An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 1766

  1. Dispersive Micro Solid Phase Extraction Based Ionic Liquid Functionalized ZnO Nanoflowers Couple with Chromatographic Methods for Rapid Determination of Aflatoxins in Wheat and Peanut Samples

    • Sun, 05/22/2022 - 04:00
    • Food Chemistry
      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  2. Eco-friendly ‘ochratoxin A’ control in stored licorice roots – quality assurance perspective

    • Sun, 05/22/2022 - 04:00
    • Food Additives & Contaminants: Part A
      • Natural toxins
      • Mycotoxins
  3. Fumigation of Brazil nuts with allyl isothiocyanate to inhibit the growth of Aspergillus parasiticus and aflatoxin production

    • Sun, 05/22/2022 - 04:00
    • Journal of the Science of Food and Agriculture
    • Journal of the Science of Food and Agriculture, Volume 102, Issue 8, Page 3487-3487, June 2022.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  4. Adsorption of deoxynivalenol by APTS-TEOS modified eggshell powder

    • Sat, 05/21/2022 - 04:00
    • Food Chemistry
      • Natural toxins
      • Mycotoxins
  5. Effectiveness of beetroot extract in SH-SY5Y neuronal cell protection against Fumonisin B1, Ochratoxin A and its combination

    • Sat, 05/21/2022 - 04:00
    • Food and Chemical Toxicology
      • Natural toxins
      • Mycotoxins
  6. Costus speciosus extract protects against the oxidative damage of zearalenone via modulation of inflammatory cytokines, Nrf2 and iNOS gene expression in rats

    • Fri, 05/20/2022 - 04:00
    • Toxicon
    • Zearalenone (ZEN) is a non-steroidal estrogenic mycotoxin that induces severe health disturbances in humans and animals. This study aimed to determine the bioactive compounds in Costus speciosus extract (CSE) using GC-MS and evaluate its protective capability against ZEN-induced oxidative damage, genotoxicity, and cytotoxicity in rats. Six groups of male Sprague Dawley rats were treated orally for 15 days including the control group, CSE-treated groups at low (200 mg/kg b.

      • Natural toxins
      • Mycotoxins
  7. Carry-Over of Zearalenone and Its Metabolites to Intestinal Tissues and the Expression of CYP1A1 and GSTπ1 in the Colon of Gilts before Puberty

    • Thu, 05/19/2022 - 04:00
    • Toxins
    • The objective of this study was to evaluate whether low doses of zearalenone (ZEN) affect the carry-over of ZEN and its metabolites to intestinal tissues and the expression of CYP1A1 and GSTp1 in the large intestine.

      • Natural toxins
      • Mycotoxins
  8. Simultaneous Determination of Aflatoxins and Benzo(a)pyrene in Vegetable Oils Using Humic Acid-Bonded Silica SPE HPLC–PHRED–FLD

    • Thu, 05/19/2022 - 04:00
    • Toxins
    • In the present work, a rapid, accurate, and cost-effective method was developed for the simultaneous quantification of aflatoxins and benzo(a)pyrene in lipid matrices, using solid-phase extraction (SPE) via humic acid-bonded silica (HAS) sorbents, followed by high-performance liquid chromatography coupled with photochemical post-column reactor fluorescence spectroscopy (HPLC–PHRED–FLD) analysis.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  9. Deoxynivalenol enhances estrogen receptor alpha-induced signaling by ligand-independent transactivation

    • Wed, 05/18/2022 - 05:00
    • Food and Chemical Toxicology
    • Deoxynivalenol (DON), which is one of the prevalent mycotoxins in food and feeds, exerts adverse effects on animal and human health. These effects are mainly associated with its ribotoxic properties, although few studies suggest the involvement of other mechanisms of action. To assess the ability of DON to disrupt estrogen signaling, we conducted an in vitro study using MCF-7 and MDA-MB-231 cells.

      • Natural toxins
      • Mycotoxins
  10. Degradation of Ochratoxin A by a UV-Mutated Aspergillus niger Strain

    • Tue, 05/17/2022 - 04:00
    • Toxins
    • Ochratoxin A (OTA) is a mycotoxin that can contaminate a wide range of crops such as grains and grapes. In this study, a novel fungal mutant strain (FS-UV-21) with a high OTA degradation rate (74.5%) was obtained from Aspergillus niger irradiated with ultraviolet light (15 W for 20 min).

