelines to prioritize treatment in PWID, there are multiple barriers to broad uptake of HCV...
Fri, 11/27/2020 - 06:09
Author(s): Lang Sun, Emily C. Forauer, Stephanie R.B. Brown, Dennis J. D'Amico Listeria monocytogenes can form persistent biofilms on food processing surfaces, resulting in cross-contamination of food products, including milk and milk products. Natural glycolipids are a promising intervention to control undesirable microbes due to their antimicrobial activity and low toxicity. This study aimed to...
Fri, 11/27/2020 - 06:08
Author(s): Lisa Goedtke, Andrea John, Alfonso Lampen, Albrecht Seidel, Albert Braeuning, Stefanie Hessel-Pras Carcinogenic benzo[a]pyrene (BP) and other non-carcinogenic polycyclic aromatic hydrocarbons (PAH) like fluoranthene (FA) and pyrene (PYR) occur as food contaminants. Molecular effects of BP, FA and PYR in human liver cells were investigated using mixtures occurring in grilled meat....
Fri, 11/27/2020 - 06:07
Author(s): Antuo Hu, Cancan Gao, Zhaoxin Lu, Fengxia Lu, Liangyu Kong, Xiaomei Bie To identify the main spoilage bacterium on fresh-cut leafy vegetables and establish a multiplex PCR assay.
Fri, 11/27/2020 - 04:02
Evolving antimicrobial resistance has motivated the search for novel targets and alternative therapies. Caseinolytic protease (ClpP) has emerged as an enticing new target since its function is conserved and essential for bacterial fitness, and because its inhibition or dysregulation leads to bacterial cell death. ClpP protease function controls global protein homeostasis and is, therefore,...
Fri, 11/27/2020 - 00:00
The extraordinarily potent clostridial neurotoxins (CNTs) comprise tetanus neurotoxin (TeNT) and the seven established botulinum neurotoxin serotypes (BoNT/A-G). They are composed of four structurally independent domains: the roles of the catalytically active light chain, the translocation domain HN, and the C-terminal receptor binding domain HCC are largely resolved, but that of the HCN domain...
Fri, 11/27/2020 - 00:00
Some nemertean species from the genus Cephalothrix accumulate tetrodotoxin (TTX) in extremely high concentrations. The current study is the first to provide high-performance liquid chromatography–tandem mass spectrometry (HPLC–MS/MS) data on tetrodotoxin and its analogues (TTXs) profile and concentration in different regions and organs of Cephalothrix cf. simula, and its...
Thu, 11/26/2020 - 22:06
This study aimed to observe the effects of Selenium (Se) on aflatoxin B1 (AFB1)‐induced uterine injury in female mice and necrosis of human endometrial microvascular endothelial cells (HEMECs). Fifty female mice were randomly divided into control group; AFB1 group; Se group (0.2 mg/kg each day); AFB1 + Se group; and positive control group. After continuous treatment for 30 days, uterine tissues...
Thu, 11/26/2020 - 22:06
Asarone isomers are naturally occurring in Acorus calamus Linné, Guatteria gaumeri Greenman, and Aniba hostmanniana Nees. These secondary plant metabolites belong to the class of phenylpropenes (phenylpropanoids or alkenylbenzenes). They are further chemically classified into the propenylic trans‐ and cis‐isomers α‐asarone and β‐asarone and the allylic γ‐asarone. Flavoring, as well as potentially...
Thu, 11/26/2020 - 18:01
Lead is a ubiquitous heavy metal toxin of significant public health concern. Every individual varies in their response to lead’s toxic effects due to underlying genetic variations in lead metabolizing enzymes or proteins distributed in the population. Earlier studies, including our lab, have attributed the influence of ALAD (δ-Aminolevulinate dehydratase) polymorphism on blood lead retention and...
Thu, 11/26/2020 - 16:00
Shiga toxin-producing Shigella species and Escherichia coli (STEC) are pathogenic bacteria that cause the bloody diarrheal diseases bacillary dysentery (Shigella spp.) and hemorrhagic colitis (STEC). Unfortunately, patients with these diarrheal diseases are at risk for developing potentially lethal extraintestinal complications such as hemolytic uremic syndrome (HUS), resulting in acute renal...
