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Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 15728

  1. The Old Yellow Enzyme OfrA Fosters Staphylococcus aureus Survival via Affecting Thiol-Dependent Redox Homeostasis

    • Wed, 05/18/2022 - 05:00
    • Frontiers in Microbiology
    • Old yellow enzymes (OYEs) are widely found in the bacterial, fungal, and plant kingdoms but absent in humans and have been used as biocatalysts for decades. However, OYEs’ physiological function in bacterial stress response and infection situations remained enigmatic. As a pathogen, the Gram-positive bacterium Staphylococcus aureus adapts to numerous stress conditions during pathogenesis. Here, we show that in S. aureus genome, two paralogous genes (ofrA and ofrB) encode for two OYEs.

      • Bacterial pathogens
      • Staphylococcus aureus
  2. PVBase: A MALDI-TOF MS Database for Fast Identification and Characterization of Potentially Pathogenic Vibrio Species From Multiple Regions of China

    • Wed, 05/18/2022 - 05:00
    • Frontiers in Microbiology
    • The potentially pathogenic species of the genus Vibrio pose a threat to both humans and animals, creating medical burdens and economic losses to the mariculture industry. Improvements in surveillance and diagnosis are needed to successfully manage vibriosis outbreaks. Matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) can provide rapid diagnosis and has been widely used in the identification of Vibrio spp.

      • Bacterial pathogens
      • Vibrio
  3. FepR as a Central Genetic Target in the Adaptation to Quaternary Ammonium Compounds and Cross-Resistance to Ciprofloxacin in Listeria monocytogenes

    • Wed, 05/18/2022 - 05:00
    • Frontiers in Microbiology
    • The foodborne pathogen, Listeria monocytogenes, (Lm), frequently undergoes selection pressure associated with the extensive use of disinfectants, such as quaternary ammonium compounds, which are widely used in food processing plants.

      • Bacterial pathogens
      • Listeria monocytogenes
  4. Synergism between the Synthetic Antibacterial and Antibiofilm Peptide (SAAP)-148 and Halicin

    • Wed, 05/18/2022 - 05:00
    • Antibiotics
    • Recently, using a deep learning approach, the novel antibiotic halicin was discovered. We compared the antibacterial activities of two novel bactericidal antimicrobial agents, i.e., the synthetic antibacterial and antibiofilm peptide (SAAP)-148 with this antibiotic halicin.

      • Bacterial pathogens
      • Staphylococcus aureus
  5. A 3-alkylpyridine-bearing alkaloid exhibits potent antimicrobial activity against methicillin-resistant Staphylococcus aureus (MRSA) with no detectable resistance

    • Wed, 05/18/2022 - 05:00
    • Microbiological Research
    • Staphylococcus aureus is a Gram-positive bacterium responsible for a wide variety of infectious diseases, and its methicillin-resistant isolates pose a serious worldwide public health risk. New drugs are urgently needed for the treatment of methicillin-resistant Staphylococcus aureus (MRSA) infections.

      • Bacterial pathogens
      • Staphylococcus aureus
  6. Polyclonal hen egg yolk antibodies could confer passive protection against Salmonella serotypes in broiler chicks

    • Wed, 05/18/2022 - 05:00
    • Journal of Food Safety
    • Journal of Food Safety, EarlyView. Non-typhoidal Salmonella serotypes continue to be major food safety and public health threats worldwide. In the era of emerging antimicrobial resistance, it is imperative to search for alternative strategies of infection control. Present study deals with passive protection of young chicks using polyclonal egg yolk antibodies (IgY).

      • Bacterial pathogens
      • Salmonella
  7. Regulation of neutrophil myeloperoxidase inhibitor SPIN by the small RNA Teg49 in Staphylococcus aureus

    • Wed, 05/18/2022 - 05:00
    • Molecular Microbiology
    • Molecular Microbiology, Accepted Article. Teg49 is a S. aureus trans-acting regulatory sRNA derived from cleavage of the sarA P3 transcript. We showed here by RNA-Seq that the 5’ trident-like structure in Teg49 regulates transcriptionally (direct and indirect) 22 genes distinct from sarA.

      • Bacterial pathogens
      • Staphylococcus aureus
  8. Characterizing the Piezosphere: The Effects of Decompression on Microbial Growth Dynamics

    • Tue, 05/17/2022 - 04:00
    • Frontiers in Microbiology
    • The extent to which the full diversity of the subsurface microbiome can be captured via cultivation is likely hindered by the inevitable loss of cellular viability from decompression during sampling, enrichment, and isolation. Furthermore, the pressure tolerance of previously isolated strains that span surface and subsurface ecosystems can shed light into microbial activity and pressure adaptation in these transition zones.

      • Bacterial pathogens
      • Vibrio
  9. Gut Microbiome Characteristics in IgA Nephropathy: Qualitative and Quantitative Analysis from Observational Studies

    • Tue, 05/17/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Background

      Recent data indicate the importance of gut-kidney axis in the pathogenesis of Immunoglobulin A nephropathy (IgAN). Growing evidence suggests the alterations of diversity and composition of gut microbiome among patients with IgAN, however, the details are not yet fully understood.

      Methods

      • Bacterial pathogens
      • Shigella
  10. An Anti-MRSA Phage From Raw Fish Rinse: Stability Evaluation and Production Optimization

    • Tue, 05/17/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Accumulating evidence has denoted the danger of resistance in tenacious organisms like methicillin-resistant Staphylococcus aureus (MRSA). MRSA, a supple bacterium that adopts a variety of antibiotic resistance mechanisms, is the cause of multiple life-threatening conditions. Approaching a post-antibiotic era, bacteria-specific natural predators, bacteriophages, are now given the chance to prove eligible for joining the antibacterial weaponry.

      • Bacterial pathogens
      • Staphylococcus aureus
  11. “Alterations in the Skin Microbiota Are Associated With Symptom Severity in Mycosis Fungoides”

    • Tue, 05/17/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Cutaneous T cell lymphoma (CTCL), a non-Hodgkin lymphoma, is thought to arise from mature tissue-resident memory T cells. The most common subtypes include Mycosis Fungoides and Sezary Syndrome. The role of skin microbiota remains unclear in the symptom manifestation of MF.

      • Bacterial pathogens
      • Staphylococcus aureus
  12. Chitosan Silver and Gold Nanoparticle Formation Using Endophytic Fungi as Powerful Antimicrobial and Anti-Biofilm Potentialities

    • Tue, 05/17/2022 - 04:00
    • Antibiotics
    • Nanotechnology is emerging as a new technology with encouraging innovations. Global antibiotic use has grown enormously, with antibiotic resistance increasing by about 80 percent. In view of this alarming situation, intensive research has been carried out into biogenic nanoparticles and their antibacterial, antifungal, and antitumor activities.

      • Bacterial pathogens
      • Staphylococcus aureus
  13. Yersinia pseudotuberculosis doxycycline tolerance strategies include modulating expression of genes involved in cell permeability and tRNA modifications

    • Tue, 05/17/2022 - 04:00
    • PLOS Pathogens
    • by Hector S. Alvarez-Manzo, Robert K. Davidson, Jasper Van Cauwelaert de Wyels, Katherine L. Cotten, Benjamin Nguyen, Melody Xiao, Zeyu Zhu, Jon Anthony, Tim van Opijnen, Kimberly Michele Davis Antibiotic tolerance is typically associated with a phenotypic change within a bacterial population, resulting in a transient decrease in antibiotic susceptibility that can contribute to treatment failure and recurrent infections.

      • Bacterial pathogens
      • Yersinia
  14. Modeling the invasion of human small intestinal epithelial‐like cells by Salmonella enterica Typhimurium and Listeria monocytogenes using Bayesian inference

    • Tue, 05/17/2022 - 04:00
    • Letters in Applied Microbiology
    • Letters in Applied Microbiology, Accepted Article. In order to develop a mechanistic bacterial dose-response model, based on the concept of Key Events Dose-Response Framework (KEDRF), this study aimed to investigate the invasion of intestinal model cells (Caco-2) by Salmonella Typhimurium and Listeria monocytogenes and described the behavior of both pathogens as a mathematical model using Bayesian inference.

      • Bacterial pathogens
      • Listeria monocytogenes
      • Salmonella
  15. Lysinibacillus macroides mediated control of cellulose producing morphotype of Salmonella

    • Mon, 05/16/2022 - 04:00
    • Journal of the Science of Food and Agriculture
    • Journal of the Science of Food and Agriculture, Accepted Article. Background Soil dwelling human pathogens like Salmonella are transmitted by fresh produce like tomato, spinach, onion, cabbage etc. With >2600 serovars, it is difficult to classify the good plant colonizers from the non-colonizers. Generally, soil microbiota is classified as autochthonous or zymogenous organisms, based on their ability to survive in soil.

      • Bacterial pathogens
      • Salmonella
  16. Whole Genome Sequencing, Antibiotic Resistance, and Epidemiology Features of Nontyphoidal Salmonella Isolated From Diarrheic Children: Evidence From North China

    • Mon, 05/16/2022 - 04:00
    • Frontiers in Microbiology
    • Nontyphoidal Salmonella (NTS) in children remains a growing burden on public health and often causes children to be hospitalized with diarrheic symptoms. In this work, 260 strains of human Salmonella isolated from Jilin, China were characterized by serotypes and antimicrobial resistance using whole genome sequencing (WGS). The most prevalent serotype was Salmonella enteritidis (47.3%), followed by S. I 4,[5],12:i:- (33.1%), and Salmonella Typhimurium (7.3%).

      • Bacterial pathogens
      • Salmonella
  17. Bacterial Adhesion and Biofilm Formation of Enterococcus faecalis on Zwitterionic Methylmethacrylat and Polysulfones

    • Mon, 05/16/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Biofilm-associated implant infections represent a major challenge for healthcare systems around the world due to high patient burden and enormous costs incurred. Enterococcus faecalis (E. faecalis) is the most prevalent enterococcal species identified in biofilm-associated infections. The steadily growing areas of application of implants demand a solution for the control of bacterial infections.

      • Bacterial pathogens
      • Staphylococcus aureus
  18. Bacteriocin-Producing Probiotic Lactic Acid Bacteria in Controlling Dysbiosis of the Gut Microbiota

    • Mon, 05/16/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Several strains of lactic acid bacteria are potent probiotics and can cure a variety of diseases using different modes of actions. These bacteria produce antimicrobial peptides, bacteriocins, which inhibit or kill generally closely related bacterial strains and other pathogenic bacteria such as Listeria, Clostridium, and Salmonella. Bacteriocins are cationic peptides that kill the target cells by pore formation and the dissipation of cytosolic contents, leading to cell death.

      • Bacterial pathogens
      • Salmonella
  19. Capsaicin Potently Blocks Salmonella typhimurium Invasion of Vero Cells

    • Mon, 05/16/2022 - 04:00
    • Antibiotics
    • Salmonella typhimurium (S. typhimurium) is one of the major food and waterborne bacteria that causes several health outbreaks in the world. Although there are few antibiotics against this bacterium, some of these drugs are challenged with resistance and toxicity. To mitigate this challenge, our group explored the ethnomedicinal/herbalism knowledge about a certain spice used in Northern Ghana in West Africa against bacterial and viral infection. This plant is Capsicum chinense (C. chinense).

      • Bacterial pathogens
      • Salmonella
  20. Wild boars as reservoir for Campylobacter and Arcobacter

    • Sun, 05/15/2022 - 04:00
    • Veterinary Microbiology
    • Campylobacteriosis is a significant public health concern with Campylobacter jejuni and Campylobacter coli as main causative agents. Moreover, there is an increasing recognition of other pathogenic Campylobacter species and Campylobacter-like organisms as Arcobacter.

      • Bacterial pathogens
      • Campylobacter
  21. The impact of environmental pH on the gut microbiota community structure and short chain fatty acid production

    • Sun, 05/15/2022 - 04:00
    • FEMS Microbiology Ecology
    • Environmental pH is a critical parameter for maintenance of the gut microbiota. Here, the impact of pH on the gut microbiota luminal and mucosal community structure and short chain fatty acid (SCFA) production was evaluated in vitro, and data compiled to reveal a donor-independent response to an increase or decrease in environmental pH. The results found that raising environmental pH significantly increased luminal community richness and decreased mucosal community evenness.

      • Bacterial pathogens
      • Shigella
  22. Microbial Landscape and Antibiotic Susceptibility Dynamics of Skin and Soft Tissue Infections in Kazakhstan 2018–2020

    • Sat, 05/14/2022 - 04:00
    • Antibiotics
    • Skin and soft tissue inflammatory diseases of bacterial origin occupy a significant part of hospitalizations to emergency departments. One of the most common causes of sepsis is soft tissue infection, which accounts for about a quarter of all nosocomial infections. The aim of this study was to determine the differences in microbial landscape and antibiotic susceptibility of soft tissue infection pathogens among adults and children during the period 2018–2020.

      • Bacterial pathogens
      • Staphylococcus aureus
  23. Vibrio cholerae Chromosome Partitioning without Polar Anchoring by HubP

    • Sat, 05/14/2022 - 04:00
    • Genes
    • Partition systems are widespread among bacterial chromosomes. They are composed of two effectors, ParA and ParB, and cis acting sites, parS, located close to the replication origin of the chromosome (oriC). ParABS participate in chromosome segregation, at least in part because they serve to properly position sister copies of oriC. A fourth element, located at cell poles, is also involved in some cases, such as HubP for the ParABS1 system of Vibrio cholerae chromosome 1 (ch1).

      • Bacterial pathogens
      • Vibrio
  24. Derivatives of Esculentin-1 Peptides as Promising Candidates for Fighting Infections from Escherichia coli O157:H7

    • Sat, 05/14/2022 - 04:00
    • Antibiotics
    • New strategies are needed to fight the emergence of multidrug-resistant bacteria caused by an overuse of antibiotics in medical and veterinary fields. Due to the importance of biofilms in clinical infections, antibiofilm peptides have a great potential to treat infections. In recent years, an increased interest has emerged in antimicrobial peptides (AMPs). One of the richest sources of AMPs is represented by amphibian skin.

      • Bacterial pathogens
      • Enterohemorrhagic Escherichia coli
      • Escherichia coli O157:H7
  25. Epidemiological investigation on drug resistance of Salmonella isolates from duck breeding farms in Shandong Province and surrounding areas, China

    • Sat, 05/14/2022 - 04:00
    • Poultry Science
    • Duck salmonellosis is a common acute septic infectious disease that spreads rapidly, with serious harm to the duck breeding industry and public health. To date, there are few reports about the epidemiological characteristics of drug resistance in Salmonella from ducks. In this study, an epidemiological investigation was conducted on drug resistance of 110 Salmonella strains isolated from multiple duck farms in Shandong Province and surrounding areas, China.

      • Bacterial pathogens
      • Salmonella