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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 3525

  1. Intestinal secretory mechanisms in Okadaic acid induced diarrhoea

    • Thu, 10/06/2022 - 04:00
    • Food and Chemical Toxicology
      • Natural toxins
      • Shellfish toxins
  2. Sensitive and stable detection of deoxynivalenol based on electrochemiluminescence aptasensor enhanced by 0D/2D homojunction effect in food analysis

    • Thu, 10/06/2022 - 04:00
    • Food Chemistry
      • Natural toxins
      • Mycotoxins
  3. LC–MS/MS and GC–MS based phytochemical perspectives and antimicrobial effects of endophytic fungus Chaetomium ovatoascomatis isolated from Euphorbia milii

    • Tue, 10/04/2022 - 04:00
    • Archives of Microbiology
    • The antimicrobial activity of endophytic fungi isolated from Euphorbia milii was evaluated against Gram-positive, Gram-negative bacteria, unicellular yeast, and filamentous fungi. Chaetomium ovatoascomatis NRC was identified morphologically and genetically as the most active strain. The total ethyl acetate extract of C.

      • Bacterial pathogens
      • Bacillus cereus
      • Salmonella
      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Harvest and post-harvest handling practices associated with fumonisin B1 contamination in maize (Zea mays L.): dietary exposure and risk characterization in eastern Ethiopia

    • Tue, 10/04/2022 - 04:00
    • Mycotoxin Research
    • Maize is the main staple food crop in the eastern part of Ethiopia. However, maize loss is a major issue due to fungal contamination especially at the post-harvest stage owing to inadequate handling practices. This study aimed to assess post-harvest handling and awareness against fungal development and fumonisin B1 (FB1) in maize and to calculate risk exposures of FB1.

      • Natural toxins
      • Mycotoxins
  5. High performance aptasensing platform development through in silico aptamer engineering for aflatoxin B1 monitoring

    • Mon, 10/03/2022 - 13:00
    • Food Control
    • Due to the technical challenges of small binding aptamer development, reliable computational simulation studies can be considered as effective tools to design novel and high functional mycotoxin aptameric probes. Here, two novel aflatoxin B1(AFB1) binding aptamers were successfully exploited as recognition elements in the lateral flow aptasensors and the reflective phantom interface (RPI) platform.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Possible Toxic Mechanisms of Deoxynivalenol (DON) Exposure to Intestinal Barrier Damage and Dysbiosis of the Gut Microbiota in Laying Hens

    • Sat, 10/01/2022 - 04:00
    • Toxins
    • Deoxynivalenol is one the of most common mycotoxins in cereals and grains and causes a serious health threat to poultry and farm animals. Our previous study found that DON decreased the production performance of laying hens. It has been reported that DON could exert significant toxic effects on the intestinal barrier and microbiota.

      • Natural toxins
      • Mycotoxins
  7. Dual effects of zearalenone on aflatoxin B1–induced liver and mammary gland toxicity in pregnant and lactating rats

    • Sat, 10/01/2022 - 04:00
    • Ecotoxicology and Environmental Safety
    • Food and feed are frequently co-contaminated with aflatoxin B1 (AFB1) and zearalenone (ZEN). This study investigated the effects of ZEN on the AFB1–induced liver and mammary gland toxicity in pregnant and lactating rats.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  8. Time-Lagged Correlation Analysis of Shellfish Toxicity Reveals Predictive Links to Adjacent Areas, Species, and Environmental Conditions

    • Sat, 10/01/2022 - 04:00
    • Toxins
    • Diarrhetic Shellfish Poisoning (DSP) is an acute intoxication caused by the consumption of contaminated shellfish, which is common in many regions of the world. To safeguard human health, most countries implement programs focused on the surveillance of toxic phytoplankton abundance and shellfish toxicity levels, an effort that can be complemented by a deeper understanding of the underlying phenomena.

