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Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 38008

  1. Time Course of Age-Linked Changes in Photosynthetic Efficiency of Spirodela polyrhiza Exposed to Cadmium

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Plant Science
    • Short-term assessment of adverse effects is essential for populations exposed to higher risk of environmental pollution. This study presents the time course of physiological and morphological changes attributed to cadmium, emphasizing age-linked differences in the susceptibility of photosynthetic apparatus of Spirodela polyrhiza fronds exposed to different cadmium concentrations.

      • Chemical contaminants
      • Heavy Metals
  2. γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Plant Science
    • Postharvest deterioration can result in qualitative and quantitative changes in the marketability of horticultural commodities, as well as considerable economic loss to the industry. Low temperature and controlled atmosphere conditions (low O2 and elevated CO2) are extensively employed to prolong the postharvest life of these commodities. Nevertheless, they may suffer from chilling injury and other physiological disorders, as well as excessive water loss and bacterial/fungal decay.

      • Produce Safety
      • Fresh Cut
  3. 1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies. In a previous work, we found that several 1,4-dihydropyridine (DHP)-based antihypertensive drugs exhibited strong bactericidal activities against H. pylori by targeting the essential response regulator HsrA. To further evaluate the potential of 1,4-DHP as a scaffold for novel antimicrobials against H.

      • Bacterial pathogens
      • Staphylococcus aureus
  4. Establishment of Genome Based Criteria for Classification of the Family Desulfovibrionaceae and Proposal of Two Novel Genera, Alkalidesulfovibrio gen. nov. and Salidesulfovibrio gen. nov.

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • Bacteria in the Desulfovibrionaceae family, which contribute to S element turnover as sulfate-reducing bacteria (SRB) and disproportionation of partially oxidized sulfoxy anions, have been extensively investigated since the importance of the sulfur cycle emerged. Novel species belonging to this taxon are frequently reported, because they exist in various environments and are easy to culture using established methods.

      • Bacterial pathogens
      • Vibrio
  5. Untargeted Metabolomics Approach of Cross-Adaptation in Salmonella Enterica Induced by Major Compounds of Essential Oils

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • Cross-adaptation phenomena in bacterial populations, induced by sublethal doses of antibacterial solutions, are a major problem in the field of food safety. In this regard, essential oils and their major compounds appear as an effective alternative to common sanitizers in food industry environments.

      • Bacterial pathogens
      • Salmonella
  6. The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Cellular and Infection Microbiology
    • The persistence of erythrocytes infected with Plasmodium falciparum gametocytes in the bloodstream is closely related to the modulation of their mechanical properties. New drugs that increase the stiffness of infected erythrocytes may thus represent a novel approach to block malaria parasite transmission. The phosphodiesterase inhibitor tadalafil has been shown to impair the ability of infected erythrocytes to circulate in an in vitro model for splenic retention.

      • Chemical contaminants
      • Heavy Metals
  7. Targeting the Plasmodium falciparum’s Thymidylate Monophosphate Kinase for the Identification of Novel Antimalarial Natural Compounds

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Cellular and Infection Microbiology
    • Recent reports of resistance to artemisinin-based combination drugs necessitate the need to discover novel antimalarial compounds. The present study was aimed at identifying novel antimalarial compounds from natural product libraries using computational methods. Plasmodium falciparum is highly dependent on the pyrimidine biosynthetic pathway, a de novo pathway responsible for the production of pyrimidines, and the parasite lacks the pyrimidine salvage enzymes. The P.

      • Chemical contaminants
      • Antibiotic residues
      • Heavy Metals
  8. Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani

    • Wed, 05/25/2022 - 06:00
    • Toxins
    • Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively. The main habitat of these toxigenic bacteria is the environment (soil, sediments, cadavers, decayed plants, intestinal content of healthy carrier animals). C.

      • Bacterial pathogens
      • Clostridium botulinum
  9. A Retrospective Study on the Effectiveness and Safety of Vancomycin versus Daptomycin in Hemodialysis Patients

    • Wed, 05/25/2022 - 06:00
    • Antibiotics
    • Vancomycin or daptomycin is administered to hemodialysis patients infected with methicillin-resistant Staphylococcus and Enterococcus species. Although serious concerns regarding nephrotoxicity due to vancomycin have been raised, it might not be a critical issue in hemodialysis patients. Moreover, very few studies have investigated the effectiveness of vancomycin versus daptomycin in patients undergoing hemodialysis.

      • Bacterial pathogens
      • Staphylococcus aureus
  10. Mechanistic insight into the release behavior of arsenic (As) based on its geochemical fractions in the contaminated soils around lead/zinc (Pb/Zn) smelters

    • Wed, 05/25/2022 - 06:00
    • Journal of Cleaner Production
    • Arsenic was known as human carcinogen. It was therefore of great importance to better understanding the release behavior of arsenic in soils for managing and controlling the potential risks of smelter contaminated sites.

      • Chemical contaminants
      • Heavy Metals
  11. Dual transcriptome based reconstruction of Salmonella-human integrated metabolic network to screen potential drug targets

    • Wed, 05/25/2022 - 06:00
    • PLOS ONE
    • by Kadir Kocabaş, Alina Arif, Reaz Uddin, Tunahan Çakır Salmonella enterica serovar Typhimurium (S. Typhimurium) is a highly adaptive pathogenic bacteria with a serious public health concern due to its increasing resistance to antibiotics. Therefore, identification of novel drug targets for S. Typhimurium is crucial. Here, we first created a pathogen-host integrated genome-scale metabolic network by combining the metabolic models of human and S.

      • Bacterial pathogens
      • Salmonella
  12. Slipchip-based immunomagnetic separation combined with loop-mediated isothermal amplification for rapid detection of Bacillus cereus with tetracycline resistance gene tetL in pasteurized milk

    • Wed, 05/25/2022 - 06:00
    • Food Control
    • Rapid detection of antibiotic resistance genes (ARGs) of food microorganisms is critical for preventing the spread of ARGs via the food chain. In this study, slipchip-based immunomagnetic separation (IMS) combined with loop-mediated isothermal amplification (LAMP) was developed for rapid, specific, sensitive and multi-sample detection of Bacillus cereus with tetracycline resistance gene tetL in pasteurized milk. First, the magnetic nanoparticles coated with anti-B.

      • Bacterial pathogens
      • Bacillus cereus
  13. Antibacterial activity of a polyphenol-rich haskap (Lonicera caerulea L.) extract and tannic acid against Cronobacter spp.

    • Wed, 05/25/2022 - 06:00
    • Food Control
    • The antibacterial properties of methanolic haskap (Lonicera caerulea L.) berry extracts and tannic acid were examined against Cronobacter spp. with a view to determine their potential for the control of this human pathogen in powdered infant formula. The total phenolic content (TPC) and composition of methanolic extracts from three different cultivars were determined.

      • Bacterial pathogens
      • Cronobacter
  14. Determination of 43 pesticide residues in intact grape berries (Vitis Vinifera L.) by using an ultrasound-assisted acetonitrile extraction method followed by LC–MS/MS

    • Wed, 05/25/2022 - 06:00
    • Food Control
    • An ultrasound-assisted acetonitrile extraction method was applied for the determination of 43 pesticide residues in intact grape berries (Vitis Vinifera L.) by liquid chromatography-tandem mass spectrometry (LC–MS/MS). The results showed that ultrasound-assisted extraction from intact grape berries exhibited better efficiency than extraction from homogenized grape berries.

      • Chemical contaminants
      • Pesticide residues
  15. Behaviour and adhesion capacity of Listeria monocytogenes on Mozzarella di Bufala Campana PDO cheese and in fluids involved in the production process

    • Wed, 05/25/2022 - 06:00
    • Food Control
    • Listeria monocytogenes is a foodborne pathogen for humans. It can be found in ready-to-eat (RTE) products and its presence represents one of the biggest food safety concerns. Most of the cases of cheese contamination reported by the Rapid Alert System for Food and Feed (RASFF) in the last 10 years did not involve Mozzarella di Bufala Campana (MBC) Protected Designation of Origin (PDO) cheese.

      • Bacterial pathogens
      • Listeria monocytogenes
  16. Aflatoxin‐M1 contamination in cheese of six countries in the West Asia region: A systematic review and meta‐analysis

    • Wed, 05/25/2022 - 06:00
    • International Journal of Dairy Technology
    • International Journal of Dairy Technology, EarlyView. The aim of the present study was to assess Aflatoxin-M1 (AFM1) contamination in cheese samples from the West Asia region. Furthermore, AFM1 contamination was investigated based on the texture type (hard, semi-soft/semi-hard and soft) and the maturation process (matured and fresh) of the cheese sampled. Our results indicated that AFM1 contamination occurs in more than 50% of the cheese samples from all included countries.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  17. Natural Flavone Hispidulin Protects Mice from Staphylococcus aureus Pneumonia by Inhibition of α-Hemolysin Production via Targeting AgrAC

    • Wed, 05/25/2022 - 06:00
    • Microbiological Research
    • The emergence of drug-resistant Staphylococcus aureus (S. aureus) has limited drug options for the clinical treatment of S. aureus infections. Considering recent reports, therapeutic strategies targeting bacterial virulence hold great promise, and alpha-hemolysin (encoded by hla), a critical virulence factor of S. aureus, plays a vital role during bacterial infection.

      • Bacterial pathogens
      • Staphylococcus aureus
  18. Virulence adaption to environment promotes the age-dependent nasal colonization of Staphylococcus aureus

    • Wed, 05/25/2022 - 06:00
    • Emerging Microbes & Infections
    • Staphylococcus aureus is an important human commensal bacteria colonizing the human body, especially the nasal cavity. The nasal carriage can be a source of S. aureus bacteremia. However, the bacterial factors contributing to nasal colonization are not completely understood. By analysing S.

      • Bacterial pathogens
      • Staphylococcus aureus
  19. Molecular diagnostics and next-generation sequencing reveal real etiological characteristics of invasive Salmonella infection in febrile illness in Freetown, Sierra Leone

    • Wed, 05/25/2022 - 06:00
    • Emerging Microbes & Infections
    • Invasive Salmonella infection, which can cause typhoid/paratyphoid fever and invasive non-typhoidal salmonellosis, is a public health burden in Africa. Accurate diagnosis and etiological characterization are required to conduct prevalence and risk estimations for Salmonella infection; however, the utilization of optimal techniques and surveillance data are still insufficient.

      • Bacterial pathogens
      • Salmonella
  20. Niche Partitioning of Labyrinthulomycete Protists Across Sharp Coastal Gradients and Their Putative Relationships With Bacteria and Fungi

    • Tue, 05/24/2022 - 04:00
    • Frontiers in Microbiology
    • While planktonic microbes play key roles in the coastal oceans, our understanding of heterotrophic microeukaryotes’ ecology, particularly their spatiotemporal patterns, drivers, and functions, remains incomplete. In this study, we focus on a ubiquitous marine fungus-like protistan group, the Labyrinthulomycetes, whose biomass can exceed that of bacterioplankton in coastal oceans but whose ecology is largely unknown.

      • Produce Safety
      • Seasonal Produce
  21. Evaluation of Growth Performance, Nitrogen Balance and Blood Metabolites of Mutton Sheep Fed an Ammonia-Treated Aflatoxin B1-Contaminated Diet

    • Tue, 05/24/2022 - 04:00
    • Toxins
    • Experiments were conducted to evaluate the effects of an aflatoxin B1 (AFB1)-contaminated diet treated with ammonia on the diet detoxification and growth performance, nutrient digestibility, nitrogen utilization, and blood metabolites in sheep.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Therapeutic Approach to Botulinum Injections for Hemifacial Spasm, Synkinesis and Blepharospasm

    • Tue, 05/24/2022 - 04:00
    • Toxins
    • The aim of this study was to show our therapeutic outcome of botulinum injection to the facial muscles and thereby to find the best therapeutic concept which should be embraced. The decision to treat the lower eyelid with 1-point or 2-points injection was randomly taken as there is no consensus regarding this debate.

      • Bacterial pathogens
      • Clostridium botulinum
  23. Susceptibility Testing by Volatile Organic Compound Detection Direct from Positive Blood Cultures: A Proof-of-Principle Laboratory Study

    • Tue, 05/24/2022 - 04:00
    • Antibiotics
    • Bacteria produce volatile organic compounds (VOCs) during growth, which can be detected by colorimetric sensor arrays (CSAs). The SpecifAST® system (Specific Diagnostics) employs this technique to enable antibiotic susceptibility testing (AST) directly from blood cultures without prior subculture of isolates. The aim of this study was to compare the SpecifAST® AST results and analysis time to the VITEK®2 (bioMérieux) system.

      • Bacterial pathogens
      • Staphylococcus aureus
  24. Human health risk assessment of heavy metals from meat and offal of reindeer and cow in the Far North of European Russia

    • Tue, 05/24/2022 - 04:00
    • Scandinavian Journal of Public Health
    • Aims:This study aimed to compare the concentrations of heavy metals in reindeer and cow meat and offal originating from the Nenets Autonomous Okrug, Northwestern Russia, and to assess the risk to the health of the indigenous population associated with heavy metal intake due to the consumption of reindeer and cow.Methods:Lead, cadmium, mercury, and arsenic concentrations were measured in 39 muscle, 15 liver, and 14 kidney samples from reindeer and 33, 18, and 12 corresponding samples from cow

      • Chemical contaminants
      • Heavy Metals
  25. Rational Framework for the design of Trp- and Arg-rich peptide antibiotics against multidrug-resistant bacteria

    • Tue, 05/24/2022 - 04:00
    • Frontiers in Microbiology
    • The threat of antibiotic resistance warrants the discovery of agents with novel antimicrobial mechanisms. Antimicrobial peptides (AMPs) directly disrupting bacterial membranes may overcome resistance to traditional antibiotics. AMP development for clinical use has been mostly limited to topical application to date.

      • Chemical contaminants
      • Antibiotic residues