An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 26 - 50 of 2804

  1. Vitamin C and/or garlic can antagonize the toxic effects of cadmium on growth performance, hematological, and immunological parameters of growing Japanese quail

    • Poultry Science
    • This study used 300 1-day-old, sexless, developing chicks of Japanese quail to estimate the ability of vitamin C and/or garlic to antagonize the venomous influence of cadmium (Cd) on the hematological, immunological, and performance characteristics of developing Japanese quail. The quail was separated into 5 similar groups of 60 chicks apiece, and 6 duplicates (10 each) were given to each sub-group. The control group received a basal diet without any supplements.

      • Chemical contaminants
      • Heavy Metals
  2. Simultaneous quantification of tin and lead species in Antarctic krill and fish by interfacing high-performance liquid chromatography with inductively coupled plasma mass spectrometry based on strong cation-exchange and Amphion columns

    • Food Chemistry
    • Tin and lead are a global concern considering their species-dependent toxicity, bioavailability and transformation. Simultaneous speciation analysis of tin and lead is challenging for a large food capacity containing unstable species. Herein, we developed two sensitive methods for rapid quantification of tin and lead species in Antarctic seafood by high-performance liquid chromatography and inductively coupled plasma mass spectrometry based on strong cation-exchange and Amphion columns.

      • Chemical contaminants
      • Heavy Metals
  3. Nanotechnology in Sustainable Agriculture: A Double‐Edged Sword

    • Journal of the Science of Food and Agriculture
    • Abstract Nanotechnology is a rapidly developing discipline that has the potential to transform the way we approach problems in a variety of fields, including agriculture. The utilization of nanotechnology in sustainable agriculture has gained popularity in recent years.

      • Chemical contaminants
      • Heavy Metals
  4. From inflammation to pyroptosis: Understanding the consequences of cadmium exposure in chicken liver cells

    • Ecotoxicology and Environmental Safety
    • Hepatotoxicity is frequently observed following acute cadmium (Cd) exposure in chicken. Oxidative stress and subsequent inflammation are regarded as the main reasons for cadmium-induced liver injury. NOD-like receptor (NLR) family pyrin domain-containing 3 (NLRP3) inflammasome-induced pyroptosis is involved in various inflammatory diseases, including liver injury.

      • Chemical contaminants
      • Heavy Metals
  5. Fetoplacental disposition and toxicity of cadmium in mice lacking the Bcrp transporter

    • Toxicological Sciences
    • The environmental toxicant cadmium (Cd) impairs the growth of rodents and humans in utero which in turn heightens susceptibility to diseases later in life. We previously demonstrated that the maternal-facing efflux transporter, breast cancer resistance protein (human BCRP/ABCG2, mouse Bcrp/Abcg2) confers resistance against Cd toxicity in human trophoblasts.

      • Chemical contaminants
      • Heavy Metals
  6. Three-Dimensional (3D) Imprinting Polymer Based on Graphene Oxide-Mesoporous Silica Nanobeads for chemometrics-assisted micro solid-phase extraction of Lead in fish samples.

    • Journal of Food Composition and Analysis
    • A rapid, sensitive, accurate and precise micro solid phase extraction method for the determination of Pb (II) in Fish sample by ionic imprinted polymer was developed on the surface of mesoporous silica and based on graphene oxide nanobeads. Extraction parameters were optimized using Box-Behnken design to achieve the twin objectives of quantitative determination and removal of Pb (II).

      • Chemical contaminants
      • Heavy Metals
  7. In vitro bioavailability assessment of arsenic species from seafood: influence of the culinary treatments in dietary intake

    • Journal of Food Composition and Analysis
    • Despite the nutritional importance of seafood, these marine organisms can bioaccumulate environmentally persistent and potentially toxic chemicals, such as arsenic (As) and its species. In this work, the influence of culinary treatments commonly performed before seafood consumption on the bioavailability of As and As species was evaluated.

      • Chemical contaminants
      • Heavy Metals
  8. Probabilistic risk assessment for determining nonessential metals in commercial infant formula products in Taiwan

    • Journal of Food Science
    • Abstract During the early months of life, infant formula plays a crucial role as a primary source of both food and essential nutrients for infants, serving as a replacement for or supplement to breast milk. However, nonessential metals in infant formulas are a concern because infants are highly vulnerable to chemical exposure. The aim of this study was to investigate infant exposure to nonessential metals in infant formula products in Taiwan and assess the associated health risks.

