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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 1802

  1. Effect of the Combined Compound Probiotics with Glycyrrhinic Acid on Alleviating Cytotoxicity of IPEC-J2 Cells Induced by Multi-Mycotoxins

    • Tue, 09/27/2022 - 04:00
    • Toxins
    • Aflatoxins B1 (AFB1), deoxynivalenol (DON) and zearalenone (ZEA) are the three most prevalent mycotoxins, whose contamination of food and feed is a severe worldwide problem.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Intraspecific Growth and Aflatoxin Inhibition Responses to Atoxigenic Aspergillus flavus: Evidence of Secreted, Inhibitory Substances in Biocontrol

    • Tue, 09/27/2022 - 04:00
    • Phytopathology®
    • The fungus Aspergillus flavus infects corn, peanut, and cottonseed, and contaminates seeds with acutely poisonous and carcinogenic aflatoxin. Aflatoxin contamination is a perennial threat in tropical and subtropical climates. Nonaflatoxin-producing isolates (atoxigenic) are deployed in fields to mitigate aflatoxin contamination. The biocontrol competitively excludes toxigenic A. flavus via direct replacement and thigmoregulated (touch) toxin inhibition mechanisms.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  3. An Aflatoxin-M1 biochip using graphene quantum dot-gold hybrid nanoparticles

    • Sun, 09/25/2022 - 04:00
    • Food Chemistry
    • Toxicosis through food and feed has remained a point of concern to food sectors across the globe. Although strict regulations have been implemented in developed and developing countries, their detection in food matrices is an evolving science. This study focuses on the development and fabrication of an electrochemical microfluidic biosensor that deploys aptamers to detect trace concentrations of Aflatoxin-M1 (AF-M1) in milk samples.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Effects of Compound Mycotoxin Detoxifier on Alleviating Aflatoxin B1-Induced Inflammatory Responses in Intestine, Liver and Kidney of Broilers

    • Sun, 09/25/2022 - 04:00
    • Toxins
    • In order to alleviate the toxic effects of aflatoxins B1 (AFB1) on inflammatory responses in the intestine, liver, and kidney of broilers, the aflatoxin B1-degrading enzyme, montmorillonite, and compound probiotics were selected and combined to make a triple-action compound mycotoxin detoxifier (CMD). The feeding experiment was divided into two stages.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  5. High speed homogenization assisted encapsulation of synergistic essential oils formulation: Characterization, in vitro release study, safety profile, and efficacy towards mitigation of aflatoxin B1 induced deterioration in rice samples

    • Sun, 09/25/2022 - 04:00
    • Food and Chemical Toxicology
    • Application of essential oils to mitigate aflatoxin B1 (AFB1) contamination in food is a current research hotspot; however, their direct incorporation may cause toxic effects, and changes in food organoleptic properties.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  6. Prediction of Aspergillus parasiticus inhibition and aflatoxin mitigation in red pepper flakes treated by pulsed electric field treatment using machine learning and neural networks

    • Sat, 09/24/2022 - 04:00
    • Food Research International
    • Presence of aflatoxins in agricultural products is a worldwide problem. Because of their high heat stability and resistance to most of the food processing technologies, aflatoxin degradation is still a big challenge.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  7. Inhibition of Essential Oils on Growth of Aspergillus flavus and Aflatoxin B1 Production in Broth and Poultry Feed

    • Fri, 09/23/2022 - 04:00
    • Toxins
    • Aflatoxin B1 (AFB1), a common contaminant in food and feed during storage, does great harm to human and animal health. Five essential oils (thymol, carvacrol, cinnamaldehyde, eugenol, and citral) were tested for their inhibition effect against Aspergillus flavus (A. flavus) in broth and feed. Cinnamaldehyde and citral were proven to be most effective against A. flavus compared to others and have a synergistic effect when used simultaneously.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  8. Development and Validation of LC-Q-TOF-MS Methodology to Determine Mycotoxin Biomarkers in Human Urine

    • Wed, 09/21/2022 - 04:00
    • Toxins
    • Mycotoxin contamination of foodstuffs is a health concern worldwide and monitoring human exposure to mycotoxins is a key concern. Most mycotoxins and their metabolites are excreted in urine, but a reliable detection method is required, considering the low levels present in this biological sample.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. A stem-loop like aptasensor for sensitive detection of aflatoxin based on graphene oxide/AuNPs nanocomposite platform

