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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 25 of 665

  1. Ionizable copolymer functionalized magnetic nanocomposite as an adsorbent for boosting the extraction selectivity of aristolochic acids

    • Journal of Food and Drug Analysis
    • Aristolochic acid nephropathy (AAN) has drawn increasing public attention. Organic anion transporters (OATs) are considered to be responsible for mediating nephrotoxicity of aristolochic acids (AAs), as AAs are typical OAT1 substrates that exhibit anionic properties and contain one hydrophobic domain.

      • Chemical contaminants
      • Antibiotic residues
  2. Simultaneous Determination of Amphenicols in Animal-Derived Foods by Solvent and Solid Phase Extraction With Ultrahigh-Performance Liquid Chromatography Tandem Mass Spectrometry

    • Journal of AOAC INTERNATIONAL
    • Background The consumption of foods containing amphenicols, a type of antibiotic, is a major concern for human health. A stable and accurate detection method can provide technical support for food-safety monitoring. Objective An effective and efficient method was established for determining amphenicols in animal-derived foods through the simultaneous use of solid-phase extraction (SPE) cleanup and ultrahigh-performance liquid chromatography/mass spectrometry (UPLC-MS/MS).

      • Chemical contaminants
      • Antibiotic residues
  3. Assessment and Assay Comparison for Detection of Antimicrobial Residues in Freshwater Aquaculture Fish in Erbil Governorate, Iraq

    • Antibiotics
    • The excessive and uncontrolled application of antibiotics in the fish farming industry, coupled with a lack of health monitoring and medication practices, is a driving force behind the escalating development of antimicrobial resistance. The present study assessed and compared qualitative field diffusion (QFD) and disk diffusion (DD) assays for the detection of antimicrobial residues (ARs) in diverse freshwater aquaculture fish.

      • Chemical contaminants
      • Antibiotic residues
  4. Comparison of filter membranes in the analysis of 183 veterinary and other drugs by liquid chromatography‐tandem mass spectrometry

    • Journal of Separation Science
    • Although filtration is one of the most common steps in sample preparation for chemical analysis, filter membrane materials can leach contaminants and/or retain some analytes in the filtered solutions. In multiclass, multiresidue analysis of veterinary drugs, it is challenging to find one type of filter membrane that does not retain at least some of the analytes before injection in ultrahigh‐performance liquid chromatography‐tandem mass spectrometry (UHPLC‐MS/MS).

      • Chemical contaminants
      • Antibiotic residues
  5. The presence of antibiotic residues in raw milk samples obtained after the withdrawal period and other quality parameters in relation to selected factors

    • Food Control
    • The aim of this study was to compare the results of the presence of antibiotic (AB) residues in the milk of dairy cows treated with ABs – during the withdrawal period (WP) and after the WP obtained by various screening tests (Delvotest T, Twinsensor BT020, and Eclipse 50), to evaluate the presence of AB residues with regard to selected factors (indication for AB administration, AB group, and a number of antimicrobial substances) and to assess selected parameters of milk quality (fat, crude pr

      • Chemical contaminants
      • Antibiotic residues
  6. Chemometric−Assisted QuEChERS Method for Multiresidue Analysis of Veterinary Drugs in Pigeon Muscle by LC-MS/MS

    • Food Analytical Methods
    • Pigeon is an essential poultry with tasty meat and high protein content, and its breeding and consumption of meat have been increasing annually. Nevertheless, technical bottlenecks still exist in detecting veterinary drug residues in pigeon muscle. A rapid and sensitive method for determining 67 veterinary drugs belonging to six major groups (quinolones, sulfonamides, macrolides, hormones, tetracyclines, and insecticides) was developed in pigeon muscle.

      • Chemical contaminants
      • Antibiotic residues
      • Pesticide residues
  7. Removal of antibiotic resistance genes during swine manure composting is strongly impaired by high levels of doxycycline residues

    • Waste Management
    • Antibiotic resistance genes (ARGs) are emerging pollutants that enter the farm and surrounding environment via the manure of antibiotic-treated animals. Pretreatment of livestock manure by composting decreases ARGs abundance, but how antibiotic residues affect ARGs removal efficiency remains poorly understood.

      • Chemical contaminants
      • Antibiotic residues
  8. Genomic Regions Associated with Resistance to Gastrointestinal Nematode Parasites in Sheep—A Review

    • Genes
    • Gastrointestinal nematodes (GINs) can be a major constraint and global challenge to the sheep industry. These nematodes infect the small intestine and abomasum of grazing sheep, causing symptoms such as weight loss, diarrhea, hypoproteinemia, and anemia, which can lead to death. The use of anthelmintics to treat infected animals has led to GIN resistance, and excessive use of these drugs has resulted in residue traced in food and the environment.

