Research Publications from Peer-Reviewed Journals

The Research Publications track research that is published across national and international peer-reviewed journals. The most recent articles are available ahead of print and searchable by Journal Title, Subject, USDA Grant Funding Agencies or FDA Grant Funding Agencies. The research publications are tracked across five subject areas: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, and Viruses.

Sat, 03/20/2021 - 02:01
The bioaccumulation of arsenic (As) in the muscle, liver, kidneys, and brain of the shark Sphyrna lewini was measured in 40 juvenile specimens from southeast Gulf of California. Additionally, the biomagnification factor was calculated through prey items from stomach contents of the analyzed specimens. The concentrations of As (mg kg−1, wet weight) were higher in the muscle (10.1 ± 0.3) and liver...
Sat, 03/20/2021 - 02:01
Modified atmosphere packaging (MAP) is widely used for the preservation of fresh-cut fruit and vegetables. But many commercial polymeric films are limited to MAP applicability due to a low gas permeability of these films. Laser perforation is a novel method to provide micropores that raises gas permeability. Laser-induced micropore-based MAP (0, 2, 4, 6, 8 pores) and carbon-dot/chitosan (CDs/CH)...
Sat, 03/20/2021 - 00:00
Parkinson’s disease is the most common age-related motoric neurodegenerative disease. In addition to the cardinal motor symptoms of tremor, rigidity, bradykinesia, and postural instability, there are numerous non-motor symptoms as well. Among the non-motor symptoms, autonomic nervous system dysfunction is common. Autonomic symptoms associated with Parkinson’s disease include sialorrhea,...
Sat, 03/20/2021 - 00:00
Ochratoxin A (OTA) is a potential human carcinogen that poses a significant concern in food safety and public health. OTA has been found in a wide variety of agricultural commodities, including cereal grains. This study investigated the reduction of OTA during the preparation of rice- and oat-based porridge by a simulated indirect steam process. The effects of sodium bicarbonate (NaHCO3) and...
Fri, 03/19/2021 - 22:05
Letters in Applied Microbiology, Accepted Article. This study was conducted to isolate and identify ESBL‐producing Enterobacterales in conventional and organic chicken meats which were sold in Turkey. A total of 200 raw chicken meat sample (100 conventional and 100 organic) were used as material. Classic culture technique based on chromogenic method was used for the isolation of bacteria, and the...
Fri, 03/19/2021 - 16:00
Our understanding of the function of bacterial carbonic anhydrases (CAs, EC 4.2.1.1) has increased significantly in the last years. CAs are metalloenzymes able to modulate CO2, HCO3– and H+ concentration through their crucial role in catalysis of reversible CO2 hydration (CO2 + H2O ⇄ HCO3– + H+). In all living organisms, CA activity is linked to physiological processes, such as those related to...
Fri, 03/19/2021 - 16:00
This study was carried out to investigate the effects of mild heat, lactic acid, benzalkonium chloride and nisin treatments on the inactivation, sublethal injury, and subsequent growth of Listeria monocytogenes. Results showed that the Bigelow model successfully described the thermal inactivation kinetics, while the Log-linear model with tail consistently offered the most accurate fit to LA, BC,...
Fri, 03/19/2021 - 16:00
The conversion of mercury (Hg) to monomethylmercury (MMHg) is a critical area of concern in global Hg cycling. Periphyton biofilms may harbor significant amounts of MMHg but little is known about the Hg-methylating potential of the periphyton microbiome. Therefore, we used high-throughput amplicon sequencing of the 16S rRNA gene, ITS2 region, and Hg methylation gene pair (hgcAB) to characterize...
Fri, 03/19/2021 - 16:00
Microbial communities in insects are related to their geographical sources and contribute to adaptation to the local habitat. The Colorado potato beetle (Leptinotarsa decemlineata) (CPB) is a potato pest that causes serious economic losses in Xinjiang Uygur Autonomous Region (XJ) and Heilongjiang Province (HL), China. The influence of microorganisms in the invasion and dispersal of CPB is unclear...
Fri, 03/19/2021 - 16:00
Arsenic mobilization in groundwater systems is driven by a variety of functionally diverse microorganisms and complex interconnections between different physicochemical factors. In order to unravel this great ecosystem complexity, groundwaters with varying background concentrations and speciation of arsenic were considered in the Po Plain (Northern Italy), one of the most populated areas in...
Fri, 03/19/2021 - 16:00
The major objective of this study was to evaluate the inhibitory effect of essential oil (EO) from Zanthoxylum armatum DC. on Aspergillus flavus. The chemical composition of the EO was identified by gas chromatography–mass spectrometer. The minimum inhibitory concentration (MIC) of EO was investigated by liquid fermentation. The morphology, colony number, and aflatoxin content of A. flavus in...
Fri, 03/19/2021 - 16:00
The pathogenesis of type 2 diabetes mellitus (T2DM) is commonly associated with altered gut bacteria. However, whether the microbial dysbiosis that exists in human diabetic patients with or without retinopathy is different remains largely unknown. Here, we collected clinical information and fecal samples from 75 participants, including 25 diabetic patients without retinopathy (DM), 25 diabetic...
Fri, 03/19/2021 - 14:02
European Snacks Association (ESA) data on acrylamide in potato crisps from 2002 to 2019 (99704 observations) were analysed. Acrylamide levels have plateaued since 2011, although the lowest mean so far was attained in 2018 at 353 ± 2.7 ng g−1: a 54% reduction since 2002. The 85th, 90th and 95th quantiles did show evidence of continued downward progress, the 90th quantile being lower than the 750...
Fri, 03/19/2021 - 10:01
Quinoline antimalarials cause drug-induced electrocardiographic QT prolongation, a potential risk factor for torsade de pointes. The effects of currently used antimalarials on the electrocardiogram (ECG) were assessed in pregnant women with malaria. Pregnant women with microscopy-confirmed parasitemia of any malaria species were enrolled in an open-label randomized controlled trial on the...
Fri, 03/19/2021 - 10:01
A minimal genome and absent bacterial cell wall render Mycoplasma hominis inherently resistant to most antimicrobials except lincosamides, tetracyclines, and fluoroquinolones. Often dismissed as a commensal (except where linked to preterm birth), it causes septic arthritis in immunodeficient patients and is increasingly associated with transplant failure (particularly lung) accompanying...
Fri, 03/19/2021 - 10:01
We sought to determine if Acinetobacter baumannii is capable of altering the pharmacodynamics of an antistaphylococcal β-lactam. Two strains of methicillin-susceptible Staphylococcus aureus (MSSA) and two A. baumannii isolates were studied in 24-h static time-killing experiments under monoculture or coculture conditions. Bacterial killing of meropenem was described using an empirical...
Fri, 03/19/2021 - 10:01
Gonorrhea is a common, sexually transmitted disease caused by Neisseria gonorrhoeae. Multidrug-resistant N. gonorrhoeae is an urgent threat, and the development of a new antimicrobial agent that functions via a new mechanism is strongly desired. We evaluated the in vitro and in vivo activities of a DNA gyrase/topoisomerase IV inhibitor, TP0480066, which is a novel 8-(methylamino)-2-oxo-1,2-...
Fri, 03/19/2021 - 10:01
Synergy between piperacillin-tazobactam and meropenem against KPC-producing Klebsiella pneumoniae was recently demonstrated. We sought to test the combination against a broader range of serine carbapenemase producers. We tested the combination against 10 KPC-producing Escherichia coli and 10 OXA-48 family-producing K. pneumoniae isolates. Antibiotic concentrations used are achievable in...
Fri, 03/19/2021 - 10:01
The diazabicyclooctane (DBO) inhibitor avibactam (AVI) reversibly inactivates most serine β-lactamases, including the CTX-M β-lactamases. Currently, more than 230 unique CTX-M members distributed in five clusters with less than 5% amino acid sequence divergence within each group have been described. Recently, a variant named CTX-M-151 was isolated from a Salmonella enterica subsp....
Fri, 03/19/2021 - 10:01
Negamycin is a natural pseudodipeptide antibiotic with promising activity against Gram-negative and Gram-positive bacteria, including Enterobacteriaceae, Pseudomonas aeruginosa, and Staphylococcus aureus, and good efficacy in infection models. It binds to ribosomes with a novel binding mode, stimulating miscoding and inhibiting ribosome translocation. We were particularly interested in studying...