      • Natural toxins
      • Shellfish toxins
  9. Application of Non-Aflatoxigenic Aspergillus flavus for the Biological Control of Aflatoxin Contamination in China

    • Sat, 10/01/2022 - 04:00
    • Toxins
    • Biological control through the application of competitive non-aflatoxigenic Aspergillus flavus (A. flavus) to the soil during peanut growth is a practical method for controlling aflatoxin contamination. However, appropriate materials need to be found to reduce the cost of biocontrol products. In this study, a two-year experiment was conducted under field conditions in China, using a native non-aflatoxigenic strain to explore its effect.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Mini-review paper Lactobacillus plantarum and deoxynivalenol detoxification: a concise review

    • Fri, 09/30/2022 - 04:00
    • Journal of Food Protection
    • Mycotoxins are toxic secondary fungal metabolites that contaminate feeds, and their levels remain stable during feed processing. The economic impact of mycotoxins on animal production is mainly due to losses related to direct effects on animal health and trade losses related to grain rejection. Deoxynivalenol (DON) is a trichothecene mycotoxin with a worldwide prevalence of about 80%, which induces many toxic effects on human and animal health.

      • Natural toxins
      • Mycotoxins
  11. Can Red Yeast (Sporidiobolus pararoseus) Be Used as a Novel Feed Additive for Mycotoxin Binders in Broiler Chickens?

    • Fri, 09/30/2022 - 04:00
    • Toxins
    • Mycotoxin-contaminated feeds may negatively affect broiler chickens' health; hence, a sustainable approach to achieve mycotoxin elimination is necessary. This study aimed to evaluate the efficacy of red yeast (Sporidiobolus pararoseus; RY) as a novel mycotoxin binder in broilers. A total of 1440 one-week-old male broiler chicks were randomly assigned to 12 treatments in a 3 × 4 factorial design.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Zearalenone lactonase: characteristics, modification, and application

    • Fri, 09/30/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Zearalenone (ZEN) and its derivatives are one of the most contaminated fungal toxins worldwide, posing a severe threat to food security and human life. Traditional physical and chemical detoxifying methods are unsatisfactory due to incomplete detoxification, nutrient loss, and secondary pollutants. In recent years, bioremediation for eliminating fungal toxins has been gradually investigated.

      • Natural toxins
      • Mycotoxins
  13. Optimization of Aflatoxin B1-Lysine Analysis for Public Health Exposure Studies

    • Thu, 09/29/2022 - 04:00
    • Toxins
    • Aflatoxin B1 is a potent human carcinogen produced by several species of Aspergillus mainly found on nuts and maize. Exposures in parts of Africa, Latin America and Asia can be at multiples, sometimes orders of magnitude above tolerable daily levels. Although human exposure to aflatoxin can be estimated by analysis of the diet, only determination of the serum albumin aflatoxin adduct provides a health-relevant exposure measure.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  14. Atomic-scale simulations of the deoxynivalenol degradation induced by reactive oxygen plasma species

    • Thu, 09/29/2022 - 04:00
    • Food Research International
    • Deoxynivalenol (DON) is one of the most widely distributed and toxicologically dangerous mycotoxins. Cold atmospheric plasma (CAP) experiments have indicated a considerable degrading effect on DON, but the underlying interaction mechanism of plasma species and DON remains unknown.

      • Natural toxins
      • Mycotoxins
  15. A label-free aptasensor for dual-mode detection of aflatoxin B1 based on inner filter effect using silver nanoparticles and arginine-modified gold nanoclusters

    • Thu, 09/29/2022 - 04:00
    • Food Control
    • To avoid potential health risks associated with the ingestion of aflatoxin B1 (AFB1) contaminated foods, development of a simple and sensitive method for AFB1 detection is urgently needed. Herein, a label-free aptasensor for colorimetric/fluorometric dual-mode detection of AFB1 was developed. In the absence of AFB1, the aptamer-protected silver nanoparticles (AgNPs) were prevented from salt-induced aggregation and the solution remained yellow.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. Adsorption removal of ochratoxin A from milk by Tibetan kefir grains and its mechanism

    • Thu, 09/29/2022 - 04:00
    • LWT
    • Tibetan kefir grains (TKG) are microbial symbiotic starters used in various fermented foods. Recent studies have focused on removing toxin contaminants from food using TKG.

      • Natural toxins
      • Mycotoxins
  17. Novel mesoporous silica surface loaded gold nanocomposites SERS aptasensor for sensitive detection of zearalenone

    • Thu, 09/29/2022 - 04:00
    • Food Chemistry
    • Mycotoxin contamination is a severe threat to global food security, thus fast and effective detection of mycotoxins is of great significance. Herein, mesoporous silica surface loaded gold nanocomposites (MSN-Rh6G-AuNPs) were prepared as surface-enhanced Raman scattering (SERS) substrate, and the SERS aptasensor (MSN-Rh6G-AuNPs@apt) was further obtained by aptamer functionalization which can realize the quantitative and sensitive detection of zearalenone (ZEN).

      • Natural toxins
      • Mycotoxins
  18. Hierarchical CoCoPBA@PCN-221 nanostructure for the highly sensitive detection of deoxynivalenol in foodstuffs

    • Wed, 09/28/2022 - 04:00
    • Food Chemistry
    • An electrochemical impedimetric immunosensor was constructed based on a hierarchical nanostructured CoCo Prussian blue analogue entrapped by a Zr-based porphyrin MOF (denoted by CoCoPBA@PCN-221) for the sensitive detection of deoxynivalenol (DON).

      • Natural toxins
      • Mycotoxins
  19. Intraspecific Growth and Aflatoxin Inhibition Responses to Atoxigenic Aspergillus flavus: Evidence of Secreted, Inhibitory Substances in Biocontrol

    • Tue, 09/27/2022 - 04:00
    • Phytopathology®
    • The fungus Aspergillus flavus infects corn, peanut, and cottonseed, and contaminates seeds with acutely poisonous and carcinogenic aflatoxin. Aflatoxin contamination is a perennial threat in tropical and subtropical climates. Nonaflatoxin-producing isolates (atoxigenic) are deployed in fields to mitigate aflatoxin contamination. The biocontrol competitively excludes toxigenic A. flavus via direct replacement and thigmoregulated (touch) toxin inhibition mechanisms.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Effect of the Combined Compound Probiotics with Glycyrrhinic Acid on Alleviating Cytotoxicity of IPEC-J2 Cells Induced by Multi-Mycotoxins

    • Tue, 09/27/2022 - 04:00
    • Toxins
    • Aflatoxins B1 (AFB1), deoxynivalenol (DON) and zearalenone (ZEA) are the three most prevalent mycotoxins, whose contamination of food and feed is a severe worldwide problem.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. An Aflatoxin-M1 biochip using graphene quantum dot-gold hybrid nanoparticles

    • Sun, 09/25/2022 - 04:00
    • Food Chemistry
    • Toxicosis through food and feed has remained a point of concern to food sectors across the globe. Although strict regulations have been implemented in developed and developing countries, their detection in food matrices is an evolving science. This study focuses on the development and fabrication of an electrochemical microfluidic biosensor that deploys aptamers to detect trace concentrations of Aflatoxin-M1 (AF-M1) in milk samples.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Effects of Compound Mycotoxin Detoxifier on Alleviating Aflatoxin B1-Induced Inflammatory Responses in Intestine, Liver and Kidney of Broilers

    • Sun, 09/25/2022 - 04:00
    • Toxins
    • In order to alleviate the toxic effects of aflatoxins B1 (AFB1) on inflammatory responses in the intestine, liver, and kidney of broilers, the aflatoxin B1-degrading enzyme, montmorillonite, and compound probiotics were selected and combined to make a triple-action compound mycotoxin detoxifier (CMD). The feeding experiment was divided into two stages.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. High speed homogenization assisted encapsulation of synergistic essential oils formulation: Characterization, in vitro release study, safety profile, and efficacy towards mitigation of aflatoxin B1 induced deterioration in rice samples

    • Sun, 09/25/2022 - 04:00
    • Food and Chemical Toxicology
    • Application of essential oils to mitigate aflatoxin B1 (AFB1) contamination in food is a current research hotspot; however, their direct incorporation may cause toxic effects, and changes in food organoleptic properties.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Prediction of Aspergillus parasiticus inhibition and aflatoxin mitigation in red pepper flakes treated by pulsed electric field treatment using machine learning and neural networks

    • Sat, 09/24/2022 - 04:00
    • Food Research International
    • Presence of aflatoxins in agricultural products is a worldwide problem. Because of their high heat stability and resistance to most of the food processing technologies, aflatoxin degradation is still a big challenge.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Inhibition of Essential Oils on Growth of Aspergillus flavus and Aflatoxin B1 Production in Broth and Poultry Feed

    • Fri, 09/23/2022 - 04:00
    • Toxins
    • Aflatoxin B1 (AFB1), a common contaminant in food and feed during storage, does great harm to human and animal health. Five essential oils (thymol, carvacrol, cinnamaldehyde, eugenol, and citral) were tested for their inhibition effect against Aspergillus flavus (A. flavus) in broth and feed. Cinnamaldehyde and citral were proven to be most effective against A. flavus compared to others and have a synergistic effect when used simultaneously.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins