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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 126 - 150 of 3921

  1. Lipophilic Shellfish Poisoning Toxins in Marine Invertebrates from the Galician Coast

    • Toxins
    • For the purpose of assessing human health exposure, it is necessary to characterize the toxins present in a given area and their potential impact on commercial species.

      • Natural toxins
      • Shellfish toxins
  2. Efficacy of Two Commercially Available Adsorbents to Reduce the Combined Toxic Effects of Dietary Aflatoxins, Fumonisins, and Zearalenone and Their Residues in the Tissues of Weaned Pigs

    • Toxins
    • Mycotoxins present a significant health concern within the animal-feed industry, with profound implications for the pig-farming sector.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. A 15-Year Retrospective Review of Ciguatera in the Madeira Islands (North-East Atlantic, Portugal)

    • Toxins
    • The first ciguatera fish poisoning (CFP) in Portugal dates from 2008 when 11 people reported CFP symptoms after consuming a 30 kg amberjack caught around the Selvagens Islands (Madeira Archipelago). Since then, 49 human poisonings have been reported. The emergence of a new threat challenged scientists and regulators, as methods for toxic microalgae analyses and ciguatoxin (CTX) detection were not implemented.

      • Natural toxins
      • Shellfish toxins
  4. An Occurrence and Exposure Assessment of Paralytic Shellfish Toxins from Shellfish in Zhejiang Province, China

    • Toxins
    • The intake of paralytic shellfish toxins (PSTs) may adversely affect human health. Therefore, this study aimed to show the prevalence of PSTs from commercially available shellfish in Zhejiang Province, China, during the period of frequent red tides, investigate the factors affecting the distribution of PSTs, and assess the risk of PST intake following the consumption of bivalve shellfish among the Zhejiang population.

      • Natural toxins
      • Shellfish toxins
  5. Zearalenone promotes porcine ESCs apoptosis by enhancing Drp1-mediated mitochondrial fragmentation and activating the JNK pathway

    • Food and Chemical Toxicology
    • Zearalenone (ZEA) is widely present in food and feed, and pigs are susceptible to its effects. This study explored the underlying function of ZEA-induced apoptosis in porcine endometrial stromal cells (ESCs) through activation of the JNK signaling pathway and mitochondrial division. This study utilized ESCs to explore the impact of exposure to ZEA. A mitochondrial division inhibitor (Mdivi) was also included as a reference.

      • Natural toxins
      • Mycotoxins
  6. Selectivity of chemical and biological foliar treatments on the phyllosphere communities of bacteria and fungi antagonistic to Fusarium verticillioides in maize

    • Journal of Phytopathology
    • Abstract Maize grain production in the tropics is affected by Fusarium verticillioides, leading to significant losses in yield and quality. Fungicides are commonly used to control foliar diseases and increase grain yield, but have limited efficacy against F. verticillioides and may even stimulate the fungus to produce mycotoxins. Biocontrol can reduce F.

      • Natural toxins
      • Mycotoxins
  7. Oxidative Stress and DNA Damage in Pagrus major by the Dinoflagellate Karenia mikimotoi

    • Toxins
    • Karenia mikimotoi is a common species of red tide dinoflagellate that causes the mass mortality of marine fauna in coastal waters of Republic of Korea. Despite continuous studies on the ecophysiology and toxicity of K. mikimotoi, the underlying molecular mechanisms remain poorly understood. Red sea bream, Pagrus major, is a high-value aquaculture fish species, and the coastal aquaculture industry of red sea bream has been increasingly affected by red tides.

      • Natural toxins
      • Shellfish toxins
  8. Unraveling the combined deleterious effects of ochratoxin a and atrazine upon broiler’s health: Toxicopathological, serum biochemical and immunological perspectives

    • Toxicon
    • Atrazine, a herbicide, is used for eradication of broad-leaved herbs in corn crop; and ochratoxins, particularly ochratoxin A (OTA), are major pollutants of poultry diet. Existence of both of these hazardous chemicals as residues is obvious as elucidated by various epidemiological findings. The present study was designed to investigate toxicopathological, serum biochemical and immunological alterations incurred by atrazine alone and/or, in combination with OTA in broilers.

