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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 15 of 15

  1. New Mutants of Epsilon Toxin from Clostridium perfringens with an Altered Receptor-Binding Site and Cell-Type Specificity

    • Toxins
    • Epsilon toxin (Etx) from Clostridium perfringens is the third most potent toxin after the botulinum and tetanus toxins. Etx is the main agent of enterotoxemia in ruminants and is produced by Clostridium perfringens toxinotypes B and D, causing great economic losses. Etx selectively binds to target cells, oligomerizes and inserts into the plasma membrane, and forms pores.

      • Bacterial pathogens
      • Clostridium botulinum
      • Clostridium perfringens
  2. Detection of toxins involved in foodborne diseases caused by Gram‐positive bacteria

    • Comprehensive Reviews in Food Science and Food Safety
    • Bacterial toxins are food safety hazards causing about 10% of all reported foodborne outbreaks in Europe. Pertinent to Gram‐positive pathogens, the most relevant toxins are emetic toxin and diarrheal enterotoxins of Bacillus cereus, neurotoxins of Clostridium botulinum, enterotoxin of Clostridium perfringens, and a family of enterotoxins produced by Staphylococcus aureus and some other staphylococci.

      • Clostridium perfringens
      • Clostridium botulinum
      • Staphylococcus aureus
      • Bacterial pathogens
      • Bacillus cereus
  3. A novel regulatory pathway consisting of a two-component system and an ABC-type transporter contributes to butanol tolerance in Clostridium acetobutylicum

    • Applied Microbiology and Biotechnology
    • Despite the long-term interest in solventogenic clostridia-based ABE (acetone-butanol-ethanol) fermentation, clostridial butanol tolerance and its underlying mechanism remain poorly understood, which is a major obstacle hindering further improvements of this important fermentative process.

      • Bacterial pathogens
      • Clostridium botulinum
      • Clostridium perfringens
  4. A multiplex PCR assay with a common primer for the detection of eleven foodborne pathogens

    • Journal of Food Science
    • Salmonella enterica, Listeria monocytogenes, Shigella flexneri, Escherichia coli O157:H7, Vibrio parahaemolyticus, Staphylococcus aureus, Vibrio cholerae, Clostridium botulinum type A, Bacillus cereus, Clostridium perfringens Alpha toxin, and Yersinia enterocolitica are 11 common foodborne pathogens. Traditional bacterial culture methods for detecting pathogens are time‐consuming and labor‐intensive.

      • Clostridium perfringens
      • Escherichia coli O157:H7
      • Listeria monocytogenes
      • Salmonella
      • Yersinia
      • Shigella
      • Vibrio
      • Staphylococcus aureus
      • Clostridium botulinum
      • Bacterial pathogens
      • Bacillus cereus
  5. Vaccine Production to Protect Animals Against Pathogenic Clostridia

    • Toxins
    • Clostridium is a broad genus of anaerobic, spore-forming, rod-shaped, Gram-positive bacteria that can be found in different environments all around the world. The genus includes human and animal pathogens that produce potent exotoxins that cause rapid and potentially fatal diseases responsible for countless human casualties and billion-dollar annual loss to the agricultural sector.

      • Clostridium botulinum
      • Clostridium perfringens
      • Bacterial pathogens
  6. Toxins, Vol. 11, Pages 525: Vaccine Production to Protect Animals Against Pathogenic Clostridia

    • Toxins
    • Toxins, Vol. 11, Pages 525: Vaccine Production to Protect Animals Against Pathogenic Clostridia

      Toxins doi: 10.3390/toxins11090525

      Authors:
      Zaragoza
      Orellana
      Moonen
      Moutafis
      Marcellin

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  7. Toxins, Vol. 11, Pages 472: Clostridium botulinum and Clostridium perfringens Occurrence in Kazakh Honey Samples

    • Toxins
    • Toxins, Vol. 11, Pages 472: Clostridium botulinum and Clostridium perfringens Occurrence in Kazakh Honey Samples

      Toxins doi: 10.3390/toxins11080472

      Authors:
      Balgabay Maikanov
      Raikhan Mustafina
      Laura Auteleyeva
      Jan Wiśniewski
      Krzysztof Anusz
      Tomasz Grenda
      Krzysztof Kwiatek
      Magdalena Goldsztejn
      Magdalena Grabczak

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  8. Role of Starter Cultures on the Safety of Fermented Meat Products

