Research Publications (Food Safety)

Author(s): Sanelisiwe Thinasonke Duze, Musa Marimani, Mrudula Patel

Author(s): Wenlong Huang, Xin Wang, Shukai Zheng, Ruotong Wu, Caixia Liu, Kusheng Wu

Cutaneous leishmaniasis (CL) is the most common form of leishmaniasis affecting human populations, yet CL remains largely ignored in drug discovery programs. CL causes disfiguring skin lesions and often relapses after “clinical cure” using existing therapeutics. To expand the pool of anti-CL lead candidates, we implemented an integrated screening platform comprising three progressive Leishmania parasite life cycle forms.

Listeria in food, are a serious risk to consumer’s health that may even have a fatal outcome. To analyze Listeria in food, the methods used must provide reliable results and detect all strains of Listeria. Several qPCR systems have been published for the identification of Listeria monocytogenes, innocua, ivanovii, welshimeri and seeligeri. PCR systems for Listeria spp. have also been published. However, they do not detect all known Listeria.

Acetochlor, a commonly used herbicide, and Pb are two important soil contaminants often found to co-occur. The cytotoxic effects of heavy metals like Pb considerably reduce the efficacy of microbial bioremediation steps undertaken to remove chemical contaminants from soil. This necessitates the identification of heavy metal-tolerant microbial strains that can degrade chemical pollutants.

Mycotoxins are secondary metabolites produced by fungal species that commonly have a toxic effect on human and animal health. Different foodstuff can be contaminated and are considered the major source of human exposure to mycotoxins, but occupational and environmental exposure can also significantly contribute to this problem.

Cyadox has potential use as an antimicrobial agent in animals. However, its pharmacodynamic properties have not been systematically studied yet. In this study, the in vitro antibacterial activities of cyadox were assayed, and the antibacterial efficacy of cyadox against facultative anaerobes was also determined under anaerobic conditions.

Botulinum neurotoxin type A (BoNT/A) is traditional medicine and well known for its therapeutic use as an anesthetic and in cosmetic applications that work through the inhibition of acetylcholine exocytosis in neuronal cells. BoNT/A also has the potential to function as a biological weapon due to its high mortality rate and ease of dispersal. Emerging evidence suggests that BoNT/A exhibits biological effects on nonneuronal cells.

Plasmid-mediated extended-spectrum beta-lactamase (ESBL), AmpC, and carbapenemase producing Enterobacteriaceae, in particular Escherichia coli and Klebsiella pneumoniae, with potential zoonotic transmission routes, are one of the greatest threats to global health. The aim of this study was to investigate global food products as potential vehicles for ESBL/AmpC-producing bacteria and identify plasmids harboring resistance genes.

Fresh produce has been identified as an important vehicle for the transmission of foodborne pathogens. This study evaluated the behavior of vegetative cells and spores of Bacillus thuringiensis, one of the main biological control agents (BCAs) used in the world, and Salmonella enterica on spinach plants (pre-harvest) and spinach cut leaves (post-harvest) at 12°C, experimentally inoculated as single or co-cultures.

Cronobacter sakazakii is an opportunistic food-borne pathogen that endangers the health of neonates and infants. This study aims to elucidate the antibacterial activity and mechanism of Chrysanthemum buds crude extract (CBCE) against C. sakazakii and its application as a natural disinfectant. The antibacterial activity was evaluated by the determination of the diameter of inhibition zone (DIZ), minimum inhibitory concentration (MIC), and minimum bactericide concentration (MBC).

Campylobacter jejuni is the leading cause of bacterial foodborne gastroenteritis world wide and represents a major public health concern. Over the past two decades, significant progress in functional genomics, proteomics, enzymatic-based virulence profiling (EBVP), and the cellular biology of C. jejuni have improved our basic understanding of this important pathogen. We review key advances in our understanding of the multitude of emerging virulence factors that influence the outcome of C.

Salmonella enterica is one of the most diverse and successful pathogens, representing a species with >2,600 serovars with a variety of adaptations that enable colonization and infection of a wide range of hosts. Fimbriae, thin hair-like projections that cover the surface of Salmonella, are thought to be the primary organelles that mediate Salmonella’s interaction with, and adherence to, the host intestinal epithelium, representing an important step in the infection process.

Many Gram-negative bacterial pathogens employ translocated virulence factors, termed effector proteins, to facilitate their parasitism of host cells and evade host anti-microbial defenses. However, eukaryotes have evolved to detect effector-mediated virulence strategies through a phenomenon termed effector-triggered immunity (ETI).

Background Susceptibility to Vibrio cholerae infection is affected by blood group, age, and preexisting immunity, but these factors only partially explain who becomes infected. A recent study used 16S ribosomal RNA amplicon sequencing to quantify the composition of the gut microbiome and identify predictive biomarkers of infection with limited taxonomic resolution. Methods To achieve increased resolution of gut microbial factors associated with V.

by Alyson R. Warr, Carole J. Kuehl, Matthew K. Waldor

by Paula Finamore-Araujo, Amanda Faier-Pereira, Carlos Ramon do Nascimento Brito, Eldrinei Gomes Peres, Klenicy Kazumy de Lima Yamaguchi, Renata Trotta Barroso Ferreira, Otacilio Cruz Moreira

Author(s): Eun Bi Jeon, Man-Seok Choi, Ji Yoon Kim, Eun Ha Choi, Jun Sup Lim, Jinsung Choi, Kwang Soo Ha, Ji Young Kwon, Sang Hyeon Jeong, Shin Young Park

Author(s): Henok Ashagrie Deribew, Ashagrie Zewdu Woldegiorgis

Author(s): Lingli Luo, Lanhua Yi, Jiaxin Chen, Bianfang Liu, Xin Lü

Author(s): Rongwei Han, Xinyu Liao, Chunmei Ai, Tian Ding, Jun Wang

Author(s): Eric Rottmann, Karen F. Hauke, Ulrich Krings, Ralf G. Berger

Author(s): Zhijun Guo, Jing Tian, Chengbi Cui, Yan Wang, Huanhuan Yang, Ming Yuan, Hansong Yu

Author(s): Hongfei Zhang, Sabrina Peiqi Chen, Hon Luen Seck, Weibiao Zhou

Author(s): Wen Li, Yinyuan Chen, Tao Wang