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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 101 - 125 of 2804

  1. Multiplex metabolic pathway engineering of Monascus pilosus enhances lovastatin production

    • Applied Microbiology and Biotechnology
    • Monascus sp. is an important food microbial resource with the production of cholesterol-lowering agent lovastatin and other healthy metabolites. However, the mycotoxin citrinin naturally produced by Monascus sp. and the insufficient productivity of lovastatin limit its large-scale use in food industry.

      • Chemical contaminants
      • Heavy Metals
      • Natural toxins
      • Mycotoxins
  2. Cadmium-109 Internal Kinetics in Diamond Sturgeon Acipenser gueldenstaedtii are Strongly Influenced by Salinity, Exposure Pathway and History

    • Archives of Environmental Contamination and Toxicology
    • Cadmium-109 whole-body and internal biokinetics were experimentally investigated in critically endangered diamond sturgeon Acipenser gueldenstaedtii after uptake from water or food, in fresh (FW) and brackish (BW; 9‰) salinities typical of the Caspian Sea. Whole-body rates of uptake of 109Cd from water and subsequent depuration were quantified over 14 and 28 days, respectively.

      • Chemical contaminants
      • Heavy Metals
  3. Environmentally relevant lead alters nuclear integrity in erythrocytes and generates oxidative stress in liver of Anabas testudineus: Involvement of Nrf2‐Keap1 regulation and expression of biomarker genes

    • Journal of Applied Toxicology
    • Abstract Genotoxic and hepatotoxic effects of lead (Pb) on a freshwater fish, climbing perch (Anabas testudineus) were studied at an environmentally relevant concentration (43.3 ppm). The genotoxic potential of Pb was confirmed by micronucleus study, with increased frequencies of erythrocytic nuclear alterations like lobed, blebbed, notched, fragmented, and micronuclei were observed in erythrocytes in treated groups as compared to control.

      • Chemical contaminants
      • Heavy Metals
  4. Assessment of Joint Toxicity of Arsenate and Lead by Multiple Endpoints in Chlamydomonas reinhardtii

    • Bulletin of Environmental Contamination and Toxicology
    • In aquatic ecosystems, arsenate (As(V)) and lead (Pb(II)) frequently coexist but their joint toxicity on microalgae remains unknown. In this study, Chlamydomonas reinhardtii was exposed to various levels of combined As(V) and Pb(II) treatments. The cell growth, respiration, pigment synthesis, polysaccharides and protein secretion as well as As speciation of C. reinhardtii were analyzed.

      • Chemical contaminants
      • Heavy Metals
  5. Exogenous application of glutathione enhanced growth, nutritional orchestration and physiochemical characteristics of Brassica oleracea L. under lead stress

    • Physiology and Molecular Biology of Plants
    • A major obstacle to agricultural production and yield quality is heavy metal contamination of the soil and water, which leads to lower productivity and quality of crops. The situation has significantly worsened as a result of the growing population and subsequent rise in food consumption. The growth of nutrient-rich plants is hampered by lead (Pb) toxicity in the soil. Brassica oleracea L.

      • Chemical contaminants
      • Heavy Metals
  6. WheatSpikeNet: an improved wheat spike segmentation model for accurate estimation from field imaging

    • Frontiers in Plant Science
    • Phenotyping is used in plant breeding to identify genotypes with desirable characteristics, such as drought tolerance, disease resistance, and high-yield potentials. It may also be used to evaluate the effect of environmental circumstances, such as drought, heat, and salt, on plant growth and development. Wheat spike density measure is one of the most important agronomic factors relating to wheat phenotyping.

      • Chemical contaminants
      • Heavy Metals
  7. Comparative efficacy of silicon and iron oxide nanoparticles towards improving the plant growth and mitigating arsenic toxicity in wheat (Triticum aestivum L.)

    • Ecotoxicology and Environmental Safety
    • Nano-enabled agriculture has emerged as an attractive approach for facilitating soil pollution mitigation and enhancing crop production and nutrition. In this study, we conducted a greenhouse experiment to explore the efficacy of silicon oxide nanoparticles (SiONPs) and iron oxide nanoparticles (FeONPs) in alleviating arsenic (As) toxicity in wheat (Triticum aestivum L.) and elucidated the underlying mechanisms involved.

      • Chemical contaminants
      • Heavy Metals
  8. Assessment of Lactobacillus rhamnosus mediated protection against arsenic-induced toxicity in zebrafish: a qPCR-based analysis of Firmicutes and Bacteroidetes groups and embryonic development

    • Archives of Microbiology
    • Arsenic poses a significant health risk worldwide, impacting the gut microbiota, reproductive health, and development. To address this issue, a cost-effective method like probiotic supplementation could be beneficial. However, the interplay between arsenic toxicity, probiotics, gut microbiota, and maternal transcript modulation remains unexplored. This study investigates the impact of Lactobacillus rhamnosus (L.