    • Tue, 09/20/2022 - 04:00
    • Food Chemistry
    • Aflatoxin as the potent carcinogenic mycotoxin had been received great attention for detection in food industry and safety. Due to low quantity of aflatoxin in food samples, there is a need to develop a sensitive method toward its detection. In the present study, an aflatoxin B1 (AFB1) specific aptasensor with internal complementary sequence was developed for detection of AFB1.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  10. Mycotoxins Contamination in Rice: Analytical Methods, Occurrence and Detoxification Strategies

    • Tue, 09/20/2022 - 04:00
    • Toxins
    • The prevalence of mycotoxins in the environment is associated with potential crop contamination, which results in an unavoidable increase in human exposure. Rice, being the second most consumed cereal worldwide, constitutes an important source of potential contamination by mycotoxins.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  11. Variation of Aflatoxin Levels in Stored Edible Seed and Oil Samples and Risk Assessment in the Local Population

    • Sun, 09/18/2022 - 04:00
    • Toxins
    • Five hundred and twenty samples of edible seeds and oilseeds (sunflower, palm, peanut, sesame, cotton, and grapeseed) were purchased from markets, farmers, and superstores in the central cities of Punjab, Pakistan. A total of 125 (48.1%) edible seed samples from a 6 ≤ months storage period, and 127 (48.8%) from a 2 ≥ years storage period were found to be infested with AFs.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Effect of environmental factors on the aflatoxin production by Aspergillus flavus during storage in upland rice seed using response surface methodology

    • Sat, 09/17/2022 - 04:00
    • LWT
    • The purpose of this study was to predict the optimal storage conditions for inhibiting aflatoxin production in upland rice seeds inoculated with Aspergillus flavus. The effects of storage conditions including moisture (A), temperature (B) and incubation time (C) on aflatoxin (AFG1, AFG2, AFB1, AFB2 and AFTOT) production in upland rice seed after inoculation of A.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  13. A new probiotic Lactobacillus plantarum strain isolated from traditional dairy together with nanochitosan particles shows the synergistic effect on aflatoxin B1 detoxification

    • Sat, 09/17/2022 - 04:00
    • Archives of Microbiology
    • The present study aimed to evaluate the effects of new Lactobacillus plantarum strain isolated from dairy products as well as chitosan nanoparticles on reducing aflatoxin B1 (AFB1) toxicity In vitro. After collection and preparation of yogurt, cheese, milk, and whey products, lactic acid bacteria (LABs) were isolated and identified using biochemical and molecular methods. pH, bile, and salt tolerance tests were used to measure probiotic activity.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  14. Quantitative PCR (qPCR) Reveals that the Aflatoxin-Free Pistachio Samples Can Be Potentially Contaminated with Fungal Materials

    • Sat, 09/17/2022 - 04:00
    • Food Analytical Methods
    • Aflatoxins (AF) are the most potent group of mycotoxins that are produced by certain ascomycete fungi. These toxins can contaminate a large board of food commodities, thus causing a severe toxicity in animals and humans. The detection of fungal contamination of food is still challenging. This work determines whether an accurate relationship between the contamination of nut samples with AF and their contamination with fungal genomic DNA could be established.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  15. Formulation of Aflatoxins B1 & B2 reduction in corn by low level gamma irradiation

    • Sat, 09/17/2022 - 04:00
    • Toxicon
    • Corn is one of the main food items for humans and animals. Contamination of corn with aflatoxin during harvest, storage, and transport is one of the human problems. Different methods for removing and inactivating aflatoxin in corn have been introduced so far.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. Interaction study of aflatoxin M1 with milk proteins using ATR-FTIR

    • Fri, 09/16/2022 - 04:00
    • Journal of Food Science and Technology
    • Aflatoxin M1 (AFM1) is a metabolite of carcinogenic aflatoxin B1 (AFB1) and appears in milk of dairy animals on ingestion of feed contaminated with AFB1. It has been reported to have affinity towards milk proteins, the exact mechanism of which is still unknown. In the present study, ATR-FTIR coupled with chemometrics is utilized to understand AFM1 interaction with milk proteins.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  17. Plant-based natural flavonoids show strong inhibition of aflatoxin production and related gene expressions correlated with chemical structure

    • Fri, 09/16/2022 - 04:00
    • Food Microbiology
    • Aflatoxins are strong carcinogenic and mutagenic fungal metabolites, and aflatoxin contamination is a critical issue in agriculture and food production. Natural flavonoids can suppress aflatoxin biosynthesis; however, the structure–activity relationship remains unclear.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. Mechanisms and transformed products of aflatoxin B1 degradation under multiple treatments: a review