      • Chemical contaminants
      • Antibiotic residues
  9. Advancing Antibiotic Residue Analysis: LC-MS/MS Methodology for Ticarcillin Degradation Products in Tomato Leaves

    • Antibiotics
    • The indiscriminate use of antibiotics in agriculture has raised concerns about antibiotic residues in food products, necessitating robust analytical methods for detection and quantification. In this study, our primary aim was to develop a robust and advanced liquid chromatography-tandem mass spectrometry (LC-MS/MS) methodology specifically designed for the accurate quantification of ticarcillin degradation products in tomato leaves.

      • Chemical contaminants
      • Antibiotic residues
  10. Cross-sectional, commercial testing, and chromatographic study of the occurrence of antibiotic residues throughout an artisanal raw milk cheese production chain

    • Food Chemistry
    • This study investigated antibiotic utilization in artisanal dairies and residue occurrence throughout the raw milk cheese production chain using commercial testing (Charm KIS and Eclipse Farm3G) and UHPLC-QqQ-MS/MS and LC-QqQ-MS/MS. The cross-sectional survey results revealed gaps in the producers’ knowledge of antibiotic use.

      • Chemical contaminants
      • Antibiotic residues
  11. Effects of Antibiotic Residues on Fish Gut Microbiome Dysbiosis and Mucosal Barrier-Related Pathogen Susceptibility in Zebrafish Experimental Model

    • Antibiotics
    • The symbiotic community of microorganisms in the gut plays an important role in the health of the host. While many previous studies have been performed on the interactions between the gut microbiome and the host in mammals, studies in fish are still lacking. In this study, we investigated changes in the intestinal microbiome and pathogen susceptibility of zebrafish (Danio rerio) following chronic antibiotics exposure.

      • Chemical contaminants
      • Antibiotic residues
  12. Determination of Tilmicosin in Bovine, Swine, Chicken, and Turkey Tissues by Liquid Chromatography With Tandem Mass Spectrometry, Single-Laboratory Validation

    • Journal of AOAC INTERNATIONAL
    • Background An LC-MS/MS method was developed for determination and confirmation of tilmicosin in bovine, swine, chicken, and turkey tissues (liver, kidney, muscle, and skin/fat) and bovine milk. Objective The method was subjected to single-laboratory validation to establish method performance parameters.

      • Chemical contaminants
      • Antibiotic residues
  13. Analysis of quality and antibiotic residues in raw milk marketed informally in the Province of Pichincha – Ecuador

    • Food and Agricultural Immunology
    • In Ecuador, more than 50% of the milk produced was informally marketed, consequently, the mean of this study was to assess the quality of this milk specifically within the province of Pichincha, the largest milk producer. A total of 650 samples were gathered from the eight cantons within the province.

      • Chemical contaminants
      • Antibiotic residues
  14. Intrinsic and extrinsic pathways of apoptosis induced by multiple antibiotics residues and ocean acidification in hemocytes of scallop Argopecten irradians irradians: An interactionist perspective

    • Ecotoxicology and Environmental Safety
    • The increasing prevalence of antibiotics in seawater across global coastal areas, coupled with the ocean acidification induced by climate change, present a multifaceted challenge to marine ecosystems, particularly impacting the key physiological processes of marine organisms.

      • Chemical contaminants
      • Antibiotic residues
  15. Understanding Knowledge and Attitude of Farmers towards Antibiotic Use and Antimicrobial Resistance in Jhunjhunu District, Rajasthan India

    • Antibiotics
    • The misuse of antibiotics in veterinary practices by farmers is harming livestock production and food safety and leading to the rise of antibiotic resistance (AMR). This can also transfer resistant bacteria from animals to humans, posing a serious public health threat. However, we have not paid enough attention to understanding how farmers behave in this regard. Our study aims to explore farmers’ behaviors and identify the factors that influence their choices.

      • Chemical contaminants
      • Antibiotic residues
  16. Piperine: Chemistry and Biology

    • Toxins
    • Piperine is a plant-derived promising piperamide candidate isolated from the black pepper (Piper nigrum L.). In the last few years, this natural botanical product and its derivatives have aroused much attention for their comprehensive biological activities, including not only medical but also agricultural bioactivities.

      • Chemical contaminants
      • Antibiotic residues
      • Pesticide residues
  17. Chicken manure application alters microbial community structure and the distribution of antibiotic-resistance genes in rhizosphere soil of Cinnamomum camphora forests

    • FEMS Microbiology Ecology
    • The distribution of antibiotic-resistance genes (ARGs) in environmental soil is greatly affected by livestock and poultry manure fertilization, the application of manure will lead to antibiotic residues and ARGs pollution, and increase the risk of environmental pollution and human health. Cinnamomum camphora is an economically significant tree species in Fujian Province, China.

      • Chemical contaminants
      • Antibiotic residues
  18. Fabrication and characterization of fish gelatin-based magnetic nanocomposite for biomedical applications

    • World Journal of Microbiology and Biotechnology
    • Bionanocomposite is considered an advanced way to bridge the gap between the structural and functional material and achieve the desired properties in the nanocomposite. This present study highlighted the synthesis of fish gelatin-based magnetic nanocomposite (GMNC) using three different concentrations of gelatin (6% w/v, G12% w/v, and 18% w/v) individually, through the in situ coprecipitation method.

      • Chemical contaminants
      • Antibiotic residues
  19. Effects of dietary traditional Chinese medicine residues on growth performance, intestinal health and gut microbiota compositions in weaned piglets

    • Frontiers in Cellular and Infection Microbiology
    • Weaning stress can induce diarrhea, intestinal damage and flora disorder of piglets, leading to slow growth and even death of piglets. Traditional Chinese medicine residue contains a variety of active ingredients and nutrients, and its resource utilization has always been a headache.

      • Chemical contaminants
      • Antibiotic residues
  20. Validation of a Method Based on Liquid Chromatography-Tandem Mass Spectrometry for Multiclass Screening and Analysis of 59 Veterinary Drugs in Fishery Foods

    • Food Analytical Methods
    • Veterinary drugs (VDs) are regulated to prevent their abuse or misuse and protect humans that consume animal-based food products from exposure to VD residues. VD residues are managed according to the maximum residue limits (MRLs) or by prohibiting the use of VDs based on their residual properties and toxicities. However, all VD residues, even those that are not managed by MRLs, in animal-based food products will be regulated for public health improvement.

      • Chemical contaminants
      • Antibiotic residues
  21. Multi-residue detection of antibiotics in migratory goat milk and human health risk assessment in Western Himalayan region, India

    • Journal of Food Composition and Analysis
    • Occurrence of antibiotics in animal sourced foods not only affects economy but also poses potential health risks. The present study aimed to validate simultaneous detection of amoxicillin, penicillin – G and enrofloxacin in raw migratory goat milk (N=223) by HPLC-DAD and assess human health risks in Western Himalayan region, India.

      • Chemical contaminants
      • Antibiotic residues
  22. Development of a Solid-Phase Dispersive Extraction Method for Molecularly Imprinted Polymers and LC–MS/MS for Analysis of Clenbuterol Residues in Swine Livers and Kidneys

    • Journal of AOAC INTERNATIONAL
    • Background Clenbuterol (CLB) is approved as a veterinary drug because of its tracheal smooth muscle and uterine relaxant effects. However, if improperly administered for the purpose of fattening livestock, CLB can remain in the organs, which may pose a health hazard to humans.

      • Chemical contaminants
      • Antibiotic residues
  23. A review on photonic crystal materials in food detection

    • European Food Research and Technology
    • From farm to plate, food meets various challenges and pollution. Food detection is essential to ensure food safety. Although detection techniques have obtained great development, the accuracy, sensitivity and operating conditions still have room for improvement. Composed of dielectric media with different refractive indices to form a periodic structure, an optical material named photonic crystal (PC) can offer a breakthrough.

      • Chemical contaminants
      • Antibiotic residues
      • Pesticide residues
  24. Verification of documentation plausibility in equine passports–drug documentation for geldings in comparison to self-reported veterinarian drug usage for equine castrations in Germany

    • PLOS ONE
    • by Shary Tamara Schneider, Rudi Isbrandt, Heidrun Gehlen, Nina Langkabel, Diana Meemken The ‘positive list for equines’ (Regulation (EC) No 1950/2006) was implemented in the European Union in 2006. The drugs listed are approved for use in slaughter equines under certain conditions, although those drugs are not approved for use in livestock and are not listed in Table 1 of the annex to Regulation (EU) No 37/2010.

      • Chemical contaminants
      • Antibiotic residues
  25. Withdrawal time of danofloxacin and difloxacin and in vitro binding phenomenon to melanin in black‐boned silky fowl

    • Journal of Food Science
    • Abstract Fluoroquinolones are commonly used in poultry breeding. Few studies have evaluated the causes of serious drug residues in black‐boned silky fowl until enrofloxacin has been banned in black‐boned silky fowl breeding in the Chinese Veterinary Commission of Chinese Veterinary Pharmacopoeia (2020). However, similarly structured fluoroquinolones have not been studied in black‐boned silky fowl.

      • Chemical contaminants
      • Antibiotic residues