Research Publications from Peer-Reviewed Journals

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Tue, 07/07/2020 - 22:09
Phage therapy is considered an alternative modality in the treatment of different bacterial diseases. However, their therapeutic and preventive roles against infections caused by S.Kentucky and E.coli O119 were of little attention. In this study, two phages were isolated, characterized, and assessed for their potential therapeutic and preventive roles against S.Kentucky and E.coli O119 infections...
Tue, 07/07/2020 - 22:08
Piscine orthoreovirus infects various salmonid fish species, and the infection is associated with diseases such as heart and skeletal muscle inflammation (HSMI) in farmed Atlantic salmon (Salmo salar). There are no vaccines available or genetically selected resistant hosts that can efficiently control piscine orthoreovirus (PRV) infection. Currently, the only prophylactic measure against PRV is...
Tue, 07/07/2020 - 22:07
This study aimed to evaluate the influence of plasma treatment time, bacterial exposure time to PAW, and bacterial species on the inactivation efficacy of plasma‐activated water (PAW), with additional investigation of the inactivation mechanisms of PAW. Six bacterial species, including Listeria innocua, Staphyloccus aureus, Escherichia coli, Pseudomonas fluorescens, Shewanella putrefaciens, and...
Tue, 07/07/2020 - 22:06
BACKGROUND Fish consumption is increasing nowadays both because of its positive role for health due to the abundant presence of unsaturated fatty acids and for its use in many new food preparations (e.g. raw fillet used for uncooked sushi and sashimi dishes). The growing food industry and increased demand for the long‐term storage and preservation of food have created the need to develop methods...
Tue, 07/07/2020 - 18:01
The factor VIII (FVIII)-neutralizing antibody (inhibitor) seen in 25%–30% of patients with severe haemophilia A (SHA). Vaccination is a non-genetic risk factor of inhibitor development as ‘danger signal’ which may provide a pro-inflammatory microenvironment to increase FVIII immunogenicity. We reported a previously treated SHA patient postponed the first vaccination to 15-month age received...
Tue, 07/07/2020 - 16:00
Excessive cadmium (Cd) damages plants by causing cell death. The present study discusses the function of natural resistance-associated macrophage protein (NRAMP) on cell death caused by Cd in Malus hupehensis. MhNRAMP1 was isolated from M. hupehensis roots, and its protein was located in the cell membrane as a transmembrane protein characterized by hydrophobicity. MhNRAMP1 expression in the roots...
Tue, 07/07/2020 - 16:00
Trace metal contaminations in natural waters, wetlands, and wastewaters pose serious threats to aquatic ecosystems—mainly via targeting microalgae. In this work, we investigated the effects of toxic amounts of chromium and cadmium ions on the structure and function of the photosynthetic machinery of Chlorella variabilis cells. To halt the propagation of cells, we used high concentrations of Cd...
Tue, 07/07/2020 - 16:00
Sensing and responding to environmental cues is critical for the adaptability and success of the food-borne bacterial pathogen Listeria monocytogenes. A supramolecular multi-protein complex known as the stressosome, which acts as a stress sensing hub, is responsible for orchestrating the activation of a signal transduction pathway resulting in the activation of σB, the sigma factor that controls...
Tue, 07/07/2020 - 16:00
Salmonellosis is a foodborne disease caused by Salmonella spp. Although cell culture is the gold standard for its identification, validated molecular methods are becoming an alternative, because of their rapidity, selectivity, and specificity. A simplex and duplex droplet digital polymerase chain reaction (ddPCR)-based method for the identification and quantification of Salmonella using ttr, invA...
Tue, 07/07/2020 - 16:00
Previous studies have identified oral administration of antibiotics and gut-impacting drugs as critical drivers for fecal antibiotic resistance (AR) and microbiome disruption in lab mice, but the practical implications of these findings have yet to be validated in hosts nurtured in conventional environment. Using ampicillin (Amp) as a way to extrapolate the general effect of antibiotics, this...
Tue, 07/07/2020 - 16:00
During the development of antimicrobial peptides (AMP) as potential therapeutics, antimicrobial susceptibility testing (AST) stands as an essential part of the process in identification and optimisation of candidate AMP. Standard methods for AST, developed almost 60 years ago for testing conventional antibiotics, are not necessarily fit for purpose when it comes to determining the susceptibility...
Tue, 07/07/2020 - 10:01
Both fermentative and respiratory processes contribute to bacterial metabolic adaptations to low oxygen tension (hypoxia). In the absence of O2 as a respiratory electron sink, many bacteria utilize alternative electron acceptors such as nitrate (NO3-). During canonical NO3- respiration, NO3- is reduced in a stepwise manner to N2 by a dedicated set of reductases. Vibrio cholerae, the etiological...
Tue, 07/07/2020 - 10:01
Clostridioides difficile is an aetiological agent for antibiotic-associated diarrhoeal disease. C. difficile produces a phenolic compound, para-cresol, which selectively targets gammaproteobacteria in the gut, facilitating dysbiosis. C. difficile decarboxylates para-hydroxyphenylacetate (p-HPA) to produce p-cresol by the action of the HpdBCA decarboxylase encoded by the hpdBCA operon. Herein, we...
Tue, 07/07/2020 - 08:01
by Sarah K. Wilson, Justine Heckendorn, Bruno Martorelli Di Genova, Lindsey L. Koch, Peggy J. Rooney, Naomi Morrissette, Maryse Lebrun, Laura J. Knoll Toxoplasma gondii is an obligate intracellular parasite that can invade any nucleated cell of any warm-blooded animal. In a previous screen to identify virulence determinants, disruption of gene TgME49_305140 generated a T. gondii mutant that could...
Tue, 07/07/2020 - 08:01
by Minglu Gao, Anthony E. Glenn, Xi Gu, Trevor R. Mitchell, Timothy Satterlee, Mary V. Duke, Brian E. Scheffler, Scott E. Gold Sarocladium zeae is a fungal endophyte of maize and can be found co-inhabiting a single seed with Fusarium verticillioides, a major mycotoxigenic food safety threat. S. zeae produces pyrrocidines A and B that inhibit the growth of F. verticillioides and may limit its...
Tue, 07/07/2020 - 06:09
Author(s): Katarina Baralić, Katarina Živančević, Dragana Javorac, Aleksandra Buha Djordjevic, Milena Anđelković, Dragica Jorgovanović, Evica Antonijević Miljaković, Marijana Ćurčić, Zorica Bulat, Biljana Antonijević, Danijela Đukić-Ćosić Phthalates and bisphenol A, to which people are mainly exposed through food, interfere with the body's endocrine system, along with various other toxic effects...
Tue, 07/07/2020 - 02:02
Abstract Pullulanases are widely used in food, medicine, and other industries because they specifically hydrolyze α-1,6-glycosidic linkages in starch and oligosaccharides. In addition, high-temperature thermostable pullulanase has multiple advantages, including decreasing saccharification solution viscosity accompanied with enhanced mass transfer and reducing microbial contamination in starch...
Tue, 07/07/2020 - 02:01
In order to assess environmental exposure-associated human health risk of dioxin compounds for the population in the vicinity of a municipal solid waste incinerator (MSWI) in Shanghai, the atmospheric samples (n = 24) and soils samples (n = 96) were collected and analyzed to obtain the concentration level, pollution characteristics and seasonal changes of dioxin compounds in environmental medias...
Tue, 07/07/2020 - 02:01
The COVID-19 crisis has exposed the vulnerability of India’s Agri food system and accentuated the need for agricultural market reforms and digital solutions to connect farmers to markets, to create safety nets and ensure reasonable working conditions, and to decentralize Agri food systems to make them more resilient.
Tue, 07/07/2020 - 02:01
To investigate the potential pollution risk of permeable brick paving systems in areas with high groundwater levels, a system was constructed by using ceramic permeable bricks as the surface and a Chinese character “well”-shaped frame as the base on the top of a 1.0 m clay layer. The concentrations of total suspended solids (TSS), total phosphorus (TP), ammonia nitrogen (NH4+-N), total nitrogen (...
Tue, 07/07/2020 - 00:00
Life expectancy has gradually grown over the last century. This has deeply affected healthcare costs, since the growth of an aging population is correlated to the increasing burden of chronic diseases. This represents the interesting challenge of how to manage patients with chronic diseases in order to improve health care budgets. Effective primary prevention could represent a promising route. To...
Tue, 07/07/2020 - 00:00
Botulinum toxin type A (BTXA) has been used for over 25 years in the management of pediatric lower and upper limb hypertonia, with the first reports in 1993. The most common indication is the injection of the triceps surae muscle for the correction of spastic equinus gait in children with cerebral palsy. The upper limb injection goals include improvements in function, better positioning of the...
Tue, 07/07/2020 - 00:00
The main objective of this study was to develop a simple and efficient spectrophotometric technique combined with chemometrics for the simultaneous determination of sulfamethoxazole (SMX) and trimethoprim (TMP) in drug formulations. Specifically, we sought: (i) to evaluate the potential use of rank annihilation factor analysis (RAFA) to pH gradual change spectrophotometric data in order to...
Mon, 07/06/2020 - 22:12
In this review, we highlight new and emerging metrics and tools in esophageal function testing and the clinical manifestations and management of esophageal involvement in connective tissue disorders. Abstract This work summarizes new and emerging metrics and tools in esophageal function testing and their potential clinical impact. Because the diagnostic sensitivity and reliability of conventional...
Mon, 07/06/2020 - 22:10
High levels of p‐Coumaric acid was first isolated and identified from Spirulina. Inhibitory kinetics and mechanism of p‐Coumaric acid on two enzymes were studied. Molecular modeling revealed the Spirulina p‐Coumaric acid binding mode. Abstract Spirulina species are edible with high nutritional as well as potential therapeutic values. In this work, we show that phenolic extracts from Spirulina (p‐...
Mon, 07/06/2020 - 22:10
This research is an application of fiber‐in‐tube solid phase microextraction followed by HPLC‐UV for extraction and determination of trace amounts of bisphenol A. Nano magnetic Fe3O4 was formed on the surface of polypropylene porous hollow fibers to increase the surface area and then it was coated with polystyrene. The introduction of polystyrene improves the surface hydrophobicity and is an...
Mon, 07/06/2020 - 22:10
CE is a modern separation technique characterized by many benefits, which qualify it also for enzyme assays and the study of enzyme kinetics during drug development. Homogenous or heterogenous approaches can be followed for the enzymatic incubation. In this study, an immobilization procedure of aldehyde oxidase on magnetic particles was developed considering their integration with CE. A number of...
Mon, 07/06/2020 - 22:07
Di‐n‐butyl phthalate (DBP) is known to have adverse effects on reproduction in mammals and is pervasive in the aquatic environment. The objective of the present study was to investigate whether long‐term exposure to low concentrations of DBP can affect fish reproduction. In this study, zebrafish (Danio rerio) embryos (F0) were exposed to low concentrations (4.9, 13.6 and 43.8 μg/L) of DBP from 2...
Mon, 07/06/2020 - 14:04
A study of pesticide residues was investigated in vegetable samples to highlight the trend of drugs obtained from the Jilin Province, China. Total of 230 samples obtained from four regions over the period 2016–2017 were screened for 18 pesticides that were analyzed using gas chromatography with electron capture (GC-ECD). The results showed that 45 samples (19.6%) were positive including 17...
Mon, 07/06/2020 - 06:09
Author(s): Qianchun Zhang, Yanqun Yang, Changbo Zhang, Yuguo Zheng, Yun Wun, Xingyi Wang Patulin is a type of mycotoxin that can compromise both food quality and human health, and its potential toxic effects on human health are concerning. Therefore, strict monitoring of patulin content in food systems is necessary. However, discrimination and quantification of this toxin are difficult because of...
Mon, 07/06/2020 - 06:08
Author(s): Ellen Mendez, Diane K. Walker, Jessie Vipham, Valentina Trinetta Listeria monocytogenes is one of the most concerning pathogens for the food industry due to its ability to form biofilms, particularly in difficult-to-clean sites of processing facilities. There is a current industry-wide lack of data to refer to when selecting a strategy to control L. monocytogenes biofilms in the food...
