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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 25 of 47

  1. Establishment of a lethal mouse model of emerging tick-borne orthonairovirus infections

    • PLOS Pathogens
    • by Takuma Ariizumi, Koshiro Tabata, Yukari Itakura, Hiroko Kobayashi, William W. Hall, Michihito Sasaki, Hirofumi Sawa, Keita Matsuno, Yasuko Orba

      • Viruses
      • Hepatitis
  2. Thrombin cleavage of the hepatitis E virus polyprotein at multiple conserved locations is required for genome replication

    • PLOS Pathogens
    • by Danielle M. Pierce, Frazer J. T. Buchanan, Fraser L. Macrae, Jake T. Mills, Abigail Cox, Khadijah M. Abualsaoud, Joseph C. Ward, Robert A. S. Ariëns, Mark Harris, Nicola J. Stonehouse, Morgan R. Herod The genomes of positive-sense RNA viruses encode polyproteins that are essential for mediating viral replication. These viral polyproteins must undergo proteolysis (also termed polyprotein processing) to generate functional protein units.

      • Viruses
      • Hepatitis
  3. Constrained evolution of overlapping genes in viral host adaptation: Acquisition of glycosylation motifs in hepadnaviral precore/core genes

    • PLOS Pathogens
    • by Xupeng Hong, Stephan Menne, Jianming Hu Hepadnaviruses use extensively overlapping genes to expand their coding capacity, especially the precore/core genes encode the precore and core proteins with mostly identical sequences but distinct functions. The precore protein of the woodchuck hepatitis virus (WHV) is N-glycosylated, in contrast to the precore of the human hepatitis B virus (HBV) that lacks N-glycosylation.

      • Viruses
      • Hepatitis
  4. Genetic diversity of collaborative cross mice enables identification of novel rift valley fever virus encephalitis model

    • PLOS Pathogens
    • by Haley N. Cartwright, Dominique J. Barbeau, Joshua D. Doyle, Ed Klein, Mark T. Heise, Martin T. Ferris, Anita K. McElroy Rift Valley fever (RVF) is an arboviral disease of humans and livestock responsible for severe economic and human health impacts. In humans, RVF spans a variety of clinical manifestations, ranging from an acute flu-like illness to severe forms of disease, including late-onset encephalitis.

      • Viruses
      • Hepatitis
  5. Identification of NS2 determinants stimulating intrinsic HCV NS2 protease activity

    • PLOS Pathogens
    • by Olaf Isken, Thomas Walther, Luis Wong-Dilworth, Dirk Rehders, Lars Redecke, Norbert Tautz

      • Viruses
      • Hepatitis
  6. Host cell-dependent late entry step as determinant of Hepatitis B virus infection

    • PLOS Pathogens
    • by Xupeng Hong, Yuka Imamura Kawasawa, Stephan Menne, Jianming Hu Hepatitis B virus (HBV) has a highly restricted host range and cell tropism. Other than the human sodium taurocholate cotransporting polypeptide (huNTCP), the HBV entry receptor, host determinants of HBV susceptibility are poorly understood. Woodchucks are naturally infected with woodchuck hepatitis virus (WHV), closely related to HBV, but not with HBV.

      • Viruses
      • Hepatitis
  7. Guanosine inhibits hepatitis C virus replication and increases indel frequencies, associated with altered intracellular nucleotide pools

    • PLOS Pathogens
    • by Rosario Sabariegos, Ana María Ortega-Prieto, Luis Díaz-Martínez, Ana Grande-Pérez, Carlos García Crespo, Isabel Gallego, Ana I. de Ávila, Laura Albentosa-González, María Eugenia Soria, Pablo Gastaminza, Esteban Domingo, Celia Perales, Antonio Mas In the course of experiments aimed at deciphering the inhibition mechanism of mycophenolic acid and ribavirin in hepatitis C virus (HCV) infection, we observed an inhibitory effect of the nucleoside guanosine (Gua).

      • Viruses
      • Hepatitis
  8. H9N2 virus-derived M1 protein promotes H5N6 virus release in mammalian cells: Mechanism of avian influenza virus inter-species infection in humans

    • PLOS Pathogens
    • by Fangtao Li, Jiyu Liu, Jizhe Yang, Haoran Sun, Zhimin Jiang, Chenxi Wang, Xin Zhang, Yinghui Yu, Chuankuo Zhao, Juan Pu, Yipeng Sun, Kin-Chow Chang, Jinhua Liu, Honglei Sun

      • Viruses
  9. IRF3-mediated pathogenicity in a murine model of human hepatitis A

    • PLOS Pathogens
    • by Lu Sun, You Li, Ichiro Misumi, Olga González-López, Lucinda Hensley, John M. Cullen, David R. McGivern, Mami Matsuda, Ryosuke Suzuki, Ganes C. Sen, Asuka Hirai-Yuki, Jason K. Whitmire, Stanley M. Lemon

      • Hepatitis
      • Viruses
  10. Avian influenza A virus susceptibility, infection, transmission, and antibody kinetics in European starlings

    • PLOS Pathogens
    • by Jeremy W. Ellis, J. Jeffrey Root, Loredana M. McCurdy, Kevin T. Bentler, Nicole L. Barrett, Kaci K. VanDalen, Katherine L. Dirsmith, Susan A. Shriner

      • Viruses
  11. Genome-wide analyses of human noroviruses provide insights on evolutionary dynamics and evidence of coexisting viral populations evolving under recombination constraints

    • PLOS Pathogens
    • by Kentaro Tohma, Cara J. Lepore, Magaly Martinez, Juan I. Degiuseppe, Pattara Khamrin, Mayuko Saito, Holger Mayta, Amy U. Amanda Nwaba, Lauren A. Ford-Siltz, Kim Y. Green, Maria E. Galeano, Mirko Zimic, Juan A. Stupka, Robert H. Gilman, Niwat Maneekarn, Hiroshi Ushijima, Gabriel I. Parra

      • Norovirus
      • Viruses
  12. Evolution of the interactions between GII.4 noroviruses and histo-blood group antigens: Insights from experimental and computational studies

    • PLOS Pathogens
    • by Yu Liang, Wei Bu Wang, Jing Zhang, Jun Wei Hou, Fang Tang, Xue Feng Zhang, Li Fang Du, Ji Guo Su, Qi Ming Li

      • Norovirus
      • Antibiotic residues
      • Chemical contaminants
      • Viruses
  13. Genetic and biological properties of H7N9 avian influenza viruses detected after application of the H7N9 poultry vaccine in China

    • PLOS Pathogens
    • by Xin Yin, Guohua Deng, Xianying Zeng, Pengfei Cui, Yujie Hou, Yanjing Liu, Jingzhen Fang, Shuxin Pan, Dongxue Wang, Xiaohan Chen, Yaping Zhang, Xiurong Wang, Guobin Tian, Yanbing Li, Yan Chen, Liling Liu, Yasuo Suzuki, Yuntao Guan, Chengjun Li, Jianzhong Shi, Hualan Chen

      • Viruses
  14. Neuraminidase-associated plasminogen recruitment enables systemic spread of natural avian Influenza viruses H3N1

    • PLOS Pathogens
    • by Jacob Schön, Angele Breithaupt, Dirk Höper, Jacqueline King, Anne Pohlmann, Rokshana Parvin, Klaus-Peter Behr, Bernd-Andreas Schwarz, Martin Beer, Jürgen Stech, Timm Harder, Christian Grund

      • Viruses
      • Bacterial pathogens
  15. Norovirus evolution in immunodeficient mice reveals potentiated pathogenicity via a single nucleotide change in the viral capsid

    • PLOS Pathogens
    • by Forrest C. Walker, Ebrahim Hassan, Stefan T. Peterson, Rachel Rodgers, Lawrence A. Schriefer, Cassandra E. Thompson, Yuhao Li, Gowri Kalugotla, Carla Blum-Johnston, Dylan Lawrence, Broc T. McCune, Vincent R. Graziano, Larissa Lushniak, Sanghyun Lee, Alexa N. Roth, Stephanie M. Karst, Timothy J. Nice, Jonathan J. Miner, Craig B. Wilen, Megan T. Baldridge

      • Viruses
      • Norovirus
  16. Protective porcine influenza virus-specific monoclonal antibodies recognize similar haemagglutinin epitopes as humans

    • PLOS Pathogens
    • by Barbara Holzer, Pramila Rijal, Adam McNee, Basudev Paudyal, Veronica Martini, Becky Clark, Tanuja Manjegowda, Francisco J. Salguero, Emily Bessell, John C. Schwartz, Katy Moffat, Miriam Pedrera, Simon P. Graham, Alistair Noble, Marie Bonnet-Di Placido, Roberto M. La Ragione, William Mwangi, Peter Beverley, John W. McCauley, Rodney S. Daniels, John A. Hammond, Alain R. Townsend, Elma Tchilian

      • Viruses
  17. Human FcRn expression and Type I Interferon signaling control Echovirus 11 pathogenesis in mice

    • PLOS Pathogens
    • by Alexandra I. Wells, Kalena A. Grimes, Kenneth Kim, Emilie Branche, Christopher J. Bakkenist, William H. DePas, Sujan Shresta, Carolyn B. Coyne

      • Hepatitis
      • Viruses
  18. Selective usage of ANP32 proteins by influenza B virus polymerase: Implications in determination of host range

    • PLOS Pathogens
    • by Zhenyu Zhang, Haili Zhang, Ling Xu, Xing Guo, Wenfei Wang, Yujie Ji, Chaohui Lin, Yujie Wang, Xiaojun Wang

      • Viruses
  19. Convalescent serum therapy for COVID-19: A 19th century remedy for a 21st century disease

    • PLOS Pathogens
    • by Daniel Montelongo-Jauregui, Taissa Vila, Ahmed S. Sultan, Mary Ann Jabra-Rizk

      • Viruses
      • COVID-19
  20. No more business as usual: Agile and effective responses to emerging pathogen threats require open data and open analytics

    • PLOS Pathogens
    • by Dannon Baker, Marius van den Beek, Daniel Blankenberg, Dave Bouvier, John Chilton, Nate Coraor, Frederik Coppens, Ignacio Eguinoa, Simon Gladman, Björn Grüning, Nicholas Keener, Delphine Larivière, Andrew Lonie, Sergei Kosakovsky Pond, Wolfgang Maier, Anton Nekrutenko, James Taylor, Steven Weaver

      • Viruses
      • COVID-19
  21. Footprint of the host restriction factors APOBEC3 on the genome of human viruses

    • PLOS Pathogens
    • by Florian Poulain, Noémie Lejeune, Kévin Willemart, Nicolas A. Gillet

      • Viruses
      • COVID-19
  22. COVID-19 pandemic: Insights into structure, function, and hACE2 receptor recognition by SARS-CoV-2

    • PLOS Pathogens
    • by Anshumali Mittal, Kavyashree Manjunath, Rajesh Kumar Ranjan, Sandeep Kaushik, Sujeet Kumar, Vikash Verma

      • Viruses
      • COVID-19
  23. Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza

    • PLOS Pathogens
    • by Claire Scott, Jayakanth Kankanala, Toshana L. Foster, Daniel H. Goldhill, Peng Bao, Katie Simmons, Marieke Pingen, Matthew Bentham, Elizabeth Atkins, Eleni Loundras, Ruth Elderfield, Jolyon K. Claridge, Joseph Thompson, Peter R. Stilwell, Ranjitha Tathineni, Clive S. McKimmie, Paul Targett-Adams, Jason R. Schnell, Graham P. Cook, Stephen Evans, Wendy S. Barclay, Richard Foster, Stephen Griffin

      • Viruses
  24. Timelines of infection and transmission dynamics of H1N1pdm09 in swine

    • PLOS Pathogens
    • by Laetitia Canini, Barbara Holzer, Sophie Morgan, Johanneke Dinie Hemmink, Becky Clark, sLoLa Dynamics Consortium , Mark E. J. Woolhouse, Elma Tchilian, Bryan Charleston

      • Viruses
  25. Dynamic rotation of the protruding domain enhances the infectivity of norovirus

    • PLOS Pathogens
    • by Chihong Song, Reiko Takai-Todaka, Motohiro Miki, Kei Haga, Akira Fujimoto, Ryoka Ishiyama, Kazuki Oikawa, Masaru Yokoyama, Naoyuki Miyazaki, Kenji Iwasaki, Kosuke Murakami, Kazuhiko Katayama, Kazuyoshi Murata

      • Viruses
      • Norovirus