Fri, 03/19/2021 - 10:01
Screening strategies for antituberculosis compounds using Mycobacterium tuberculosis are time consuming and require biosafety level 3 (BSL3) facilities, which makes the development of high-throughput assays difficult and expensive. Mycobacterium marinum, a close genetic relative of M. tuberculosis, possesses several advantages as a suitable model for tuberculosis drug screening. However, despite...
Fri, 03/19/2021 - 08:02
by Aftab Nadeem, Athar Alam, Eric Toh, Si Lhyam Myint, Zia ur Rehman, Tao Liu, Marta Bally, Anna Arnqvist, Hui Wang, Jun Zhu, Karina Persson, Bernt Eric Uhlin, Sun Nyunt Wai Vibrio cholerae is a noninvasive intestinal pathogen extensively studied as the causative agent of the human disease cholera. Our recent work identified MakA as a potent virulence factor of V. cholerae in both Caenorhabditis...
Fri, 03/19/2021 - 08:01
by Mila Trementosa Garcia, Bruna Salani Mota, Natalia Cardoso, Ana Luiza Cabrera Martimbianco, Marcos Desidério Ricci, Filomena Marino Carvalho, Rodrigo Gonçalves, José Maria Soares Junior, José Roberto Filassi Background and objectives It is well established that tumor-free margin is an important factor for reducing local recurrence and reoperation rates. This systematic review with meta-...
Fri, 03/19/2021 - 08:01
by Momo Takemura, Takeshi Haneda, Hikari Idei, Tsuyoshi Miki, Nobuhiko Okada Nuclear factor-kappa B (NF-κB) plays a critical role in the host defense against microbial pathogens. Many pathogens modulate NF-κB signaling to establish infection in their host. Salmonella enterica serovar Typhimurium (S. Typhimurium) possesses two type III secretion systems (T3SS-1 and T3SS-2) and directly injects...
Fri, 03/19/2021 - 08:01
Author(s): Khursheed Ahmad Shiekh, Peng Zhou, Soottawat Benjakul (Source: Food Bioscience) Pulsed electric field (PEF) pre-treated Litopenaeus vannamei were immersed in Chamuang leaf extract (CLE) solutions (1 or 2%), followed by high voltage cold atmospheric plasma (HVCAP) in an argon/air (80:20) modified atmosphere for 10 min. Least melanosis scores were attained in the samples pre-treated with...
Fri, 03/19/2021 - 06:06
Author(s): Yves Waché, Anil Kumar Anal, Son Chu-Ky Food safety is mobilizing academics and professionals in South-East Asia (SEA) as it is not only important for the health of Asian consumers but also for exports. This domain is thus a priority for ASEAN as well as in the European strategy to control its importation. The project “Universities as key partners for the new challenges regarding...
Fri, 03/19/2021 - 06:06
Author(s): Ava Kharazi, Mostafa Leili, Mohammad Khazaei, Mohammad Yusef Alikhani, Reza Shokoohi In this study, 103 water, agricultural soil, and crops irrigated with wastewater or tube-well water were collected, and their heavy metal content was evaluated using inductively coupled plasma-mass spectrometry (ICP-MS). The Monte Carlo simulation method was used for exposure assessment and...
Fri, 03/19/2021 - 06:05
Author(s): Vathsala Mohan, Cristina D. Cruz, Arnoud H.M. van Vliet, Andrew R. Pitman, Sandra B. Visnovsky, Lucia Rivas, Brent Gilpin, Graham C. Fletcher Listeria monocytogenes is a foodborne human pathogen that causes systemic infection, fetal-placental infection in pregnant women causing abortion and stillbirth and meningoencephalitis in elderly and immunocompromised individuals. This study...
Fri, 03/19/2021 - 06:05
Author(s): Danae Siderakou, Evangelia Zilelidou, Sofia Poimenidou, Ioanna Tsipra, Eleni Ouranou, Konstantinos Papadimitriou, Panagiotis Skandamis The foodborne pathogen L. monocytogenes can be present in food processing environments where it is exposed to various stressors. These antimicrobial factors, which aim to eliminate the pathogen, can induce sub-lethal injury to the bacterial cells. In...
