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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 76 - 100 of 180

  1. Development and evaluation of a molecular based protocol for detection and quantification of Cryptosporidium spp. In wastewater

    • Experimental Parasitology
    • Infections caused by protozoan parasites are a major public health concern globally. These infections are commonly diagnosed during water-borne outbreaks, necessitating accurate and highly sensitive detection procedures to assure public health protection. Current molecular techniques are challenged by several factors, such as low parasite concentration, inefficient DNA extraction methods, and inhibitors in environmental samples.

      • Parasites
      • Cryptosporidium parvum
  2. A review of the molecular epidemiology of Cryptosporidium spp. and Giardia duodenalis in the Middle East and North Africa (MENA) region

    • Infection, Genetics and Evolution
    • Cryptosporidium spp. and Giardia duodenalis are important protozoan parasites which are associated with diarrheal diseases in humans and animals worldwide. Relatively little is known about the molecular epidemiology of Cryptosporidium spp. and Giardia duodenalis in the Middle East Countries and North Africa (MENA region).

      • Parasites
      • Cryptosporidium parvum
      • Giardia lamblia
  3. Cryptosporidium species in non-human animal species in Latin America: Systematic review and meta-analysis

    • Veterinary Parasitology: Regional Studies and Reports
    • Cryptosporidiosis is an infection caused by a protozoon that inhabits the gastrointestinal tract. More than forty valid species have been described in the genus Cryptosporidium, infecting a broad range of hosts around the world, some with zoonotic transmission and others with predominant anthroponotic transmission.

      • Parasites
      • Cryptosporidium parvum
  4. Serum IgG Responses to gp15 and gp40 Protein-Derived Synthetic Peptides From Cryptosporidium parvum

    • Frontiers in Cellular and Infection Microbiology
    • Cryptosporidium spp. are responsible for moderate to severe diarrhea, mainly in children and immunocompromised patients. Using ELISA, the recognition of synthetic peptides generated from the sequences of the Cryptosporidium parvum gp40 and gp15 proteins by serum IgM and IgG antibodies from patients infected (cases) with Cryptosporidium hominis, C. parvum, and Cryptosporidium canis, and uninfected individuals (controls) was evaluated.

      • Parasites
      • Cryptosporidium parvum
  5. Diagnosis, risk factors analysis and first molecular characterization of Cryptosporidium spp. in horses from Rio de Janeiro, Brazil

    • Veterinary Parasitology: Regional Studies and Reports
    • An analysis was made of the frequency of Cryptosporidium spp. in fecal samples from horses raised on farms in the Teresópolis city, state of Rio de Janeiro, Brazil, and the risk factors that favored this infection. Between 2019 and 2020, 314 samples of equine feces were collected, 287 of which came from English Thoroughbred horses and 27 from ponies.

      • Parasites
      • Cryptosporidium parvum
  6. Prevalence, risk factor and diversity of Cryptosporidium in cattle in Latvia

    • Veterinary Parasitology: Regional Studies and Reports
    • The epidemiology of Cryptosporidium spp. in Latvia was investigated by testing fecal samples from 926 animals aged from one day to 24 years for the presence of Cryptosporidium spp. oocysts.

      • Parasites
      • Cryptosporidium parvum
  7. Functional characterization of a GH62 family α-L-arabinofuranosidase from Eupenicillium parvum suitable for monosaccharification of corncob arabinoxylan in combination with key enzymes

    • Enzyme and Microbial Technology
      • Parasites
      • Cryptosporidium parvum
  8. A guide to standardise artificial contamination procedures with protozoan parasite oocysts or cysts during method evaluation, using Cryptosporidium and leafy greens as models

    • Food Control
      • Parasites
      • Cryptosporidium parvum
  9. Interactions between Cryptosporidium parvum and bovine corona virus during sequential and simultaneous infection of HCT-8 cells

    • Microbes and Infection
      • Parasites
      • Cryptosporidium parvum
      • Viruses
      • COVID-19
  10. Association of Common Zoonotic Pathogens With Concentrated Animal Feeding Operations

    • Frontiers in Microbiology
    • Animal farming has intensified significantly in recent decades, with the emergence of concentrated animal feeding operations (CAFOs) in industrialized nations. The congregation of susceptible animals in CAFOs can lead to heavy environmental contamination with pathogens, promoting the emergence of hyper-transmissible, and virulent pathogens.

      • Staphylococcus aureus
      • Hepatitis
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
      • Viruses
  11. Cryptosporidium parvum Pyruvate Kinase Inhibitors With in vivo Anti-cryptosporidial Efficacy

    • Frontiers in Microbiology
    • Cryptosporidium parvum is a highly prevalent protozoan parasite that causes a diarrheal disease in humans and animals worldwide. Thus far, the moderately effective nitazoxanide is the only drug approved by the United States Food and Drug Administration for treating cryptosporidiosis in immunocompetent humans. However, no effective drug exists for the severe disease seen in young children, immunocompromised individuals and neonatal livestock. C.

      • Heavy Metals
      • Cryptosporidium parvum
      • Chemical contaminants
      • Parasites
  12. Small ruminants and zoonotic cryptosporidiosis

    • Parasitology Research
    • Sheep and goats are commonly infected with three Cryptosporidium species, including Cryptosporidium parvum, Cryptosporidium ubiquitum, and Cryptosporidium xiaoi, which differ from each in prevalence, geographic distribution, and public health importance. While C. parvum appears to be a dominant species in small ruminants in European countries, its occurrence in most African, Asian, and American countries appear to be limited.

      • Cryptosporidium parvum
      • Parasites
  13. Phenotypic Antimicrobial Susceptibility and Genotypic Characterization of Clinical Ureaplasma Isolates Circulating in Shanghai, China

    • Frontiers in Microbiology
    • There is a growing global concern regarding the rise of antimicrobial resistance among Ureaplasma spp. isolates. However, studies on the antimicrobial susceptibility profiles, resistance mechanisms, and clonality of Ureaplasma spp. clinical isolates are still limited and cover only some geographic regions.

      • Cryptosporidium parvum
      • Parasites
  14. Prevalence of intestinal parasitic infections and their associated risk factors among preschool and school children in Egypt

    • PLOS ONE
    • by Walid Elmonir, Haitham Elaadli, Anan Amer, Hammed El-Sharkawy, Mohamed Bessat, Samy F. Mahmoud, Mustafa Shukry Atta, Wael F. El-Tras

      • Giardia lamblia
      • Cryptosporidium parvum
      • Parasites
  15. Improved diagnosis of gastrointestinal infections using a semi-automated multiplex real-time PCR for detection of enteropathogens

    • Microbiology
    • The identification of enteropathogens is critical for the clinical management of patients with suspected gastrointestinal infection. The FLOW multiplex PCR system (FMPS) is a semi-automated platform (FLOW System, Roche) for multiplex real-time PCR analysis.

      • Campylobacter
      • Norovirus
      • Salmonella
      • Shigella
      • Giardia lamblia
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
      • Viruses
  16. Prophylactic and therapeutic efficacy of clinoptilolite against Cryptosporidium parvum in experimentally challenged neonatal lambs

    • Veterinary Parasitology
    • Author(s): Ceren Dinler Ay, Huseyin Voyvoda, Pinar Alkim Ulutas, Tulin Karagenc, Bulent Ulutas

      • Cryptosporidium parvum
      • Parasites
  17. Potential for Phages in the Treatment of Bacterial Sexually Transmitted Infections

    • Antibiotics
    • Bacterial sexually transmitted infections (BSTIs) are becoming increasingly significant with the approach of a post-antibiotic era. While treatment options dwindle, the transmission of many notable BSTIs, including Neisseria gonorrhoeae, Chlamydia trachomatis, and Treponema pallidum, continues to increase. Bacteriophage therapy has been utilized in Poland, Russia and Georgia in the treatment of bacterial illnesses, but not in the treatment of bacterial sexually transmitted infections.

      • Shigella
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  18. Cryptosporidium and cryptosporidiosis in wild birds: A One Health perspective

    • Parasitology Research
    • Cryptosporidium is one of the most important parasitic protozoa that can be transmitted through food and water contamination. With the increasing report of Cryptosporidium infections in wild birds, especially in herbivorous waterfowl, concerns have been raised for oocyst contamination of water and food supplies, which in turn can cause human and domestic animal infections in areas neighboring wild birds’ habitats.

      • Cryptosporidium parvum
      • Parasites
  19. Molecular detection of Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in school children at the Thai-Myanmar border

    • Parasitology Research
    • Few data are available on the genetic identity of enteric protists Cryptosporidium spp., Giardia duodenalis, and Enterocytozoon bieneusi in humans in Thailand. In this study, 254 stool samples were collected from primary school children from Ratchaburi Province at the Thai-Myanmar border and examined for Cryptosporidium spp., G. duodenalis, E. bieneusi and Cyclospora cayetanensis using PCR techniques.

      • Giardia lamblia
      • Cryptosporidium parvum
      • Cyclospora cayetanensis
      • Parasites
  20. Mining Public Metagenomes for Environmental Surveillance of Parasites: A Proof of Principle

    • Frontiers in Microbiology
    • Parasites often have complex developmental cycles that account for their presence in a variety of difficult-to-analyze matrices, including feces, water, soil, and food. Detection of parasites in these matrices still involves laborious methods. Untargeted sequencing of nucleic acids extracted from those matrices in metagenomic projects may represent an attractive alternative method for unbiased detection of these pathogens.

      • Cryptosporidium parvum
      • Parasites
  21. Challenges for Cryptosporidium Population Studies

    • Genes
    • Cryptosporidiosis is ranked sixth in the list of the most important food-borne parasites globally, and it is an important contributor to mortality in infants and the immunosuppressed. Recently, the number of genome sequences available for this parasite has increased drastically. The majority of the sequences are derived from population studies of Cryptosporidium parvum and Cryptosporidium hominis, the most important species causing disease in humans.

      • Cryptosporidium parvum
      • Parasites
  22. Duration of Postdiarrheal Enteric Pathogen Carriage in Young Children in Low-resource Settings

    • Clinical Infectious Diseases
    • Background Prolonged enteropathogen shedding after diarrhea complicates the identification of etiology in subsequent episodes and is an important driver of pathogen transmission. A standardized approach has not been applied to estimate the duration of shedding for a wide range of pathogens.

      • Shigella
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites
  23. The Mucosal Innate Immune Response to Cryptosporidium parvum, a Global One Health Issue

    • Frontiers in Cellular and Infection Microbiology
    • Cryptosporidium parvum is an apicomplexan parasite that infects the intestinal epithelium of humans and livestock animals worldwide. Cryptosporidiosis is a leading cause of diarrheal-related deaths in young children and a major cause of economic loss in cattle operations. The disease is especially dangerous to infants and immunocompromised individuals, for which there is no effective treatment or vaccination.

      • Cryptosporidium parvum
      • Parasites
  24. Spontaneous Selection of Cryptosporidium Drug Resistance in a Calf Model of Infection

    • Antimicrobial Agents and Chemotherapy
    • The intestinal protozoan Cryptosporidium is a leading cause of diarrheal disease and mortality in young children. There is currently no fully effective treatment for cryptosporidiosis, which has stimulated interest in anticryptosporidial development over the last ~10 years, with numerous lead compounds identified, including several tRNA synthetase inhibitors.

      • Heavy Metals
      • Antibiotic residues
      • Cryptosporidium parvum
      • Parasites
      • Chemical contaminants
  25. Modeling Enteropathy or Diarrhea with the Top Bacterial and Protozoal Pathogens: Differential Determinants of Outcomes

    • ACS Infectious Diseases
    • Developing effective therapeutics or preventive interventions for important health threats is greatly enhanced whenever accessible models can enable the assessment of clinically important outcomes. While no non-human model is ever perfect, inexpensive in vivo small animal models in such as mice are often of great help in assessing the relevant efficacy of potential interventions.

      • Campylobacter
      • Shigella
      • Giardia lamblia
      • Cryptosporidium parvum
      • Bacterial pathogens
      • Parasites