Research Publications from Peer-Reviewed Journals

Wed, 11/27/2019 - 03:26
ABSTRACT Interactions between the gut microbiome and immunoglobulin A (IgA) in the gut during infancy are important for future health. IgM and IgG are also present in the gut; however, their interactions with the microbiome in the developing infant remain to be characterized. Using stool samples sampled 15 times in infancy from 32 healthy subjects at 4 locations in 3 countries, we characterized...
Wed, 11/27/2019 - 03:26
ABSTRACT The 7th cholera pandemic began in 1961 in Sulawesi, Indonesia, and then spread around the world in at least three waves. However, the lack of genome sequences for Vibrio cholerae strains under long-term surveillance in East Asia, especially in China, has restricted our understanding of the dynamics of the intracountry and intercountry evolution and transmission of the 7th-pandemic clones...
Wed, 11/27/2019 - 03:24
Author(s): Shunchun Yao, Lifeng Zhang, Yeming Zhu, Junye Wu, Zhimin Lu, Jidong LuAbstractHeavy metal elements are the main pollutants in municipal solid waste incineration (MSWI) fly ash, the online detection of heavy metals in MSWI fly ash could benefit its subsequent solidification treatment and land-filling. In this paper, laser induced breakdown spectroscopy (LIBS) was introduced to the rapid...
Wed, 11/27/2019 - 03:24
Author(s): Lorenzo Mazza, Xiaopeng Xiao, Kashif ur Rehman, Minmin Cai, Dingnan Zhang, Salvatore Fasulo, Jeffery K. Tomberlin, Longyu Zheng, Abdul Aziz Soomro, Ziniu Yu, Jibin ZhangAbstractBlack soldier fly (BSF) is used for the management of organic waste, but research has hardly explored the effect of companion bacteria when chicken manure (CHM) is converted to insect biomass. In this study, we...
Wed, 11/27/2019 - 03:24
Author(s): Elisabet Marti, Meritxell Gros, Mercè Boy-Roura, Jonatan Ovejero, Anna M. Busquets, Joan Colón, Mira Petrovic, Sergio PonsáAbstractThe fate and degradation of 28 multiple-class veterinary pharmaceuticals in an on-farm pig slurry treatment plant based on solid-liquid separation and a nitrification–denitrification (NDN) sequence batch reactor (SBR) were evaluated for the first time. The...
Wed, 11/27/2019 - 03:24
Author(s): Na Wang, Kezhen Qian, Dezhen Chen, Hengzhen Zhao, Lijie YinAbstractThe gas and oil product derived from municipal solid waste (MSW) pyrolysis was upgraded by utilizing the interaction between the volatile compounds and the char and the mechanism involved is explored. The influences of operation parameters, including interaction temperature, char/volatiles mass ratio (C/V) and gas...
Wed, 11/27/2019 - 03:24
Author(s): Carla S. Fermanelli, Agostina Córdoba, Liliana B. Pierella, Clara SauxAbstractIn this study, pyrolysis of residual biomass from the agro-alimentary industry of Argentina was investigated. The studied biomasses were rice husk, peanut shell and wheat straw. The effect of pyrolysis temperature over solid (bio-char), liquid (bio-oil) and gas (bio-gas) fractions weight yields were evaluated...
Wed, 11/27/2019 - 03:24
Author(s): Mingfei Xing, Yu Li, Lei Zhao, Xiaoyan Song, Zegang Fu, Yajie Du, Xingyu HuangAbstractWaste printed circuit boards (WPCBs) contain a large amount of brominated epoxy resins (BERs), which may cause environmental problems. However, BERs degradation under mild conditions is challenging due to the good thermal and chemical stabilities of BERs. This study proposes a mild and efficient...
Wed, 11/27/2019 - 03:23
Author(s): Elisa Gayán, Elise Geens, Daniel Berdejo, Diego García-Gonzalo, Rafael Pagán, Abram Aertsen, Chris W. MichielsAbstractThe growing demand for minimally processed foods with clean labels has stimulated research into mild processing methods and natural antimicrobials to replace intensive heating and conventional preservatives, respectively. However, we have previously demonstrated that...