Fri, 03/19/2021 - 06:04
LWT
Author(s): Khashayar Shahin, Lili Zhang, Abbas Soleimani Delfan, Majid Komijani, Abolghasem Hedayatkhah, Hongduo Bao, Mohadeseh Barazandeh, Mojtaba Mansoorianfar, Maoda Pang, Tao He, Majid Bouzari, Ran Wang Shigella, the globally distributed causative agent of bacillary dysentery, is an important microbial contamination in raw and ready-to-eat foods. The recent commercial use of phage cocktails...
Fri, 03/19/2021 - 02:01
Abstract Occurrence of emerging antibiotic resistance genes (ARGs) in the environment, especially those conferring resistance to the last resort antibiotic carbapenems (blaKPC) and colistin (mcr-1), has become an important environmental issue. Real-time polymerase chain reaction (qPCR) methods were commonly used to quantify emerging ARGs in the environment, with some studies reporting high...
Fri, 03/19/2021 - 02:01
The objective of the study was to assess the heavy metal contamination in excreta of the Baya Weaver Bird (Ploceus philippinus). Samples were collected from nesting colony sites present in three districts viz. Ludhiana (location I), Ropar (location II) and Ferozepur (location III) falling in Central plain zone, Undulating plain zone and Western plain zone of Punjab respectively. In dry excreta...
Fri, 03/19/2021 - 02:01
Globally, Hepatitis E virus (HEV) causes over 20 million cases worldwide. HEV is an emerging and endemic pathogen within economically developed countries, chiefly resulting from infections with genotype 3 (G3) HEV. G3 HEV is known to be a zoonotic pathogen, with a broad host range. The primary source of HEV within more economically developed countries is considered to be pigs, and consumption of...
Fri, 03/19/2021 - 02:01
Due to the inadequate removal rates of drug residues in wastewater treatment plants (WWTP), the transition of these compounds into the environment has become a serious environmental problem for ecosystems and public health. In this study, occurrence, fate, and removal of widely consumed two antibiotics, ciprofloxacin (CIP) and sulfamethoxazole (SMX), selected from fluoroquinolone and sulfonamide...
Fri, 03/19/2021 - 00:00
Cordyceps fumosorosea, an insect pathogenic fungus, produces different toxins/secondary metabolites which can act as pest control agents. This study reports the extraction and characterization of crude mycelial extracts of C. fumosorosea isolate SP502 along with their bio-efficacy against Bemisia tabaci and Aphis craccivora. Fourier transform infrared spectroscopy, liquid chromatography, mass...
Fri, 03/19/2021 - 00:00
The kidney is threatened by a lot of potentially toxic substances. To study the influence of the nephrotoxin ochratoxin A (OTA) we established a cell co-culture model consisting of human renal proximal tubule cells and fibroblasts. We studied the effect of OTA on cell survival, the expression of genes and/or proteins related to cell death, extracellular matrix and energy homeostasis. OTA-induced...
Fri, 03/19/2021 - 00:00
Shiga toxins (Stxs) are classic bacterial toxins and major virulence factors of toxigenic Shigella dysenteriae and enterohemorrhagic Escherichia coli (EHEC). These toxins recognize a glycosphingolipid globotriaosylceramide (Gb3/CD77) as their receptor and inhibit protein synthesis in cells by cleaving 28S ribosomal RNA. They are the major cause of life-threatening complications such as hemolytic...
Fri, 03/19/2021 - 00:00
Food can be contaminated by various types of contaminants such as mycotoxins and toxic heavy metals. Therefore, it is very likely that simultaneous intake of more than one type of food contaminant by consumers may take place, which provides a strong rationale for investigating the combined toxicities of these food contaminants. Patulin is one of the most common food-borne mycotoxins, whereas...
Thu, 03/18/2021 - 22:05
Comprehensive Reviews in Food Science and Food Safety, EarlyView. Phenolic compounds are commonly incorporated into muscle foods to inhibit lipid oxidation and modify product flavor. Those that are present in or extracted from plant sources (seeds, leaves, and stems) known as “phytophenols” are of particular importance in the current meat industry due to natural origins, diversity, and safety...
