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Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 224

  1. Antibacterial peptide NZ2114-loaded hydrogel accelerates Staphylococcus aureus-infected wound healing

    • Sun, 05/08/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Wound infection caused by Staphylococcus aureus (S. aureus) is a great challenge which has caused significant burden and economic loss to the medical system. NZ2114, a plectasin-derived peptide, is an antibacterial agent for preventing and treating S. aureus infection, especially for methicillin-resistant S. aureus (MRSA) infection.

      • Bacterial pathogens
      • Staphylococcus aureus
  2. Boosting expression level of plectasin in recombinant Pichia pastoris via 2A self-processing peptide assembly

    • Wed, 05/04/2022 - 05:00
    • Applied Microbiology and Biotechnology
    • Plectasin is a promising and potent antimicrobial peptide isolated from the fungus Pseudoplectania nigrella which has been heterologously expressed in various hosts. In this study, a four-copy cassette of plectasin was constructed via 2A peptide assembly to further increase its expression level in recombinant Pichia pastoris.

      • Bacterial pathogens
      • Staphylococcus aureus
  3. Effect of luxS encoding a synthase of quorum-sensing signal molecule AI-2 of Vibrio vulnificus on mouse gut microbiome

    • Sun, 05/01/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Autoinducer-2 (AI-2), a quorum-sensing signal molecule from the human pathogen Vibrio vulnificus, was assessed for its effect on the gut microbiome of mice. For this, we employed 16S rRNA sequencing to compare the gut microbiome of mice infected with either wild-type V. vulnificus or with the isotype ΔluxS that has a deletion in luxS which encodes the biosynthetic function of AI-2.

      • Bacterial pathogens
      • Vibrio
  4. Marine fungal metabolites as a source of drug leads against aquatic pathogens

    • Sat, 04/30/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Aquatic pathogens, including Vibrio, Edwardsiella, Pseudomonas, and Aeromonas, which could result in bacterial diseases to aquaculture, have seriously threatened the world aquaculture production. Marine-derived fungi, which could produce novel secondary metabolites with significant antibacterial activity, may be an important source for finding effective agents against aquatic pathogens.

      • Bacterial pathogens
      • Vibrio
  5. Investigation of chetomin as a lead compound and its biosynthetic pathway

    • Wed, 04/27/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Chaetomium fungi produce a diversity of bioactive compounds. Chaetomium cochliodes SD-280 possesses 91 secondary metabolite gene clusters and exhibits strong antibacterial activity. One of the active compounds responsible for that activity, chetomin, has a minimum inhibitory concentration (MIC) for anti-methicillin-resistant Staphylococcus aureus (MRSA) of 0.05 μg/mL (vancomycin: 0.625 μg/mL).

      • Bacterial pathogens
      • Staphylococcus aureus
      • Chemical contaminants
      • Heavy Metals
  6. In-depth genome analysis of Bacillus sp. BH32, a salt stress-tolerant endophyte obtained from a halophyte in a semiarid region

    • Tue, 04/19/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Endophytic strains belonging to the Bacillus cereus group were isolated from the halophytes Atriplex halimus L. (Amaranthaceae) and Tamarix aphylla L. (Tamaricaceae) from costal and continental regions in Algeria. Based on their salt tolerance (up to 5%), the strains were tested for their ability to alleviate salt stress in tomato and wheat. Bacillus sp.

      • Bacterial pathogens
      • Bacillus cereus
  7. Characterization of a bioactive meroterpenoid isolated from the marine-derived fungus Talaromyces sp.

    • Thu, 04/14/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • A new meroterpenoid, taladrimanin A (1), was isolated from a marine-derived fungus Talaromyces sp. HM6-1–1, together with eleven biogenetically related compounds (2–12). A plausible biosynthetic pathway for the meroterpenoids (1–4) was proposed. The planar structure of 1 was assigned by HRESIMS and NMR.

      • Bacterial pathogens
      • Staphylococcus aureus
      • Vibrio
  8. Effect of Nanosulfur Against Multidrug-Resistant Staphylococcus pseudintermedius and Pseudomonas aeruginosa

    • Thu, 04/07/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Multidrug resistance (MDR) has significantly increased in the past decades and the use of nanotechnology has opened new venues for novel treatments. Nanosulfur is a potent antimicrobial agent and a cheaper alternative to other nanomaterials. However, very few studies have been published on its activity against MDR organisms.

      • Bacterial pathogens
      • Staphylococcus aureus
  9. Salinity significantly affects intestinal microbiota and gene expression in striped catfish juveniles

    • Sun, 04/03/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • In the present study, juvenile striped catfish (Pangasianodon hypophthalmus), a freshwater fish species, have been chronically exposed to a salinity gradient from freshwater to 20 psu (practical salinity unit) and were sampled at the beginning (D20) and the end (D34) of exposure.

      • Bacterial pathogens
      • Vibrio
  10. Anti-hepatitis C virus drug simeprevir: a promising antimicrobial agent against MRSA

    • Sun, 03/27/2022 - 04:00
    • Applied Microbiology and Biotechnology
    • Abstract Staphylococcus aureus is a major human pathogen, and the appearance of methicillin-resistant S. aureus (MRSA) renders S. aureus infections more challenging to treat. Therefore, new antimicrobial drugs are urgently needed to combat MRSA infections. Drug repurposing is an effective and feasible strategy.

      • Bacterial pathogens
      • Staphylococcus aureus
      • Viruses
      • Hepatitis
  11. Changes in physiological states of Salmonella Typhimurium measured by qPCR with PMA and DyeTox13 Green Azide after pasteurization and UV treatment

    • Thu, 03/10/2022 - 12:00
    • Applied Microbiology and Biotechnology
    • Diarrheal diseases caused by Salmonella pose a major threat to public health, and assessment of bacterial viability is critical in determining the safety of food and drinking water after disinfection. Viability PCR could overcome the limitations of traditional culture-dependent methods for a more accurate assessment of the viability of a microbial sample.

      • Bacterial pathogens
      • Salmonella
  12. Non-thermal plasma induces changes in aflatoxin production, devitalization, and surface chemistry of Aspergillus parasiticus

    • Wed, 02/23/2022 - 06:00
    • Applied Microbiology and Biotechnology
    • Non-thermal plasma (NTP) represents the fourth state of matter composed of neutral molecules, atoms, ions, radicals, and electrons. It has been used by various industries for several decades, but only recently NTPs have emerged in fields such as medicine, agriculture, and the food industry. In this work, we studied the effect of NTP exposure on aflatoxin production, conidial germination and mycelial vitality, morphological and surface changes of conidia and mycelium.

      • Natural toxins
      • Aflatoxins
      • Mycotoxins
  13. Comparative analysis of microbial communities from different full-scale haloalkaline biodesulfurization systems

    • Sat, 02/12/2022 - 12:00
    • Applied Microbiology and Biotechnology
    • In biodesulfurization (BD) at haloalkaline and dO2-limited conditions, sulfide-oxidizing bacteria (SOB) effectively convert sulfide into elemental sulfur that can be used in agriculture as a fertilizer and fungicide. Here we show which bacteria are present in this biotechnological process. 16S rRNA gene amplicon sequencing of biomass from ten reactors sampled in 2018 indicated the presence of 444 bacterial Amplicon Sequence Variants (ASVs).

      • Bacterial pathogens
      • Vibrio
  14. A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism

    • Fri, 02/11/2022 - 06:00
    • Applied Microbiology and Biotechnology
    • The potential use of biological agents has become a major public health concern worldwide. According to the CDC classification, Bacillus anthracis and Clostridium botulinum, the bacterial pathogens that cause anthrax and botulism, respectively, are considered to be the most dangerous potential biological agents. Currently, there is no licensed vaccine that is well suited for mass immunization in the event of an anthrax or botulism epidemic.

      • Bacterial pathogens
      • Clostridium botulinum
  15. Targeting intestinal flora and its metabolism to explore the laxative effects of rhubarb

    • Wed, 02/09/2022 - 06:00
    • Applied Microbiology and Biotechnology
    • Rhubarb, a traditional herb, has been used in clinical practice for hundreds of years to cure constipation, but its mechanism is still not clear enough. Currently, growing evidence suggests that intestinal flora might be a potential target for the treatment of constipation. Thus, the aim of this study was to clarify the laxative effect of rhubarb via systematically analyzing the metagenome and metabolome of the gut microbiota.

      • Bacterial pathogens
      • Shigella
  16. Biomedical applications of L-alanine produced by Pediococcus acidilactici BD16 (alaD+)

    • Sat, 01/29/2022 - 12:00
    • Applied Microbiology and Biotechnology
    • L-alanine possesses extensive physiological functionality and tremendous pharmacological significance, therefore could be considered as potential ingredient for food, pharmaceutical, and personal care products. However, therapeutic properties of L-alanine still need to be addressed in detail to further strengthen its utilization as a viable ingredient for developing natural therapeutics with minimum side effects.

      • Bacterial pathogens
      • Staphylococcus aureus
      • Vibrio
  17. Identification of a novel glucuronyltransferase from Streptomyces chromofuscus ATCC 49982 for natural product glucuronidation

    • Thu, 01/27/2022 - 12:00
    • Applied Microbiology and Biotechnology
    • Glycosylation is an effective way to increase the polarity of natural products. UDP-glucuronyltransferases (UGTs) are commonly observed and extensively studied in phase II drug metabolism. However, UGTs in microorganisms are not well studied, which hampered the utilization of this type of enzyme in microbial glucuronidation of natural products.

      • Natural toxins
      • Mycotoxins
  18. Possible mechanisms for the equilibrium of ACC and role of ACC deaminase-producing bacteria

    • Sat, 01/22/2022 - 12:00
    • Applied Microbiology and Biotechnology
    • Plant growth-promoting rhizobacteria (PGPR) actively colonize the plant rhizosphere, which not only stimulates plants’ growth and development but also mitigates the adverse effects of abiotic stressors. Besides other techniques and approaches used for the alleviation of abiotic stress conditions, the utilization of PGPR with multiplant growth-promoting traits is desirable because the application of PGPR is pragmatic, sustainable, and environmentally friendly.

      • Produce Safety
      • Ethylene Sensitive
  19. Engineered nanomaterials in plant diseases: can we combat phytopathogens?

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • Abstract Engineered nanomaterials (ENM) have a high potential for use in several areas of agriculture including plant pathology. Nanoparticles (NPs) alone can be applied for disease management due to their antimicrobial properties. Moreover, nanobiosensors allow a rapid and sensitive diagnosis of pathogens because NPs can be conjugated with nucleic acids, proteins and other biomolecules.

      • Chemical contaminants
      • Pesticide residues
  20. Efficient production of immunologically active Shigella invasion plasmid antigens IpaB and IpaH using a cell-free expression system

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • Abstract Shigella spp. invade the colonic epithelium and cause bacillary dysentery in humans. Individuals living in areas that lack access to clean water and sanitation are the most affected. Even though infection can be treated with antibiotics, Shigella antimicrobial drug resistance complicates clinical management. Despite decades of effort, there are no licensed vaccines to prevent shigellosis.

      • Bacterial pathogens
      • Shigella
  21. Characterization of a novel broad-spectrum endolysin PlyD4 encoded by a highly conserved prophage found in Aeromonas hydrophila ST251 strains

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • Abstract Aeromonas hydrophila is a zoonotic pathogen that exhibits high level resistance to classic antibiotics and is a heavy burden for aquaculture industry. Lytic enzymes encoded by phages or prophages have shown potential for use against pathogenic bacteria. In this study, an intact prophage (named phAhD4) was identified from A. hydrophila D4. phAhD4 is highly conserved in all 10 published A.

      • Bacterial pathogens
      • Vibrio
  22. Dietary supplementation with microalgae enhances the zebrafish growth performance by modulating immune status and gut microbiota

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • Abstract Microalgae are known to be abundant in various habitats around the globe, and are rich in high value-added products such as fatty acids, polysaccharides, proteins, and pigments. Microalgae can be exploited as the basic and primitive food source of aquatic animals.

      • Bacterial pathogens
      • Vibrio
  23. Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin inhibit Listeria monocytogenes

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • Abstract Food safety affected by food-borne pathogen has received increasing attention by researchers. Listeria monocytogenes (L. monocytogenes), widespread in the environment, could easily cause some diseases. The aim of this study was to investigate how L.

      • Bacterial pathogens
      • Listeria monocytogenes
  24. Predicted functional genes for the biodegradation of xenobiotics in groundwater and sediment at two contaminated naval sites

    • Wed, 01/12/2022 - 22:17
    • Applied Microbiology and Biotechnology
    • The goals of this study were to predict the genes associated with the biodegradation of organic contaminants and to examine microbial community structure in samples from two contaminated sites.

      • Chemical contaminants
      • Dioxins
  25. Proteomic analysis of hexahydro-β-acids/hydroxypropyl-β-cyclodextrin inhibit Listeria monocytogenes

    • Wed, 01/12/2022 - 02:01
    • Applied Microbiology and Biotechnology

    • Abstract

      • Listeria monocytogenes
      • Bacterial pathogens