Mon, 07/06/2020 - 06:08
Author(s): M.F. Peruzy, M. Aponte, Y.T.R. Proroga, F. Capuano, D. Cristiano, E. Delibato, K. Houf, N. Murru Conventional methods for Yersinia enterocolitica detection in food samples are generally considered inadequate. Problems arise from the presence of the so-called “background flora”, coupled to the low contamination level of the pathogen. Since, data on the microbial ecology occurring in...
Mon, 07/06/2020 - 04:03
Acetylcholinesterase inactivating compounds, such as organophosphate (OP) and carbamate (CM) pesticides, are widely used in agriculture to ensure sustainable production of food and feed. As a consequence of their applications, they would result in neurotoxicity, even death. In this essence, the development of enzyme inhibition methods still shows great significance as rapid detection techniques...
Mon, 07/06/2020 - 00:01
It is widely known that pneumonia (either community acquired or hospital acquired, as like ventilator associated pneumonia (VAP)), is the most frequent type of severe infection and continues to pose a significant burden on healthcare services worldwide. Despite new diagnostic developments, most pneumonia cases continue to be difficult to diagnose clinically, partly due to acquired antibiotic...
Sun, 07/05/2020 - 22:07
The effects of ultraviolet (UV)‐C irradiation on the physicochemical properties of oyster mushroom polysaccharide (OMP) films were investigated. The prepared OMP films were subjected to UV‐C treatment (5.4 kJ/m2). UV‐C irradiation increased the tensile strength and decreased the water vapour permeability of the OMP films. In addition, the incorporation of 1.0% Cudrania tricuspidata leaf extract (...
Sun, 07/05/2020 - 08:02
Edible films can be designed to serve as carriers of antimicrobial agents and be used to control pathogenic foodborne viruses and bacteria. This research tested this concept by dissolving green tea extract (GTE) in chitosan film-forming solutions (FFS) and using it to prepare dried chitosan edible films. As a control, the GTE was also dissolved in deionized water (DW). The FFS and the dried...
Sun, 07/05/2020 - 06:09
Author(s): Angela Maria García-Sánchez, Marta Reguera-Gomez, Maria Adela Valero, Cristina Cutillas Human trichuriasis is a neglected tropical disease which affects millions of people worldwide, mostly living in low socio-economic conditions. Numerous studies have been conducted over the past 10 years to compare the different techniques for T. trichiura eggs detection. Our study provides the first...
Sun, 07/05/2020 - 06:09
Author(s): Fangfang Yan, Li Zhao, Wanbing Chen, Qun Lu, Cuie Tang, Chengming Wang, Rui Liu This study evaluated the stabilities of catechin (C), epicatechin (EC), procyanidin B3, procyanidin A1 and epicatechin-(4β → 6)-epicatechin-(2β → O → 7,4β → 8)-catechin (PCA-trimer) during in vitro digestion, as well as characterized their digestion products (DPs), and evaluated their protective effects...
Sun, 07/05/2020 - 06:08
Author(s): Ling Jin, Ting Li, Tan Yang, Xuehua Liang, Bin Wu, Dengchao Zou, Liwen Hu, Ganhui Huang, Jinsheng Zhang The monitoring and control of foodborne pathogenic microorganisms to protect food safety is of great significance. A biosensor based on superparamagnetic ultra-small iron oxide nanoparticles (USIO NPs) combined with membrane filtration and low field nuclear magnetic resonance (LF-NMR...
Sun, 07/05/2020 - 06:08
Author(s): Madeleine Moazzami, Lise-Lotte Fernström, Ingrid Hansson It is critical to maintain low levels of microbes in the whole food production chain. Due to high speed of slaughter, lack of time, and structural characteristics of crates, sufficient cleaning and disinfection of crates used for transporting chickens to abattoirs is a challenge. Inadequately cleaned transport crates for broiler...
Sun, 07/05/2020 - 06:08
Author(s): Florence Becot, Jason Parker, David Conner, Lori Pivarnik, Nicole Richard, Diane Wright-Hirsch The 2011 Food Safety Modernization Act (FSMA) exempts most small- and medium-scale growers in the U.S. from the new produce safety rule that creates a set of minimum safety standards for producing and processing fresh fruits and vegetables. While the exemption may limit the financial burden...