Thu, 11/26/2020 - 16:00
A Viable but non-culturable (VBNC) state is a bacterial survival strategy under reverse conditions. It poses a significant challenge for public health and food safety. In this study, the effect of external environmental conditions including acid, nutrition, and salt concentrations on the formation of S. aureus VBNC states at low temperatures were investigated. Different acidity and nutritional...
Thu, 11/26/2020 - 16:00
Molecular rapid diagnostic assays associated with antimicrobial stewardship have proven effective for the early adaptation of empiric therapy in bloodstream infections. The ePlex® BCID (GenMark Diagnostics) Panels allow identification of 56 bacteria and fungi and 10 resistance genes in 90 min directly from positive blood cultures. We prospectively evaluated 187 sepsis episodes at Grenoble...
Thu, 11/26/2020 - 16:00
The difference between left- and right-sided colon cancer has become the focus of global attention, and researchers have found differences in the morbidity, molecular biological characteristics, and response to targeted drug therapy between left- and right-sided colon cancer. Therefore, the identification of more effective predictive indicators is critical for providing guidance to future...
Thu, 11/26/2020 - 10:01
ABSTRACT Total biosynthesis or whole-cell biocatalytic production of sulfated small molecules relies on the discovery and implementation of appropriate sulfotransferase enzymes. Although fungi are prominent biocatalysts and have been used to sulfate drug-like phenolics, no gene encoding a sulfotransferase enzyme has been functionally characterized from these organisms. Here, we identify a...
Thu, 11/26/2020 - 10:01
ABSTRACT Although most of the approximately 94 million annual human cases of gastroenteritis due to Salmonella enterica resolve without medical intervention, antimicrobial therapy is recommended for patients with severe disease. Wild birds can be natural hosts of Salmonella that pose a threat to human health; however, multiple-drug-resistant serovars of S. enterica have rarely been described. In...
Thu, 11/26/2020 - 10:01
ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 40 million people worldwide, with over 1 million deaths as of October 2020 and with multiple efforts in the development and testing of antiviral drugs and vaccines under way. In order to gain insights into SARS-CoV-2 evolution and drug targets, we investigated how and to what extent the SARS-CoV-2 genome...
Thu, 11/26/2020 - 08:02
In the absence of an effective vaccine, the efficacy of antimalarial chemotherapies underpins the success of malaria control programmes. Artemisinin-based combination therapies (ACTs), which combine fast-acting artemisinin derivatives and longer-acting partner drugs, are the mainstay of treatment of uncomplicated falciparum malaria in endemic regions.1 However, as reported for almost all...
Thu, 11/26/2020 - 06:15
Author(s): Yizhi Tang, Yan Lai, Xingyuan Wang, Changwei Lei, Chao Li, Linghan Kong, Yulong Wang, Hongning Wang The optrA gene encodes an ABC-F protein which confers cross-resistance to oxazolidinones and phenicols, and its transmission has so far been associated with multiple transposable elements, including IS1216E, prophages, ICEs and Tn558. Here, we identified an optrA gene flanked by two...
Thu, 11/26/2020 - 06:15
Author(s): Jiyun Li, Yuqing Zhou, Dawei Yang, Shan Zhang, Zhiliang Sun, Yang Wang, Shaolin Wang, Congming Wu The prevalence and antimicrobial susceptibility of Clostridium perfringens (C. perfringens) in chickens and pigs were investigated in Beijing and Shanxi, China. In total, 322 C. perfringens (chicken n = 60 and pig n = 262) were obtained from 620 feces of chickens (n = 256) and pigs (n = ...
Thu, 11/26/2020 - 06:15
Author(s): Tong Bu, Feier Bai, Xinyu Sun, Yongming Tian, Meng Zhang, Shuang Zhao, Kunyi He, Xin Wang, Pei Jia, Li Wang A prussian blue nanocubes decomposition-assisted signal amplification strategy for competitive lateral flow immunoassay (PBNCD-SALFIA) was innovatively proposed to analyze aflatoxin B1 (AFB1) in foodstuffs. The signal was amplified on account of the PBNCs can degrade and fade...
Thu, 11/26/2020 - 06:13
Author(s): Mahmoud Ibrahim, Salah Zakaria, Abdel-Hamid I. Bazid, Walid H. Kilany, Mohamed A.Zain El-Abideen, Ahmed Ali In this study, two highly pathogenic avian influenza (HPAI) H5N8 viruses were isolated from chicken and geese in 2018 and 2019 (Chicken/ME-2018 and Geese/Egypt/MG4/2019). The hemagglutinin and neuraminidase gene analyses revealed their close relatedness to the clade-2.3.4.4b H5N8...
