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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 96

  1. Association of Common Zoonotic Pathogens With Concentrated Animal Feeding Operations

    • Mon, 01/10/2022 - 16:00
    • Frontiers in Microbiology
    • Animal farming has intensified significantly in recent decades, with the emergence of concentrated animal feeding operations (CAFOs) in industrialized nations. The congregation of susceptible animals in CAFOs can lead to heavy environmental contamination with pathogens, promoting the emergence of hyper-transmissible, and virulent pathogens.

      • Staphylococcus aureus
      • Hepatitis
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
      • Viruses
  2. Cryptosporidium parvum Pyruvate Kinase Inhibitors With in vivo Anti-cryptosporidial Efficacy

    • Mon, 01/03/2022 - 16:00
    • Frontiers in Microbiology
    • Cryptosporidium parvum is a highly prevalent protozoan parasite that causes a diarrheal disease in humans and animals worldwide. Thus far, the moderately effective nitazoxanide is the only drug approved by the United States Food and Drug Administration for treating cryptosporidiosis in immunocompetent humans. However, no effective drug exists for the severe disease seen in young children, immunocompromised individuals and neonatal livestock. C.

      • Heavy Metals
      • Cryptosporidium parvum
      • Chemical contaminants
      • Parasites
  3. Small ruminants and zoonotic cryptosporidiosis

    • Thu, 11/18/2021 - 02:01
    • Parasitology Research
    • Sheep and goats are commonly infected with three Cryptosporidium species, including Cryptosporidium parvum, Cryptosporidium ubiquitum, and Cryptosporidium xiaoi, which differ from each in prevalence, geographic distribution, and public health importance. While C. parvum appears to be a dominant species in small ruminants in European countries, its occurrence in most African, Asian, and American countries appear to be limited.

      • Cryptosporidium parvum
      • Parasites
  4. Phenotypic Antimicrobial Susceptibility and Genotypic Characterization of Clinical Ureaplasma Isolates Circulating in Shanghai, China

    • Fri, 10/08/2021 - 16:00
    • Frontiers in Microbiology
    • There is a growing global concern regarding the rise of antimicrobial resistance among Ureaplasma spp. isolates. However, studies on the antimicrobial susceptibility profiles, resistance mechanisms, and clonality of Ureaplasma spp. clinical isolates are still limited and cover only some geographic regions.

      • Cryptosporidium parvum
      • Parasites
  5. Prevalence of intestinal parasitic infections and their associated risk factors among preschool and school children in Egypt

    • Thu, 09/30/2021 - 08:02
    • PLOS ONE
    • by Walid Elmonir, Haitham Elaadli, Anan Amer, Hammed El-Sharkawy, Mohamed Bessat, Samy F. Mahmoud, Mustafa Shukry Atta, Wael F. El-Tras

      • Giardia lamblia
      • Cryptosporidium parvum
      • Parasites
  6. Improved diagnosis of gastrointestinal infections using a semi-automated multiplex real-time PCR for detection of enteropathogens

    • Tue, 09/14/2021 - 03:09
    • Microbiology
    • The identification of enteropathogens is critical for the clinical management of patients with suspected gastrointestinal infection. The FLOW multiplex PCR system (FMPS) is a semi-automated platform (FLOW System, Roche) for multiplex real-time PCR analysis.

      • Campylobacter
      • Norovirus
      • Salmonella
      • Shigella
      • Giardia lamblia
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
      • Viruses
  7. Prophylactic and therapeutic efficacy of clinoptilolite against Cryptosporidium parvum in experimentally challenged neonatal lambs

    • Thu, 09/09/2021 - 06:11
    • Veterinary Parasitology
    • Author(s): Ceren Dinler Ay, Huseyin Voyvoda, Pinar Alkim Ulutas, Tulin Karagenc, Bulent Ulutas

      • Cryptosporidium parvum
      • Parasites
  8. Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections

    • Wed, 08/25/2021 - 00:00
    • Antibiotics
    • Bacterial sexually transmitted infections (BSTIs) are becoming increasingly significant with the approach of a post-antibiotic era. While treatment options dwindle, the transmission of many notable BSTIs, including Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum, continues to increase. Bacteriophage therapy has been utilized in Poland, Russia and Georgia in the treatment of bacterial illnesses, but not in the treatment of bacterial sexually transmitted infections.

      • Shigella
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  9. Cryptosporidium and cryptosporidiosis in wild birds: A One Health perspective

    • Fri, 08/20/2021 - 02:01
    • Parasitology Research
    • Cryptosporidium is one of the most important parasitic protozoa that can be transmitted through food and water contamination. With the increasing report of Cryptosporidium infections in wild birds, especially in herbivorous waterfowl, concerns have been raised for oocyst contamination of water and food supplies, which in turn can cause human and domestic animal infections in areas neighboring wild birds’ habitats.

      • Cryptosporidium parvum
      • Parasites
  10. Molecular detection of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in school children at the Thai-Myanmar border

    • Sat, 07/31/2021 - 02:01
    • Parasitology Research
    • Few data are available on the genetic identity of enteric protists Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in humans in Thailand. In this study, 254 stool samples were collected from primary school children from Ratchaburi Province at the Thai-Myanmar border and examined for Cryptosporidium spp., G. duodenalis, E. bieneusi and Cyclospora cayetanensis using PCR techniques.

      • Giardia lamblia
      • Cryptosporidium parvum
      • Cyclospora cayetanensis
      • Parasites
  11. Mining Public Metagenomes for Environmental Surveillance of Parasites: A Proof of Principle

    • Wed, 06/30/2021 - 16:00
    • Frontiers in Microbiology
    • Parasites often have complex developmental cycles that account for their presence in a variety of difficult-to-analyze matrices, including feces, water, soil, and food. Detection of parasites in these matrices still involves laborious methods. Untargeted sequencing of nucleic acids extracted from those matrices in metagenomic projects may represent an attractive alternative method for unbiased detection of these pathogens.

      • Cryptosporidium parvum
      • Parasites
  12. Challenges for Cryptosporidium Population Studies

    • Fri, 06/11/2021 - 00:00
    • Genes
    • Cryptosporidiosis is ranked sixth in the list of the most important food-borne parasites globally, and it is an important contributor to mortality in infants and the immunosuppressed. Recently, the number of genome sequences available for this parasite has increased drastically. The majority of the sequences are derived from population studies of Cryptosporidium parvum and Cryptosporidium hominis, the most important species causing disease in humans.

      • Cryptosporidium parvum
      • Parasites
  13. Duration of Postdiarrheal Enteric Pathogen Carriage in Young Children in Low-resource Settings

    • Tue, 06/01/2021 - 12:01
    • Clinical Infectious Diseases
    • Background Prolonged enteropathogen shedding after diarrhea complicates the identification of etiology in subsequent episodes and is an important driver of pathogen transmission. A standardized approach has not been applied to estimate the duration of shedding for a wide range of pathogens.

      • Shigella
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  14. The Mucosal Innate Immune Response to Cryptosporidium parvum, a Global One Health Issue

    • Tue, 05/25/2021 - 16:00
    • Frontiers in Cellular and Infection Microbiology
    • Cryptosporidium parvum is an apicomplexan parasite that infects the intestinal epithelium of humans and livestock animals worldwide. Cryptosporidiosis is a leading cause of diarrheal-related deaths in young children and a major cause of economic loss in cattle operations. The disease is especially dangerous to infants and immunocompromised individuals, for which there is no effective treatment or vaccination.

      • Cryptosporidium parvum
      • Parasites
  15. Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection

    • Wed, 05/19/2021 - 10:01
    • Antimicrobial Agents and Chemotherapy
    • The intestinal protozoan Cryptosporidium is a leading cause of diarrheal disease and mortality in young children. There is currently no fully effective treatment for cryptosporidiosis, which has stimulated interest in anticryptosporidial development over the last ~10 years, with numerous lead compounds identified, including several tRNA synthetase inhibitors.

      • Heavy Metals
      • Antibiotic residues
      • Cryptosporidium parvum
      • Parasites
      • Chemical contaminants
  16. Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes

    • Sun, 05/02/2021 - 04:02
    • ACS Infectious Diseases
    • Developing effective therapeutics or preventive interventions for important health threats is greatly enhanced whenever accessible models can enable the assessment of clinically important outcomes. While no non-human model is ever perfect, inexpensive in vivo small animal models in such as mice are often of great help in assessing the relevant efficacy of potential interventions.

      • Campylobacter
      • Shigella
      • Giardia lamblia
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  17. Meat-borne parasites in the Arab world: a review in a One Health perspective

    • Fri, 04/16/2021 - 02:03
    • Parasitology Research
    • Meat-borne parasitic zoonoses are generally not well-monitored, and so understanding extent and overall prevalence is problematic. Without sufficient attention, their prevalence can become unexpectedly and unacceptably high. This review sheds light on meat-borne parasites in the Arab world, which includes all the Arab countries situated in the continents of Asia and Africa, with more than 400 million inhabitants distributed in 22 countries.

      • Parasites
      • Toxoplasma gondii
      • Cryptosporidium parvum
  18. The Use of Pulsed Light to Inactivate Cryptosporidium parvum Oocysts on High-Risk Commodities (Cilantro, Mesclun Lettuce, Spinach, and Tomatoes)

    • Sun, 03/07/2021 - 06:11
    • Food Control
    • Author(s): Shani Craighead, Runze Huang, Haiqiang Chen, Kalmia E. Kniel

      • Parasites
      • Cryptosporidium parvum
  19. Establishment and preliminary application of nanoparticle-assisted PCR assay for detection of Cryptosporidium spp.

    • Tue, 03/02/2021 - 02:03
    • Parasitology Research
    • Cryptosporidium is an important intestinal protozoan parasite that causes diarrhoea in humans and animals. To rapidly and specifically detect Cryptosporidium spp., we designed a pair of primers based on the small subunit ribosomal RNA (SSU rRNA) gene of Cryptosporidium spp. to be used in a new nanoparticle-assisted PCR (nano-PCR) assay.

      • Parasites
      • Giardia lamblia
      • Cryptosporidium parvum
  20. Cryptosporidiosis outbreak caused by Cryptosporidium parvum subtype IIdA20G1 in neonatal calves

    • Thu, 01/07/2021 - 22:09
    • Transboundary and Emerging Diseases
    • Cryptosporidium parvum is a major zoonotic pathogen responsible for outbreaks of severe diarrhea in humans and calves. Almost all investigations of cryptosporidiosis outbreaks caused by C. parvum have focused on its IIa subtype family in industrialized nations. From December 2018 to April 2019, approximately 200 neonatal calves on a large cattle farm in Hebei Province, China were diagnosed with watery diarrhea and over 40 died.

      • Cryptosporidium parvum
      • Parasites
  21. The effect of Cryptosporidium parvum, rotavirus, and coronavirus infection on the health and performance of male dairy calves

    • Fri, 12/11/2020 - 08:01
    • Journal of Dairy Science
    • The objective of this prospective cohort study was to investigate the effect of bovine coronavirus (BCoV), bovine rotavirus (BRoV), and Cryptosporidium parvum on dairy calf health and performance and to determine the prevalence of these pathogens. A total of 198 male dairy calves housed at a grain-fed veal facility were examined from June 11, 2018, to October 9, 2018. Calves were fed milk replacer twice daily and housed individually until weaning at 56 d.

      • Cryptosporidium parvum
      • Parasites
  22. Identification of Uncommon Cryptosporidiumviatorum (a Novel Subtype XVcA2G1c) and Cryptosporidium andersoni as Well as Common Giardia duodenalis Assemblages A and B in Humans in Myanmar

    • Wed, 11/25/2020 - 16:00
    • Frontiers in Cellular and Infection Microbiology
    • Cryptosporidium and Giardia are two important zoonotic intestinal protozoa responsible for diarrheal diseases in humans and animals worldwide. Feces from infected hosts, water and food contaminated by Cryptosporidium oocysts and Giardia cysts as well as predictors such as poverty have been involved in their transmission. Myanmar is one of the world’s most impoverished countries. To date, there are few epidemiological studies of Cryptosporidium and Giardia in humans.

      • Giardia lamblia
      • Cryptosporidium parvum
      • Parasites
  23. Newly identified Cryptosporidium parvum virus‐1 from newborn calves diarrhoea in Turkey

    • Thu, 11/19/2020 - 22:17
    • Transboundary and Emerging Diseases
    • Cryptosporidium is a common enteric parasite that primarily affects those immunocompromised susceptible individuals and newborns. Detailed investigations have revealed that Cryptosporidium (C.) oocysts contain dsRNA segments which are recently classified under the Partitiviridae family. The relationship between parasite and virus whether or not affect the clinical outcomes of newborn calf diarrhoea is not apparent.

      • Cryptosporidium parvum
      • Parasites
  24. Foodborne Outbreaks of Microbial Infection from Fresh Produce in Europe And North America: A Systematic Review of Data from This Millennium

    • Sat, 11/07/2020 - 22:15
    • International Journal of Food Science & Technology
    • This study focuses on foodborne outbreaks of microbial infection associated with fresh produce in Europe and North America from this millennium. A total of 277 outbreaks with 44,524 individual cases were identified. Foodborne pathogens associated with the most outbreak frequency include Cryptosporidium (20.5%) in Europe and Salmonella (52.2%) in North America although Norovirus (54.3%) and Salmonella (61.3%) were associated with the number of cases in Europe and North America respectively.

      • Viruses
      • Norovirus
      • Salmonella
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  25. Plasmodium falciparum Apicomplexan-Specific Glucosamine-6-Phosphate N-Acetyltransferase Is Key for Amino Sugar Metabolism and Asexual Blood Stage Development

    • Tue, 10/27/2020 - 10:04
    • mBio
    • ABSTRACT

      • Antibiotic residues
      • Cryptosporidium parvum
      • Chemical contaminants
      • Parasites