Sun, 07/05/2020 - 06:08
Author(s): Janne Lundén, Mikko Kosola, Juho Kiuru, Jenni Kaskela, Tommi Inkinen The consistency of inspections is an important requirement of official food control. Inconsistency may endanger food safety and lead to mistrust in official food control. The reasons leading to inconsistency and the mitigation of inconsistency are therefore important. Here we investigated the distribution of...
Sun, 07/05/2020 - 06:07
Author(s): Wei Quan, Yong Li, Ye Jiao, Chaoyi Xue, Guoping Liu, Zhaojun Wang, Zhiyong He, Fang Qin, Maomao Zeng, Jie Chen The simultaneous formation of acrylamide; β-carboline heterocyclic amines (HAs): harmane and norharmane; and advanced glycation end products (AGEs) (Nε-(carboxymethyl)lysine (CML) and Nε-(carboxyethyl)lysine (CEL)) was analyzed based on an aqueous model system. The model...
Sun, 07/05/2020 - 06:06
Author(s): Andrew D. Younger, Anna Neish, David I. Walker, Kaitlyn L. Jenkins, James A. Lowther, Tina A. Stapleton, Mickael Teixeira Alves Depuration of oysters can effectively reduce levels of E. coli, however, may not be effective in safeguarding against viral contamination (EFSA, 2012). These trials assess the removal of Norovirus Genogroups I and II (NoV GI and GII) and F + RNA bacteriophage...
Sun, 07/05/2020 - 06:06
Author(s): Huihui Zhang, Zisong Xu, Kaiwen Guo, Yuze Huo, Guoqiang He, Hongwei Sun, Yupeng Guan, Nan Xu, Wei Yang, Guangyu Sun To explore the mechanisms underlying the action of the heavy metals Cd and Zn on the photosynthetic function of plant leaves, the effects of 100 μmol L−1 Cd and 200 μmol L−1 Zn stress (the exposure concentrations of Cd and Zn in the culture medium were 2.24 mg kg−1 and 5....
Sun, 07/05/2020 - 06:06
Author(s): Wantang Huang, Hua Yin, Yuanyuan Yu, Guining Lu, Zhi Dang, Zhanghong Chen In this study, Pseudomonas aeruginosa was applied to degrade tetrabromobisphenol A (TBBPA) with glucose as a co-metabolic substrate. Influencing factors of co-metabolic degradation such as pH, TBBPA and glucose concentration were examined and the degradation efficiency under optimal condition reached about 50% on...
Sun, 07/05/2020 - 06:06
Author(s): Jianbo Shi, Yong Cai Heavy metals have been extensively used in industry, agriculture, medicine and other fields for a long history. Their wide distribution in the environment raised great concern for adverse effects on environment and human health. Although studies have been conducted for many years, key processes and mechanisms regarding environmental chemistry and ecotoxicology of...
Sun, 07/05/2020 - 02:01
Vibrio parahaemolyticus (V. parahaemolyticus) is one of the most common and widely distributed food-borne bacteria. Thus, it is necessary to establish a rapid, specific, and sensitive detection approach for V. parahaemolyticus. The strategy of combining immunomagnetic separation method (IMS) and polymerase chain reaction (PCR) measure was established successfully for V. parahaemolyticus detection...
Sun, 07/05/2020 - 00:00
Overwhelming empirical evidence has highlighted the contribution of indiscriminate antibiotic usage (ABU) in food animals to the overall burden of antibiotic resistance (ABR) in humans, thus making antibiotic use the main selective pressure driving antibiotic resistance. The social and behavioral perspective on antibiotic use and resistance in poultry is limited. Our study therefore aimed at...
Sat, 07/04/2020 - 06:11
Author(s): Dilumi W.K. Liyanage, Dmytro P. Yevtushenko, Michele Konschuh, Benoît Bizimungu, Zhen-Xiang Lu Potato chips are among the highest contributors to the dietary intake of acrylamide, a potent neurotoxin and likely carcinogen in heat-processed foods. The present study aimed to determine the effects of frying conditions and additive treatments on reducing sugars, asparagine levels, and...

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