Thu, 11/26/2020 - 06:11
LWT
Author(s): Woo Bin Hyun, Hai Seong Kang, Jae Won Lee, Haftom Baraki Abraha, Kwang-Pyo Kim Previous studies on Bacillus subtilis-producing bacteriocins (or bacteriocin-like inhibitory substance, BLIS) against Clostridium perfringens provided with limited information to show their potentials. In this study, B. subtilis BSC35 was newly-isolated and its BLIS-containing cell-free supernatant exhibited...
Thu, 11/26/2020 - 06:11
LWT
Author(s): Yifang Cao, Donggen Zhou, Xiaowei Zhang, Xinglong Xiao, Yigang Yu, Xiaofeng Li The combined effects of four substances, carvacrol, citral, thymol and caprylic acid, on the growth of Cronobacter sakazakii CICC 21544 were evaluated. Among the six combinations, only the combination of citral and carvacrol demonstrated a synergistic effect. This combination had a stronger growth inhibition...
Thu, 11/26/2020 - 06:11
LWT
Author(s): S. Anjana, Abhilash Sasidharan, B. Varghese, Sarasan Sabu, K.V. Sunooj, K.A.Martin Xavier A cost-effective, portable, ultra violet assisted vertical re-circulatory depuration system (UVDC) was developed and its effect on microbiological, heavy metal and proximate composition of Black clam (Villorita cyprinoides) was investigated. The process of depuration was found to be effective in...
Thu, 11/26/2020 - 04:01
Staphylococcus aureus is a primary pathogen responsible for causing postoperative infections as it survives and persists in host cells, including osteoblasts and macrophages. These cells then serve as reservoirs resulting in chronic infections. Most traditional antibiotics have poor effects on intracellular S. aureus because they cannot enter the cell. Herein, a cell-penetrating peptide TAT-KR-12...
Thu, 11/26/2020 - 00:00
As the field of forensic DNA analysis has started to transition from genetics to genomics, new methods to aid in crime scene investigations have arisen. The development of informative single nucleotide polymorphism (SNP) markers has led the forensic community to question if DNA can be a reliable “eye-witness” and whether the data it provides can shed light on unknown...
Thu, 11/26/2020 - 00:00
Agricultural fungicides contaminate the environment and promote the spread of fungicide-resistant strains of pathogenic fungi. The enhancement of pathogen sensitivity to these pesticides using chemosensitizers allows the reducing of fungicide dosages without a decrease in their efficiency. Using Petri plate and microplate bioassays, 6-demethylmevinolin (6-DMM), a putative sensitizer of a...
Wed, 11/25/2020 - 16:00
Cryptosporidium and Giardia are two important zoonotic intestinal protozoa responsible for diarrheal diseases in humans and animals worldwide. Feces from infected hosts, water and food contaminated by Cryptosporidium oocysts and Giardia cysts as well as predictors such as poverty have been involved in their transmission. Myanmar is one of the world’s most impoverished countries. To date, there...
Wed, 11/25/2020 - 16:00
Toxoplasmosis is a parasitic disease affecting human, livestock and cat. Prophylactic strategies would be ideal to prevent infection. In a One Health vaccination approach, the objectives would be the prevention of congenital disease in both women and livestock, prevention/reduction of T. gondii tissue cysts in food-producing animals; and oocyst shedding in cats. Over the last few years, an...
Wed, 11/25/2020 - 14:03
Helium is commonly used as a carrier gas in gas chromatography-tandem mass spectrometry (GC-MS/MS); however, there are growing concerns regarding its global shortage and the resulting limited supply and high cost. Using nitrogen as an alternative carrier gas in GC-MS/MS with the widely used electron ionisation (EI) technique leads to a significantly lower sensitivity; thus, in this study, we...
Wed, 11/25/2020 - 12:01
Background We investigated whether the incidence of death following myocardial infarction (MI) varied by season and latitude in the Swedish population. Methods We studied deaths following MI from January 1987 to December 2009, using the Swedish National Cause of Death Register. County of residence was used to determine latitude and population density. An extension of Poisson regression was used...

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