Research Publications (Food Safety)

The research investigates the effects of freeze-dried Spirulina maxima microcapsules in reducing testicular toxicity in rats and optimizing the in vitro release behavior of milk beverages using response surface methodology (RSM). Particle size, polydispersity index and zeta-potential were impacting microcapsules’ stability and bioactivity.

We investigated whether pretreatment with an egg white hydrolysate (EWH) protects the cardiovascular system, especially the resistance vessels, from damage promoted by Cd exposure at high levels. Male Wistar rats, divided into groups: 1) Control – tap water by gavage + distilled water i.p. (28 days); 2) Cd – tap water (28 days) + CdCl2 1 mg/kg i.p. (last 14 days); 3) EWH 1 mg/kg/day by gavage + distilled water i.p.

Cardiotoxicity is a serious side effect of arsenic trioxide (ATO) which hinders its clinical use in cancer chemotherapy. Danshensu (DSS) has potential applications in the food and healthcare industry to promote cardiovascular health. The experiment aims to investigate the effects of DSS against ATO-induced cardiotoxicity and its possible mechanism.

Moringa Oleifera (MO) has potential for nutritional and medical applications. We verified whether the administration of MO changed mineral accumulation patterns and mitigative effects of lead poisoning using Sprague–Dawley rats. MO leaves, aqueous leaf extracts, and seeds were administrated to rats in two different concentrations (100 and 600 mg/kg body weight/day) for 3 weeks.

Probiotic lactic acid bacteria exhibit metal ion binding properties, which can be employed as metal bio-adsorbents in the human system. Lead is a prevalent dietary contaminant that causes lead toxicity in humans, especially children. In the present investigation, we evaluated the indigenous lactobacilli for their lead bioadsorption potential that can offer a pre-emptive approach for bioremediating lead toxicity.

Fucoidan extracted from Fucus versiculosus was able to inhibit the replication of human noroviruses (hNoV) GII.4[P16] in zebrafish (Danio rerio) larvae. In the hNoV infected zebrafish larvae, a transcriptomic analysis showed significant upregulation (p < 0.01) of the interferons (IFNs) signaling related genes as well as a series of IFN-stimulated genes (ISGs) encoding antiviral effectors compared to the mock-infected controls.

We have investigated if EWH could counteract or prevent cardiovascular damage induced by high level of Cd exposure in rats. Male Wistar rats were treated for 14 days with: (A) Untreated - intraperitoneal (i.p.) injections of distilled water and tap water by gavage; (B) Cd − 1 mg/kg of bw/day of CdCl2 (i.p.) and tap water by gavage; (C) EWH – distilled water (i.p.) and 1 mg/kg/day of EWH by gavage; (D) CdEWH – both treatments.

Native and chemically modified whey proteins and their peptide derivatives are encountering the interest of nutraceutical and pharmaceutical industries, due to the numerous properties, ranging from antimicrobial to immunological and antitumorigenic, that result in the possibility to employ milk and its protein components in a wide range of treatment and prevention strategies.

Cordycepin (Cor) is a potent bioactive constituent of Cordyceps militaris, which has been used as a daily tonic food and herbal medicine in Asia. Cadmium (Cd) is a widespread neurotoxic environmental contaminant, and it has been detected as a pollutant in Cordyceps militaris. However, the potential effects of Cor on Cd neurotoxicity remains unknown.

Author(s): Ke Du, Xi Zheng, Junya Lv, Xin Zhong, Minjie Wei, Mingyan Liu

Author(s): En Yu, Daiwen Chen, Bing Yu, Yuheng Luo, Ping Zheng, Heng Yin, Xiangbing Mao, Zhiqing Huang, Jie Yu, Junqiu Luo, HuiYan, Jun He

Author(s): Ghedeir M. Alshammari, Wahidah H. Al-Qahtani, Mohammad A. Alshuniaber, Abu ElGasim A. Yagoub, Abdullrahman S. Al-Khalifah, Laila Naif Al-Harbi, Maha H. Alhussain, Sahar Abdulaziz AlSedairy, Mohammed Abdo Yahya

Author(s): Leilei Yu, Yaqi Yu, Yue Xiao, Fengwei Tian, Arjan Narbad, Qixiao Zhai, Wei Chen

Author(s): En Yu, Daiwen Chen, Bing Yu, Yuheng Luo, Ping Zheng, Heng Yin, Xiangbing Mao, Zhiqing Huang, Jie Yu, Junqiu Luo, HuiYan, Jun He

Author(s): T.R. Reshmitha, P. Nisha

Author(s): Qingfeng He, Yunjing Luo, Ziqi Xie

Author(s): Ning Li, Di Zhang, Shuai Cao, Mingwu Qiao, Pingan Zhang, Qiuyan Zhao, Yue Shen, Xianqing Huang, Lianjun Song

Author(s): Xiaoyang Xia, Zhen Zhang, Chang Zheng, Qianchun Deng, Mingming Zheng, Ling Han, Xia Xiang

Author(s): Chenglin Mu, Yifan Sheng, Qian Wang, Amr Amin, Xugang Li, Yingqiu Xie

Author(s): K. Chojnacka, A. Witek-Krowiak, D. Skrzypczak, K. Mikula, P. Młynarz

Author(s): Fangfang Yan, Li Zhao, Wanbing Chen, Qun Lu, Cuie Tang, Chengming Wang, Rui Liu

Author(s): José Eudes Gomes Pinheiro, Caroline Silveira Martinez, Paola Zambelli Moraes, José Eduardo Stasiaki, Maria Elisa Trost, Dalton Valentim Vassallo, Fernando Barbosa, Franck Maciel Peçanha, Francielli Weber Santos Cibin, Marta Miguel, Giulia Alessandra Wiggers

Author(s): Cui Tong, Peng Li, Li-Hui Yu, Lin Li, Kang Li, Yueli Chen, Shu-Hua Yang, Miao Long

Author(s): Sze Wing Ho, Hani El-Nezami, Nagendra P. Shah

Author(s): Monique Ellen Torres da Silva, Kely de Paula Correa, Marcio Arêdes Martins, Sérgio Luis Pinto da Matta, Hércia Stampini Duarte Martino, Jane Sélia dos Reis Coimbra