    • Thu, 09/15/2022 - 04:00
    • Critical Reviews in Food Science and Nutrition
    • Aflatoxins, including aflatoxin B1, B2, G1, G2, M1, and M2, are one of the major types of mycotoxins that endangers food safety, human health, and contribute to the immeasurable loss of food and agricultural production in the world yearly. In addition, aflatoxin B1 (AFB1) mainly produced by Aspergilus sp. is the most potent of these compounds and has been well documented to cause the development of hepatocellular carcinoma in humans and animals. This paper reviewed the detoxification

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  19. Characterization of a Trametes versicolor aflatoxin B1-degrading enzyme (TV-AFB1D) and its application in the AFB1 degradation of contaminated rice in situ

    • Wed, 09/14/2022 - 04:00
    • Frontiers in Microbiology
    • Aflatoxin B1 (AFB1) contaminates rice during harvest or storage and causes a considerable risk to human and animal health. In this study, Trametes versicolor AFB1–degrading enzyme (TV–AFB1D) gene recombinantly expressed in engineered E. coli BL21 (DE3) and Saccharomyces cerevisiae. The TV–AFB1D enzymatic characteristics and AFB1 degradation efficiency in contaminated rice were investigated. Results showed that the size of recombinant TV-AFB1D expressing in E. coli BL21 (DE3) and S.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Prevalence of Aflatoxin Contamination in Peanuts and Peanut Butter from an Informal Market, Harare, Zimbabwe

    • Wed, 09/14/2022 - 04:00
    • International Journal of Food Science
    • Peanuts and peanut butter play an important role nutritionally in improving the diets of individuals in many parts of Africa, especially in the fight against child malnutrition. However, in developing countries such as Zimbabwe, most of the raw peanuts and peanut butter produced in backyard industries are sold in informal markets and rarely undergo formal safety inspection for aflatoxin contamination.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Degradation of Aflatoxin B1 by recombinant laccase extracellular produced from Escherichia coli

    • Wed, 09/14/2022 - 04:00
    • Ecotoxicology and Environmental Safety
    • Bioenzymatic degradation of aflatoxin B1 (AFB1) is a safe, efficient and environmentally friendly detoxification technology.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  22. Immunoaffinity Cleanup and Isotope Dilution-Based Liquid Chromatography Tandem Mass Spectrometry for the Determination of Six Major Mycotoxins in Feed and Feedstuff

    • Mon, 09/12/2022 - 04:00
    • Toxins
    • In this study, a liquid chromatography-tandem mass spectrometry (LC-MS/MS) method for simultaneous determination of deoxynivalenol, aflatoxin B1, zearalenone, ochratoxin A, T-2 toxin and fumonisin B1 in feed and feedstuff was established.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. Progress on the detoxification of aflatoxin B1 using natural anti-oxidants

    • Sun, 09/11/2022 - 04:00
    • Food and Chemical Toxicology
    • Aflatoxins are toxic secondary metabolites produced by Aspergillus fungi. The most toxic among them is Aflatoxin B1 (AFB1) which is known to have genotoxic, immunotoxic, teratogenic, carcinogenic, and mutagenic toxic effects (amongst others). The mechanisms responsible for its toxicity include the induction of oxidative stress, cytotoxicity, and DNAdamage.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  24. Reduction of Aspergillus flavus and aflatoxin on almond kernels using gaseous chlorine dioxide fumigation

    • Sat, 09/10/2022 - 04:00
    • Food Chemistry
    • The almond industry suffers product losses caused by mold growth and toxin contamination. Gaseous chlorine dioxide (ClO2) has the potential for postharvest reduction of mycotoxic Aspergillus flavus. In this study, almonds inoculated with A. flavus were fumigated with gaseous ClO2 for 1, 2, 3, 8, 12, and 24 h using a dry precursor sachet batch method. The headspace concentration ranged from 0.5-2.4 mg/L, depending on initial dosing and time.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Protective Effect of SeMet on Liver Injury Induced by Ochratoxin A in Rabbits

    • Fri, 09/09/2022 - 04:00
    • Toxins
    • Ochratoxin A (OTA) is second only to aflatoxin in toxicity among mycotoxins. Recent studies have shown that selenomethionine (SeMet) has a protective effect on mycotoxin-induced toxicity. The purpose of this study was to investigate the protective effect and mechanism of SeMet on OTA-induced liver injury in rabbits.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins