An official website of the United States government.

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

Food Safety Publications

The Food Safety Publications tracks research that is published across national and international peer-reviewed journals. Recent articles are available ahead of print and searchable by Journal, Article Title, and Category. The research publications are tracked across six categories: Bacterial Pathogens, Chemical Contaminants, Natural Toxins, Parasites, Produce Safety, and Viruses. Articles produced by USDA Grant Funding Agencies and FDA Grant Funding Agencies are also tracked.

Displaying 1 - 25 of 175

  1. Validation of a random Vibrio parahaemolyticus genomic library by selection of quinolone resistance in a heterologous host

    • Wed, 05/11/2022 - 04:00
    • Microbiology
    • is a shellfish-borne pathogen that is a highly prevalent causative agent of inflammatory gastroenteritis in humans. Genomic libraries have proven useful for the identification of novel gene functions in many bacterial species.

      • Bacterial pathogens
      • Vibrio
  2. Topology of the Shigella flexneri Enterobacterial Common Antigen polymerase WzyE

    • Wed, 04/27/2022 - 04:00
    • Microbiology
    • Enterobacteriales have evolved a specialized outer membrane polysaccharide [Enterobacterial Common Antigen (ECA)] which allows them to persist in various environmental niches. Biosynthesis of ECA initiates on the cytoplasmic leaflet of the inner membrane (IM) where glycosyltransferases assemble ECA repeat units (RUs). Complete RUs are then translocated across the IM and assembled into polymers by ECA-specific homologues of the Wzy-dependent pathway.

      • Bacterial pathogens
      • Shigella
  3. Stress response modulation: the key to survival of pathogenic and spoilage bacteria during poultry processing

    • Sat, 04/23/2022 - 04:00
    • Microbiology
    • The control of bacterial contaminants on meat is a key area of interest in the food industry. Bacteria are exposed to a variety of stresses during broiler processing which challenge bacterial structures and metabolic pathways causing death or sublethal injury. To counter these stresses, bacteria possess robust response systems that can induce shifts in the transcriptome and proteome to enable survival.

      • Bacterial pathogens
      • Campylobacter
      • Salmonella
  4. Screening transcriptional connections in Staphylococcus aureus using high-throughput transduction of bioluminescent reporter plasmids

    • Fri, 04/22/2022 - 04:00
    • Microbiology
    • Characterization of transcriptional networks is one of the main strategies used to understand how bacteria interact with their environment.

      • Bacterial pathogens
      • Staphylococcus aureus
  5. Role of horizontally transferred copper resistance genes in Staphylococcus aureus and Listeria monocytogenes

    • Tue, 04/12/2022 - 04:00
    • Microbiology
    • Bacteria have evolved mechanisms which enable them to control intracellular concentrations of metals. In the case of transition metals, such as copper, iron and zinc, bacteria must ensure enough is available as a cofactor for enzymes whilst at the same time preventing the accumulation of excess concentrations, which can be toxic. Interestingly, metal homeostasis and resistance systems have been found to play important roles in virulence.

      • Bacterial pathogens
      • Listeria monocytogenes
      • Staphylococcus aureus
  6. Comparison of Vibrio coralliilyticus virulence in Pacific oyster larvae and corals

    • Wed, 04/06/2022 - 04:00
    • Microbiology
    • The bacterium has been implicated in mass mortalities of corals and shellfish larvae. However, using corals for manipulative infection experiments can be logistically difficult compared to other model organisms, so we aimed to establish oyster larvae infections as a proxy model.

      • Bacterial pathogens
      • Vibrio
  7. Intra-macrophage expression of ArtAB toxin gene in Salmonella

    • Sat, 03/26/2022 - 04:00
    • Microbiology
    • subspecies serovar Typhimurium (. Typhimurium) definitive phage type 104 (DT104), .

      • Bacterial pathogens
      • Salmonella
  8. Hydrogen peroxide, sodium dichloro-s-triazinetriones and quaternary alcohols significantly inactivate the dry-surface biofilms of Staphylococcus aureus and Pseudomonas aeruginosa more than quaternary ammoniums

    • Sat, 03/12/2022 - 12:00
    • Microbiology
    • Globally, healthcare-associated infections (HAI) are the most frequent adverse outcome in healthcare delivery. Although bacterial biofilms contribute significantly to the incidence of HAI, few studies have investigated the efficacy of common disinfectants against dry-surface biofilms (DSB).

      • Bacterial pathogens
      • Staphylococcus aureus
  9. Transient internalization of Campylobacter jejuni in Amoebae enhances subsequent invasion of human cells

    • Fri, 02/18/2022 - 06:00
    • Microbiology
    • The ubiquitous unicellular eukaryote, , is known to play a role in the survival and dissemination of is the leading cause of bacterial foodborne gastroenteritis world-wide and is a major public health problem. The ability of

      • Bacterial pathogens
      • Campylobacter
  10. Presence of optrA-mediated linezolid resistance in multiple lineages and plasmids of Enterococcus faecalis revealed by long read sequencing

    • Tue, 02/08/2022 - 12:00
    • Microbiology
    • Transferable linezolid resistance due to , , and -like genes is increasingly detected in enterococci associated with animals and humans globally.

      • Chemical contaminants
      • Antibiotic residues
      • Dioxins
  11. Genetic and mutational analysis of virulence traits and their modulation in an environmental toxigenic Vibrio cholerae non-O1/non-O139 strain, VCE232

    • Fri, 02/04/2022 - 06:00
    • Microbiology
    • O1 and O139 isolates deploy cholera toxin (CT) and toxin-coregulated pilus (TCP) to cause the diarrhoeal disease cholera.

      • Bacterial pathogens
      • Vibrio
  12. Predatory bacteria in the haemolymph of the cultured spiny lobster Panulirus ornatus

    • Thu, 01/13/2022 - 12:01
    • Microbiology
    • Bdellovibrio and like organisms (BALOs) are a group of Gram-negative bacteria that prey on other Gram-negative bacteria.

      • Bacterial pathogens
      • Vibrio
  13. Cell-free supernatants produced by lactic acid bacteria reduce Salmonella population in vitro

    • Thu, 01/13/2022 - 12:01
    • Microbiology
    • The genus is closely associated with foodborne outbreaks and animal diseases, and reports of antimicrobial resistance in species are frequent.

      • Bacterial pathogens
      • Salmonella
  14. Alanine-scanning mutagenesis of protein mannosyl-transferase from Streptomyces coelicolor reveals strong activity-stability correlation

    • Wed, 01/12/2022 - 22:17
    • Microbiology
    • In , protein O-mannosyl transferase (Pmt)-mediated protein O-glycosylation has an important role in cell envelope physiology. In defective Pmt leads to increased susceptibility to cell wall-targeting antibiotics, including vancomycin and β-lactams, and resistance to phage ϕC31.

      • Chemical contaminants
      • Antibiotic residues
  15. Two regulatory factors of Vibrio cholerae activating the mannose-sensitive haemagglutinin pilus expression is important for biofilm formation and colonization in mice

    • Wed, 01/12/2022 - 22:17
    • Microbiology
    • the causative agent of cholera, uses a large number of coordinated transcriptional regulatory events to transition from its environmental reservoir to the host intestine, which is its preferred colonization site.

      • Bacterial pathogens
      • Vibrio
  16. Topological analysis of a bacterial DedA protein associated with alkaline tolerance and antimicrobial resistance

    • Wed, 01/12/2022 - 22:17
    • Microbiology
    • Maintaining membrane integrity is of paramount importance to the survival of bacteria as the membrane is the site of multiple crucial cellular processes including energy generation, nutrient uptake and antimicrobial efflux. The DedA family of integral membrane proteins are widespread in bacteria and are associated with maintaining the integrity of the membrane. In addition, DedA proteins have been linked to resistance to multiple classes of antimicrobials in various microorganisms.

      • Chemical contaminants
      • Antibiotic residues
  17. Impact of growth media and pressure on the diversity and antimicrobial activity of isolates from two species of hexactinellid sponge

    • Wed, 01/12/2022 - 22:17
    • Microbiology
    • Access to deep-sea sponges brings with it the potential to discover novel antimicrobial candidates, as well as novel cold- and pressure-adapted bacteria with further potential clinical or industrial applications.

      • Bacterial pathogens
      • Staphylococcus aureus
  18. Significant variability exists in the cytotoxicity of global methicillin-resistant Staphylococcus aureus lineages

    • Wed, 01/12/2022 - 22:17
    • Microbiology
    • is a major human pathogen where the emergence of antibiotic resistant lineages, such as methicillin-resistant (MRSA), is a major health concern.

      • Bacterial pathogens
      • Staphylococcus aureus
  19. Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147

    • Wed, 01/12/2022 - 19:22
    • Microbiology
    • The rapid emergence of multidrug-resistant is being driven largely by the spread of specific clonal groups (CGs). Of these, CG147 includes 7-gene multilocus sequence typing (MLST) sequence types (STs) ST147, ST273 and ST392.

      • Bacterial pathogens
  20. Evaluation of the virucidal efficacy of Klaran UVC LEDs against surface-dried norovirus

    • Wed, 01/12/2022 - 19:22
    • Microbiology
    • Human norovirus (HuNoV) is a highly contagious pathogenic virus that is transmitted through contaminated food, water, high-touch surfaces and aerosols. Globally, there are an estimated 685 million infections annually due to norovirus, including 200 million affecting children under the age of 5. HuNoV causes approximately 50, 000 child deaths per year and costs an estimated USD $60 billion annually in healthcare.

      • Norovirus
      • Viruses
  21. The human bile salt sodium deoxycholate induces metabolic and cell envelope changes in Salmonella Typhi leading to bile resistance

    • Tue, 01/11/2022 - 03:00
    • Microbiology
    • serovar Typhi (. Typhi) is the etiological agent of typhoid fever. To establish an infection in the human host, this pathogen must survive the presence of bile salts in the gut and gallbladder.

      • Salmonella
      • Bacterial pathogens
  22. qnrA gene diversity in Shewanella spp.

    • Fri, 12/17/2021 - 03:01
    • Microbiology
    • Members of are ubiquitous in aquatic environments, some of which have been implicated in human infections. The progenitors of antibiotic resistance genes with clinical relevance, such as genes, have been identified in

  23. Topological analysis of a bacterial DedA protein associated with alkaline tolerance and antimicrobial resistance

    • Fri, 12/17/2021 - 03:01
    • Microbiology
    • Maintaining membrane integrity is of paramount importance to the survival of bacteria as the membrane is the site of multiple crucial cellular processes including energy generation, nutrient uptake and antimicrobial efflux. The DedA family of integral membrane proteins are widespread in bacteria and are associated with maintaining the integrity of the membrane. In addition, DedA proteins have been linked to resistance to multiple classes of antimicrobials in various microorganisms.

      • Antibiotic residues
      • Bacterial pathogens
      • Chemical contaminants
  24. Genomic comparisons of Escherichia coli ST131 from Australia

    • Thu, 12/16/2021 - 03:01
    • Microbiology
    • ST131 is a globally dispersed extraintestinal pathogenic lineage contributing significantly to hospital and community acquired urinary tract and bloodstream infections.

      • Bacterial pathogens
  25. Prophages encoding human immune evasion cluster genes are enriched in Staphylococcus aureus isolated from chronic rhinosinusitis patients with nasal polyps

    • Thu, 12/16/2021 - 03:01
    • Microbiology
    • Prophages affect bacterial fitness on multiple levels. These include bacterial infectivity, toxin secretion, virulence regulation, surface modification, immune stimulation and evasion and microbiome competition. Lysogenic conversion arms bacteria with novel accessory functions thereby increasing bacterial fitness, host adaptation and persistence, and antibiotic resistance.

      • Staphylococcus aureus
      • Bacterial pathogens