Wed, 11/27/2019 - 03:23
Author(s): Mathieu Gand, Wesley Mattheus, Nancy H.C. Roosens, Katelijne Dierick, Kathleen Marchal, Sigrid C.J. De Keersmaecker, Sophie BertrandAbstractSalmonella is a major pathogen having a public health and economic impact in both humans and animals. Six serotypes of the Salmonella genus are mentioned in the Belgian and European regulation as to be rapidly excluded from the food chain (EU...
Wed, 11/27/2019 - 03:22
Author(s): Carlos Flores-Ortiz, Lilia M. Alvarez, Alejandro Undurraga, Daniela Arias, Felipe Durán, Guillermo Wegener, Claudia StangeAbstractDaucus carota is a biennale crop that develops an edible storage root. Orange carrots, the most consumed cultivar worldwide, accumulate high levels of β-carotene and α-carotene in the storage root during secondary growth. Genes involved in β-carotene...
Wed, 11/27/2019 - 03:22
Author(s): Priyanka Mahadappa, Narayanan Krishnaswamy, Mahendran Karunanidhi, AG Bhanuprakash, BV Bindhuja, Sahadeb DeyAbstractRumen impaction by plastic waste (PW) is a common condition in the developing countries where ruminants are reared under extensive grazing. As heavy metals (HM) are used in the manufacture of plastic, we hypothesized that buffaloes with PW impaction would have suboptimal...
Wed, 11/27/2019 - 03:21
Author(s): Xiaodan Li, Cyrill Brunner, Yufan Wu, Oneda Leka, Gisbert Schneider, Richard A. KammererABSTRACTA dual-receptor interaction with a polysialoganglioside and synaptic vesicle glycoprotein 2 (SV2) is required for botulinum neurotoxin A (BoNT) toxicity. Here, we review what is currently known about the BoNT/A-SV2 interaction based on structural studies. Currently, five crystal structures...
Wed, 11/27/2019 - 03:21
Author(s): Shiro Itoi, Sora Tabuchi, Misato Abe, Hiroyuki Ueda, Hikaru Oyama, Ryuya Ogata, Taiki Okabe, Ayano Kishiki, Haruo SugitaAbstractPlanocerid flatworms and the related species (Platyhelminthes: polycladida) are known as tetrodotoxin (TTX)-bearing organisms, and they contribute to toxification of marine organisms at higher trophic levels, such as pufferfish and sea slugs. However, little...
Wed, 11/27/2019 - 03:21
Author(s): Naeem Sheik Abdul, Savania Nagiah, Krisnan Anand, Anil A. ChuturgoonAbstractFusaric acid (FA) is a ubiquitous yet neglected mycotoxin. The toxicity of FA is associated with mitochondrial dysfunction and oxidative stress. Sirtuins (SIRTs) are key mediators of cell stress responses through deacetylation of antioxidant, mitochondrial maintenance and energy metabolism proteins. Dietary...
Wed, 11/27/2019 - 03:20
Aflatoxin M1 (AFM1) contamination in 150 samples of milk, sold in market of Hisar city of Haryana, India, was investigated by using High Pressure Liquid Chromatography (HPLC). Out of these, 40 samples contained AFM1 at a concentration below the limit of detection (LOD) of 0.052 μg/kg. Among the AFM1 contaminated samples, 46 raw milk samples contained a concentration above the LOD but less than...
Wed, 11/27/2019 - 03:19
Concern about the safety of acrylamide in french fries led to the identification of potato varieties low in the acrylamide precursors asparagine and reducing sugars that vary with variety, nitrogen (N) fertilizer applications, and other factors, but produce light‐colored fries, which may not appeal to consumers. New potato varieties shown to produce low‐acrylamide fries, AF4296‐3 and Easton, and...
Wed, 11/27/2019 - 03:19
Methicillin‐resistant Staphylococcus aureus (MRSA), a versatile pathogen bearing multiple virulence determinants, is increasingly being detected in various food‐producing animals, including fish. In addition, it is a potential food poisoning agent. MRSA is not an inherent microbiota of fish; its presence is attributed to pre‐ or postharvest contamination through fish handlers, water, ice, and...
Wed, 11/27/2019 - 03:19
Mycotoxins presence was evaluated in animal feed marketed in Tunisia for the first time ever. A QuEChERS method was performed to analyze the natural copresence of 22 mycotoxins (enniatins, beauvericin, ochratoxin A, aflatoxins, alternariol monomethyl ether, alternariol, tentoxin, zearalenone, deoxynivalenol, 3‐acetyldeoxynivalenol, 15‐acetyldeoxynivalenol, nivalenol, neosolaniol,...
Wed, 11/27/2019 - 03:18
This article review the emerging trends in the spread, distribution, and epidemiology of Listeria species in foods, water, human, animals, and different environments in the Southern African sub‐region based on the appraisal of scholarly articles available online. Reports obtained from literatures revealed that traditional microbiological method and the principle of aesculin hydrolysis on...
Wed, 11/27/2019 - 03:18
Dendrogram analysis of ERIC& REP fingerprints of ESBL producing Klebsiella pneumoniae isolates. Abstract Klebsiella species have been at the center of attention over the recent years due to its role in the evolution of antimicrobial resistance and is not only associated with nosocomial but also with food related infections worldwide. In this study, out of 336 samples of animal intestinal and...
Wed, 11/27/2019 - 03:18
Spot map showing areas of sample collection from Delhi‐NCR. Abstract Fresh fruits and vegetables contaminated with microbial pathogens can cause outbreaks of food poisoning and other enteric diseases if consumed raw. The objective of the present study was to determine the bacterial contamination and antibiotic resistance in fresh produce sold in Delhi, India. One hundred fifty samples of fruits...
Wed, 11/27/2019 - 03:18
This report presents the first ultra‐high performance supercritical fluid chromatography diode array detector based assay for simultaneous determination of iridoid glucosides, flavonoid glucuronides, and phenylpropanoid glycosides in Verbena officinalis (Verbenaceae) extracts. Separation of the key metabolites was achieved in less than 7 min on an Acquity UPC2 Torus Diol column using a mobile...
Wed, 11/27/2019 - 03:16
BACKGROUND Heavy metal resistant bacterium Enterobacter sp. C1D was evaluated for cadmium (Cd) mediated exopolysaccharide production, biofilm formation and legume root colonization ability under Cd stress to alleviate metal induced stress. RESULTS The plant was sensitive to Cd (IC50 3‐ 4μg/ml), while the bacterium showed high Cd tolerance (MIC99 120 μg/ml). Confocal laser scanning microscopy of...
Wed, 11/27/2019 - 03:16
Chlorpyrifos is a type of organophosphate insecticide used extensively in the plantation of tomatoes, a worldwide popular food. However, chlorpyrifos residues on tomatoes bring risks to human health considering the consumption level of tomato is relatively high across many countries. Accurate detection and strict regulation of chlorpyrifos residues are very important in controlling health risks...
Wed, 11/27/2019 - 03:16
Using longitudinal survey data from northern Ethiopia collected over 18 months, this study shows that conclusions about household food security are highly sensitive to measurement decisions. Especially important are 1) decisions about which food security indicators and cut-offs are chosen, and 2) whether analysis focuses on food security status at a given point in time or food security resilience...
Wed, 11/27/2019 - 03:15
Abstract Background Arsenic (As) and cadmium (Cd) are two toxic elements that have a relatively high risk of transfer from paddy soil to rice grain. Rice is a major dietary source of these two elements for populations consuming rice as a staple food. Reducing their accumulation in rice grain is important for food safety and human health. Scope We review recent progress in understanding the...
Wed, 11/27/2019 - 03:15
Salmonella biofilms act as a continuous source for cross-contamination in the food processing environments. In this study, a stable rugose morphotype of Salmonella was first induced by sequential exposure to subinhibitory concentrations (SICs) of sodium hypochlorite (NaOCl) (ranging from 50 to 300 ppm over 18-day period) in tryptic soy broth. Then, rugose and smooth morphotypes of Salmonella...
Wed, 11/27/2019 - 03:15
Edwardsiella piscicida is a pathogenic bacterium responsible for significant losses in important wild and cultured fish species. E. piscicida strain MS-18-199 recovered from a diseased hybrid catfish from East Mississippi and showed resistance to florfenicol, chloramphenicol, oxytetracycline, doxycycline, erythromycin, tetracycline, azitromycin, spectinomycin, sulfonamide, and bacitracin. To...
