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Assessment of Nephrotoxicity from an Exposure to Melamine, Cyanuric acid, and its combination in Newborn F344 Rats from Postnatal Day-1 to Weaning


<li>Determine if a combined exposure to melamine and cyanuric acid in newborn F344 rats is more nephrotoxic than exposure to the individual compounds.</li>
<li>Establish the dose-response curve for the combined exposure.</li>
<li>Investigate the longer-term effects during a recovery period.</li></ol></p>

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Responsible Office: Biochemical Toxicology

Gamboa da Costa, Goncalo
DHHS/FDA - National Center for Toxicological Research
DHHS/FDA - Center for Food Safety & Applied Nutrition
DHHS- National Toxicology Program
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