7th Annual 3Rs Symposium: Practical Solutions and Success Stories

The following are a selection of presentations from a symposium that was co-hosted by the USDA Animal Welfare Information Center (AWIC), NIH Office of Laboratory Animal Welfare (OLAW), the Johns Hopkins Department of Molecular and Comparative Pathobiology, and the Johns Hopkins Center for Alternatives to Animal Testing (CAAT), held online on June 4-5, 2020. The goal of this year’s symposium was to bring together experts in replacement, reduction, and refinement of animal experimentation to exchange information with scientists, Institutional Animal Care and Use Committee (IACUC) members, veterinarians, and animal care technicians about practical solutions and recent success stories to reduce the use of animals in research and improve their welfare.

These presentations are being hosted by Animal Welfare Information Center, a service of The National Agricultural Library. Staff do not edit or otherwise modify the original materials. The views expressed in the presentations do not necessarily reflect the policies of the National Agricultural Library or the United States Department of Agriculture.

The 2020 Symposium on Social Housing of Laboratory Animals playlist can be viewed on YouTube or as individual videos below.

Organizer’s Welcome Speaker: Kristina Adams, Patricia Brown, Kathrin Herrmann, Eric Hutchinson

Beyond Zoonoses: The Crucial Connection Between Humans, Animal And Non-Communicable Diseases Speaker: Barbara Natterson-Horowitz

Minibrain Organoids Speaker: Helena Hogberg

Innovative Models in Biomedical Research: A Literature Review Speaker: Laura Gribaldo

Grimace Scale Panel Speakers: Grimace Scale Panel

Grimace Scale Panel - Part 2 Speakers: Anne Burrows & Dale Langford

Improving Design and Reporting Animal Experiments: Experimental Design Assistant/ARRIVE Guidelines Speaker: Nathalie Percie du Sert

PREPARE Guidelines Speaker: Adrian Smith

NINDS/NIH Approach to Rigor and Transparency Speaker: Shai Silberberg

Q&A Hot Topics: Best Data from Design to Publish Speakers: Adrian Smith, Nathalie Percie du Sert, Shai Silberberg

Refinement WIKI and International Culture of Care Network (including Q&A) Speaker: Adrian Smith

The Center for Open Science: openness, integrity, and reproducibility of research Speaker: Cynthia (Cyndy) Parr

The PRIMatE Data Exchange: An Open Science Resource for Non-human Primate Imaging Speaker: Michael Milham

How Dogs are Helping Us Understand Cancer Speaker: Amy LeBlanc

Image Guided Animal Therapy Speaker: Dara Kraitchman

Practical Solutions: Panel Q&A Speaker: Amy LeBlanc & Dara Kraitchman

Behavioral Training as Part of the Health Care Program Speaker: Steven Schapiro

Pig Handling Speaker: Derek Brocksmith

Hydrophobic Sand as an Alternative to Metabolic Cages Speaker: Jessica Hoffman

Panel Q & A - DAY 2 Schapiro, Brocksmith, Hoffman Speakers: Steven Schapiro, Derek Brocksmith, Jessica Hoffman

Mouse Handling Limits the Impact of Stress on Metabolic Endpoints Speaker: Parinaz Mahbod

State of the Art Rodent Handling: Can a Little Time Go a Long Way for Welfare? Speaker: Brianna N. Gaskill

Panel Q&A -- Rodent Handling Speakers: Parinaz Mahbod, Brianna N. Gaskill