Research Publications (Food Safety)

Salmonella , a major foodborne pathogen, causes severe gastrointestinal disease in people and animals worldwide. Plasmid-borne mcr-1 , which confers colistin resistance in Salmonella, has significant epidemiological interest for public health safety.

As incidence of foodborne infection is more prevalent among cancer patients, and the domestic kitchen reported to be a contributor to foodborne infection; there is a need to ensure appropriate domestic food safety practices to safeguard this ‘at-risk’ population.

Production of value-added foods is of growing interest to small-scale produce growers. However, previous studies reported that they lack sufficient food safety awareness and have limited knowledge of applicable food safety regulations. Targeted food safety education can help to address these challenges.

  Salmonella enterica   serovar Infantis is the fifth most common   Salmonella   serovar isolated in England and Wales.

Patulin, a mycotoxin, is known to have cytotoxic effects, but few studies have focused on the involvement of the endoplasmic reticulum (ER) stress response in patulin toxicity and the natural compounds that attenuate it in HepG2 cells. This study tested the ability of patulin to induce ER stress, and that of four thiols and three thioethers to attenuate patulin-induced ER stress in HepG2 cells. Patulin dose-dependently inhibited cell proliferation (IC50, 8.43 μM).

Mycotoxins in small grains are a significant and long-standing problem. These contaminants may be produced by members of several fungal genera, including Alternaria, Aspergillus, Fusarium, Claviceps, and Penicillium. Interventions that limit contamination can be made both pre-harvest and post-harvest.

Lead is an occupational toxicant and a recognised health threat particularly in developing countries. Hence, this study explored the interaction of blood lead level (BLL), a conventional marker of lead exposure, with indices of calcium metabolism and biomarkers of bone-turnover in 120 adult male automobile technicians (AT) with ≥ 1 year duration in professional practice.

In this study, the diversity of bphA genes was assessed in a 13C-enriched metagenome upon stable isotope probing (SIP) of microbial populations in legacy PCB-contaminated soil with 13C-biphenyl (BP). In total, 13 bphA sequence variants (SVs) were identified in the final amplicon dataset.

Carbapenem-resistant Enterobacterales (CRE) are pathogens that have been found in several countries, with a significant public health concern. Characterizing the mode of resistance and determining the prevailing clones are vital to the epidemiology of CRE in our community. This study was conducted to characterize the molecular mode of resistance and to determine the clonality of the CRE fecal isolates among community food handlers (FHs) vs. infected control patients (ICPs) in Kuwait.

Background:Campylobacter is commonly transmitted to humans from chickens. Campylobacter jejuni is the species most frequently associated with human illness, and the most prevalent species recovered from poultry.

Sepsis is a common and often treacherous medical emergency with a high mortality and long-term complications in survivors. Though antibiotic therapy can reduce death rate of sepsis significantly, it impairs gut microbiota (GM), which play imperative roles in human health.

Great progress has been made in the prevention and treatment of human parasitic diseases in China over the past six decades, but parasitic diseases are still one of the most serious public health problems in the world. The specific prevalence of parasitic diseases varies in different provinces due to their geographical environment and the dietary habits of people.

Background

Group B Streptococcus (GBS, S. agalactiae) is a human commensal and occasional pathogen that remains a leading cause of neonatal sepsis and meningitis with increasing disease burden in adult populations. Although programs for universal screening in pregnancy to guide intrapartum prophylaxis have reduced GBS invasive disease burden resulting from mother-to-newborn transfer during birth, better knowledge of disease mechanisms may elucidate new strategies to reduce antibiotic exposure.

Flunixin is a nonsteroidal anti-inflammatory drug approved for use in cattle to manage pyrexia associated with bovine respiratory disease, mastitis, and endotoxemia. In the United States, no nonsteroidal anti-inflammatory drugs are approved for use in goats, but analgesics are needed for management of painful conditions to improve animal welfare.

Recycled manure solids (RMS) bedding is an alternative bedding option that is growing in popularity on Canadian dairy farms. However, the microbiological characteristics and production of RMS bedding are poorly documented under on-farm conditions in eastern Canada. This bedding could support the presence of pathogens and could have an effect on cow and human health. The aim of this study was to describe the RMS microbiota when used under dairy cows and compare it with straw bedding.

Author(s): Min Li, Yidi Kong, Xueqin Wu, Zhuang Yin, Xiaotian Niu, Guiqin Wang

Author(s): Libing Chu, Jianlong Wang, Chuanhong Chen, Yunpeng Shen, Shijun He, László Wojnárovits, Erzsébet Takács, Youxue Zhang

Author(s): Sarah Azinheiro, Dipak Ghimire, Joana Carvalho, Marta Prado, Alejandro Garrido-Maestu

Author(s): Mi Wu, Lu Tian, Jiapeng Fu, Sichen Liao, Hui Li, Zhongchao Gai, Guoli Gong

Author(s): Alexandra Belias, Genevieve Sullivan, Martin Wiedmann, Renata Ivanek

Author(s): Hua Ping, Beihong Wang, Cheng Li, Yang Li, Xuejiao Ha, Wenshen Jia, Bingru Li, Zhihong Ma

Author(s): Lina Sheng, Xiaoye Shen, Yuan Su, Yansong Xue, Hui Gao, Manoella Mendoza, Tonia Green, Ines Hanrahan, Mei-Jun Zhu

Author(s): Mariem Rouatbi, Safa Amairia, Said Samed, Mourad Rekik, Mohamed Aziz Darghouth, Afef Jeljli, Mohamed Gharbi

Author(s): Luciane A. Chimetto Tonon, Cintia Rua, Camila M. Crnkovic, Darlon I. Bernardi, Osmindo R. Pires Junior, Célio F.B. Haddad, Carolina da S. G. Pedrosa, Leticia R.Q. Souza, Stevens K. Rehen, Gustavo P.R. de Azevedo, Cristiane C. Thompson, Fabiano L. Thompson, Roberto G.S. Berlinck