      • Chemical contaminants
      • Heavy Metals
  9. Iron-modified biochar improves plant physiology, soil nutritional status and mitigates Pb and Cd-hazard in wheat (Triticum aestivum L.)

    • Frontiers in Plant Science
    • Environmental quality and food safety is threatened by contamination of lead (Pb) and cadmium (Cd) heavy metals in agricultural soils. Therefore, it is necessary to develop effective techniques for remediation of such soils. In this study, we prepared iron-modified biochar (Fe-BC) which combines the unique characteristics of pristine biochar (BC) and iron.

      • Chemical contaminants
      • Heavy Metals
      • Produce Safety
      • Post Harvest
  10. Assessment of the feed additive consisting of alpha‐galactosidase produced by Saccharomyces cerevisiae CBS 615.94 and endo‐1,4‐beta‐glucanase produced by Aspergillus niger CBS 120604 (Agal‐Pro BL/BL‐L®) for use in chickens for fattening, minor poultry spe

    • EFSA Journal
    • Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the assessment of the application for renewal of Agal‐Pro BL/BL‐L®. The additive is a preparation of alpha‐galactosidase produced by a genetically modified strain of Saccharomyces cerevisiae (CBS 615.94) and endo‐1,4‐beta‐glucanase produced by a non‐genetically modified strain of Aspergillus niger (CBS 120604).

      • Chemical contaminants
      • Heavy Metals
  11. Phosphorous-Functionalized Wheat Straw Biochar for the Efficient Removal of Cadmium and Lead in Aqueous Solution

    • Water, Air, & Soil Pollution
    • Biochar is an attractive and environmental friendly heavy metal sorbent, but is full-scale application is usually restricted by the limited sorption sites and surface area. Phosphate groups could strongly complex with heavy metal ions. Therefore, in the present study, phytic acid (PA) modified biochar (P-WBC) was prepared via the hydrolysis carbonization of wheat straw and PA at 300 °C and 700 °C.

      • Chemical contaminants
      • Heavy Metals
  12. Virtual screening analysis of natural flavonoids as trimethylamine (TMA)‐lyase inhibitors for coronary heart disease

    • Journal of Food Biochemistry
    • The TMA/TMAO pathway represents one of many microbe‐dependent pathways that will ultimately be linked to CHD pathogenesis Molecular docking results found that baicalein, fisetin, acacetin, and myricetin in flavonoid aglycones, and baicalin, naringin and hesperidin in flavonoid glycosides had good binding effects on TMA‐lyase, which were the most active and could be used as lead compounds for structural modification.

      • Chemical contaminants
      • Heavy Metals
  13. Design and selection of solar‐powered Peltier‐based cooling neera (coconut sap) collecting system

    • Journal of Food Process Engineering
    • Solar‐operated neera tapping device using Pelteir module as cooling system to collect neera in an effective manner without climbing the tree. Abstract The fresh sap harvested from the unbloomed inflorescence of the adult spadix of coconut tree (Cocus nucifera L.) is known as “neera.” It must be collected below room temperature to prevent naturally occurring fermentation.

      • Chemical contaminants
      • Heavy Metals
  14. Safety and efficacy of a feed additive consisting of endo‐1,4‐β‐xylanase produced by Trichoderma citrinoviride DSM 34663 (Hostazym® X) for use in all poultry species, ornamental birds, all growing Suidae and carp (Huvepharma NV)

    • EFSA Journal
    • Abstract Following a request from the European Commission, the EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP) was asked to deliver a scientific opinion on the safety and efficacy of a feed additive containing endo‐1,4‐β‐xylanase produced by Trichoderma citrinoviride DSM 34663 (Hostazym® X).

      • Chemical contaminants
      • Heavy Metals
  15. Protective potential of thymoquinone against cadmium, arsenic, and lead toxicity: A short review with emphasis on oxidative pathways

    • Journal of Applied Toxicology
    • Abstract Heavy metals are among the most important environmental pollutions used in various industries. Their extensive use has increased human susceptibility to different chronic diseases. Toxic metal exposure, especially cadmium, arsenic, and lead, causes oxidative damages, mitochondrial dysfunction, and genetic and epigenetic modifications.

      • Chemical contaminants
      • Heavy Metals
  16. Identification of genes showing altered DNA methylation and gene expression in the renal proximal tubular cells of rats treated with ochratoxin A for 13 weeks

    • Journal of Applied Toxicology
    • Abstract Ochratoxin A (OTA) is a mycotoxin that causes renal carcinogenicity following the induction of karyomegaly in proximal tubular cells after repeated administration to rats. Here, we performed gene profiling regarding altered DNA methylation and gene expression in the renal tubules focusing on the mechanism of OTA‐induced carcinogenesis.

      • Chemical contaminants
      • Heavy Metals
      • Natural toxins
      • Mycotoxins
  17. Resveratrol protects against cadmium‐induced cerebrum toxicity through modifications of the cytochrome P450 enzyme system in microsomes

    • Journal of the Science of Food and Agriculture
    • Abstract BACKGROUND Cadmium (Cd), known as a vital contaminant in the environment, penetrates the blood–brain barrier and accumulates in the cerebrum. Acute toxicosis of Cd, which leads to lethal cerebral edema, intracellular accumulation and cellular dysfunction, remains to be illuminated with regard to the exact molecular mechanism of cerebral toxicity.

      • Chemical contaminants
      • Heavy Metals
  18. Elevated UV photon fluxes minimally affected cannabinoid concentration in a high-CBD cultivar

    • Frontiers in Plant Science
    • Ultraviolet photons (UV) can damage critical biochemical processes. Plants synthesize photo-protective pigments that absorb UV to minimize damage. Cannabinoids absorb UV, so increased UV has the potential to increase cannabinoid synthesis. Studies in the 1980’s provided some evidence for this hypothesis in low-cannabinoid cultivars, but recent studies did not find an increase in cannabinoid synthesis with increasing UV in high-cannabinoid cultivars.

      • Chemical contaminants
      • Heavy Metals
  19. Foliar application of salicylic acid inhibits the cadmium uptake and accumulation in lettuce (Lactuca sativa L.)

    • Frontiers in Plant Science
    • Introduction

      Salicylic acid (SA) is a multi-functional endogenous phytohormone implicated in the growth, development, and metabolism of many plant species.

      Methods

      This study evaluated the effects of different concentrations of SA (0, 25, 100, 200, and 500 mg/L) on the growth and cadmium (Cd) content of lettuce (Lactuca sativa L.) under Cd stress. The different concentrations of SA treatments were administered through foliar application.

      Results

      • Chemical contaminants
      • Heavy Metals
  20. Analyzing the impacts of cadmium alone and in co-existence with polypropylene microplastics on wheat growth

    • Frontiers in Plant Science
    • Heavy metals typically coexist with microplastics (MPs) in terrestrial ecosystems. Yet, little is known about how the co-existence of heavy metals and MPs affect crops. Therefore, this study aimed to evaluate the impact of cadmium (Cd; 40 mg/L) alone and its co-existence with polypropylene (PP)-MPs (50 and 100 µm) on seed germination, root and shoot growth, seedling dry weight (DW), and antioxidant enzyme activities of wheat.

      • Chemical contaminants
      • Heavy Metals
  21. Climate and soil pH control the reduction of cadmium in rice during 7 years of biannual liming

    • Plant and Soil
    • Background and aims Liming is widely known as a cost-efficient agricultural practice to reduce cadmium (Cd) concentration in rice (Oryza sativa L.) grain (CdR) in the short term.

      • Chemical contaminants
      • Heavy Metals
  22. Cadmium speciation in cacao beans changes during a fermentation-like incubation

    • Food Chemistry
    • Cadmium (Cd) concentrations in cacao often exceed food limits. Recently, it was shown that cacao bean fermentation enhances Cd solubility, opening potential for Cd mitigation in cacao products. This study was set-up to identify changes in Cd speciation during fermentation.

      • Chemical contaminants
      • Heavy Metals
  23. Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes respectively, exploit ureides differentially to mitigate the deleterious effects of cadmium toxicity

    • Plant and Soil
    • Purpose Ureides, allantoin and allantoate, are N-rich compounds used for N transport in nodulated ureide legumes. Here, we investigated their role in response of Phaseolus vulgaris and Pisum sativum, representing ureide and amide legumes, respectively, to Cd toxicity. Methods First, ureide content and ureide metabolism in P.

      • Chemical contaminants
      • Heavy Metals
  24. Alleviation of the Cadmium Toxicity by Application of a Microbial Derived Compound, Ectoine

    • Water, Air, & Soil Pollution
    • Heavy metals are natural components that are formed as a result of biotic activities, accumulate in the ecosystem because they cannot be biodegraded, and thus cause environmental stress.

      • Chemical contaminants
      • Heavy Metals
  25. Zinc and iron enrichment of vermicompost can reduce the arsenic load in rice grain: An investigation through pot and field experiments

    • Journal of Cleaner Production
    • The heavy metalloid arsenic (As), occurring in both trivalent and pentavalent is extremely toxic and has detrimental effect on humans through water-soil-crop transfer. Previously organic and inorganic amendments have been used separately for mitigation of As in rice but there exists a research gap regarding use of them simultaneously.

      • Chemical contaminants
      • Heavy Metals