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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 25 of 4028

  1. Analysis and evaluation of in vitro bioaccessibility of aflatoxins B1, B2, G1 and G2 in plant-based milks

    • Food Chemistry
      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Magnetic Rice Husk Biochar for AFB1 Enrichment in Water, Rice and Maize: A Wash-Free Sensitivity Improvement Strategy for Immunochromatographic Test Strip

    • Water, Air, & Soil Pollution
    • The fungi in water distribution systems and drinking water have already been reported and can produce mycotoxins. In this study, a wash-free immunochromatographic test strip (ICTS) based on magnetic rice husk biochar for the ultrasensitive detection of Aflatoxin B1(AFB1) in water and grain has been developed. Magnetic rice husk biochar (MB) was a green nanomaterial, which was synthesized from rice hull and characterized. Fe3O4 was formed within the amorphous and granular MB.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. X-ray Irradiation Reduces Live Aspergillus flavus Viability but Not Aflatoxin B1 in Naturally Contaminated Maize

    • Toxins
    • Food crops around the world are commonly contaminated with Aspergillus flavus, which can produce the carcinogenic mycotoxin aflatoxin B1 (AFB1). The objective of this study is to test an X-ray irradiation sterilization method for studying AFB1 in contaminated maize samples in the laboratory. Maize that had been naturally contaminated with 300 ppb AFB1 by the growth of aflatoxigenic A. flavus was ground and then irradiated at 0.0, 1.0, 1.5, 2.0, 2.5, and 3.0 kGy. A.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Beneficial effects of advanced chelate technology‐based 7‐minerals in aflatoxin‐B1 challenged broilers: toxin residue reduction, serum biochemical improvement and modulation of the mRNA expression of NF‐kB and Nrf2, and genes within their pathways

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Organic trace minerals (TM) offer superior nutritional benefits because of their stable structure, making their addition to broiler diets potentially beneficial during challenging periods such as aflatoxin B1 (AFB1) contamination.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  5. Detection of zearalenone in miscellaneous beans by functionalized SERS sensor based on sea urchin aptamer

    • Food Chemistry
      • Natural toxins
      • Mycotoxins
  6. The influence of different abiotic conditions on the concentrations of free and conjugated deoxynivalenol and zearalenone in stored wheat

    • Mycotoxin Research
    • Environmental factors influence fungal growth and mycotoxin production in stored grains. However, the concentrations of free mycotoxins and their conjugates and how they are impacted by different interacting environment conditions have not been previously examined.

      • Natural toxins
      • Mycotoxins
  7. Distribution and safety evaluation of deoxynivalenol and its derivatives throughout the wheat product processing chain

    • Food Research International
      • Natural toxins
      • Mycotoxins
  8. Identification of mycotoxins in yogurt samples using an optimized QuEChERS extraction and UHPLC-MS/MS detection

    • Mycotoxin Research
    • Yogurt, a milk-derived product, is susceptible to mycotoxin contamination. While various methods have been developed for the analysis of dairy products, only a few have been specifically validated for yogurt. In addition, these methods are primarily focus on detecting aflatoxins and zearalenone. This study aimed to conduct a preliminary investigation into the presence of regulated, emerging, and modified mycotoxins in natural and oat yogurts available in the Spanish market.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. Mycotoxigenic Fusarium species and zearalenone concentration in commercial maize kernels in northern Ghana

    • Mycotoxin Research
    • The fungal genus Fusarium contains many toxigenic pathogens of maize with associated yield losses, reduction of grain quality, and accumulation of mycotoxins in harvested grains.

      • Natural toxins
      • Mycotoxins
  10. Bioenzymatic detoxification of mycotoxins

    • Frontiers in Microbiology
    • Mycotoxins are secondary metabolites produced during the growth, storage, and transportation of crops contaminated by fungi and are physiologically toxic to humans and animals. Aflatoxin, zearalenone, deoxynivalenol, ochratoxin, patulin, and fumonisin are the most common mycotoxins and can cause liver and nervous system damage, immune system suppression, and produce carcinogenic effects in humans and animals that have consumed contaminated food.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  11. Citrinin Provoke DNA Damage and Cell-Cycle Arrest Related to Chk2 and FANCD2 Checkpoint Proteins in Hepatocellular and Adenocarcinoma Cell Lines

    • Toxins
    • Citrinin (CIT), a polyketide mycotoxin produced by Penicillium, Aspergillus, and Monascus species, is a contaminant that has been found in various food commodities and was also detected in house dust. Several studies showed that CIT can impair the kidney, liver, heart, immune, and reproductive systems in animals by mechanisms so far not completely elucidated.

      • Natural toxins
      • Mycotoxins
  12. Investigation of ochratoxin A in air-dry-cured hams

    • Meat Science
      • Natural toxins
      • Mycotoxins
  13. Metabolome and Its Mechanism Profiling in the Synergistic Toxic Effects Induced by Co-Exposure of Tenuazonic Acid and Patulin in Caco-2 Cells

    • Toxins
    • Tenuazonic acid (TeA), usually found in cereals, fruits, vegetables, oil crops, and their products, was classified as one of the highest public health problems by EFSA as early as 2011, but it has still not been regulated by legislation due to the limited toxicological profile. Moreover, it has been reported that the coexistence of TeA and patulin (PAT) has been found in certain agricultural products; however, there are no available data about the combined toxicity.