      • Chemical contaminants
      • Heavy Metals
  9. Poison in the water: Arsenic's silent assault on fish health

    • Journal of Applied Toxicology
    • Abstract Arsenic occurs across the world in freshwater and marine environments, menacing the survival of aquatic organisms. Organic and inorganic forms of this substance can be found, in which the inorganic form is more hazardous than the organic form. Most aquatic bodies contain inorganic arsenic species, but organic species are believed to be the dominant form of arsenic in the majority of fish. Natural and anthropogenic both are the sources of water contamination with arsenic.

      • Chemical contaminants
      • Heavy Metals
  10. Levilactobacillus brevis MZ384011 and  Levilactobacillus brevis MW362779 can mitigate lead induced hepato-renal damage by regulating visceral dispersion and fecal excretion

    • World Journal of Microbiology and Biotechnology
    • Heavy metal pollution is a global issue. Current study provides evidence on Pb toxicity ameliorative potential and safe nature of Levilactobacillus brevis MZ384011 (S1) and Levilactobacillus brevis MW362779 (S2), isolated from carnivore gut and human milk, respectively. In a 60-days experiment, the rats were distributed into six groups.

      • Chemical contaminants
      • Heavy Metals
  11. Trophic Transfer of Cd, Cu, Pb, Zn, P and Se in Dutch Storage Water Reservoirs

    • Archives of Environmental Contamination and Toxicology
    • Heavy metals are naturally omnipresent in aquatic systems. Excess amounts of heavy metals can accumulate in organisms of pollution impacted systems and transfer across a food web. Analysing the food web structure and metal contents of the organisms can help unravel the pathways of biomagnification or biodilution and gain insight in trophic linkages.

      • Chemical contaminants
      • Heavy Metals
  12. Enhancing Cadmium Stress Tolerance in Potato Plants Through Overexpression of the VvWRKY2 Transcription Factor

    • Potato Research
    • WRKY transcription factors (TF) are identified as important regulating plant proteins involved in stress response signaling pathways. Overexpression of these transcription factors in plants improved plant biotic and abiotic stress responses. In this context, we have envisaged transferring a cDNA encoding the grapevine VvWRKY2TF in potato plants. Four transgenic lines were selected (BFW2A, BFW2C, BFW2D, and BFW2F).

      • Chemical contaminants
      • Heavy Metals
  13. Update of the risk assessment of inorganic arsenic in food

    • EFSA Journal
    • Abstract The European Commission asked EFSA to update its 2009 risk assessment on arsenic in food carrying out a hazard assessment of inorganic arsenic (iAs) and using the revised exposure assessment issued by EFSA in 2021. Epidemiological studies show that the chronic intake of iAs via diet and/or drinking water is associated with increased risk of several adverse outcomes including cancers of the skin, bladder and lung.

      • Chemical contaminants
      • Heavy Metals
  14. Plasticity of parental CENH3 incorporation into the centromeres in wheat × barley F1 hybrids

    • Frontiers in Plant Science
    • Incorporating the centromere-specific histone H3 protein CENH3 into the centromeric nucleosomes is indispensable for accurate centromere function and balanced chromosome segregation in most eukaryotes, including higher plants. In the cell nuclei of interspecific hybrids, divergent centromeric DNAs cohabit and lead the corresponding parental chromosomes through the mitotic and meiotic cell divisions.

      • Chemical contaminants
      • Heavy Metals
  15. Developmental effects of zebrafish (Danio rerio) embryos after exposure to glyphosate and lead mixtures

    • Ecotoxicology and Environmental Safety
    • Natural aquatic environments have a heterogeneous composition; therefore, simultaneous exposure to multiple contaminants is relevant and more realistic when assessing exposure and toxicity.

      • Chemical contaminants
      • Heavy Metals
  16. Metabolite‐based genome‐wide association studies enable the dissection of the genetic bases of flavonoids, betaine and spermidine in wolfberry (Lycium)

    • Plant Biotechnology Journal
    • Summary Wolfberry is a plant with medicinal and food values. However, its bioactive ingredients and the corresponding genetic bases have not been determined. Here, we de novo generated a chromosome‐level genome assembly for wolfberry, yielding a genome sequence of ~1.77 Gb with contig N50 of 50.55 Mb and 39 224 predicted gene models. A variation map, using 307 re‐sequenced accessions, was called based on this genome assembly.