    • Frontiers in Microbiology
      • Bacterial pathogens
      • Bacillus cereus
      • Campylobacter
      • Clostridium botulinum
      • Clostridium perfringens
      • Listeria monocytogenes
      • Staphylococcus aureus
      • Yersinia
      • Chemical contaminants
      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. Toxigenic and pathogenic potential of enteric bacterial pathogens prevalent in the traditional fermented foods marketed in the Northeast region of India

    • International Journal of Food Microbiology
    • Available online 21 February 2019

      Author(s): Santosh Keisam, Ngangyola Tuikhar, Giasuddin Ahmed, Kumaraswamy Jeyaram

      • Clostridium perfringens
      • Listeria monocytogenes
      • Yersinia
      • Staphylococcus aureus
      • Clostridium botulinum
      • Bacterial pathogens
      • Bacillus cereus
  10. Toxins, Vol. 10, Pages 225: The Binary Toxin CDT of Clostridium difficile as a Tool for Intracellular Delivery of Bacterial Glucosyltransferase Domains

    • Toxins
    • Toxins, Vol. 10, Pages 225: The Binary Toxin CDT of Clostridium difficile as a Tool for Intracellular Delivery of Bacterial Glucosyltransferase Domains

      Toxins doi: 10.3390/toxins10060225

      Authors:
      Lara-Antonia Beer
      Helma Tatge
      Carmen Schneider
      Maximilian Ruschig
      Michael Hust
      Jessica Barton
      Stefan Thiemann
      Viola Fühner
      Giulio Russo
      Ralf Gerhard

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  11. Toxins, Vol. 9, Pages 247: Cellular Entry of Clostridium perfringens Iota-Toxin and Clostridium botulinum C2 Toxin

    • Toxins
    • Toxins, Vol. 9, Pages 247: Cellular Entry of Clostridium perfringens Iota-Toxin and Clostridium botulinum C2 Toxin

      Toxins doi: 10.3390/toxins9080247

      Authors:
      Masaya Takehara
      Teruhisa Takagishi
      Soshi Seike
      Masataka Oda
      Yoshihiko Sakaguchi
      Junzo Hisatsune
      Sadayuki Ochi
      Keiko Kobayashi
      Masahiro Nagahama

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  12. Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices

    • PLOS ONE
    • Cécile Féraudet-Tarisse, Christelle Mazuet, Serge Pauillac, Maren Krüger, Caroline Lacroux, Michel R. Popoff, Brigitte G. Dorner, Olivier Andréoletti, Marc Plaisance, Hervé Volland, Stéphanie Simon

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  13. Toxins, Vol. 8, Pages 237: Chloroquine Analog Interaction with C2- and Iota-Toxin in Vitro and in Living Cells

    • Toxins
    • C2-toxin from Clostridium botulinum and Iota-toxin from Clostridium perfringens belong both to the binary A-B-type of toxins consisting of two separately secreted components, an enzymatic subunit A and a binding component B that facilitates the entry of the corresponding enzymatic subunit into the target cells. The enzymatic subunits are in both cases actin ADP-ribosyltransferases that modify R177 of globular actin finally leading to cell death.

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  14. Use of Metagenomic Shotgun Sequencing Technology To Detect Foodborne Pathogens within the Microbiome of the Beef Production Chain [Public and Environmental Health Microbiology]

    • Applied and Environmental Microbiology
    • Foodborne illnesses associated with pathogenic bacteria are a global public health and economic challenge. The diversity of microorganisms (pathogenic and nonpathogenic) that exists within the food and meat industries complicates efforts to understand pathogen ecology. Further, little is known about the interaction of pathogens within the microbiome throughout the meat production chain.

      • Campylobacter
      • Clostridium perfringens
      • Listeria monocytogenes
      • Staphylococcus aureus
      • Clostridium botulinum
      • Bacterial pathogens
  15. Toxins, Vol. 8, Pages 101: EGA Protects Mammalian Cells from Clostridium difficile CDT, Clostridium perfringens Iota Toxin and Clostridium botulinum C2 Toxin

    • Toxins
    • The pathogenic bacteria Clostridium difficile, Clostridium perfringens and Clostridium botulinum produce the binary actin ADP-ribosylating toxins CDT, iota and C2, respectively. These toxins are composed of a transport component (B) and a separate enzyme component (A). When both components assemble on the surface of mammalian target cells, the B components mediate the entry of the A components via endosomes into the cytosol.

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
      • Chemical contaminants