Thu, 03/18/2021 - 18:01
Drug induced liver toxicity is a serious health complication leading to high mortality rates and post marketing withdrawal of drugs. Although considered to be the gold standard biomarkers; aspartate aminotransferase, alanine aminotransferase, total bilirubin and alkaline phosphatase have been found to have specificities beyond liver, therefore more specific and predictive markers for the...
Thu, 03/18/2021 - 16:00
Vibrio parahaemolyticus is the leading cause of seafood-associated bacterial gastroenteritis worldwide. Although different studies have focused on its pattern of variation over time, knowledge about the environmental factors driving the dynamics of this pathogen, within the Chilean territory, is still lacking. This study determined the prevalence of total and pathogenic V. parahaemolyticus...
Thu, 03/18/2021 - 16:00
Thailand is an agricultural country. However, agricultural productivity relies on the heavy use of herbicides, especially paraquat. Paraquat accumulation is emerging as a problem in an ever-growing portion of agricultural land. Paraquat residues are toxic to plants, animals, and aquatic organisms in the environment. Biological remediation is a process that can mitigate agricultural chemical...
Thu, 03/18/2021 - 16:00
Shiga toxin is the major virulence factor of enterohemorrhagic Escherichia coli (EHEC), and the gene encoding it is carried within the genome of Shiga toxin-converting phages (Stx phages). Numerous Stx phages have been sequenced to gain a better understanding of their contribution to the virulence potential of EHEC. The Stx phages are classified into the lambdoid phage family based on...
Thu, 03/18/2021 - 16:00
Enterotoxigenic E. coli (ETEC) is a common cause of diarrhea in children in low- and middle-income countries, and in travelers to these countries. ETEC is also an important cause of morbidity and premature mortality in piglets, calves, goat kids and lambs. The major virulence determinants of ETEC are enterotoxins and colonization factors, which enable the pathogen to colonize the small intestine...
Thu, 03/18/2021 - 16:00
Bacterial pathogens have a broad arsenal of genes that are tightly regulated and coordinated to facilitate adaptation to alter host inflammatory response and prolong intracellular bacterial survival. Salmonella enterica serovar Typhimurium utilizes a type III secretion system (T3SS) to deliver effector molecules into host cells and regulate signal transduction pathways such as NF-κB, thereby...
Thu, 03/18/2021 - 16:00
Pseudomonas aeruginosa is noted for its intrinsic antibiotic resistance and capacity of acquiring additional resistance genes. In this study, the genomes of nine clinical P. aeruginosa isolates were fully sequenced. An extensive genetic comparison was applied to 18 P. aeruginosa accessory genetic elements (AGEs; 13 of them were sequenced in this study and located within P. aeruginosa chromosomes...
Thu, 03/18/2021 - 16:00
Campylobacter jejuni is the leading bacterial cause of gastroenteritis worldwide with excessive incidence in low-and middle-income countries (LMIC). During a survey for C. jejuni from putative animal hosts in a town in the Peruvian Amazon, we were able to isolate and whole genome sequence two C. jejuni strains from domesticated guinea pigs (Cavia porcellus). The C. jejuni isolated from guinea...
Thu, 03/18/2021 - 10:01
Draft genomes of seven extended-spectrum β-lactamase (ESBL)-producing Escherichia coli strains recovered from New Zealand waterways are described. The mean genome size was 5.1 Mb, with 4,724 coding sequences. All genomes contained the ESBL gene blaCTX-M, and one carried a plasmid-mediated AmpC gene, blaCMY-2. A multidrug-resistant genotype was detected in three isolates.
Thu, 03/18/2021 - 10:01
ABSTRACT Periphytic biofilms have the potential to greatly influence the microbial production of the neurotoxicant monomethylmercury in freshwaters although few studies have simultaneously assessed periphyton mercury methylation and demethylation rates and the microbial communities associated with these transformations. We performed a field study on periphyton from a river affected by run-of-...
Thu, 03/18/2021 - 10:01
We report here the complete genome analysis of a clinical Campylobacter jejuni strain sequenced by a hybrid assembly approach. A hybrid assembly approach provided a complete genome sequence of C. jejuni that contains a 1,681,375-bp chromosome and 47,467-bp plasmid carrying various virulence and antimicrobial resistance determinants.

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