      • Chemical contaminants
      • Heavy Metals
  17. Metagenomic and proteomic insights into the self‐adaptive cell surface hydrophobicity of Sphingomonas sp. strain PAH02 reducing the migration of cadmium‐phenanthrene co‐pollutant in rice

    • Environmental Microbiology
    • Our research results have revealed the molecular mechanisms and processes of how the dominant bacterial community in paddy soils, represented by Sphingomonas sp. strain PAH02, responds to the co‐pollution of heavy metals and polycyclic aromatic hydrocarbons through self‐adaptive cell surface hydrophobicity. We identified key responsive genes and proteins and emphasized that strain PAH02 is a shared core of the microbial community and participates in biogeochemical cycles in paddy soils.

      • Chemical contaminants
      • Heavy Metals
  18. Toxic effects of nanopolystyrene and cadmium on the intestinal tract of the Chinese mitten crab (Eriocheir sinensis)

    • Ecotoxicology and Environmental Safety
    • Nanopolystyrene (NP) and cadmium (Cd) are ubiquitous contaminants in aquatic systems. The present study aimed to investigate the toxic effects of exposure to ambient concentrations of NP and/or Cd on the intestinal tract of the Chinese mitten crab (Eriocheir sinensis).

      • Chemical contaminants
      • Heavy Metals
  19. Potential effect dietary supplementation of calcium tetraborate in quails exposed to cadmium: Its impact on productive performance, oxidative stress, cecal microflora, and histopathological changes

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is a ubiquitous environmental pollutant, and Cd exposure harms human health, agriculture, and animal husbandry.

      • Chemical contaminants
      • Heavy Metals
  20. Modulations of functional traits of Spinacia oleracea plants exposed to cadmium stress by using H2S as an antidote: a regulatory mechanism

    • Physiology and Molecular Biology of Plants
    • The present study is based on the application of H2S as an exogenous antidote in Spinacia oleracea (spinach) plants grown in Cd-contaminated (50 ppm) soil. The different doses of H2S in the form of NaHS (10, 50, 100, 200, and 500 μM) have been applied as a foliar spray to regulate the physiological attributes under Cd toxicity.

      • Chemical contaminants
      • Heavy Metals
  21. Ecotoxicology of Trace Elements in European Oyster (Ostrea edulis), Seawater, and Sedimentsacross Boston Harbor, Massachusetts,USA

    • Bulletin of Environmental Contamination and Toxicology
    • European oyster (Ostrea edulis) can be used for biological monitoring of water and sediment quality and serve as a conduit of trace elements to humans via consumption. Trace element concentrations in seawater, sediment, O. edulis edible tissues and shells from Boston Harbor were studied and found to be elevated relative to comparative studies in native ecosystems in the Adriatic Sea and Bay of Biscay.

      • Chemical contaminants
      • Heavy Metals
  22. Pressmud Subdue Phytoremediation Indices in Lead-Contaminated Soils: A Human Health Perspective

    • Bulletin of Environmental Contamination and Toxicology
    • Direct discharge of waste into water bodies and mining are two major sources of lead contamination in ecosystems. Water scarcity promoted the usage of industrial effluent-contaminated waters for crop production, mainly in peri-urban areas. These wastewaters may contain heavy metals and pollute crop ecosystems. These metals can reach the living cell via contaminated raw foodstuffs that grow under these conditions and cause various ill effects in metabolic activities.

      • Chemical contaminants
      • Heavy Metals
  23. Conservation and health policy implications linked to the human consumption of sea turtles in northwestern Mexico

    • World Medical & Health Policy
    • Abstract Human consumption of sea turtles remains prevalent throughout Mexico even though laws restricting trade and take of threatened and endangered species have been in place for several decades. The illegal consumption of sea turtles represents a risk to animal conservation, and the pathogens in the meat can adversely affect human health.

      • Chemical contaminants
      • Heavy Metals
  24. Astilbin antagonizes developmental cardiotoxicity after cadmium exposure in chicken embryos by inhibiting endoplasmic reticulum stress and maintaining calcium homeostasis

    • Ecotoxicology and Environmental Safety
    • Cadmium (Cd) is a dangerous heavy metal with high toxicity that is known to impair development. Astilbin (ASB) is a protective flavonoid compound. We aimed to explore whether ASB can antagonize the myocardial developmental toxicity of Cd exposure. Cd (2 µg) and/or ASB (0.002 µg) were injected into embryonized eggs that were 1 day old.

      • Chemical contaminants
      • Heavy Metals
  25. Epigenome-wide perspective of cadmium-associated DNA methylation and its mediation role in the associations of cadmium with lipid levels and dyslipidemia risk

    • Food and Chemical Toxicology
    • Background 

      Studies demonstrated the associations of cadmium (Cd) with lipid levels and dyslipidemia risk, but the mechanisms involved need further exploration.

      Objectives

      • Chemical contaminants
      • Heavy Metals