      • Natural toxins
      • Mycotoxins
  14. Development and validation of extraction and clean-up procedures for UPLC-MS/MS analysis of aflatoxins in spices

    • Mycotoxin Research
    • UPLC-MS/MS analytical conditions for the analysis of aflatoxins in spices were optimized and validated in this study. Liquid-liquid partition-based protocols for the cleaning up of extracts using common organic solvents such as acetonitrile, hexane, and ethyl acetate were developed and validated. The developed liquid-liquid partition methods were compared with immuno-affinity column and QuEChERS clean-up methods for the UPLC-MS/MS analysis of aflatoxins in 8 spices.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. Individual and combined occurrences of the prevalent mycotoxins in commercial feline and canine food

    • Mycotoxin Research
    • Mycotoxins, such as aflatoxin B1 (AFB1), deoxynivalenol (DON), fumonisins (FBs), ochratoxin A (OTA), T-2 toxin (T-2), and zearalenone (ZEN), can contaminate animal feeds and pose risks to animal health and production performance. These mycotoxins are commonly found in cereals and grains, with the increased use of cereals in pet food, there is a rising concern about mycotoxin contamination among pet owners.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. Bt corn and cotton planting may benefit peanut growers by reducing aflatoxin risk

    • Plant Biotechnology Journal
    • Summary Decades of studies have shown that Bt corn, by reducing insect damage, has lower levels of mycotoxins (fungal toxins), such as aflatoxin and fumonisin, than conventional corn. We used crop insurance data to infer that this benefit from Bt crops extends to reducing aflatoxin risk in peanuts: a non‐Bt crop.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  17. Fungal community and toxigenic taxa in chestnut fruits in postharvest conditioning process and storage

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Chestnut fruit quality is affected by fungal contamination. The study of the patterns of contamination in the postharvest is crucial to individuate the critical phases and propose solutions. To understand how fungal colonization varies on fruits, the composition of mycobiota was investigated in postharvest handling and in between tissues (shell and kernel). RESULTS Fungal sequences were clustered into 308 operational taxonomic units (OTUs).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Protection against α-Amanitin-induced liver toxicity: Efficacy of pomegranate seed oil and black cumin oil

    • Toxicon
    • The consumption of mushrooms containing α-Amanitin (α-A) can lead to severe liver damage. In this study, toxicological experiments were conducted to confirm the protective effects of pomegranate seed oil (PSO) and black cumin oil (BCO) against α-A-induced hepatotoxicity.

      • Natural toxins
      • Mycotoxins
  19. Occurrence and risk estimation of zearalenone and deoxynivalenol in oats, wheat flour, and cereals consumed in Chile during 2016–2022

    • Journal of Food Composition and Analysis
    • Mycotoxin contamination in agricultural products is a significant food safety and public health concern globally. However, little is known about the occurrence and levels of deoxynivalenol (DON) and zearalenone (ZEN) in agri-food product in Chile.

      • Natural toxins
      • Mycotoxins
  20. Validation of the AgraStrip® Pro Total Aflatoxin WATEX® Method for Detection of Total Aflatoxins in Corn and Peanut Paste: AOAC Performance Tested MethodSM 032402

    • Journal of AOAC INTERNATIONAL
    • Background To protect public and animal health against risks provoked by aflatoxins contained therein, maximum limits for aflatoxins are defined. Limit values vary depending on the intended use and regulatory authority, therefore quantitative detection is essential.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Bioremediation of Aflatoxin B1 by Meyerozyma guilliermondii AF01 in Peanut Meal via Solid-State Fermentation

    • Toxins
    • The use of microorganisms to manage aflatoxin contamination is a gentle and effective approach. The aim of this study was to test the removal of AFB1 from AFB1-contaminated peanut meal by a strain of Meyerozyma guilliermondii AF01 screened by the authors and to optimize the conditions of the biocontrol. A regression model with the removal ratio of AFB1 as the response value was established by means of single-factor and response surface experiments.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Lycopene Alleviates Deoxynivalenol-induced Toxicity in Porcine Intestinal Epithelial Cells by Mediating Mitochondrial Function

    • Toxicology
    • Deoxynivalenol (DON) is widely found in food and feed, posing a threat to human and animal health. Lycopene (Lyc) is a natural plant extracts with significant antioxidant properties. This study was conducted to investigate the protective effects of Lyc on IPEC-J2 cells upon DON exposure. The detection of cell viability and trypan blue staining showed that Lyc alleviated cell damage and decreased cell apoptotic rate induced by DON.

      • Natural toxins
      • Mycotoxins
  23. Reduction of aflatoxins and ochratoxin A by addition of commercial Koji during fermentation of the Korean traditional soybean paste, Doenjang

    • Food Control
    • Contamination by aflatoxins and ochratoxin A of traditional Korean fermented soybean paste (Doenjang) is a serious food safety issue. In this study, we investigated the inhibitory effects of commercial Koji, a microbial starter culture used for fermentation, on mycotoxin contamination during Doenjang production at in vitro and scaled-up fermentation levels.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Vitamin 25(OH)D3, E, and C Supplementation Impact the Inflammatory and Antioxidant Responses in Piglets Fed a Deoxynivalenol-Contaminated Diet and Challenged with Lipopolysaccharides

    • Toxins
    • Using alternative ingredients or low-quality grain grades to reduce feeding costs for pig diets can introduce mycotoxins such as deoxynivalenol (DON) into feed, which is known to induce anorexia, inflammation, and oxidative stress. Adding vitamin 25(OH)D3 or vitamins E and C to the feed could increase piglets’ immune system to alleviate the effects of DON.

      • Natural toxins
      • Mycotoxins
  25. Efficiency evaluation of ordinary and nanoscale extracts of Agaricus bisporus. on inhibition mycelial growth and aflatoxin production of Aspergillus flavus in maize grain

    • Journal of Stored Products Research
    • This study aimed to protect maize crops from infection and production of Aspergillus flavus (A. flavus) aflatoxin B1(AFB1), using the ordinary and nanoscale extracts of Agaricus spp. HPLC technology showed that the isolate taken from Musayyib district which coded with (AFA5) was a highest toxin producer.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins