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Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 38022

  1. Biosynthesis of Phenolic Compounds and Antioxidant Activity in Fresh-Cut Fruits and Vegetables

    • Thu, 05/26/2022 - 04:00
    • Frontiers in Microbiology
    • Phenolic compounds are secondary metabolites and widely distributed in higher plants. When plants are subjected to injury stress, the rapid synthesis of more phenols is induced to result in injury defense response for wound healing and repair. Fresh-cut fruits and vegetables undergo substantial mechanical injury caused by pre-preparations such as peeling, coring, cutting and slicing. These processing operations lead to activate the biosynthesis of phenolic compounds as secondary metabolite.

      • Produce Safety
      • Fresh Cut
  2. Mucosa-Colonizing Microbiota Correlate With Host Autophagy Signaling in Patients With Inflammatory Bowel Disease

    • Thu, 05/26/2022 - 04:00
    • Frontiers in Microbiology
    • Both bacteria and autophagy are implicated in inflammatory bowel disease (IBD) pathogenesis. However, how bacteria crosstalk with autophagy signaling remains largely known, especially in intestinal mucosa. This study aimed to profile the internal complex autophagy signaling cascade and their external correlation with these bacteria, and consequently provide a systematic and precise target for future IBD diagnosis and therapy.

      • Bacterial pathogens
      • Shigella
  3. Intestinal Alkaline Phosphatase Prevents Sulfate Reducing Bacteria-Induced Increased Tight Junction Permeability by Inhibiting Snail Pathway

    • Thu, 05/26/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Tight junctions (TJs) are essential components of intestinal barrier integrity and protect the epithelium against passive paracellular flux and microbial translocation. Dysfunctional TJ leads to leaky gut, a condition associated with diseases including inflammatory bowel disease (IBD). Sulfate-Reducing Bacteria (SRB) are minor residents of the gut. An increased number of Desulfovibrio, the most predominant SRB, is observed in IBD and other diseases associated with leaky gut.

      • Bacterial pathogens
      • Vibrio
  4. Comparative Pharmacodynamics of Three Different Botulinum Toxin Type A Preparations following Repeated Intramuscular Administration in Mice

    • Thu, 05/26/2022 - 04:00
    • Toxins
    • Botulinum neurotoxin type A (BoNT/A) causes muscle paralysis by blocking cholinergic signaling at neuromuscular junctions and is widely used to temporarily correct spasticity-related disorders and deformities. The paralytic effects of BoNT/A are time-limited and require repeated injections at regular intervals to achieve long-term therapeutic benefits.

      • Bacterial pathogens
      • Clostridium botulinum
  5. Multi-Omics Reveal Additive Cytotoxicity Effects of Aflatoxin B1 and Aflatoxin M1 toward Intestinal NCM460 Cells

    • Thu, 05/26/2022 - 04:00
    • Toxins
    • Aflatoxin B1 (AFB1) is a common crop contaminant, while aflatoxin M1 (AFM1) is implicated in milk safety. Humans are likely to be simultaneously exposed to AFB1 and AFM1; however, studies on the combined interactive effects of AFB1 and AFM1 are lacking. To fill this knowledge gap, transcriptomic, proteomic, and microRNA (miRNA)-sequencing approaches were used to investigate the toxic mechanisms underpinning combined AFB1 and AFM1 actions in vitro.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Synergistic Effects of Bacteriophage vB_Eco4-M7 and Selected Antibiotics on the Biofilm Formed by Shiga Toxin-Producing Escherichia coli

    • Thu, 05/26/2022 - 04:00
    • Antibiotics
    • Apart from antibiotic resistance of pathogenic bacteria, the formation of biofilms is a feature that makes bacterial infections especially difficulty to treat. Shiga toxin-producing Escherichia coli (STEC) strains are dangerous pathogens, causing severe infections in humans, and capable of biofilm production. We have reported previously the identification and characterization of the vB_Eco4-M7 bacteriophage, infecting various STEC strains.

      • Bacterial pathogens
      • Enterohemorrhagic Escherichia coli
      • Escherichia coli O157:H7
  7. Use of β-cyclodextrin and milk protein-coated activated charcoal for rapid detection of Listeria monocytogenes in leafy greens by PCR without pre-enrichment

    • Thu, 05/26/2022 - 04:00
    • Food Control
    • Listeriosis outbreaks caused by contaminated leafy greens leaf have increased in recent years, which can pose a serious threat to public health. Thus, a rapid, precise, and effective detection method is urgently needed. We reported a novel sample pre-treatment that utilizes β-cyclodextrin and milk protein-coated activated charcoal to remove PCR inhibitors in leafy green matrices and facilitate the recovery of L. monocytogenes, which can be coupled with PCR subsequently.

      • Bacterial pathogens
      • Listeria monocytogenes
  8. Biofilm eradication ability of phage cocktail against Listeria monocytogenes biofilms formed on food contact materials and effect on virulence-related genes and biofilm structure

    • Thu, 05/26/2022 - 04:00
    • Food Research International
    • Listeria monocytogenes is a foodborne pathogen that can form biofilms in food processing facilities even under unfavorable growth environment. This study aimed to evaluate the biofilm eradication ability of Listeria-specific bacteriophage (phage) cocktail (LMPC01+02+03) against L. monocytogenes young (1 day) and mature (3 days) biofilms formed on food contact materials (FCMs: polyethylene, polypropylene, and stainless steel) at 4, 15, and 30 °C.

      • Bacterial pathogens
      • Listeria monocytogenes
  9. Clostridium sporogenes as surrogate for proteolytic C. botulinum - Development and validation of extensive growth and growth-boundary model

    • Thu, 05/26/2022 - 04:00
    • Food Microbiology
    • An extensive cardinal parameter growth and growth boundary model for C. sporogenes, as a surrogate for proteolytic C. botulinum, was developed to include the inhibitory effect of 11 environmental factors.

      • Bacterial pathogens
      • Clostridium botulinum
  10. Development of a highly sensitive and specific monoclonal antibody-based immunoassay for detection of okadaic acid in oysters and green mussels

    • Thu, 05/26/2022 - 04:00
    • Food and Agricultural Immunology
    • Okadaic acid (OA), one of marine biotoxins produced by several species of dinoflagellates, can accumulate in marine animals. The consumption of OA-contaminated seafood can cause diarrhoeic shellfish poisoning. Many countries have established regulatory restriction to limit the level of OA in seafood. In the present study, we report a highly sensitive monoclonal antibody (mAb) against OA produced by a new immunogen.

      • Natural toxins
      • Shellfish toxins
  11. A risk assessment model for Salmonella spp. in swine carcasses

    • Thu, 05/26/2022 - 04:00
    • EFSA Journal
    • EFSA Journal, Volume 20, Issue S1, May 2022. Salmonellosis is one of the most important food-borne outbreaks that occurs in the EU/EEA. From the first production stages at slaughter, meat is susceptible to spoilage and can be a substrate for the pathogenic microorganisms growth. Among the pathogens, the presence of Salmonella is mainly due to mishandling during the evisceration stage.

      • Bacterial pathogens
      • Salmonella
  12. Fleas from common rodent species are an unlikely source of plague (Yersinia pestis) in managed forests of northwestern Oregon, USA

    • Thu, 05/26/2022 - 04:00
    • Zoonoses and Public Health
    • Zoonoses and Public Health, EarlyView. Anthropogenic environmental change can alter the susceptibility of wildlife hosts to pathogens and provide an opportunity for disease emergence. We explored Yersinia pestis prevalence in fleas from three rodent species inhabiting intensively managed forests in Oregon, USA. Y. pestis was not detected in the 145 fleas (3 families and 9 species) collected.

      • Bacterial pathogens
      • Yersinia
  13. Bacteriophage therapy of human restricted Salmonella Species‐ A study in a surrogate bacterial and animal model

    • Thu, 05/26/2022 - 04:00
    • Letters in Applied Microbiology
    • Letters in Applied Microbiology, Accepted Article. Salmonella Typhi has been an important human restricted pathogen from time immemorial, and unfortunately, the indiscriminate use of antibiotics has induced the emergence of Multidrug-resistance in S. Typhi. Bacteriophage therapy may be a possible alternative in countering antimicrobial resistance.

      • Bacterial pathogens
      • Salmonella
  14. Residue and distribution of drip irrigation and spray application of two diamide pesticides in corn and dietary risk assessment for different consumer groups

    • Thu, 05/26/2022 - 04:00
    • Journal of the Science of Food and Agriculture
    • Journal of the Science of Food and Agriculture, Accepted Article. BACKGROUND As the use of diamide insecticides on corn continues to increase, there is growing concern about their residue levels on corn and dietary risks to populations.

      • Chemical contaminants
      • Pesticide residues
  15. Time Course of Age-Linked Changes in Photosynthetic Efficiency of Spirodela polyrhiza Exposed to Cadmium

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Plant Science
    • Short-term assessment of adverse effects is essential for populations exposed to higher risk of environmental pollution. This study presents the time course of physiological and morphological changes attributed to cadmium, emphasizing age-linked differences in the susceptibility of photosynthetic apparatus of Spirodela polyrhiza fronds exposed to different cadmium concentrations.

      • Chemical contaminants
      • Heavy Metals
  16. γ-Aminobutyrate Improves the Postharvest Marketability of Horticultural Commodities: Advances and Prospects

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Plant Science
    • Postharvest deterioration can result in qualitative and quantitative changes in the marketability of horticultural commodities, as well as considerable economic loss to the industry. Low temperature and controlled atmosphere conditions (low O2 and elevated CO2) are extensively employed to prolong the postharvest life of these commodities. Nevertheless, they may suffer from chilling injury and other physiological disorders, as well as excessive water loss and bacterial/fungal decay.

      • Produce Safety
      • Fresh Cut
  17. 1,4-Dihydropyridine as a Promising Scaffold for Novel Antimicrobials Against Helicobacter pylori

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • The increasing occurrence of multidrug-resistant strains of the gastric carcinogenic bacterium Helicobacter pylori threatens the efficacy of current eradication therapies. In a previous work, we found that several 1,4-dihydropyridine (DHP)-based antihypertensive drugs exhibited strong bactericidal activities against H. pylori by targeting the essential response regulator HsrA. To further evaluate the potential of 1,4-DHP as a scaffold for novel antimicrobials against H.

      • Bacterial pathogens
      • Staphylococcus aureus
  18. Establishment of Genome Based Criteria for Classification of the Family Desulfovibrionaceae and Proposal of Two Novel Genera, Alkalidesulfovibrio gen. nov. and Salidesulfovibrio gen. nov.

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • Bacteria in the Desulfovibrionaceae family, which contribute to S element turnover as sulfate-reducing bacteria (SRB) and disproportionation of partially oxidized sulfoxy anions, have been extensively investigated since the importance of the sulfur cycle emerged. Novel species belonging to this taxon are frequently reported, because they exist in various environments and are easy to culture using established methods.

      • Bacterial pathogens
      • Vibrio
  19. Untargeted Metabolomics Approach of Cross-Adaptation in Salmonella Enterica Induced by Major Compounds of Essential Oils

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Microbiology
    • Cross-adaptation phenomena in bacterial populations, induced by sublethal doses of antibacterial solutions, are a major problem in the field of food safety. In this regard, essential oils and their major compounds appear as an effective alternative to common sanitizers in food industry environments.

      • Bacterial pathogens
      • Salmonella
  20. The Phosphodiesterase Inhibitor Tadalafil Promotes Splenic Retention of Plasmodium falciparum Gametocytes in Humanized Mice

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Cellular and Infection Microbiology
    • The persistence of erythrocytes infected with Plasmodium falciparum gametocytes in the bloodstream is closely related to the modulation of their mechanical properties. New drugs that increase the stiffness of infected erythrocytes may thus represent a novel approach to block malaria parasite transmission. The phosphodiesterase inhibitor tadalafil has been shown to impair the ability of infected erythrocytes to circulate in an in vitro model for splenic retention.

      • Chemical contaminants
      • Heavy Metals
  21. Targeting the Plasmodium falciparum’s Thymidylate Monophosphate Kinase for the Identification of Novel Antimalarial Natural Compounds

    • Wed, 05/25/2022 - 06:00
    • Frontiers in Cellular and Infection Microbiology
    • Recent reports of resistance to artemisinin-based combination drugs necessitate the need to discover novel antimalarial compounds. The present study was aimed at identifying novel antimalarial compounds from natural product libraries using computational methods. Plasmodium falciparum is highly dependent on the pyrimidine biosynthetic pathway, a de novo pathway responsible for the production of pyrimidines, and the parasite lacks the pyrimidine salvage enzymes. The P.

      • Chemical contaminants
      • Antibiotic residues
      • Heavy Metals
  22. Regulatory Networks Controlling Neurotoxin Synthesis in Clostridium botulinum and Clostridium tetani

    • Wed, 05/25/2022 - 06:00
    • Toxins
    • Clostridium botulinum and Clostridium tetani are Gram-positive, spore-forming, and anaerobic bacteria that produce the most potent neurotoxins, botulinum toxin (BoNT) and tetanus toxin (TeNT), responsible for flaccid and spastic paralysis, respectively. The main habitat of these toxigenic bacteria is the environment (soil, sediments, cadavers, decayed plants, intestinal content of healthy carrier animals). C.

      • Bacterial pathogens
      • Clostridium botulinum
  23. A Retrospective Study on the Effectiveness and Safety of Vancomycin versus Daptomycin in Hemodialysis Patients

    • Wed, 05/25/2022 - 06:00
    • Antibiotics
    • Vancomycin or daptomycin is administered to hemodialysis patients infected with methicillin-resistant Staphylococcus and Enterococcus species. Although serious concerns regarding nephrotoxicity due to vancomycin have been raised, it might not be a critical issue in hemodialysis patients. Moreover, very few studies have investigated the effectiveness of vancomycin versus daptomycin in patients undergoing hemodialysis.

      • Bacterial pathogens
      • Staphylococcus aureus
  24. Mechanistic insight into the release behavior of arsenic (As) based on its geochemical fractions in the contaminated soils around lead/zinc (Pb/Zn) smelters

    • Wed, 05/25/2022 - 06:00
    • Journal of Cleaner Production
    • Arsenic was known as human carcinogen. It was therefore of great importance to better understanding the release behavior of arsenic in soils for managing and controlling the potential risks of smelter contaminated sites.

      • Chemical contaminants
      • Heavy Metals
  25. Dual transcriptome based reconstruction of Salmonella-human integrated metabolic network to screen potential drug targets

    • Wed, 05/25/2022 - 06:00
    • PLOS ONE
    • by Kadir Kocabaş, Alina Arif, Reaz Uddin, Tunahan Çakır Salmonella enterica serovar Typhimurium (S. Typhimurium) is a highly adaptive pathogenic bacteria with a serious public health concern due to its increasing resistance to antibiotics. Therefore, identification of novel drug targets for S. Typhimurium is crucial. Here, we first created a pathogen-host integrated genome-scale metabolic network by combining the metabolic models of human and S.

      • Bacterial pathogens
      • Salmonella