Research Publications (Food Safety)

Yanghe decoction is a traditional Chinese medicine prescription and has been used for breast cancer treatment for many years. However, the effective ingredients in the decoction have not been identified. The expression of poly (ADP‐ribose) polymerase‐1 is highly related to breast cancer. Using poly (ADP‐ribose) polymerase‐1 as a probe, we expressed the haloalkane dehalogenase‐tagged protein in E.

With metabolism being one of the main routes of drug elimination from the body (accounting for removal of around 75% of known drugs), it is crucial to understand and study metabolic stability of drug candidates. Metabolically unstable compounds are uncomfortable to administer (requiring repetitive dosage during therapy), while overly‐stable drugs increase risk of adverse drug reactions.

Priority pollutants chlorophenols are broadly used chemicals that are persistent in the environment and causing serious human health hazards. The current study introduces a novel adsorbent for the extraction of chlorophenols from river water, surface water, and milk by headspace solid phase microextraction coupled with GC.

Variation in inter‐human attractiveness to mosquitoes, and the preference of mosquitoes to bite certain regions on the human host, are possible avenues for identifying lead compounds as potential mosquito attractants or repellents.

A green and efficient sample preparation method using a deep eutectic solvent‐based ultrasounds‐assisted dispersive liquid–liquid microextraction with solidification of the aqueous phase followed by HPLC analysis was developed for preconcentration and determination of heavy metals in environmental samples.

Despite substantial developments of extraction and separation techniques, isolation of natural products from natural sources is still a challenging task. Undoubtedly hybrid methods like LC‐NMR or LC‐MS made on‐line structure elucidation possible and provided impressive examples of natural product identification without prior isolation, however, in many cases the necessity to get the purified compounds in hand is still a fact.

Driven by the significant need for characterization of the chemical speciation of arsenic in food, this work developed a method for rapid determination of four common arsenic species, namely, arsenite, arsenate, monomethyl arsenic acid, and dimethyl arsenic acid, in vegetables using microwave‐assisted extraction, followed by detection with high‐performance liquid chromatography hyphenated to inductively coupled plasma‐mass spectrometry.

Here, a two‐stage column separation scheme is developed for the concomitant isolation of Sr, Pb, Nd, and Hf from geological samples. The first column, which consists of three resin layers (AG50W‐X8 ion exchange resin + Ln specific resin + Sr specific resin), separates the high field strength element + rare earth element, Sr and Pb from the matrices.