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Research Publications (Food Safety)

This page tracks research articles published in national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. Research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies (requires login) and FDA Grant Funding Agencies (requires login) are also tracked in Scopus.

Displaying 126 - 150 of 179

  1. Recent advances in the bioanalytical methods of polyethylene glycols and pegylated pharmaceuticals

    • Journal of Separation Science
    • Polyethylene glycols are synthetic polymers composed of repeating oxyethylene subunits, which have been known for non‐toxic, non‐immunogenic, non‐antigenic, good solubility in water and therefore approved for pharmaceutical applications.

  2. Multivariate image analysis–quantitative structure retention relationship study of polychlorinated biphenyls using partial least squares and radial basis function neural networks

    • Journal of Separation Science
    • Polychlorinated biphenyls belong to a class of hazardous and environmental pollutants. GC separation and experimental relative retention time evaluation of these compounds on a poly (94% methyl/5% phenyl) silicone based capillary non‐bonded and cross‐linked column are time‐consuming and expensive.

      • Chemical contaminants
  3. Trends in sensitive detection and rapid removal of sulfonamides: A review

    • Journal of Separation Science
    • Sulfonamides in environmental water, food, and feed are a major concern for both aquatic ecosystems and public health, because they may lead to the health risk of drug resistance. Thus, numerous sensitive detection and rapid removal methodologies have been established. This review summarizes the sample preparation techniques and instrumental methods used for sensitive detection of sulfonamides.

  4. Novel‐designed magnetic solid phase extraction method for extraction of some pesticides in vegetable and fruit juices

    • Journal of Separation Science
    • A new version of magnetic solid phase extraction performed in a narrow bore tube has been proposed for the extraction and preconcentration of different pesticides from various vegetable and fruit juices followed by gas chromatography. A few mg of C8@SiO2@Fe3O4 nanoparticles are added into an aqueous sample solution placed in a narrow bore tube. The sorbent particles move down through the tube under gravity force and are collected at the end of the tube by applying an external magnetic field.

      • Pesticide residues
      • Chemical contaminants
  5. Fe3O4 nanoparticles coated with polyhedral oligomeric silsesquioxanes and β‐cyclodextrin for magnetic solid phase extraction of carbaryl and carbofuran

    • Journal of Separation Science
    • In this paper, porous sandwich structure Fe3O4 nanoparticles coated by polyhedral oligomeric silsesquioxanes and β‐cyclodextrin were prepared by surface polymerization using as the magnetic solid phase extraction adsorbent for the extraction and determination of carbaryl and carbofuran.

      • Chemical contaminants
  6. Dual‐layer column filtration cleanup and gas chromatography‐tandem mass spectrometry detection for the analysis of 39 pesticide residues in porcine meat

    • Journal of Separation Science
    • A rapid and effective method was developed for the analysis of 39 pesticide residues in porcine meat with dual‐layer multi‐plug filtration cleanup and gas chromatography‐tandem mass spectrometry detection. The cleanup process was performed with columns packed with two layers, namely multi‐walled carbon nanotubes, C18 and anhydrous magnesium sulfate (MgSO4) as top layer, while mixture of florisil and MgSO4 as bottom layer.

      • Chemical contaminants
      • Pesticide residues
  7. Combining ultrasound assisted extraction and vortex assisted liquid‐liquid microextraction for the sensitive assessment of aflatoxins in aquaculture fish species

    • Journal of Separation Science
    • Despite aflatoxins contamination in feedstuff is a well‐known problem, and hence these residues are controlled in poultry products, there are scarce information regarding the presence of these toxic substances in aquaculture fish, facilities which use several feedstuff for fish breeding.

      • Aflatoxins
      • Natural toxins
  8. Preparation and application of simetryn‐imprinted nanoparticles in triazine herbicide residue analysis

    • Journal of Separation Science
    • This work provides a simple and rapid method for synthesis uniform simetryn imprinted nanoparticles, which can be used to pretreat the tested samples before detecting. A series of computational approach were employed for design simetryn‐imprinted polymer. Based on the conclusion of theoretical calculation, the simetryn imprinted nanoparticles were synthesized using simetryn as template, methacrylic acid as monomer with different solvent volume and synthesis conditions.

      • Pesticide residues
      • Chemical contaminants
  9. Ligandless, deep eutectic solvent‐based ultrasounds‐assisted dispersive liquid‐liquid microextraction with solidification of the aqueous phase for preconcentration of lead, cadmium, cobalt and nickel in water samples

    • Journal of Separation Science
    • A green and efficient sample preparation method using a deep eutectic solvent‐based ultrasounds‐assisted dispersive liquid–liquid microextraction with solidification of the aqueous phase followed by HPLC analysis was developed for preconcentration and determination of heavy metals in environmental samples.

      • Heavy Metals
      • Chemical contaminants
  10. Supercritical fluid extraction followed by supramolecular solvent microextraction as a fast and efficient preconcentration method for determination of polycyclic aromatic hydrocarbons in apple peels

    • Journal of Separation Science
    • ABSTRACT In this work, reverse micelle‐based supramolecular solvent microextraction method coupled with supercritical fluid extraction and used for determination trace amounts of polycyclic aromatic hydrocarbons in apple peels. The extract was analyzed by high‐performance liquid chromatography equipped with a fluorescence detector.

      • Chemical contaminants
  11. Development of a stir bar sorptive extraction method coupled to solidification of floating droplets dispersive liquid–liquid microextraction based on deep eutectic solvents for the extraction of acidic pesticides from tomato samples

    • Journal of Separation Science
    • A stir bar sorptive extraction method coupled with deep eutectic solvent based solidification of floating organic droplets–dispersive liquid–liquid microextraction has been used for the simultaneous derivatization and extraction of some acidic pesticides in tomato samples. In this method, initially the analytes are adsorbed on a coated stir bar from tomato juice filled in a narrow tube.

      • Pesticide residues
      • Chemical contaminants
  12. Selective extraction of fungicide carbendazim in fruits using β‐cyclodextrin based molecularly imprinted polymers

    • Journal of Separation Science
    • Considering the importance of developing a new analytical approach for pesticide residue detection for the sake of ensuring food safety, a beta‐cyclodextrin based molecularly imprinted polymers were prepared for selective determination of carbendazim. The polymers consist of a porous and hollow structure demonstrating the selective abundant adsorption sites for carbendazim molecule.

      • Pesticide residues
      • Chemical contaminants
  13. Layer‐by‐layer self‐assembly of a novel covalent organic frameworks microextraction coating for analyzing polycyclic aromatic hydrocarbons from aqueous solutions via gas chromatography

    • Journal of Separation Science
    • In this study, a new covalent organic framework, consisting of tetra(4‐aminophenyl)porphyrin and tris(4‐formyl phenyl)amine, was layer‐by‐layer immobilized on stainless‐steel wire as a coating for microextraction. The fabrication process was easy and controllable under mild conditions. The as‐grown extracted fiber was applied to extract polycyclic aromatic hydrocarbons in aqueous solution via head‐space solid‐phase microextraction.

      • Chemical contaminants
  14. Determination of pesticides in dried minor tropical fruits from Colombia using the Quick, Easy, Cheap, Effective, Rugged and Safe method‐gas chromatography tandem mass spectrometry

    • Journal of Separation Science
    • The AOAC 2007.1 Quick, Easy, Cheap, Effective, Rugged and Safe official method, together with gas chromatography coupled to a triple quadrupole mass spectrometer was applied for the analysis of 38 multiclass pesticides from dried fruits typically cultivated and exported from Colombia: uchuva (Physalis peruviana), lulo (Solanum quitoense), guanabana (Anona muricata) and pitahaya (Hylocereus undatus).

      • Chemical contaminants
      • Pesticide residues
  15. Rapid methods for the separation of natural mixtures of beauverolides, cholesterol acyltransferase inhibitors, isolated from the fungus Isaria fumosorosea

    • Journal of Separation Science
    • Beauverolides (beauveriolides) are abundant biologically active cyclodepsipeptides produced by many entomopathogenic fungi, including those that are used as biopesticides. Beauverolides act as cholesterol acyltransferase inhibitors in humans; thus, their mode of action has been the subject of pharmacological and clinical research. The cost‐effective analytical methods are needed for fast, routine laboratory analysis of beauverolides.

      • Chemical contaminants
      • Pesticide residues
  16. Thermo‐sensitive surface molecularly imprinted magnetic microspheres based on bio‐macromolecules and their specific recognition of bovine serum albumin

    • Journal of Separation Science
    • Bovine serum albumin imprinted magnetic microspheres, with functional monomers of modified chitosan, N‐isopropylacrylamide and sulfobetaine methacrylate, were successfully prepared and characterized in detail. Computational analyses showed that during the preparation process, modified chitosan can effortlessly form multiple non‐covalent bonds with protein molecules. Temperature‐sensitive N‐isopropylacrylamide improves the elution efficiency by abating the mass transfer resistance.

      • Chemical contaminants
  17. Highly ordered molecularly imprinted mesoporous silica for selective removal of bisphenol A from wastewater

    • Journal of Separation Science
    • Selective removal of bisphenol A from wastewater is quite challenging primarily because of its low concentration and matrix complexity. To this end, according to the molecular structure of bisphenol A, we designed a functional monomer for the preparation of molecularly imprinted mesoporous silica using click chemistry reaction.

      • Chemical contaminants
  18. Determination of four bisphenols in water and urine samples by magnetic dispersive solid‐phase extraction using a modified zeolite/iron oxide composite prior to liquid chromatography diode array detection

    • Journal of Separation Science
    • A novel approach is presented to determine four bisphenols in water and urine samples, employing magnetic dispersive solid‐phase extraction combined with liquid chromatography and diode array detection. A modified zeolite‐based magnetic composite was used as an efficient sorbent, combining the advantages of magnetic materials with the remarkable properties of zeolites.

      • Chemical contaminants
  19. Towards eco‐friendly secondary plant metabolite quantitation: ultra‐high performance supercritical fluid chromatography applied to common vervain (Verbena officinalis L.)

    • Journal of Separation Science
    • This report presents the first ultra‐high performance supercritical fluid chromatography diode array detector based assay for simultaneous determination of iridoid glucosides, flavonoid glucuronides, and phenylpropanoid glycosides in Verbena officinalis (Verbenaceae) extracts. Separation of the key metabolites was achieved in less than 7 min on an Acquity UPC2 Torus Diol column using a mobile phase gradient comprising subcritical carbon dioxide and methanol with 0.15% phosphoric acid.

  20. Simultaneous determination of multiclass plant growth regulators in fruits using the quick, easy, cheap, effective, rugged, and safe method and ultra high performance liquid chromatography‐tandem mass spectrometry

    • Journal of Separation Science
    • In this study, a modified quick, easy, cheap, effective, rugged, and safe method combined with ultra high performance liquid chromatography‐tandem mass spectrometry was developed for the multiclass determination of 28 plant growth regulators in various fruits. Different extraction solvents and adsorbents, including primary secondary amine, octadecylsilyl, graphitized carbon black, and zirconia‐based sorbent, were investigated.

  21. Organophosphate esters by GC‐MS: an optimized method for aquatic risk assessment

    • Journal of Separation Science
    • ABSTRACT Organophosphate esters used as flame retardants and plasticizers are ubiquitous contaminants in surface waters. Many studies indicate that these compounds are neurotoxicants, endocrine disruptors and may affect reproduction and development of aquatic organisms. Thus, analytical methods that allow accurate quantification of these contaminants at environmentally relevant concentrations are desirable for risk assessment studies.

  22. Multifiber solid phase microextraction using different molecularly imprinted coatings for simultaneous selective extraction and sensitive determination of organophosphorus pesticides

    • Journal of Separation Science
    • Three types of molecularly imprinted solid phase microextraction fibers were fabricated through sol‐gel method using diazinon, parathion‐methyl and isocarbophos as templates, respectively, and assembled together to construct a multifiber for analysis of organophosphorus pesticides in complex matrices. The multifiber provided large extraction capacity and high imprinting factor up to 3.89.

      • Pesticide residues
      • Chemical contaminants
  23. Capillary electrophoresis for the investigation of two novel aminoalkanol derivatives of 1,7‐diethyl‐8,9‐diphenyl‐4‐azatricyclo[5.2.1.02,6] dec‐8‐ene‐3,5,10‐trione as potential anticancer drugs in water solution and serum

    • Journal of Separation Science
    • A simple, rapid, capillary zone electrophoresis method was developed and validated for the analysis the two of novel aminoalkanol derivatives (I) and (II) of 1,7‐diethyl‐8,9‐diphenyl‐4‐azatricyclo[5.2.1.02,6]dec‐8‐ene‐3,5,10‐trione, which were found in earlier studies as potential anticancer drugs. Samples were analyzed to demonstrate the specificity and stability indicating ability of the developed method.

  24. Thermosensitive molecularly imprinted poly(1‐Vinyl‐2‐pyrrolidone/ Methyl methacrylate /N‐vinylcaprolactam) for selective extraction of imatinib mesylate in human biological fluid

    • Journal of Separation Science
    • The efficiency of a molecularly imprinted polymer as a selective packing material for solid‐phase extraction of imatinib mesylate sorption was investigated. Molecularly imprinted polymer was prepared using N, N'‐methylenebisacrylamide, as a cross‐linker agent, N‐vinylcaprolactam as a thermo‐sensitive monomer, 1‐vinyl‐2‐pyrrolidone and methyl methacrylate as functional monomers, azobisisobutyronitrile as an initiator and imatinib mesylate as a template.

      • Chemical contaminants
  25. Chromatography‐An Important Tool for Drug Discovery

    • Journal of Separation Science
    • Despite substantial developments of extraction and separation techniques, isolation of natural products from natural sources is still a challenging task. Undoubtedly hybrid methods like LC‐NMR or LC‐MS made on‐line structure elucidation possible and provided impressive examples of natural product identification without prior isolation, however, in many cases the necessity to get the purified compounds in hand is still a fact.

      • Chemical contaminants
      • Heavy Metals