Wed, 11/27/2019 - 03:15
Enantioselectivity is usually ignored when assessing potential biochar-based methods of redressing pesticide contamination of soils. In this study, the effect of woodchip biochar (WBC) on the enantioselective dissipation of metalaxyl in soil and its uptake and translocation by lettuce were investigated. S-metalaxyl (T1/2 = 29.8 days) dissipated more quickly than R-metalaxyl (T1/2 = 36.4 days) in...
Wed, 11/27/2019 - 03:15
An earlier report described a human case of necrotizing fasciitis (NF) caused by mixed infection with 4 Aeromonas hydrophila strains (NF1–NF4). While the NF2, NF3, and NF4 strains were clonal and possessed exotoxin A (ExoA), the NF1 strain was determined to be phylogenetically distinct, harboring a unique type 6 secretion...
Wed, 11/27/2019 - 03:15
The study applied a targeted metabolomics approach that uses a direct injection and tandem mass spectrometry (DI–MS/MS) coupled with a liquid chromatography–tandem mass spectrometry (LC–MS/MS)-based metabolomics of plasma to evaluate the effects of supplementing clay with or without Saccharomyces cerevisiae fermentation product (SCFP) on the metabolic status of dairy...
Tue, 11/26/2019 - 03:25
by Anna Minchom, Daisy Mak, Ranga Gunapala, David Walder, Rajiv Kumar, Nadia Yousaf, Andrew Hodgkiss, Jaishree Bhosle, Sanjay Popat, Mary E. R. O’Brien Objectives Vitamin supplementation reduces pemetrexed toxicity. Raised plasma homocysteine reflects deficiency in vitamin B12 and folate, and is suppressed by supplementation. This observational study of 112 patients receiving pemetrexed-based...
Tue, 11/26/2019 - 03:17
Fusarium verticillioides is a fungal pathogen that is responsible for maize ear rot and stalk rot diseases worldwide. The fungus also produces carcinogenic mycotoxins, fumonisins, on infested maize. Unfortunately, we still lack clear understanding of how the pathogen responds to host and environmental stimuli to trigger fumonisin biosynthesis. The heterotrimeric G protein complex, consisting of...
Tue, 11/26/2019 - 03:16
A novel Gram-negative, aerobic, motile and rod-shaped bacterium with the potential to biodegrade polycyclic aromatic hydrocarbons, was isolated from Khazar (Caspian) Sea. Strain TBZ2T grows in the absence of NaCl and tolerates up to 8.5% NaCl. Growth occurred at pH 3.0–10.0 (optimum, pH 6.0–7.0) and 10–45 °C (optimum, 30 °C). The major fatty acids are C18:1ω7C, C16:1ω7C/ C15:0 iso 2-OH, C16:0,...
Tue, 11/26/2019 - 03:15
Serratia marcescens is an opportunistic human pathogen causing nosocomial infections and displays expanded resistance towards the conventional antibiotics. In S. marcescens, quorum sensing (QS) mechanism coordinates the population-dependent behaviors and regulates the virulence factors production. Photodynamic inactivation (PDI) is a promising alternative for the treatment of infections caused by...
Tue, 11/26/2019 - 03:15
Context-specific GEnome-scale metabolic Network REconstructions (GENREs) provide a means to understand cellular metabolism at a deeper level of physiological detail. Here, we use transcriptomics data from chemically-exposed rat hepatocytes to constrain a GENRE of rat hepatocyte metabolism and predict biomarkers of liver toxicity using the Transcriptionally Inferred Metabolic Biomarker Response...
Tue, 11/26/2019 - 03:15
The aryl hydrocarbon receptor (AhR) activation has been shown to alter proliferation, apoptosis, or differentiation of adult rat liver progenitors. Here, we investigated the impact of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-mediated AhR activation on a human model of bipotent liver progenitors, undifferentiated HepaRG cells. We used both intact undifferentiated HepaRG cells, and the cells with...
Tue, 11/26/2019 - 03:15
This study was performed to examine the transgenerational effects of bisphenol (BP) A analogs, BPE, and BPS on male reproductive functions using mice as a model. CD-1 mice (F0) were orally exposed to control treatment (corn oil), BPA, BPE, or BPS (0.5 or 50 µg/kg/day) from gestational day 7 (the presence of vaginal plug = 1) to birth. Mice from F1 and F2 offspring were used to generate F3 males....
Tue, 11/26/2019 - 03:15
Gestational exposure to bisphenol A (BPA) can lead to offspring insulin resistance. However, despite the role that the skeletal muscle plays in glucose homeostasis, it remains unknown whether gestational exposure to BPA, or its analog bisphenol S (BPS), impairs skeletal muscle development. We hypothesized that gestational exposure to BPA or BPS will impair fetal muscle development and lead to...
Tue, 11/26/2019 - 03:14
The enteric pathogen, Salmonella enterica is a major cause of human gastroenteritis globally and with increasing bacterial resistance to antibiotics, alternative solutions are urgently needed. Single domain antibodies (sdAbs), the smallest antibody fragments that retain antigen binding specificity and affinity, are derived from variable heavy-chain only fragments (VHH) of camelid heavy-chain-only...
Tue, 11/26/2019 - 03:14
The roles of signaling pathway genes related to the aflatoxin reduction trait in maize were studied for the improvement of maize resistance to the fungal pathogen Aspergillus flavus (A. flavus). In this study, 55 maize genes in plant–pathogen interaction signaling pathways were investigated among 12 maize near-isogenic lines (NILs) that carry maize quantitative trait loci (QTL) associated with...
Tue, 11/26/2019 - 03:14
Listeria monocytogenes is a Gram-positive bacterium that can be found in a broad range of environments, including soil, food, animals, and humans. L. monocytogenes can cause a foodborne disease manifesting as sepsis and meningo-encephalitis. To evaluate signals of selection within the core genome of neuroinvasive L. monocytogenes strains, we sequenced 122 L. monocytogenes strains from...
Tue, 11/26/2019 - 03:14
Conventionally, the delivery of biomolecules into bacteria for the generation of characterized or functional mutants has relied greatly on horizontal gene transfer techniques. However, the low compatibility of these techniques with novel or hard-to-transform bacteria currently serves as a challenge to the bioengineering field. Here, we explored the use of cell penetrating peptides (CPPs) as an...
Tue, 11/26/2019 - 03:14
This study investigated the aflatoxin production potentials of selected fungi using a polyphasic approach. Internally transcribed spacer region of the fungi was amplified using the polymerase chain reaction. Forty-five Aspergillus strains were further assessed for aflatoxin production using the conventional methods such as growth on yeast extract sucrose, β-cyclodextrin neutral red...
Tue, 11/26/2019 - 03:14
Espinoza-Vergara et al. unveiled a novel transmission mode of Vibrio cholerae based on environmental protozoan predation, which the bacterial pathogen evades via its release in ‘expelled food vacuoles.’ Vacuole-enclosed bacteria are not only fairly protected against environmental stressors, but also show enhanced intestinal colonization fitness upon oral ingestion.
Mon, 11/25/2019 - 03:25
Author(s): Mohamed Mammeri, Lara Cartou, Aurélie Chevillot, Myriam Thomas, Christine Julien, Isabelle Vallée, Bruno Polack, Jérôme Follet, Karim Tarik AdjouAbstractTo date, no information is available about the presence of Cryptosporidium spp. in French sheep, nor their potential role as zoonotic reservoirs. A total of 23 fecal samples were collected from diarrheic lambs (<11 days old) from...
Mon, 11/25/2019 - 03:24
Author(s): Yuanqing Kan, Lu Meng, Lingling Xie, Lixia Liu, Wenyue Dong, Jintao Feng, Yuchen Yan, Chao Zhao, Gang Peng, Decheng Wang, Mingfang Lu, Chen Yang, Chen NiuAbstractMacrophages are the first-line host defense that the invading Mycobacterium tuberculosis (Mtb) encounters. It has been recently reported that host aerobic glycolysis was elevated post the infection by a couple of virulent...
Mon, 11/25/2019 - 03:23
Author(s): Satoshi Nishida, Yasuo OnoAbstractBackground: Klebsiella pneumoniae carbapenemase (KPC)-producing Klebsiella pneumoniae has expanded rapidly and is associated with severe nosocomial infections. Last-line antibiotics such as colistin and tigecycline remain the only treatment option. Here, we describe the genetic background of a novel pan-resistant KPC-producing K. pneumoniae isolate...

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