      • Natural toxins
      • Mycotoxins
  9. Aflatoxin detoxification by thermal cooking treatment and evaluation of in vitro bioaccessibility from white and brown rice

    • Food Chemistry
    • Aflatoxins pose a severe risk to the human health. In this study, the detoxifying capacity of a thermal cooking treatment applied to white and brown rice spiked with aflatoxins B1, B2, G1 and G2 as well as the aflatoxin bioaccessibility in cooked rice after applying an in vitro digestion model was evaluated.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Smart-seq2 Technology Reveals a Novel Mechanism That Zearalenone Inhibits the In Vitro Maturation of Ovine Oocytes by Influencing TNFAIP6 Expression

    • Toxins
    • Zearalenone (ZEN), a non-steroidal estrogenic fungal toxin widely present in forage, food, and their ingredients, poses a serious threat to animal and human reproductive health. ZEN also threatens ovine, a major source of human food and breeding stock. However, the mechanisms underlying the impact of ZEN on the in vitro maturation (IVM) of ovine oocytes remain unclear. This study aimed to elucidate these mechanisms using the Smart-seq2 technology.

      • Natural toxins
      • Mycotoxins
  11. Fate of aflatoxin M1 from milk to typical Italian cheeses: Validation of an HPLC method based on aqueous buffer extraction and immune-affinity clean up with limited use of organic solvents

    • Food Control
    • Aflatoxins are mycotoxins produced by several species of Aspergillus fungi which can be found in food and feed. When lactating animals are exposed to feedstuff contaminated by aflatoxin B1, they can excrete its hydroxylated form, aflatoxin M1 (AFM1), into milk.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Exposure Assessment to Deoxynivalenol of Children over 3 Years Deriving from the Consumption of Processed Wheat-Based Products Produced from a Dedicated Flour

    • Toxins
    • Wheat-based products are largely consumed by children worldwide. Deoxynivalenol (DON) is known for its acute and chronic toxicity and is the most common contaminant of cereal grains. Since no legal limits are set for DON in wheat-based products and specific foods intended for children over 3 years on the market, a high risk of overexposure to this contaminant may emerge.

      • Natural toxins
      • Mycotoxins
  13. IoT for Monitoring Fungal Growth and Ochratoxin A Development in Grapes Solar Drying in Tunnel and in Open Air

    • Toxins
    • Optimisation of solar drying to reduce fungal growth and Ochratoxin A (OTA) contamination is a crucial concern in raisin and currant production. Stochastic and deterministic analysis has been utilized to investigate environmental indicators and drying characteristics. The analysis was performed using two seedless grape varieties (Crimson—red and Thompson—white) that were artificially inoculated with Aspergillus carbonarius during open-air and tunnel drying.

      • Natural toxins
      • Mycotoxins
  14. Advancing Mycotoxin Detection: Multivariate Rapid Analysis on Corn Using Surface Enhanced Raman Spectroscopy (SERS)

    • Toxins
    • Mycotoxin contamination on food and feed can have deleterious effect on human and animal health. Agricultural crops may contain one or more mycotoxin compounds; therefore, a good multiplex detection method is desirable to ensure food safety. In this study, we developed a rapid method using label-free surface-enhanced Raman spectroscopy (SERS) to simultaneously detect three common types of mycotoxins found on corn, namely aflatoxin B1 (AFB1), zearalenone (ZEN), and ochratoxin A (OTA).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. The Role of Heterocysts in Cyanotoxin Production during Nitrogen Limitation

    • Toxins
    • Cyanobacteria harmful algal blooms (cyanoHABs) can have impacts on human health, aquatic ecosystems, and the economy. Nutrient management is an important mitigation and even remediation strategy. In this work, the paralytic shellfish toxin (PST)-producing Aphanizomenon (Aphan.) flos-aquae (Linnaeus) Ralfs ex Bornet & Flahault (now identified as Aphan. sp.) single filament isolate NH-5 was grown in P-depleted media, N-depleted media, and complete BG-11 media.

