An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 1 - 24 of 24

  1. Safety verification for polysorbate 20, pharmaceutical excipient for intramuscular administration, in Sprague-Dawley rats and New Zealand White rabbits

    • PLOS ONE
    • by Junhyung Kim, Seongsung Kwak, Mi-Sun Park, Chang-Hoon Rhee, Gi-Hyeok Yang, Jangmi Lee, Woo-Chan Son, Won-ho Kang

      • Clostridium botulinum
      • Bacterial pathogens
  2. ‘Excessive sweating is not a feminine thing’: A qualitative study of women’s experiences suffering from primary hyperhidrosis

    • PLOS ONE
    • by Alexander Shayesteh, Margareta Persson, Christine Brulin, Elisabet Nylander

      Background

      Primary hyperhidrosis, excessive focal sweating is a common disease equally affecting men and women. Women tend to seek care more often and assess being more affected by hyperhidrosis in their daily life. The aim of this study was to explore experiences of living with primary hyperhidros in a sample of 15 women.

      Methods

      • Clostridium botulinum
      • Bacterial pathogens
  3. Efficacy of prolotherapy in comparison to other therapies for chronic soft tissue injuries: A systematic review and network meta-analysis

    • PLOS ONE
    • by Siew-Li Goh, Zulkarnain Jaafar, Yan-Nee Gan, Alston Choong, Jaspreet Kaur, Burak Kundakci, Samihah Abdul Karim, Muhammad Rahmani Jaffar, Mohamad Shariff A. Hamid

      Introduction

      • Clostridium botulinum
      • Bacterial pathogens
  4. Correction: Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study

    • PLOS ONE
    • by Atul T. Patel, Mark F. Lew, Khashayar Dashtipour, Stuart Isaacson, Robert A. Hauser, William Ondo, Pascal Maisonobe, Stefan Wietek, Bruce Rubin, Allison Brashear

      • Clostridium botulinum
      • Bacterial pathogens
  5. Sustained functional benefits after a single set of injections with abobotulinumtoxinA using a 2-mL injection volume in adults with cervical dystonia: 12-week results from a randomized, double-blind, placebo-controlled phase 3b study

    • PLOS ONE
    • by Atul T. Patel, Mark F. Lew, Khashayar Dashtipour, Stuart Isaacson, Robert A. Hauser, William Ondo, Pascal Maisonobe, Stefan Wietek, Bruce Rubin, Allison Brashear

      • Clostridium botulinum
      • Bacterial pathogens
  6. Refractory overactive bladder patients who chose sacral neuromodulation therapy after failed OnabotulinumtoxinA treatment: A systematic review and meta-analysis

    • PLOS ONE
    • by Guang Yang, Yong Xu, Genyi Qu, Yulong Zhang

      Objective

      To systematically review outcomes in patients with refractory overactive bladder (OAB) patients who underwent sacral neuromodulation therapy (SNM) therapy after unsuccessful onabotulinumtoxinA (BTX) therapy, and to compare outcomes with those who SNM as initial therapy.

      Methods

      • Clostridium botulinum
      • Bacterial pathogens
  7. Botulinum toxin in the treatment of partially accommodative esotropia with high AC/A ratio

    • PLOS ONE
    • by Jaime Tejedor, Francisco J. Gutiérrez-Carmona

      Purpose

      To study the outcome of botulinum toxin (BTX) treatment (group 1) in partially accommodative esotropia with high accommodative convergence/accommodation (AC/A) ratio, in comparison with bilateral medial rectus muscles recessions and posterior fixation (group 2).

      Methods

      • Clostridium botulinum
      • Bacterial pathogens
  8. Integrating a gait analysis test in hospital rehabilitation: A service design approach

    • PLOS ONE
    • by Javier Marín, Teresa Blanco, José J. Marín, Alejandro Moreno, Elena Martitegui, Juan C. Aragüés

      Background

      • Clostridium botulinum
      • Bacterial pathogens
  9. Botulinum toxin A injection into the entopeduncular nucleus improves dynamic locomotory parameters in hemiparkinsonian rats

    • PLOS ONE
    • by Adrianna R. Tsang, Nagalingam Rajakumar, Mandar S. Jog

      • Clostridium botulinum
      • Bacterial pathogens
  10. Therapeutic efficacy of equine botulism heptavalent antitoxin against all seven botulinum neurotoxins in symptomatic guinea pigs

    • PLOS ONE
    • by Douglas Barker, Karen T. Gillum, Nancy A. Niemuth, Shantha Kodihalli

      • Clostridium botulinum
      • Clostridium botulinum
      • Bacterial pathogens
  11. Botulinum toxin A-induced muscle paralysis stimulates Hdac4 and differential miRNA expression

    • PLOS ONE
    • Leah E. Worton, Edith M. Gardiner, Ronald Y. Kwon, Leah M. Downey, Brandon J. Ausk, Steven D. Bain, Ted S. Gross

      • Clostridium botulinum
      • Bacterial pathogens
  12. Proteomic analysis of four Clostridium botulinum strains identifies proteins that link biological responses to proteomic signatures

    • PLOS ONE
    • Brooke L. Deatherage Kaiser, Karen K. Hill, Theresa J. Smith, Charles H. D. Williamson, Paul Keim, Jason W. Sahl, Karen L. Wahl

      • Clostridium botulinum
      • Bacterial pathogens
  13. Inactivation of non-proteolytic Clostridium botulinum type E in low-acid foods and phosphate buffer by heat and pressure

    • PLOS ONE
    • Maximilian B. Maier, Tobias Schweiger, Christian A. Lenz, Rudi F. Vogel

      • Clostridium botulinum
      • Bacterial pathogens
  14. Botulinum toxin chemodenervation for childhood strabismus in England: National and local patterns of practice

    • PLOS ONE
    • Ameenat Lola Solebo, Anne-Marie Austin, Maria Theodorou, Chris Timms, Joanne Hancox, Gillian G. W. Adams

      Background

      • Clostridium botulinum
      • Bacterial pathogens
  15. Highly sensitive sandwich immunoassay and immunochromatographic test for the detection of Clostridial epsilon toxin in complex matrices

    • PLOS ONE
    • Cécile Féraudet-Tarisse, Christelle Mazuet, Serge Pauillac, Maren Krüger, Caroline Lacroux, Michel R. Popoff, Brigitte G. Dorner, Olivier Andréoletti, Marc Plaisance, Hervé Volland, Stéphanie Simon

      • Clostridium perfringens
      • Clostridium botulinum
      • Bacterial pathogens
  16. Molecular cloning, characterization and expression analysis of Frizzled 6 in the small intestine of pigs (Sus scrofa)

    • PLOS ONE
    • Lijun Zou, Xiaocheng Wang, Liping Jiang, Shengping Wang, Xia Xiong, Huansheng Yang, Wei Gao, Min Gong, Chien-An A. Hu, Yulong Yin

      • Clostridium botulinum
      • Bacterial pathogens
  17. A Rho-associated coiled-coil containing kinases (ROCK) inhibitor, Y-27632, enhances adhesion, viability and differentiation of human term placenta-derived trophoblasts in vitro

    • PLOS ONE
    • Kenichiro Motomura, Naoko Okada, Hideaki Morita, Mariko Hara, Masato Tamari, Keisuke Orimo, Go Matsuda, Ken-Ichi Imadome, Akio Matsuda, Takeshi Nagamatsu, Mikiya Fujieda, Haruhiko Sago, Hirohisa Saito, Kenji Matsumoto

      • Clostridium botulinum
      • Bacterial pathogens
  18. Heat shock and prolonged heat stress attenuate neurotoxin and sporulation gene expression in group I Clostridium botulinum strain ATCC 3502

    • PLOS ONE
    • Katja Selby, Gerald Mascher, Panu Somervuo, Miia Lindström, Hannu Korkeala

      • Clostridium botulinum
      • Bacterial pathogens
  19. A three monoclonal antibody combination potently neutralizes multiple botulinum neurotoxin serotype F subtypes

    • PLOS ONE
    • Yongfeng Fan, Consuelo Garcia-Rodriguez, Jianlong Lou, Weihua Wen, Fraser Conrad, Wenwu Zhai, Theresa J. Smith, Leonard A. Smith, James D. Marks

      • Clostridium botulinum
      • Bacterial pathogens
      • Chemical contaminants
  20. Grey Matter Microstructural Integrity Alterations in Blepharospasm Are Partially Reversed by Botulinum Neurotoxin Therapy

    • PLOS ONE
    • Hanganu Alexandru, Muthuraman Muthuraman, Venkata Chaitanya Chirumamilla, Nabin Koirala, Burcu Paktas, Günther Deuschl, Kirsten E. Zeuner, Sergiu Groppa

      Objective

      • Clostridium botulinum
      • Bacterial pathogens
  21. Cellular and Matrix Response of the Mandibular Condylar Cartilage to Botulinum Toxin

    • PLOS ONE
    • Eliane H. Dutra, Mara H. O’ Brien, Alexandro Lima, Zana Kalajzic, Aditya Tadinada, Ravindra Nanda, Sumit Yadav

      Objectives

      To evaluate the cellular and matrix effects of botulinum toxin type A (Botox) on mandibular condylar cartilage (MCC) and subchondral bone.

      Materials and Methods

      • Bacterial pathogens
      • Clostridium botulinum
  22. The Translocation Domain of Botulinum Neurotoxin A Moderates the Propensity of the Catalytic Domain to Interact with Membranes at Acidic pH

    • PLOS ONE
    • Anne Araye, Amélie Goudet, Julien Barbier, Sylvain Pichard, Bruno Baron, Patrick England, Javier Pérez, Sophie Zinn-Justin, Alexandre Chenal, Daniel Gillet

      • Clostridium botulinum
      • Bacterial pathogens
  23. Anti-Tumor Activity of Yuanhuacine by Regulating AMPK/mTOR Signaling Pathway and Actin Cytoskeleton Organization in Non-Small Cell Lung Cancer Cells

    • PLOS ONE
    • Ji In Kang, Ji-Young Hong, Hye-Jung Lee, Song Yi Bae, Cholomi Jung, Hyen Joo Park, Sang Kook Lee

      • Clostridium botulinum
      • Bacterial pathogens
  24. Presence of Cleaved Synaptosomal-Associated Protein-25 and Decrease of Purinergic Receptors P2X3 in the Bladder Urothelium Influence Efficacy of Botulinum Toxin Treatment for Overactive Bladder Syndrome

    • PLOS ONE
    • Hsin-Tzu Liu, Sung-Ho Chen, Michael B. Chancellor, Hann-Chorng Kuo

      Objectives

      To evaluate whether botulinum toxin A (BoNT-A) injection and Lipotoxin (liposomes with 200 U of BoNT-A) instillation target different proteins, including P2X3, synaptic vesicle glycoprotein 2A, and SNAP-25, in the bladder mucosa, leading to different treatment outcomes.

      Materials and Methods

      • Clostridium botulinum
      • Bacterial pathogens