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National Agricultural Library
U.S. Department of Agriculture
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  3. Research Publications (Food Safety)

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 8 of 8

  1. Inhibition of Toxoplasma gondii Growth by Dihydroquinine and Its Mechanisms of Action

    • Frontiers in Cellular and Infection Microbiology

    • Toxoplasma gondii is a zoonotic parasite that infects the brain of humans and causes cerebral toxoplasmosis. The recommended drugs for the treatment or prophylaxis of toxoplasmosis are pyrimethamine (PY) and sulfadiazine (SZ), which have serious side effects. Other drugs available for toxoplasmosis are poorly tolerated.

      • Chemical contaminants
      • Heavy Metals
      • Parasites
      • Toxoplasma gondii

  2. Surveillance for diseases, pathogens, and toxicants of muskrat (Ondatra zibethicus) in Pennsylvania and surrounding regions

    • PLOS ONE

    • by Laken S. Ganoe, Justin D. Brown, Matthew J. Lovallo, Michael J. Yabsley, Kayla B. Garrett, Alec T. Thompson, Robert H. Poppenga, Mark G. Ruder, W. David Walter

      • Heavy Metals
      • Toxoplasma gondii
      • Bacterial pathogens
      • Chemical contaminants
      • Parasites

  3. Treatment with melatonin induces a reduction of Toxoplasma gondii development in LLC-MK2 cells

    • Parasitology Research

    • It is known that the current treatment for toxoplasmosis causes side effects. Thus, it is essential to develop new therapies with reduced adverse effects while concurrently maintaining broad coverage and prophylactic therapy. Melatonin is a hormone that participates in the circadian cycle in vertebrates and has antioxidant, immunomodulatory, and antitumoral functions.

      • Heavy Metals
      • Toxoplasma gondii
      • Parasites
      • Chemical contaminants

  4. Potent Tetrahydroquinolone Eliminates Apicomplexan Parasites

    • Frontiers in Cellular and Infection Microbiology

    • Apicomplexan infections cause substantial morbidity and mortality, worldwide. New, improved therapies are needed. Herein, we create a next generation anti-apicomplexan lead compound, JAG21, a tetrahydroquinolone, with increased sp3-character to improve parasite selectivity. Relative to other cytochrome b inhibitors, JAG21 has improved solubility and ADMET properties, without need for pro-drug.

      • Parasites
      • Heavy Metals
      • Toxoplasma gondii
      • Chemical contaminants

  5. A symbiotic bacterium of shipworms produces a compound with broad spectrum anti-apicomplexan activity

    • PLOS Pathogens

    • by Roberta M. O’Connor, Felix J. Nepveux V, Jaypee Abenoja, Gregory Bowden, Patricia Reis, Josiah Beaushaw, Rachel M. Bone Relat, Iwona Driskell, Fernanda Gimenez, Michael W. Riggs, Deborah A. Schaefer, Eric W. Schmidt, Zhenjian Lin, Daniel L. Distel, Jon Clardy, Timothy R. Ramadhar, David R. Allred, Heather M. Fritz, Pradipsinh Rathod, Laura Chery, John White

      • Chemical contaminants
      • Parasites
      • Heavy Metals
      • Toxoplasma gondii
      • Cryptosporidium parvum

  6. Localization and enzyme kinetics of aminopeptidase N3 from Toxoplasma gondii

    • Parasitology Research

    • Aminopeptidase N is an important metalloenzyme from the M1 zinc metallopeptidase family, which is present in numerous apicomplexan parasites, including Plasmodium, Eimeria, and Cryptosporidium. Aminopeptidase N is a potential drug target, and hence, its properties have been widely investigated. In the current study, the cellular localization and enzyme characteristics of Toxoplasma gondii aminopeptidase N3 (TgAPN3) were evaluated in vitro.

      • Chemical contaminants
      • Parasites
      • Antibiotic residues
      • Toxoplasma gondii
      • Cryptosporidium parvum
      • Bacterial pathogens

  7. Eukaryotic elongation factor 2 is involved in the anticoccidial action of diclazuril in the second-generation merozoites of Eimeria tenella

    • Veterinary Parasitology

    • Author(s): Bian-hua Zhou, Liu-shu Jia, Hong-wei Guo, Hai-yan Ding, Jing-yun Yang, Hong-wei Wang

      • Chemical contaminants
      • Parasites
      • Antibiotic residues
      • Toxoplasma gondii

  8. Efficacy of antiretroviral compounds against Toxoplasma gondii in vitro

    • International Journal of Antimicrobial Agents

    • Author(s): Jin-Lei Wang, Hany M. Elsheikha, Ting-Ting Li, Jun-Jun He, Meng-Jie Bai, Qin-Li Liang, Xing-Quan Zhu, Wei Cong

      • Toxoplasma gondii
      • Parasites
      • Heavy Metals
      • Chemical contaminants
      • Toxoplasma gondii
      • Chemical contaminants
      • Parasites