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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 374

  1. Infections caused by Clostridium perfringens and Paeniclostridium sordellii after unsafe abortion

    • Sat, 09/24/2022 - 04:00
    • The Lancet Infectious Diseases
      • Bacterial pathogens
      • Clostridium perfringens
  2. Effects of litter from antimicrobial-fed broiler chickens on soil bacterial community structure and diversity

    • Thu, 09/22/2022 - 04:00
    • Canadian Journal of Microbiology
    • This study examined changes in soil bacterial community composition and diversity in response to fertilization with litter from chickens fed a diet without antibiotics and with bambermycin, penicillin, bacitracin, salinomycin, or mix of salinomycin and bacitracin. Litter (27.5 T/ha) was applied to 24 agricultural plots in the Fraser Valley of British Columbia. Nonfertilized plots were used as a negative control.

      • Bacterial pathogens
      • Clostridium perfringens
  3. Clostridium perfringens associated with dairy farm systems show diverse genotypes

    • Mon, 09/19/2022 - 04:00
    • International Journal of Food Microbiology
    • Clostridium perfringens is a bacterial species of importance to both public and animal health. Frequently found in food system environments, it presents a risk to food animal health such as dairy herds, and may cross contaminate associated ingredients or food products, with potential to cause sporadic and outbreaks of disease in human populations, including gastroenteric illness. In this study, we characterized C.

      • Bacterial pathogens
      • Clostridium perfringens
  4. Rapid Identification of Different Pathogenic Spore-Forming Bacteria in Spice Powders Using Surface-Enhanced Raman Spectroscopy and Chemometrics

    • Sat, 09/17/2022 - 04:00
    • Food Analytical Methods
    • Bacterial spores were isolated and purified from three powder spices: garlic powder, onion powder, and five-spice powder. The rapid identification of different bacteriophages was achieved by surface-enhanced Raman spectroscopy (SERS) combined with chemometrics. Five bacilli were isolated in the powdered spices: Clostridium perfringens, Bacillus subtilis, Bacillus amyloliquefaciens, Bacillus licheniformis, and Paenibacillus pabuli.

      • Bacterial pathogens
      • Clostridium perfringens
  5. Characterizing the Contributions of Various Clostridium perfringens Enterotoxin Properties to In Vivo and In Vitro Permeability Effects

    • Thu, 09/08/2022 - 04:00
    • mSphere
    • mSphere, Ahead of Print. Clostridium perfringens enterotoxin (CPE) is thought to cause lethal enterotoxemia when absorbed from the intestinal lumen into the circulation. CPE action sequentially involves receptor-binding, oligomerization into a prepore, and pore formation.

      • Bacterial pathogens
      • Clostridium perfringens
  6. Lactobacillus casei displaying Clostridium perfringens NetB antigen protects chickens against necrotic enteritis

    • Tue, 09/06/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Necrotic enteritis is a serious economical disease of poultry caused by Clostridium perfringens. NetB toxin of Clostridium perfringens is considered the causative agent of necrotic enteritis. Following the withdrawal of in-feed antibiotic growth promoters, there has been an urgent need to develop alternative approaches such as vaccination.

      • Bacterial pathogens
      • Clostridium perfringens
  7. Systematic Review and Meta-Analysis on the Frequency of Antibiotic-Resistant Clostridium Species in Saudi Arabia

    • Tue, 08/30/2022 - 04:00
    • Antibiotics
    • Clostridium is a genus comprising Gram-positive, rod-shaped, spore-forming, anaerobic bacteria that cause a variety of diseases. However, there is a shortage of information regarding antibiotic resistance in the genus in Saudi Arabia. This comprehensive analysis of research results published up until December 2021 intends to highlight the incidence of antibiotic resistance in Clostridium species in Saudi Arabia.

      • Bacterial pathogens
      • Clostridium perfringens
  8. Characterization and optimization of bacteriophage cocktails to control Clostridium perfringens in vitro and in curry roux

    • Wed, 08/24/2022 - 04:00
    • International Journal of Food Microbiology
    • Clostridium perfringens is a major cause of foodborne disease in developed countries. The aim of this study was to isolate and characterize phages specific to C.

      • Bacterial pathogens
      • Clostridium perfringens
  9. A mixture of organic acids and thymol protects primary chicken intestinal epithelial cells from Clostridium perfringens infection in vitro

    • Wed, 08/03/2022 - 04:00
    • Poultry Science
    • Necrotic enteritis causes economic losses estimated to be up to 6 billion US dollars per year. Clinical and sub-clinical infections in poultry are also both correlated with decreased growth and feed efficiency. Moreover, in a context of increased antibiotic resistance, feed additives with enhanced antimicrobial properties are a useful and increasingly needed strategy.

      • Bacterial pathogens
      • Clostridium perfringens
  10. Intra-species diversity of Clostridium perfringens: A diverse genetic repertoire reveals its pathogenic potential

    • Fri, 07/22/2022 - 04:00
    • Frontiers in Microbiology
    • Clostridium perfringens is the causative agent of many enterotoxic diseases in humans and animals, and it is present in diverse environments (soil, food, sewage, and water). Multilocus Sequence Typing (MLST) and Whole Genome Sequencing (WGS) have provided a general approach about genetic diversity of C. perfringens; however, those studies are limited to specific locations and often include a reduced number of genomes. In this study, 372 C.

      • Bacterial pathogens
      • Clostridium perfringens
  11. Antioxidant and Antimicrobial Properties of Selected Fruit Juices

    • Fri, 07/15/2022 - 04:00
    • Plant Foods for Human Nutrition
    • Fruit and fruit juices are a valuable source of bioactive compounds, which can protect our organisms from oxidative stress. The phenolic compounds and other phytochemicals may affect the antimicrobial properties of juices. The aim of this study has been to evaluate antioxidant and antimicrobial properties of selected berry juices and vitamin C-rich fruit juices.

      • Bacterial pathogens
      • Clostridium perfringens
  12. The Native Microbial Community of Gastropod-Associated Phasmarhabditis Species Across Central and Southern California

    • Thu, 07/14/2022 - 04:00
    • Frontiers in Microbiology
    • Nematodes in the genus Phasmarhabditis can infect and kill slugs and snails, which are important agricultural pests. This useful trait has been commercialized by the corporation BASF after they mass produced a product labeled Nemaslug®. The product contains Phasmarhabditis hermaphrodita, which has been cultured with Moraxella osloensis, a bacterial strain that was originally thought to be responsible for causing mortality in slugs and snails.

      • Bacterial pathogens
      • Clostridium perfringens
  13. The Specificity of ParR Binding Determines the Incompatibility of Conjugative Plasmids in Clostridium perfringens

    • Wed, 06/22/2022 - 04:00
    • mBio
    • mBio, Ahead of Print.

      • Bacterial pathogens
      • Clostridium perfringens
  14. Mining transcriptome data: Utilization of environmentally regulated promoters for protein expression and purification in Clostridium perfringens

    • Sat, 06/18/2022 - 04:00
    • Journal of Microbiological Methods
    • Clostridium perfringens is a Gram-positive pathogen with low GC content.

      • Bacterial pathogens
      • Clostridium perfringens
  15. Battling Enteropathogenic Clostridia: Phage Therapy for Clostridioides difficile and Clostridium perfringens

    • Mon, 06/13/2022 - 04:00
    • Frontiers in Microbiology
    • The pathogenic Clostridioides difficile and Clostridium perfringens are responsible for many health care-associated infections as well as systemic and enteric diseases. Therefore, they represent a major health threat to both humans and animals. Concerns regarding increasing antibiotic resistance (related to C. difficile and C. perfringens) have caused a surge in the pursual of novel strategies that effectively combat pathogenic infections, including those caused by both pathogenic species.

      • Bacterial pathogens
      • Clostridium perfringens
  16. Biofilm formation, antimicrobial assay, and toxin-genotypes of Clostridium perfringens type C isolates cultured from a neonatal Yangtze finless porpoise

    • Sat, 06/04/2022 - 04:00
    • Archives of Microbiology
    • This is a culture-dependent study with the objective of pure culturing and characterizing pathogenic bacteria from the blowhole, lung, stomach and fecal samples of a neonatal crucially endangered Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis) that died 27 days after birth. Bacteria were inoculated using a swab onto blood and MacConkey agar plates and representative isolates were identified through 16S rRNA gene sequence analysis.

      • Bacterial pathogens
      • Clostridium perfringens
  17. Reevaluation of whether a Functional Agr-like Quorum-Sensing System Is Necessary for Production of Wild-Type Levels of Epsilon-Toxin by Clostridium perfringens Type D Strains

    • Sat, 06/04/2022 - 04:00
    • mBio
    • mBio, Volume 13, Issue 2, April 2022. Clostridium perfringens type B and D strains produce epsilon-toxin (ETX). Our 2011 mBio study (mBio 2:e00275-11, 2011, https://doi.org/10.1128/mBio.00275-11) reported that the Agr quorum-sensing (QS) system regulates ETX production by type D strain CN3718. However, subsequent studies have brought that conclusion into question.

      • Bacterial pathogens
      • Clostridium perfringens
  18. Inhibition of Virulence Gene Expression in Salmonella Dublin, Escherichia coli F5 and Clostridium perfringens Associated With Neonatal Calf Diarrhea by Factors Produced by Lactic Acid Bacteria During Fermentation of Cow Milk

    • Thu, 05/12/2022 - 04:00
    • Frontiers in Microbiology
    • Diarrhea is a major health problem in neonatal and young calves worldwide. It can be caused by a variety of infectious agents, including the bacteria Salmonella enterica serovar Dublin (S. Dublin), enterotoxigenic Escherichia coli (ETEC), and Clostridium perfringens. Preventive alternatives to antibiotic treatment should be identified.

      • Bacterial pathogens
      • Clostridium perfringens
      • Salmonella
  19. Survival of Clostridium perfringens, Staphylococcus aureus, Listeria monocytogenes and Salmonella enterica in alternatively cured ham during cooking and process deviations

    • Fri, 05/06/2022 - 04:00
    • LWT
    • Boneless hams were prepared with four different brines and inoculated on the surface and at a depth of 1 cm with multiple strains of Clostridium perfringens, Staphylococcus aureus, Listeria monocytogenes and Salmonella enterica. Hams were processed with a standard, low relative humidity or interrupted process cycle to an end point temperature of 70 °C. Microbiological populations were determined at the beginning, mid-point and end of the cycles.

      • Bacterial pathogens
      • Clostridium perfringens
      • Listeria monocytogenes
      • Salmonella
      • Staphylococcus aureus
  20. Outbreaks of Acute Necrotic Enteritis and Haemolytic Crisis and Renal Disease Associated with Clostridium perfringens in Captive Toucans (Ramphastos spp)

    • Thu, 04/28/2022 - 04:00
    • Journal of Comparative Pathology
    • Four toco toucans (Ramphastos toco), one channel-billed toucan (Ramphastos vitellinus) and one white-throated toucan (Ramphastos tucanus) died in two disease outbreaks in the same aviary in 2011 and 2016.

      • Bacterial pathogens
      • Clostridium perfringens
  21. Dietary ellagic acid ameliorated Clostridium perfringens-induced subclinical necrotic enteritis in broilers via regulating inflammation and cecal microbiota

    • Thu, 04/21/2022 - 04:00
    • Journal of Animal Science and Biotechnology
    • Background Subclinical necrotic enteritis (SNE), a common intestinal disease of broiler caused by Clostridium perfringens, could reduce production performance of broilers by chronic intestinal damage and poor absorption of nutrients. Ellagic acid (EA) has been reported to present antioxidant and anti-inflammatory properties on human and animals in many aspects. This study was conducted to evaluate the effect and mechanism of EA in relieving SNE in broilers induced by C.

      • Bacterial pathogens
      • Clostridium perfringens
  22. Inhibitory effects of reuterin on biofilm formation, quorum sensing and virulence genes of Clostridium perfringens

    • Thu, 04/21/2022 - 04:00
    • LWT
    • Clostridium perfringens (C. perfringens) have been considered as one of the most common causes of human and veterinary gastrointestinal diseases. Reuterin is a broad-spectrum antimicrobial agent produced by certain Lactobacillus reuteri (L. reuteri) strains.

      • Bacterial pathogens
      • Clostridium perfringens
  23. New Mutants of Epsilon Toxin from Clostridium perfringens with an Altered Receptor-Binding Site and Cell-Type Specificity

    • Sun, 04/17/2022 - 04:00
    • Toxins
    • Epsilon toxin (Etx) from Clostridium perfringens is the third most potent toxin after the botulinum and tetanus toxins. Etx is the main agent of enterotoxemia in ruminants and is produced by Clostridium perfringens toxinotypes B and D, causing great economic losses. Etx selectively binds to target cells, oligomerizes and inserts into the plasma membrane, and forms pores.

      • Bacterial pathogens
      • Clostridium botulinum
      • Clostridium perfringens
  24. Polyphenolic phytochemicals as natural feed additives to control bacterial pathogens in the chicken gut

    • Tue, 04/12/2022 - 04:00
    • Archives of Microbiology
    • Poultry provides an important protein source consumed globally by human population, and simultaneously, acts as a substantial reservoir of antibiotic resistant bacterial species such as Escherichia coli, Salmonella, Campylobacter, Clostridium perfringens. These bacterial species can include commensal strains with beneficial roles on poultry health and productivity, and pathogenic strains not only to poultry but zoonotically to man.

      • Bacterial pathogens
      • Campylobacter
      • Clostridium perfringens
      • Salmonella
  25. Prevalence, Antibiotic Resistance, Toxin-Typing and Genotyping of Clostridium perfringens in Raw Beef Meats Obtained from Qazvin City, Iran

    • Sat, 03/05/2022 - 12:00
    • Antibiotics
    • Clostridium perfringens is one of the highest prevailing spore-forming foodborne pathogens, which is widely distributed and causes severe disease and outbreaks in humans and animals. Raw meat and poultry are the main vehicles of this pathogen. In this study, we investigated the prevalence, antibiotic resistance pattern, toxin-encoding genes and genetic diversity of C.

      • Bacterial pathogens
      • Clostridium perfringens