      • Natural toxins
      • Shellfish toxins
  16. Saturated brine dissolution and liquid–liquid extraction combined with UPLC–MS/MS for the detection of typical Alternaria toxins in pear paste

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Alternaria can infest pears to produce metabolites, which can contaminate pears and their processed products. Pear paste, one of the most important pear‐based products, is popular among Chinese consumers especially for its cough relieving and phlegm removal properties. Although people are concerned about the risk of Alternaria toxins in many agro‐foods and their products, little is known about the toxins in pear paste.

      • Natural toxins
      • Mycotoxins
  17. A two‐year study on the occurrence and concentration of mycotoxins in corn varieties with different endosperm textures

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Mycotoxin monitoring in cereal grains has great importance in the food and feed industries. This study evaluated mycotoxin contamination in corns with different endosperm textures in 2 years of cultivation. Samples of dent, semi‐dent, flint and semi‐flint corns from field experiments were analyzed by high‐performance liquid chromatography coupled with tandem mass spectrometry (HPLC‐MS/MS).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Aflatoxin B1 and ochratoxin A reduction by Lactobacillus spp. during bread making

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Aflatoxin B1 (AFB1) and ochratoxin A (OTA) are among the most important mycotoxins with common presence in bread and bakery products. Biological detoxification of mould food spoilage and mycotoxin contamination by lactic acid bacteria (LABs) exhibits high potential on a cost‐effective and large scale.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  19. Multi-locus genome-wide association studies reveal the genetic architecture of Fusarium head blight resistance in durum wheat

    • Frontiers in Plant Science
    • Durum wheat is more susceptible to Fusarium head blight (FHB) than other types or classes of wheat. The disease is one of the most devastating in wheat; it reduces yield and end-use quality and contaminates the grain with fungal mycotoxins such as deoxynivalenol (DON).

      • Natural toxins
      • Mycotoxins
  20. An immediate and antibody protected carboxyl quantum dot immunochromatographic analysis hierarchical signal amplification test strip based on biotin-streptavidin system for the detection of aflatoxin B1 in peanuts

    • Journal of Food Composition and Analysis
    • As a relatively mature detection method, the test strip can quickly and sensitively detect the target. We designed an immunochromatographic strip based on biotin-streptavidin system to protect antibody (Ab) activity and achieve signal amplification. The coupling condition of biotin (B) and antibody is relatively mild, which protects the activity of antibody.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Regulated and Emerging Mycotoxins in Bulk Raw Milk: What Is the Human Risk?

    • Toxins
    • Mycotoxins are abiotic hazards whose contamination occurs at the pre- and post-harvest stages of the maize value chain, with animal exposure through contaminated feed leading to their excretion into milk. Currently, only aflatoxin M1 is regulated in milk products.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Detection of aflatoxin contamination in single kernel almonds using multispectral imaging system

    • Journal of Food Composition and Analysis
    • The developed multispectral imaging system was tested in the current study for its detection accuracy of aflatoxin B1 (AFB1) in single kernel almonds.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. Aflatoxin M1 decreases the expression of genes encoding tight junction proteins and influences the intestinal epithelial integrity

    • Mycotoxin Research
    • Aflatoxin M1 (AFM1) is a mycotoxin that is commonly found as a milk contaminant, and its presence in milk has been linked to cytotoxicity. The present study aimed to evaluate the acute cytotoxic effects of AFM1 on intestinal Caco-2 cells.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Effects of Climate Change on Areas Suitable for Maize Cultivation and Aflatoxin Contamination in Europe

    • Toxins
    • The climate is changing in Europe: average temperatures are increasing, and so is the frequency of extreme weather events. Climate change has a severe impact on areas suitable for growing certain crops and on food safety, for example, affecting the occurrence of the aflatoxin contamination of maize.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Curcumin alleviates AFB1-induced nephrotoxicity in ducks: regulating mitochondrial oxidative stress, ferritinophagy, and ferroptosis

    • Mycotoxin Research
    • Aflatoxin B1 (AFB1), an extremely toxic mycotoxin that extensively contaminates feed and food worldwide, poses a major hazard to poultry and human health. Curcumin, a polyphenol derived from turmeric, has attracted great attention due to its wonderful antioxidant properties. Nevertheless, effects of curcumin on the kidneys of ducks exposed to AFB1 remain unclear.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins