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Research Publications (Food Safety)

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 508

  1. Dynamics and epidemiology of Toxoplasma gondii oocyst shedding in domestic and wild felids

    • Thu, 10/06/2022 - 04:00
    • Transboundary and Emerging Diseases
    • Transboundary and Emerging Diseases, Volume 69, Issue 5, Page 2412-2423, September 2022.

      • Parasites
      • Toxoplasma gondii
  2. A systematic review of Toxoplasma gondii genotypes in Gallus gallus domesticus worldwide: The focus is Brazil

    • Thu, 10/06/2022 - 04:00
    • Transboundary and Emerging Diseases
    • Transboundary and Emerging Diseases, Volume 69, Issue 5, Page 2440-2450, September 2022.

      • Parasites
      • Toxoplasma gondii
  3. Experimental infection of Toxoplasma gondii in specific pathogen-free and commercial broiler chicks

    • Mon, 10/03/2022 - 13:00
    • Comparative Immunology, Microbiology and Infectious Diseases
    • Toxoplasma gondii is an intracellular protozoan parasite that infects most warm-blooded animals, including humans, and causes toxoplasmosis. In this study, the pathogenicity of RH strain of T. gondii in broiler chicks was investigated and the susceptible tissues of chicks were clarified. Fourteen-day-old broiler chicks were injected intraperitoneally with 1×107, 1×106, and 1×105 tachyzoites of T. gondii, respectively.

      • Parasites
      • Toxoplasma gondii
  4. Molecular Detection and Genotyping of Toxoplasma gondii from Pigs for Human Consumption in Zhejiang and Jiangsu Provinces, Eastern China

    • Sat, 10/01/2022 - 04:00
    • Foodborne Pathogens and Disease
    • Toxoplasma gondii infections are common in humans and animals worldwide. Ingestion of raw or undercooked meat containing tissue cysts of T. gondii is one major source of transmission of this parasite. It is important to guarantee the meat quality of China since our pork industry produces about half of the world's pork. In this study, a total of 746 pig samples were collected from Zhejiang and Jiangsu provinces in eastern China, and examined for T.

      • Parasites
      • Toxoplasma gondii
  5. Clinical validation of visual LAMP and qLAMP assays for the rapid detection of Toxoplasma gondii

    • Mon, 09/26/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Humans are exposed to Toxoplasma gondii infection as pet cats gradually become family members and represent an increasing public health risk worldwide. Toxoplasmosis diagnosis constitutes an important measure for disease prevention and control. In this study, real-time fluorescence quantitative loop-mediated isothermal amplification (qLAMP) and visual LAMP detection technologies were established to conduct tests of T.

      • Parasites
      • Toxoplasma gondii
  6. The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection

    • Thu, 09/22/2022 - 04:00
    • mBio
    • mBio, Ahead of Print. Prenyldiphosphate synthases catalyze the reaction of allylic diphosphates with one or more isopentenyl diphosphate molecules to form compounds such as farnesyl diphosphate, used in, e.g., sterol biosynthesis and protein prenylation, as well as longer “polyprenyl” diphosphates, used in ubiquinone and menaquinone biosynthesis.

      • Parasites
      • Toxoplasma gondii
  7. Metabolic flexibilities and vulnerabilities in the pentose phosphate pathway of the zoonotic pathogen Toxoplasma gondii

    • Tue, 09/20/2022 - 04:00
    • PLOS Pathogens
    • by Ningbo Xia, Xuefang Guo, Qinghong Guo, Nishith Gupta, Nuo Ji, Bang Shen, Lihua Xiao, Yaoyu Feng Metabolic pathways underpin the growth and virulence of intracellular parasites and are therefore promising antiparasitic targets.

      • Parasites
      • Toxoplasma gondii
  8. Detection of Toxoplasma gondii oocysts in soil and risk mapping in an Island environment in the Northeast of Brazil

    • Sun, 09/18/2022 - 04:00
    • Transboundary and Emerging Diseases
    • Transboundary and Emerging Diseases, Accepted Article. Toxoplasmosis is an emerging and re-emerging infectious disease that can be transmitted through a contaminated environment. Environmental contamination is an emergency health issue and determining its occurrence is fundamental to a One Health approach. In this study we addressed the extent of environmental contamination and viability of T. gondii oocysts in soil in different environments on Fernando de Noronha Island, Brazil.

      • Parasites
      • Toxoplasma gondii
  9. Single domain antibodies against enteric pathogen virulence factors are active as curli fiber fusions on probiotic E. coli Nissle 1917

    • Fri, 09/16/2022 - 04:00
    • PLOS Pathogens
    • by Ilia Gelfat, Yousuf Aqeel, Jacqueline M. Tremblay, Justyna J. Jaskiewicz, Anishma Shrestha, James N. Lee, Shenglan Hu, Xi Qian, Loranne Magoun, Abhineet Sheoran, Daniela Bedenice, Colter Giem, Avinash Manjula-Basavanna, Amanda R. Pulsifer, Hann X. Tu, Xiaoli Li, Marilyn L. Minus, Marcia S. Osburne, Saul Tzipori, Charles B. Shoemaker, John M. Leong, Neel S.

      • Cryptosporidium parvium
      • Bacterial pathogens
      • Shigella
      • Parasites
  10. In vitro and in vivo anti−Toxoplasma activities of HDAC inhibitor Panobinostat on experimental acute ocular toxoplasmosis

    • Mon, 09/12/2022 - 04:00
    • Frontiers in Cellular and Infection Microbiology
    • Ocular toxoplasmosis (OT) is retinochoroiditis caused by Toxoplasma gondii infection, which poses a huge threat to vision. However, most traditional oral drugs for this disease have multiple side effects and have difficulty crossing the blood-retinal barrier, so the new alternative strategy is required to be developed urgently. Histone deacetylases (HDAC) inhibitors, initially applied to cancer, have attracted considerable attention as potential anti-Toxoplasma gondii drugs.

      • Parasites
      • Toxoplasma gondii
  11. Seasonal and Spatial Variations in the Presence of Giardia and Cryptosporidium in Rural Drinking Water Supply Systems in Different Municipalities of Antioquia, Colombia

    • Sun, 09/11/2022 - 04:00
    • Water, Air, & Soil Pollution
    • This study evaluated the seasonal and spatial variations in the presence of Giardia and Cryptosporidium in rural drinking water supply systems of different municipalities of Antioquia. The municipalities evaluated were Envigado, Caldas, Sabaneta, La Estrella, Itagüi, Bello, Barbosa, Copacabana, and Girardota, located in the department of Antioquia, Colombia. The experimentation was carried out over 9 sampling campaigns in the period between July 2019 and November 2020.

      • Cryptosporidium parvium
      • Parasites
      • Giardia lamblia
  12. Cryptosporidium infection in young dogs from Germany

    • Sun, 09/11/2022 - 04:00
    • Parasitology Research
    • Cryptosporidium is an enteric protozoan parasite which is able to cause severe gastrointestinal disease and is distributed all over the world. Since information about the prevalence of cryptosporidiosis in German dogs is rare, the aim of this study was to examine the occurrence of Cryptosporidium spp. in dogs and the potential zoonotic risk emanating from these infected animals. In total, 349 fecal samples of 171 dogs were collected during the dogs’ first year of life.

      • Parasites
      • Cryptosporidium parvium
  13. First report of rodent-adapted Cryptosporidium wrairi in an immunocompetent child, Spain

    • Sun, 09/11/2022 - 04:00
    • Parasitology Research
    • Cryptosporidiosis is a leading cause of childhood diarrhoea. Two species, Cryptosporidium hominis and Cryptosporidium parvum, are responsible for most confirmed cases globally. Close contact with pet animals can be an unnoticed source of children infections.

      • Cryptosporidium parvium
      • Parasites
  14. First report of Giardia duodenalis assemblage F in humans and dogs in southern Brazil

    • Sat, 09/10/2022 - 04:00
    • Comparative Immunology, Microbiology and Infectious Diseases
    • The present study aimed to molecularly characterize Giardia duodenalis from stool samples of humans, dogs, and cats. Molecular analyses were performed on 59 samples that tested positive for G. duodenalis on coproparasitological examinations.

      • Parasites
      • Giardia lamblia
  15. Development and evaluation of a real-time PCR for genotyping of Cryptosporidium spp. from water monitoring slides.

    • Sat, 09/10/2022 - 04:00
    • Experimental Parasitology
    • Cryptosporidium is an important cause of gastroenteritis globally and the main agent of waterborne outbreaks caused by protozoan parasites. Water monitoring for Cryptosporidium oocysts is by detection and enumeration using stained slide microscopy. Species identification (known as genotyping) may be undertaken post hoc and remains a specialist test, only undertaken in some laboratories.

      • Cryptosporidium parvium
      • Parasites
  16. Separate To Operate: the Centriole-Free Inner Core of the Centrosome Regulates the Assembly of the Intranuclear Spindle in Toxoplasma gondii

    • Thu, 09/08/2022 - 04:00
    • mBio
    • mBio, Ahead of Print. Centrosomes are the main microtubule-organizing center of the cell. They are normally formed by two centrioles, embedded in a cloud of proteins known as pericentriolar material (PCM). The PCM ascribes centrioles with their microtubule nucleation capacity. Toxoplasma gondii, the causative agent of toxoplasmosis, divides by endodyogeny. Successful cell division is critical for pathogenesis.

      • Parasites
      • Toxoplasma gondii
  17. Isolation and characterization of Toxoplasma gondii isolates from human congenital toxoplasmosis cases reveal a new virulent genotype in São Paulo, Brazil

    • Sat, 09/03/2022 - 04:00
    • Parasitology Research
    • Toxoplasma gondii causes severe disease in congenitally infected fetuses. The severity of fetal infection is related to the gestational stage at the time of maternal infection, parasite burden, and genotypic characteristics. South America has a high incidence of congenital toxoplasmosis and has the highest genotypic diversity of the parasite.

      • Parasites
      • Toxoplasma gondii
  18. An outbreak of cryptosporidiosis associated with drinking water in north-eastern Italy, August 2019: microbiological and environmental investigations

    • Fri, 09/02/2022 - 04:00
    • Eurosurveillance
    • is a leading global cause of waterborne disease, with many reported outbreaks related to main water supplies. In August 2019, an outbreak of cryptosporidiosis involving 80 cases occurred among 114 vacationers in a small municipality located in the Tuscan-Emilian Apennines, north-eastern Italy. After excluding a potential food-borne outbreak, the epidemiological investigation focussed on the hypothesis of a waterborne outbreak.

      • Parasites
      • Cryptosporidium parvium
  19. Transmission of Cryptosporidium by Fresh Vegetables

    • Fri, 09/02/2022 - 04:00
    • Consumption of fresh fruits and vegetables is increasing thanks to the awareness to the benefits to human health. Vegetables may become contaminated by enteric pathogens (protozoan parasites, bacteria and viruses) by irrigation with contaminated water, fertilization with fresh animal manure or by infected food handlers. Cryptosporidium spp. are fecal-oral protozoan parasites, known to be highly persistent in the environment, which facilitate the transmission of the infectious oocysts.

      • Parasites
      • Cryptosporidium parvium
  20. Role of landscape context in Toxoplasma gondii infection of invasive definitive and intermediate hosts on a World Heritage Island

    • Wed, 08/31/2022 - 04:00
    • International Journal for Parasitology: Parasites and Wildlife
    • Free-ranging cats are invasive species threatening biodiversity worldwide. They may also impose an environmental risk to humans and livestock through the transmission of zoonotic diseases. We investigated antibody levels against Toxoplasma gondii in free-ranging cats and black rats (definitive and representative intermediate hosts) by ELISA and determined their relationships with landscape environmental factors on Tokunoshima Island, Japan, the Natural World Heritage site.

      • Parasites
      • Toxoplasma gondii
  21. In Vitro Biological Activity of Natural Products from the Endophytic Fungus Paraboeremia selaginellae against Toxoplasma gondii

    • Wed, 08/31/2022 - 04:00
    • Antibiotics
    • Toxoplasma gondii is an apicomplexan pathogen able to infect a wide range of warm-blooded animals, including humans, leading to toxoplasmosis. Current treatments for toxoplasmosis are associated with severe side-effects and a lack efficacy to eradicate chronic infection. Thus, there is an urgent need for developing novel, highly efficient agents against toxoplasmosis with low toxicity.

      • Parasites
      • Toxoplasma gondii
  22. Investigation of Toxoplasma gondii, Neospora caninum and Tritrichomonas foetus in abortions of cattle, sheep and goats in Turkey: Analysis by real-time PCR, conventional PCR and histopathological methods

    • Mon, 08/29/2022 - 04:00
    • Comparative Immunology, Microbiology and Infectious Diseases
    • The aim of this study was to identify three parasitic major abortion agents in all cattle aborted fetus samples and N. caninum and T. gondii in sheep and goat aborted fetus sent to Elazig Veterinary Control Institute during two years. Total genomic DNAs were obtained using a commercial kit. Real-time PCR analysis was performed separately for each agent. Conventional PCR was set up for confirmation of positive samples.

      • Parasites
      • Toxoplasma gondii
  23. Antimicrobial, Antivirulence, and Antiparasitic Potential of Capsicum chinense Jacq. Extracts and Their Isolated Compound Capsaicin

    • Sat, 08/27/2022 - 04:00
    • Antibiotics
    • Bacterial, fungal, and parasitic infections increase morbimortality rates and hospital costs. This study aimed to assess the antimicrobial and antiparasitic activities of the crude extract from the seeds and peel of the pepper Capsicum chinense Jacq. and of the isolated compound capsaicin and to evaluate their ability to inhibit biofilm formation, eradicate biofilm, and reduce hemolysin production by Candida species.

      • Parasites
      • Toxoplasma gondii
  24. Pathogenic parasites in vegetables in the Middle East and North Africa: Occurrence of Ascaris eggs and Giardia cysts, and epidemiological implications

    • Thu, 08/25/2022 - 11:11
    • Food Control
    • Parasitic diseases are a major health problem in many developing countries. The consumption of contaminated fresh vegetables can play a crucial epidemiological role in the transmission of parasitic foodborne diseases including ascariasis and giardiasis. This review explored the occurrence of the pathogenic parasites Ascaris and Giardia on vegetables collected from markets, street vendors, groceries, and farms in the Middle East and North African countries.

      • Parasites
      • Giardia lamblia
  25. Occidiofungin: Actin Binding as a Novel Mechanism of Action in an Antifungal Agent

    • Wed, 08/24/2022 - 04:00
    • Antibiotics
    • The identification and development of natural products into novel antimicrobial agents is crucial to combat the rise of multidrug-resistant microorganisms. Clinical fungal isolates have been identified, which have shown resistance to all current clinical antifungals, highlighting a significant need to develop a novel antifungal agent. One of the natural products produced by the bacterium Burkholderia contaminans MS14 is the glycolipopeptide occidiofungin.

      • Parasites
      • Cryptosporidium parvium