      • Natural toxins
      • Mycotoxins
  11. An ultrasensitive CH3NH3PbBr3 quantum dots@SiO2-based electrochemiluminescence sensing platform using an organic electrolyte for aflatoxin B1 detection in corn oil

    • Mon, 05/16/2022 - 04:00
    • Food Chemistry
    • Mycotoxins contamination, especially aflatoxin B1 (AFB1) in edible oils, is a health hazard. Therefore, AFB1 trace analysis methods are urgently needed. Electrochemiluminescence (ECL) is a popular sensing method because of its low background interference and high sensitivity. However, existing ECL assays for AFB1 detection are based on aqueous rather than oil systems.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  12. Surface-anchored liquid crystal droplets for the semi-quantitative detection of Aflatoxin B1 in food samples

    • Mon, 05/16/2022 - 04:00
    • Food Chemistry
    • Aflatoxin B1 (AFB1) is a common food mycotoxin that can cause various diseases. Therefore, reliable detection methods are required to ensure food safety against mycotoxins. In this study, we design a liquid–crystal (LC)-based assay for rapid detection of AFB1 in food samples. The surface-anchored LC droplets on glass (5CBSADrop) are obtained via a solvent evaporation method.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  13. Cumulative Effects of Non-Aflatoxigenic Aspergillus flavus Volatile Organic Compounds to Abate Toxin Production by Mycotoxigenic Aspergilli

    • Sat, 05/14/2022 - 04:00
    • Toxins
    • Previously, authors reported that individual volatile organic compounds (VOCs) emitted by non-aflatoxigenic Aspergillus flavus could act as a mechanism of biocontrol to significantly reduce aflatoxins and cyclopiazonic acid (CPA) produced by toxigenic strains.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  14. Small GTPase RacA is critical for spore growth, patulin accumulation, and virulence of Penicillium expansum

    • Fri, 05/13/2022 - 04:00
    • Postharvest Biology and Technology
    • RacA is a signaling molecule of the small GTPase family that regulates fungal morphology and cellular function and activates NADPH oxidase (Nox) transmit signaling molecules. In this study, we performed subcellular localization analysis of RacA in P. expansum and by fusion expression of RacA with GFP, we found that RacA was mostly localized in the cytoplasm and organelle membranes.

      • Natural toxins
      • Mycotoxins
  15. Detoxification of Aflatoxin B1 by a Potential Probiotic Bacillus amyloliquefaciens WF2020

    • Tue, 05/10/2022 - 04:00
    • Frontiers in Microbiology
    • Microbial degradation is considered as an attractive method to eliminate exposure to aflatoxin B1 (AFB1), the most toxic mycotoxin that causes great economic losses and brings a serious threat to human and animal health, in food and feed. In this study, Bacillus amyloliquefaciens WF2020, isolated from naturally fermented pickles, could effectively degrade AFB1 ranging from 1 to 8 μg/ml, and the optimum temperature and pH value were 37–45°C and 8.0, respectively. Moreover, B.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  16. Detoxification of Ochratoxin A by pulsed light in grape juice and evaluation of its degradation products and safety

    • Mon, 05/09/2022 - 04:00
    • Innovative Food Science & Emerging Technologies
    • Pulsed light (PL) was used to remove Ochratoxin A (OTA) from clear grape juice in this study. Firstly, the factors of OTA degraded by PL were explored, and the OTA degradation rate was 95.29% after optimization by response surface methodology. Dose-response curves were most suitable for kinetic fitting of OTA degradation by PL treatment (R2 = 0.9937).

      • Natural toxins
      • Mycotoxins
  17. Investigation of UV light treatment (254 nm) on the reduction of aflatoxin M1 in skim milk and degradation products after treatment

    • Mon, 05/09/2022 - 04:00
    • Food Chemistry
    • This study investigates the reduction of aflatoxin M1 (AFM1) in skim milk by using ultraviolet light at 254 nm and the effects of influencing factors on the efficacy including treatment time (min), depth of samples (mm), contamination level (μg L-1), stirring, temperature, and fat content in milk. The colour and pH of milk samples were measured to evaluate the influence of the treatment on these values.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  18. The velvet-activated putative C6 transcription factor VadZ regulates development and sterigmatocystin production in Aspergillus nidulans

    • Sun, 05/08/2022 - 04:00
    • Fungal Biology
    • The NF-ƙB-type VosA–VelB velvet complex acts as a global regulator governing development and metabolism in fungi. One of the VosA-VelB-activated developmental (VAD) genes called vadZ is predicted to encode a 557-amino acid protein containing a highly conserved GAL4-type Zn(II)2Cys6 (or C6 zinc) binuclear cluster DNA-binding domain in Aspergillus nidulans.

      • Natural toxins
      • Mycotoxins
  19. Determination of aflatoxin B1 in rice flour based on an enzyme-catalyzed Prussian blue probe

    • Sat, 05/07/2022 - 04:00
    • LWT
    • Aflatoxin B1 (AFB1) is a toxin that is widely present in food and feed and poses a serious threat to the health of humans and livestock. In this work, we proposed the quantitative detection method of AFB1 contamination using a simple, sensitive, and specific colorimetric immunoassay based on gold nanoparticles labeled with glucose oxidase (GOx)/rabbit anti-mouse immunoglobulin G.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  20. Dietary Exposure and Risk Assessment of Mycotoxins in Thyme and Thyme-Based Products Marketed in Lebanon

    • Sat, 05/07/2022 - 04:00
    • Toxins
    • This study aimed at evaluating the incidence of aflatoxin B1 (AFB1) and ochratoxin A (OTA) in thyme and thyme-based products, related dietary exposure, and cancer risk for regular and high consumption. A total of 160 samples were collected, and 32 composite samples were analyzed. AFB1 and OTA were respectively found in 84% (27/32) and 38% (12/32) of the samples.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  21. Development of Fluorescent Immunochromatographic Test Strip for Qualitative and Quantitative Detection of Zearalenone

    • Fri, 05/06/2022 - 04:00
    • Food Analytical Methods
    • Zearalenone (ZEN), which is usually generated by Fusarium species, is common contamination of corn. ZEN induces estrogen effects and disrupts the reproductive system of humans and animals. Herein, we established a method of quantum dots (QDs) immunochromatographic test strips for the detection of ZEN. In this method, QDs (Q2605, G2701A) and anti-ZEN monoclonal antibodies were conjugated by carbodiimide.

      • Natural toxins
      • Mycotoxins
  22. Targeted and non-targeted analysis of pesticides and aflatoxins in baby foods by liquid chromatography coupled to quadrupole Orbitrap mass spectrometry

    • Fri, 05/06/2022 - 04:00
    • Food Control
    • In this study, 21 pesticides and 4 aflatoxins were monitored in baby food marketed in Brazil, applying ultra-high-performance liquid chromatography coupled to quadrupole-Orbitrap mass spectrometry (UHPLC-Q-Orbitrap-MS).

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  23. A Preliminary Study to Classify Corn Silage for High or Low Mycotoxin Contamination by Using near Infrared Spectroscopy

    • Wed, 05/04/2022 - 05:00
    • Toxins
    • Mycotoxins should be monitored in order to properly evaluate corn silage safety quality. In the present study, corn silage samples (n = 115) were collected in a survey, characterized for concentrations of mycotoxins, and scanned by a NIR spectrometer.

      • Natural toxins
      • Mycotoxins
  24. Mycotoxin Exposure in Children through Breakfast Cereal Consumption in Chile

    • Wed, 05/04/2022 - 05:00
    • Toxins
    • Mycotoxins are unavoidable contaminants produced by fungi in food, especially grains. This study aimed to measure the occurrence and levels of total aflatoxins (AFs); ochratoxin A (OTA); zearalenone (ZEN); fumonisins B1, B2, and B3 (FUM); deoxynivalenol (DON); and T-2/HT-2 toxins in the four most commonly consumed breakfast cereals in Chile and to assess mycotoxin exposure and risk in children aged 2 to 13 years due to cereal consumption.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  25. Evaluation of Toxicant-Associated Fatty Liver Disease and Liver Neoplastic Progress in Sprague-Dawley Rats Treated with Low Doses of Aflatoxin B1 Alone or in Combination with Extremely Low Frequency Electromagnetic Fields

    • Wed, 05/04/2022 - 05:00
    • Toxins
    • The term toxicant-associated fatty liver disease (TAFLD) has been proposed to describe fatty liver diseases connected to toxicants other than alcohol. Aflatoxins are mycotoxins commonly found as contaminants in foods and feeds, which are known liver toxicants and potential candidates as potential causes of TAFLD.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
      • Viruses
      • Hepatitis